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The map label for this gene is yciR [C]

Identifier: 157963461

GI number: 157963461

Start: 4437204

End: 4439573

Strand: Reverse

Name: yciR [C]

Synonym: Spea_3649

Alternate gene names: 157963461

Gene position: 4439573-4437204 (Counterclockwise)

Preceding gene: 157963462

Following gene: 157963459

Centisome position: 85.8

GC content: 44.73

Gene sequence:

>2370_bases
ATGCTCACAAGTAACATGAAACACTTTAAATGGTTTAACAGCAAAACCGCGATCATCATTGCTGGCATCTTATTGAGCGG
CTACTTAATTCTTATTTTGACTGTGACCAATTTAGGCCAGAGTCGCTTAAAAGAGTCACAAAATAGCGAGCTTAATTTAA
GAGTCAGTAATTACACCGAAAACTTAAGTTTCTTCTTCGATGCCAGTGAAAAAAATATTGCCAACCTGAGTCAGAAGCGT
GACGTTAATACCTATTTCTCAAATTTAGCGGCAGGTATGTCGCTGCAGTATGGACTCGGTTCGAGTCTATTTAGTCTTAC
TCAGATGATAGAAAACTTTACCCGATCAAACATGATGGATGGTCAGCAGATCTACACAAGAGTGATGATTGTCGGGATAG
GGCAAACCGTTATTGTTAATACTCGACCAGAGGTGGCGTTTGATATTAACCAGCTCCCCCTGAAAGAGATGGAAACAAAA
GACCATAAACTTCAGGTAGTTAAAGGCGTAGAAGGGACCGCCATTCAGTTACTGCAGACGATTTATCATCAGAATAAACC
CGTTGCGATTCTAGTTGCCACCCTAAATACCGATCTGCTGATTAAACTTCTCTCGACGCAGGAGCATCTCGAGAGCGGCA
GCTGCTTGACCTTGGTAACCCCCATCGGAGACATACTGGTTTGGAATTCATTGCAAGGTTGTGAAACTGAAACTGAAATT
GGTAAGACTAGCTATTACGGCGATAATTCTAGGATCATCTATTTTGAGAAAAAGGTCGCGTCGACGCCGCTGGTGCTGGA
GAGTTGGTTTAAGCCCGTTAGTGAGCAAGATATTTTCACCTCTGCGTGGTTTATAGCGGGGATCTCTCTTCTGGCGTTGC
CAGTATTTCTGGGTTTGATCTACCTGATGCGAGTGAATAACGCCAACTTAGTGCTACAGACTCAGGTGGAGTTATCTTCA
GAACAACAACAAAAACTGGCGATGCAAAACACTCAGCTGCATGAAGAGATTTCTAAGCGTAAGGAGTCTGAAAGTAAGCT
GGAATATCAGGCGACTCATGATGAATTAACCAACTTAGCCAATCGCACCCATGGCATGGCTCGCTTGCAGGAGATGATTG
GTCGTTCCCATGTGAAACAGACCCAAATTCTGTTGCTGTTTATCGATCTAGATAACTTTAAGCAGGTTAATGATACCGTG
GGCCATCACGCTGGCGATCTGCTATTAAAGCAAGCCAGTAAGCGCCTACTAAAGTCTGTGCGTACCAGTGATATTGTCGC
TCGCTTAGGTGGTGATGAGTTCTTGGTGATTGTGCCAGATATCCAGCATCAAGACTCTGCCAAGTTGGTAGCGAGTAGTA
TTTTATCTGTGTTTGAAAAGCCATTTCGAATTGAGCAGCAAGAATTTTTTGTCTCGGCCAGTATCGGTATGTCTGTTTAC
CCTAAAGATGGTACCAATGCTTCGACTCTGCTGAAACGCGCCGACACCGCGCTATACAGCGTTAAAGATATGGGCAGGAA
CGGTTTTAACTTTTACGATGAGCAGATGAACCTAGATGTGCAGCGTAGTTTTGCCCTCAATGTACGTTTACATCAGGCCG
TGCAGCAAGGCGAATTAGAGATCTACTATCAACCGATCTTAGATCTGGTTAGTCGTAAGATCGTCGCTGCCGAAGCCCTT
ATGCGCTGGACCGATAGCGAGCTTGGTTTTGTTTCTCCAGAGGATTTCATTCCTTTGGCTGAGAAAAATGGCTTGATCCA
CCGACTCGGCGACATCGTCTTACTTGAGGCTTGTACTCAAGCTGCAGCTTGGCAGCAGATCAGCCCGATCAAGATCGCCA
TCAATTTCTCGAGTGTACAATTTAGGTATTGTGAGGCGTTGCAAGAGCGTATCGTCGATGTGTTGGTGCAAACGGGGCTT
CCTGCTAGCCAGCTGGAAATGGAGGTGACCGAGAGTCTACTGATAGAGCAAGATAATGCCTTGATGAAGATGCTCGCTTA
TCTTAAGCAGCTCGGAGTAGGCCTATCTATCGATGATTTCGGTACCGGTTATTCGGCGTTAAGTTATCTGCAGAAATTCT
CATTTACTAAGCTAAAAATTGATCGCGCCTTTATTAATAATATGACCGTTTGTTCATCGGATGCATCCTTGGTATCGGCG
ATACTGGCGATGGCTAAATCGTTAAAGCTTAAGGTGGTTGCTGAGGGAATTGAAAACGATGAGCAAGCGCTGTTTTTACA
GCAGCACAATTGTGAATTTGGTCAGGGCTATCTGTTTAGTCGTCCTGTGCCGGCTGCAGAGTTTACTCAGCTATTAATTC
GCGACCAGAATGAGGCCAGTTTTACAGAACAAATAGAACGAGCTGGTTAG

