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The map label for this gene is ftsA [H]

Identifier: 157963619

GI number: 157963619

Start: 4630315

End: 4631550

Strand: Reverse

Name: ftsA [H]

Synonym: Spea_3808

Alternate gene names: 157963619

Gene position: 4631550-4630315 (Counterclockwise)

Preceding gene: 157963620

Following gene: 157963618

Centisome position: 89.51

GC content: 48.54

Gene sequence:

>1236_bases
ATGACCAAGAATCTGGATAGAAATCTGATCGTGGGATTGGACATAGGGACATCAAAGGTCGCTGTCATCATTGGTGAAGT
GTTGCCTGACGGTGAGATCAGTATTGTCGGCCTTGGAAACCATCCTTCAAGAGGTATGGATAAAGGCGGCGTTAACGACC
TCGACTCTATCGTTCGCAGTGTACAAAGAGCACTGGATCAAGCTGAACTAATGGCTGATTGCCAAGTCTCATCGGTTTAT
TTGAGTATTTCGGGTAAACATATCGAATGCCAGAATGAAAACGGCATGGTATCGATTAATGATGAAGAAGTGACGCAAGA
AGACGTCGACAACGTGATTCATACCGCGCGTTCAGTAAAGATCCCAACAGAACGTCGTATCTTGCATGTGTTGCCGCAAG
AATACGCTATCGATATTCAAGACGGCATTAAGAGCCCGATAGGCATGTCTGGTATGCGTATGGAAGCTAAGGTGCATATC
GTGACTTGCGCTAATGATATGGCTAAGAATATCACTAAGAGCGTAGAGCGCTGTGGCTTGAAGGTTGATGACCTAGTGTT
CTCAGCGATTGCATCTGCCGACTCAGTGCTGACAGATGATGAGAAAGACTTAGGTGTCTGTTTAGTTGATATTGGCGGTG
GCACAACAGATATCGCTGTTTATACCAATGGCGCGCTGCGTCATTGTGCAGTGGTGCCGGTTGCGGGTAATCAGGTGACT
AACGATATCGCTAAGATATTCCGCACACCATTATCTCATGCGGAGCAGATTAAGGTGCAGCACGCTAGCGCTCGTAGCGC
TATGGTGAGCCGTGAAGACAGTATTGAAGTTCCGTCGGTAGGCGGTCGCCCTTCACGCAGTATGTCGCGTCACACGTTGG
CAGAAGTGGTGGAGCCAAGATACCAAGAATTATTTGAACTGATCTTAAAGCAGCTACGCGATAGCGGGCTCGAAGATCAG
GTTGCAGCGGGCATAGTGATCACTGGTGGCACAGCATCGATTGAAGGTGCTGTGGATATCGCTGAAGCAACATTTGGCAT
GCCAGTACGAATGGCACAGCCGCTGCCAGTAAAAGGTTTACATGAATATGTGGATCAACCTATTTACTCTACCGGAGTCG
GGTTGCTTCACTATGGTGCGCGCAGAGTGATCGAACGTCAGTTCGAGCGTCCTGAGCGACAAGGGGTCACCAGTCTTTGG
AATCGGGTCCAGAGTTGGTTTAAAGGCGAGTTTTAG

Upstream 100 bases:

>100_bases
ACTTGCTAAGCAAGAAAAGAAGGTAGCGATTGTGGATTTGCGCTACGACACAGGTTTGGCCGTAGGTTGGGATGATGCAC
AGAAAGAGAGCCGTTAATTA

Downstream 100 bases:

>100_bases
TTAATAACGCAGGCAGAACGGAGAAAAGACCATGTTTGAGATCATGGATAGTCATTCAGACGAGGCGGTGATTAAGGTCA
TCGGCGTCGGTGGCGGCGGT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTKNLDRNLIVGLDIGTSKVAVIIGEVLPDGEISIVGLGNHPSRGMDKGGVNDLDSIVRSVQRALDQAELMADCQVSSVY
LSISGKHIECQNENGMVSINDEEVTQEDVDNVIHTARSVKIPTERRILHVLPQEYAIDIQDGIKSPIGMSGMRMEAKVHI
VTCANDMAKNITKSVERCGLKVDDLVFSAIASADSVLTDDEKDLGVCLVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVT
NDIAKIFRTPLSHAEQIKVQHASARSAMVSREDSIEVPSVGGRPSRSMSRHTLAEVVEPRYQELFELILKQLRDSGLEDQ
VAAGIVITGGTASIEGAVDIAEATFGMPVRMAQPLPVKGLHEYVDQPIYSTGVGLLHYGARRVIERQFERPERQGVTSLW
NRVQSWFKGEF

