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The map label for this gene is dtd [H]

Identifier: 157963717

GI number: 157963717

Start: 4752644

End: 4753081

Strand: Reverse

Name: dtd [H]

Synonym: Spea_3906

Alternate gene names: 157963717

Gene position: 4753081-4752644 (Counterclockwise)

Preceding gene: 157963718

Following gene: 157963716

Centisome position: 91.85

GC content: 47.03

Gene sequence:

>438_bases
GTGATAGCCCTTATTCAACGTGTGAGTGAAGCAAAAGTTGTCGTTGATGGCGCGACTATCGGTGAGATCGATAAAGGTCT
GTTGGTGTTACTCGGTGTTGAGCGCGAGGATAACATTGAAAAGATGCAAAAGTTGGCCACTAAGGTGATGAGTTACCGTG
TGTTTTCCGATGAGAATGGCAAGATGAATCTTAACCTTGAGCAAGCGGGTGGCAGCTTACTTGTGGTCTCGCAATTTACC
TTGGCAGCCGATACTGGCCGAGGCTTACGCCCAAGCTTTTCAGGCGCCGGCACACCAGATCAAGCCCGTGAACTTTATGA
AGCCTTTGTCGATTTTTGTAAATCAAAAGGGGTCAACACCCAAACCGGTCAATTTGCCGCAGATATGAAAGTGTCTTTAG
TTAACGACGGCCCAGTGACTTTTAATTTGCAGGTTTAG

Upstream 100 bases:

>100_bases
CTCGAAGCGAAGCGTCCTAGGATCTAGGTCCTTCTTTTAAAGCGAAGCGTTCGTCTTCGCTTTTTCATTTCAGTTATTAA
TTTTTTTGGAGAGTGTGTAG

Downstream 100 bases:

>100_bases
ATATCTAGGTCGGACTACGGGGATTATAAGAGCTAGAACAGGAAAGCAGATGAAAGATTTAAACCATCAAACCTTGCTAG
AACAACTGCAGCAGACTTGG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVSEAKVVVDGATIGEIDKGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQARELYEAFVDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV

Sequences:

>Translated_145_residues
MIALIQRVSEAKVVVDGATIGEIDKGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQARELYEAFVDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV
>Mature_145_residues
MIALIQRVSEAKVVVDGATIGEIDKGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQARELYEAFVDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=36.0544217687075, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=65.5172413793103, Blast_Score=199, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=39.1891891891892, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=40.4109589041096, Blast_Score=108, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=36.986301369863, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15631; Mature: 15631

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSEAKVVVDGATIGEIDKGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENG
CHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQARELYEAFVDFCKSKGVNT
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
QTGQFAADMKVSLVNDGPVTFNLQV
CCCCEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSEAKVVVDGATIGEIDKGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENG
CHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQARELYEAFVDFCKSKGVNT
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
QTGQFAADMKVSLVNDGPVTFNLQV
CCCCEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA