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The map label for this gene is argA [H]

Identifier: 157963645

GI number: 157963645

Start: 4661631

End: 4662953

Strand: Reverse

Name: argA [H]

Synonym: Spea_3834

Alternate gene names: 157963645

Gene position: 4662953-4661631 (Counterclockwise)

Preceding gene: 157963646

Following gene: 157963644

Centisome position: 90.11

GC content: 47.54

Gene sequence:

>1323_bases
GTGCGTACTACTGAACTTGTTGATGGATTTCGTCATTCTGCTTCCTATGTTAATGCCCATAGGGGCAAGACCTTCGTTGT
GATGCTCGGCGGTGAAGCGCTGGCACAGCAACAGTTTCGCGCGATTATCAATGATATTGCACTATTGCACAGCTTAGGGA
TCAAAATAGTCTTAGTTCACGGTGCTAGGCCGCAGATTGATGAAGCGCTGGAGCAGCATAGTCTGGCAGCCGAATATTAC
AATGGTGTGAGGGTGACAGATGAAGATGCCCTTAAAGTGATTAAACAAGTGGTTGGCGGCTTACATCTTGATATCACGGC
CCGCCTGTCGATGAGCCTCAGCAATACTCCGATGCAGGGGGCACAAATTAACGTTGTCAGTGGTAATTTTGTGATTGCAC
AGCCGTTAGGGGTTGAGGATGGTATTGATTATTGCCTCAGCGGTAAGGTGCGTCGAATCGATAGCCAAGGTTTGAAGCGT
CAGCTTGATAATGGCGGTATCGTGTTGTTAGGCCCTGTAGCGGCCTCAGTGACGGGTGAGAGCTTTAATCTGACTGCGGA
AGAGGTAGCCACTCAGATTGCAATAAAACTCAAAGCAGACAAGATGATAGGCTTTAGTGCTCAGAAGGGGATTTTGGATA
GCGACGGACAAGTTATGGCAGAGCTGATGCCTACCGAAGCGCAAAAAATCTTAAATGATTTCCCTGAGGTTTCTCCCTTA
TGTGTAGGTACTAAGGCATTTTTAGAGGCCAGTATCGATGCCTGCCGTAACGGGGTGAGTCGCTGCCATTTTGTCAGTTA
TCTCGATGATGGAGCACTGTTACAAGAGTTGTTCTCGCGCGACGGTATTGGTACTCAAATTGTCACTGAGAGTGCCGAAC
GTTTACGTAGAGCGTCGATTAGCGATATTGGCGGCGTGCTTGACCTTATTCGTCCACTCGAGCAGAAAGGGATCTTAGTG
CGGCGTTCACGTGAACAACTGGAGATGGAGATAGAGCAATTTATGCTGATTGAGCGTGATAGTTTGGTCATAGGCTGCGC
GGCATTTTATCCTTTTGAAGAGGACAATGCGGGGGAGTTTGCCTGTTTAGTGGTGCACCCCGACTACCGTGATGCCGATA
GAGGTAGCTTGCTACTACAAAATATTATTAGTCAGGCAAGAGTGAGAGGTTATTCGCGTTTGTTTGCCTTAACCACTCGC
AGTATCCATTGGTTCTTAGAGCACGGCTTTAATATGGTCGAGGTTGATGCGCTGCCAGAGAAGAAAAAGCAGCTGTATAA
CTATCAACGCAAATCGAAGATTTTAGCGCTAGACTTAGACTGA

Upstream 100 bases:

>100_bases
AAATGAATTTAAATGCAATATCATCTTTGTAAGTTGCTGGCTTAATGTGTAATGGCTGGCTGTTCAGGTGAATATCTATT
TATTTTAAGGTGATTCTAGC

Downstream 100 bases:

>100_bases
TTGGTATTAGAGGCTGACTAGAGTGTTGGCATCTAAAACTCTGGTTATCATCGTAAATTAGGAGCCGCCATGCCTCAAGT
TTATGCATTGGCACCACTCA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEALAQQQFRAIINDIALLHSLGIKIVLVHGARPQIDEALEQHSLAAEYY
NGVRVTDEDALKVIKQVVGGLHLDITARLSMSLSNTPMQGAQINVVSGNFVIAQPLGVEDGIDYCLSGKVRRIDSQGLKR
QLDNGGIVLLGPVAASVTGESFNLTAEEVATQIAIKLKADKMIGFSAQKGILDSDGQVMAELMPTEAQKILNDFPEVSPL
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRASISDIGGVLDLIRPLEQKGILV
RRSREQLEMEIEQFMLIERDSLVIGCAAFYPFEEDNAGEFACLVVHPDYRDADRGSLLLQNIISQARVRGYSRLFALTTR
SIHWFLEHGFNMVEVDALPEKKKQLYNYQRKSKILALDLD

Sequences:

>Translated_440_residues
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEALAQQQFRAIINDIALLHSLGIKIVLVHGARPQIDEALEQHSLAAEYY
NGVRVTDEDALKVIKQVVGGLHLDITARLSMSLSNTPMQGAQINVVSGNFVIAQPLGVEDGIDYCLSGKVRRIDSQGLKR
QLDNGGIVLLGPVAASVTGESFNLTAEEVATQIAIKLKADKMIGFSAQKGILDSDGQVMAELMPTEAQKILNDFPEVSPL
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRASISDIGGVLDLIRPLEQKGILV
RRSREQLEMEIEQFMLIERDSLVIGCAAFYPFEEDNAGEFACLVVHPDYRDADRGSLLLQNIISQARVRGYSRLFALTTR
SIHWFLEHGFNMVEVDALPEKKKQLYNYQRKSKILALDLD
>Mature_440_residues
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEALAQQQFRAIINDIALLHSLGIKIVLVHGARPQIDEALEQHSLAAEYY
NGVRVTDEDALKVIKQVVGGLHLDITARLSMSLSNTPMQGAQINVVSGNFVIAQPLGVEDGIDYCLSGKVRRIDSQGLKR
QLDNGGIVLLGPVAASVTGESFNLTAEEVATQIAIKLKADKMIGFSAQKGILDSDGQVMAELMPTEAQKILNDFPEVSPL
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRASISDIGGVLDLIRPLEQKGILV
RRSREQLEMEIEQFMLIERDSLVIGCAAFYPFEEDNAGEFACLVVHPDYRDADRGSLLLQNIISQARVRGYSRLFALTTR
SIHWFLEHGFNMVEVDALPEKKKQLYNYQRKSKILALDLD

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=438, Percent_Identity=64.3835616438356, Blast_Score=607, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6320913, Length=314, Percent_Identity=21.0191082802548, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 48531; Mature: 48531

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEALAQQQFRAIINDIALLHSLGIKIVLVH
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GARPQIDEALEQHSLAAEYYNGVRVTDEDALKVIKQVVGGLHLDITARLSMSLSNTPMQG
CCCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCC
AQINVVSGNFVIAQPLGVEDGIDYCLSGKVRRIDSQGLKRQLDNGGIVLLGPVAASVTGE
CEEEEEECCEEEEECCCCCCCCHHHHCCCCEEHHHHHHHHHHCCCCEEEECCCEEEECCC
SFNLTAEEVATQIAIKLKADKMIGFSAQKGILDSDGQVMAELMPTEAQKILNDFPEVSPL
CCCCCHHHHHHHHHEEEECCCEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCE
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRASI
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDIGGVLDLIRPLEQKGILVRRSREQLEMEIEQFMLIERDSLVIGCAAFYPFEEDNAGEF
HHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCCCE
ACLVVHPDYRDADRGSLLLQNIISQARVRGYSRLFALTTRSIHWFLEHGFNMVEVDALPE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCH
KKKQLYNYQRKSKILALDLD
HHHHHHHHHHHCEEEEEECC
>Mature Secondary Structure
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEALAQQQFRAIINDIALLHSLGIKIVLVH
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GARPQIDEALEQHSLAAEYYNGVRVTDEDALKVIKQVVGGLHLDITARLSMSLSNTPMQG
CCCCCHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCC
AQINVVSGNFVIAQPLGVEDGIDYCLSGKVRRIDSQGLKRQLDNGGIVLLGPVAASVTGE
CEEEEEECCEEEEECCCCCCCCHHHHCCCCEEHHHHHHHHHHCCCCEEEECCCEEEECCC
SFNLTAEEVATQIAIKLKADKMIGFSAQKGILDSDGQVMAELMPTEAQKILNDFPEVSPL
CCCCCHHHHHHHHHEEEECCCEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCCCCE
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRASI
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDIGGVLDLIRPLEQKGILVRRSREQLEMEIEQFMLIERDSLVIGCAAFYPFEEDNAGEF
HHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCCCE
ACLVVHPDYRDADRGSLLLQNIISQARVRGYSRLFALTTRSIHWFLEHGFNMVEVDALPE
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCH
KKKQLYNYQRKSKILALDLD
HHHHHHHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]