Sequences:

>Translated_411_residues
MTKNLDRNLIVGLDIGTSKVAVIIGEVLPDGEISIVGLGNHPSRGMDKGGVNDLDSIVRSVQRALDQAELMADCQVSSVY
LSISGKHIECQNENGMVSINDEEVTQEDVDNVIHTARSVKIPTERRILHVLPQEYAIDIQDGIKSPIGMSGMRMEAKVHI
VTCANDMAKNITKSVERCGLKVDDLVFSAIASADSVLTDDEKDLGVCLVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVT
NDIAKIFRTPLSHAEQIKVQHASARSAMVSREDSIEVPSVGGRPSRSMSRHTLAEVVEPRYQELFELILKQLRDSGLEDQ
VAAGIVITGGTASIEGAVDIAEATFGMPVRMAQPLPVKGLHEYVDQPIYSTGVGLLHYGARRVIERQFERPERQGVTSLW
NRVQSWFKGEF
>Mature_410_residues
TKNLDRNLIVGLDIGTSKVAVIIGEVLPDGEISIVGLGNHPSRGMDKGGVNDLDSIVRSVQRALDQAELMADCQVSSVYL
SISGKHIECQNENGMVSINDEEVTQEDVDNVIHTARSVKIPTERRILHVLPQEYAIDIQDGIKSPIGMSGMRMEAKVHIV
TCANDMAKNITKSVERCGLKVDDLVFSAIASADSVLTDDEKDLGVCLVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVTN
DIAKIFRTPLSHAEQIKVQHASARSAMVSREDSIEVPSVGGRPSRSMSRHTLAEVVEPRYQELFELILKQLRDSGLEDQV
AAGIVITGGTASIEGAVDIAEATFGMPVRMAQPLPVKGLHEYVDQPIYSTGVGLLHYGARRVIERQFERPERQGVTSLWN
RVQSWFKGEF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=420, Percent_Identity=60.4761904761905, Blast_Score=528, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 44645; Mature: 44514

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNLDRNLIVGLDIGTSKVAVIIGEVLPDGEISIVGLGNHPSRGMDKGGVNDLDSIVRS
CCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
VQRALDQAELMADCQVSSVYLSISGKHIECQNENGMVSINDEEVTQEDVDNVIHTARSVK
HHHHHHHHHHHHCCEEEEEEEEECCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHCC
IPTERRILHVLPQEYAIDIQDGIKSPIGMSGMRMEAKVHIVTCANDMAKNITKSVERCGL
CCHHHHHHHHCCHHHEEEHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHCC
KVDDLVFSAIASADSVLTDDEKDLGVCLVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVT
CHHHHHHHHHHCCCHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEECCCHHH
NDIAKIFRTPLSHAEQIKVQHASARSAMVSREDSIEVPSVGGRPSRSMSRHTLAEVVEPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHH
YQELFELILKQLRDSGLEDQVAAGIVITGGTASIEGAVDIAEATFGMPVRMAQPLPVKGL
HHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCCCHHHHHHHHCCCCEECCCCCCHHHH
HEYVDQPIYSTGVGLLHYGARRVIERQFERPERQGVTSLWNRVQSWFKGEF
HHHHCCCHHHHCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKNLDRNLIVGLDIGTSKVAVIIGEVLPDGEISIVGLGNHPSRGMDKGGVNDLDSIVRS
CCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
VQRALDQAELMADCQVSSVYLSISGKHIECQNENGMVSINDEEVTQEDVDNVIHTARSVK
HHHHHHHHHHHHCCEEEEEEEEECCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHCC
IPTERRILHVLPQEYAIDIQDGIKSPIGMSGMRMEAKVHIVTCANDMAKNITKSVERCGL
CCHHHHHHHHCCHHHEEEHHHHCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHCC
KVDDLVFSAIASADSVLTDDEKDLGVCLVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVT
CHHHHHHHHHHCCCHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEECCCHHH
NDIAKIFRTPLSHAEQIKVQHASARSAMVSREDSIEVPSVGGRPSRSMSRHTLAEVVEPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHH
YQELFELILKQLRDSGLEDQVAAGIVITGGTASIEGAVDIAEATFGMPVRMAQPLPVKGL
HHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCCCCHHHHHHHHCCCCEECCCCCCHHHH
HEYVDQPIYSTGVGLLHYGARRVIERQFERPERQGVTSLWNRVQSWFKGEF
HHHHCCCHHHHCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]