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The map label for this gene is 157963549

Identifier: 157963549

GI number: 157963549

Start: 4542253

End: 4543290

Strand: Reverse

Name: 157963549

Synonym: Spea_3737

Alternate gene names: NA

Gene position: 4543290-4542253 (Counterclockwise)

Preceding gene: 157963550

Following gene: 157963548

Centisome position: 87.8

GC content: 45.09

Gene sequence:

>1038_bases
ATGGGTATTTTTGAACGTTATTTAAGTGTTTGGGTTGGTCTGGCTATTCTAGCTGGTGTGTTTCTGGGTAACTTAGCGCC
AGACACATTTACAGTGATAGCTGGGCTTGAATATGCTCATGTGAATTTTGTCATTGCGGTACTGATTTGGGTGATGATTT
ATCCAATGATGGTGCAAATCGACTTTTCAGCAGTGAAAGATGTGGGTAAAAGCCCAAAAGGTCTAGTACTGACATTAGTA
ATTAATTGGTTGATTAAGCCCTTTACTATGGCTGCATTAGGCTGGTTATTCTTTAAGGTGTTCTTTGTCGATTTTGTCGA
CCCACAAACGGCGAGTGAATACATTGCGGGTATGATATTACTGGGCGTCGCACCTTGTACGGCTATGGTCTTTGTCTGGA
GCCAGCTCACAAAAGGCGACCCCAACTACACCTTAGTACAGGTCTCGGTAAATGATTTAATCATGGTGGTGGCATTTGCC
CCAATCACTGCATTGCTATTGGGCGTGAGTGATATTCAGGTGCCATGGGCGACCTTGTTATCATCAGTCGGTTTATATGT
GGTGTTGCCATTGATTGCAGGTGTTATCACCCGATATATGCTGCAGAAAAAGGGCGACGATAGTCAGGTAAACGCATTTG
TGGCTAAGCTGAAGCCTTGGTCTATGGTGGGGCTGCTTGCCACTGTGGTGCTGCTATTTGGCTTTCAGGCTGAAACAATT
ATTGCTGAGCCACAAAATATTGCCCTGATTGCGATTCCGTTATTGATCCAAACTTACGGTATTTTCTTTATCGCATTTTA
TGCGGCTAAAAAGATGAAGCTAACTCATAAAGTGGCGGCGCCAGCTTGTATGATTGCCACTTCAAACTTCTTTGAATTAG
CTGTGGCGGTAGCCATCTCACTGTTTGGCTTGCATTCGGGGGCTGCGCTAGCCACTGTGGTTGGCGTGCTAGTGGAGGTG
CCAGTGATGTTATCGTTAGTGGCGATAGTTAACCGCAGTCGGCATCTATTTGCTGAAGATGCAGTTACTCAGTCGTAA

Upstream 100 bases:

>100_bases
AAATAAGCTCCTACAGATGGGCTCTCGTCCAGAACGGACTAAAGTCTGCTGCTAATCGGTATTTTGTTTGACTATTTTTA
ATCATATTAGGCTACATACA

Downstream 100 bases:

>100_bases
TCGCTAGCTCAGAGCTTATGCTCTGAGCATCAAATCCGGCTATTACATTGAGAAATAAATTCTAACTCTAGATTGAACTT
AAACGATTTAATAACAGATT

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MGIFERYLSVWVGLAILAGVFLGNLAPDTFTVIAGLEYAHVNFVIAVLIWVMIYPMMVQIDFSAVKDVGKSPKGLVLTLV
INWLIKPFTMAALGWLFFKVFFVDFVDPQTASEYIAGMILLGVAPCTAMVFVWSQLTKGDPNYTLVQVSVNDLIMVVAFA
PITALLLGVSDIQVPWATLLSSVGLYVVLPLIAGVITRYMLQKKGDDSQVNAFVAKLKPWSMVGLLATVVLLFGFQAETI
IAEPQNIALIAIPLLIQTYGIFFIAFYAAKKMKLTHKVAAPACMIATSNFFELAVAVAISLFGLHSGAALATVVGVLVEV
PVMLSLVAIVNRSRHLFAEDAVTQS

Sequences:

>Translated_345_residues
MGIFERYLSVWVGLAILAGVFLGNLAPDTFTVIAGLEYAHVNFVIAVLIWVMIYPMMVQIDFSAVKDVGKSPKGLVLTLV
INWLIKPFTMAALGWLFFKVFFVDFVDPQTASEYIAGMILLGVAPCTAMVFVWSQLTKGDPNYTLVQVSVNDLIMVVAFA
PITALLLGVSDIQVPWATLLSSVGLYVVLPLIAGVITRYMLQKKGDDSQVNAFVAKLKPWSMVGLLATVVLLFGFQAETI
IAEPQNIALIAIPLLIQTYGIFFIAFYAAKKMKLTHKVAAPACMIATSNFFELAVAVAISLFGLHSGAALATVVGVLVEV
PVMLSLVAIVNRSRHLFAEDAVTQS
>Mature_344_residues
GIFERYLSVWVGLAILAGVFLGNLAPDTFTVIAGLEYAHVNFVIAVLIWVMIYPMMVQIDFSAVKDVGKSPKGLVLTLVI
NWLIKPFTMAALGWLFFKVFFVDFVDPQTASEYIAGMILLGVAPCTAMVFVWSQLTKGDPNYTLVQVSVNDLIMVVAFAP
ITALLLGVSDIQVPWATLLSSVGLYVVLPLIAGVITRYMLQKKGDDSQVNAFVAKLKPWSMVGLLATVVLLFGFQAETII
AEPQNIALIAIPLLIQTYGIFFIAFYAAKKMKLTHKVAAPACMIATSNFFELAVAVAISLFGLHSGAALATVVGVLVEVP
VMLSLVAIVNRSRHLFAEDAVTQS

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=322, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 37353; Mature: 37222

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIFERYLSVWVGLAILAGVFLGNLAPDTFTVIAGLEYAHVNFVIAVLIWVMIYPMMVQI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
DFSAVKDVGKSPKGLVLTLVINWLIKPFTMAALGWLFFKVFFVDFVDPQTASEYIAGMIL
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LGVAPCTAMVFVWSQLTKGDPNYTLVQVSVNDLIMVVAFAPITALLLGVSDIQVPWATLL
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SSVGLYVVLPLIAGVITRYMLQKKGDDSQVNAFVAKLKPWSMVGLLATVVLLFGFQAETI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEE
IAEPQNIALIAIPLLIQTYGIFFIAFYAAKKMKLTHKVAAPACMIATSNFFELAVAVAIS
EECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHH
LFGLHSGAALATVVGVLVEVPVMLSLVAIVNRSRHLFAEDAVTQS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure 
GIFERYLSVWVGLAILAGVFLGNLAPDTFTVIAGLEYAHVNFVIAVLIWVMIYPMMVQI
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
DFSAVKDVGKSPKGLVLTLVINWLIKPFTMAALGWLFFKVFFVDFVDPQTASEYIAGMIL
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LGVAPCTAMVFVWSQLTKGDPNYTLVQVSVNDLIMVVAFAPITALLLGVSDIQVPWATLL
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SSVGLYVVLPLIAGVITRYMLQKKGDDSQVNAFVAKLKPWSMVGLLATVVLLFGFQAETI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEE
IAEPQNIALIAIPLLIQTYGIFFIAFYAAKKMKLTHKVAAPACMIATSNFFELAVAVAIS
EECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHHH
LFGLHSGAALATVVGVLVEVPVMLSLVAIVNRSRHLFAEDAVTQS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]