Upstream 100 bases:

>100_bases
AAGCAGATCCGCGCGGATGGTAGCTATAACAAGTTAGTGAAAAAGCATTACCCGACCGTTTTTCATTATTATCAAGATTA
TTTTGAACAAGCGGCAGCCG

Downstream 100 bases:

>100_bases
TGATATTTGTAAGCATTTTTGCTCGATTTCAAGATAAAAAAACGGCCCAGGTTGTTATTTAAATCATAACAACTGGGCCG
TTTCTATTGGTGCTTATTTT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 789

Protein sequence:

>789_residues
MLTSNMKHFKWFNSKTAIIIAGILLSGYLILILTVTNLGQSRLKESQNSELNLRVSNYTENLSFFFDASEKNIANLSQKR
DVNTYFSNLAAGMSLQYGLGSSLFSLTQMIENFTRSNMMDGQQIYTRVMIVGIGQTVIVNTRPEVAFDINQLPLKEMETK
DHKLQVVKGVEGTAIQLLQTIYHQNKPVAILVATLNTDLLIKLLSTQEHLESGSCLTLVTPIGDILVWNSLQGCETETEI
GKTSYYGDNSRIIYFEKKVASTPLVLESWFKPVSEQDIFTSAWFIAGISLLALPVFLGLIYLMRVNNANLVLQTQVELSS
EQQQKLAMQNTQLHEEISKRKESESKLEYQATHDELTNLANRTHGMARLQEMIGRSHVKQTQILLLFIDLDNFKQVNDTV
GHHAGDLLLKQASKRLLKSVRTSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFRIEQQEFFVSASIGMSVY
PKDGTNASTLLKRADTALYSVKDMGRNGFNFYDEQMNLDVQRSFALNVRLHQAVQQGELEIYYQPILDLVSRKIVAAEAL
MRWTDSELGFVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAAAWQQISPIKIAINFSSVQFRYCEALQERIVDVLVQTGL
PASQLEMEVTESLLIEQDNALMKMLAYLKQLGVGLSIDDFGTGYSALSYLQKFSFTKLKIDRAFINNMTVCSSDASLVSA
ILAMAKSLKLKVVAEGIENDEQALFLQQHNCEFGQGYLFSRPVPAAEFTQLLIRDQNEASFTEQIERAG

Sequences:

>Translated_789_residues
MLTSNMKHFKWFNSKTAIIIAGILLSGYLILILTVTNLGQSRLKESQNSELNLRVSNYTENLSFFFDASEKNIANLSQKR
DVNTYFSNLAAGMSLQYGLGSSLFSLTQMIENFTRSNMMDGQQIYTRVMIVGIGQTVIVNTRPEVAFDINQLPLKEMETK
DHKLQVVKGVEGTAIQLLQTIYHQNKPVAILVATLNTDLLIKLLSTQEHLESGSCLTLVTPIGDILVWNSLQGCETETEI
GKTSYYGDNSRIIYFEKKVASTPLVLESWFKPVSEQDIFTSAWFIAGISLLALPVFLGLIYLMRVNNANLVLQTQVELSS
EQQQKLAMQNTQLHEEISKRKESESKLEYQATHDELTNLANRTHGMARLQEMIGRSHVKQTQILLLFIDLDNFKQVNDTV
GHHAGDLLLKQASKRLLKSVRTSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFRIEQQEFFVSASIGMSVY
PKDGTNASTLLKRADTALYSVKDMGRNGFNFYDEQMNLDVQRSFALNVRLHQAVQQGELEIYYQPILDLVSRKIVAAEAL
MRWTDSELGFVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAAAWQQISPIKIAINFSSVQFRYCEALQERIVDVLVQTGL
PASQLEMEVTESLLIEQDNALMKMLAYLKQLGVGLSIDDFGTGYSALSYLQKFSFTKLKIDRAFINNMTVCSSDASLVSA
ILAMAKSLKLKVVAEGIENDEQALFLQQHNCEFGQGYLFSRPVPAAEFTQLLIRDQNEASFTEQIERAG
>Mature_789_residues
MLTSNMKHFKWFNSKTAIIIAGILLSGYLILILTVTNLGQSRLKESQNSELNLRVSNYTENLSFFFDASEKNIANLSQKR
DVNTYFSNLAAGMSLQYGLGSSLFSLTQMIENFTRSNMMDGQQIYTRVMIVGIGQTVIVNTRPEVAFDINQLPLKEMETK
DHKLQVVKGVEGTAIQLLQTIYHQNKPVAILVATLNTDLLIKLLSTQEHLESGSCLTLVTPIGDILVWNSLQGCETETEI
GKTSYYGDNSRIIYFEKKVASTPLVLESWFKPVSEQDIFTSAWFIAGISLLALPVFLGLIYLMRVNNANLVLQTQVELSS
EQQQKLAMQNTQLHEEISKRKESESKLEYQATHDELTNLANRTHGMARLQEMIGRSHVKQTQILLLFIDLDNFKQVNDTV
GHHAGDLLLKQASKRLLKSVRTSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFRIEQQEFFVSASIGMSVY
PKDGTNASTLLKRADTALYSVKDMGRNGFNFYDEQMNLDVQRSFALNVRLHQAVQQGELEIYYQPILDLVSRKIVAAEAL
MRWTDSELGFVSPEDFIPLAEKNGLIHRLGDIVLLEACTQAAAWQQISPIKIAINFSSVQFRYCEALQERIVDVLVQTGL
PASQLEMEVTESLLIEQDNALMKMLAYLKQLGVGLSIDDFGTGYSALSYLQKFSFTKLKIDRAFINNMTVCSSDASLVSA
ILAMAKSLKLKVVAEGIENDEQALFLQQHNCEFGQGYLFSRPVPAAEFTQLLIRDQNEASFTEQIERAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=442, Percent_Identity=34.3891402714932, Blast_Score=276, Evalue=5e-75,
Organism=Escherichia coli, GI87081921, Length=434, Percent_Identity=32.4884792626728, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI226510982, Length=428, Percent_Identity=28.7383177570093, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=34.4398340248963, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=33.0612244897959, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=244, Percent_Identity=34.4262295081967, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1787055, Length=288, Percent_Identity=30.5555555555556, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=31.2741312741313, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=32.6612903225806, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=36.2637362637363, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=29.8319327731092, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788849, Length=266, Percent_Identity=30.8270676691729, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=34.9693251533742, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=34.3373493975904, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=27.6859504132231, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=30.1136363636364, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI87081977, Length=171, Percent_Identity=32.1637426900585, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693134, Length=178, Percent_Identity=32.0224719101124, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=34.7560975609756, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787410, Length=219, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=30.0613496932515, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=151, Percent_Identity=32.4503311258278, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787816, Length=135, Percent_Identity=30.3703703703704, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 88498; Mature: 88498

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSNMKHFKWFNSKTAIIIAGILLSGYLILILTVTNLGQSRLKESQNSELNLRVSNYTE
CCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCCC
NLSFFFDASEKNIANLSQKRDVNTYFSNLAAGMSLQYGLGSSLFSLTQMIENFTRSNMMD
CEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHCCCC
GQQIYTRVMIVGIGQTVIVNTRPEVAFDINQLPLKEMETKDHKLQVVKGVEGTAIQLLQT
HHHHHHEEHEEECCCEEEEECCCCEEEECCCCCHHHHCCCCCCEEEEECCCHHHHHHHHH
IYHQNKPVAILVATLNTDLLIKLLSTQEHLESGSCLTLVTPIGDILVWNSLQGCETETEI
HHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHEECCCCCCCCHHHC
GKTSYYGDNSRIIYFEKKVASTPLVLESWFKPVSEQDIFTSAWFIAGISLLALPVFLGLI
CCCEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YLMRVNNANLVLQTQVELSSEQQQKLAMQNTQLHEEISKRKESESKLEYQATHDELTNLA
HHHEECCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRTHGMARLQEMIGRSHVKQTQILLLFIDLDNFKQVNDTVGHHAGDLLLKQASKRLLKSV
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFRIEQQEFFVSASIGMSVY
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCEEE
PKDGTNASTLLKRADTALYSVKDMGRNGFNFYDEQMNLDVQRSFALNVRLHQAVQQGELE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEHHEEEHHHHHHHHHCCCEE
IYYQPILDLVSRKIVAAEALMRWTDSELGFVSPEDFIPLAEKNGLIHRLGDIVLLEACTQ
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHCCCHHHHHHHHHHHHHHHH
AAAWQQISPIKIAINFSSVQFRYCEALQERIVDVLVQTGLPASQLEMEVTESLLIEQDNA
HHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
LMKMLAYLKQLGVGLSIDDFGTGYSALSYLQKFSFTKLKIDRAFINNMTVCSSDASLVSA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHEEEHHHHHCCCEEECCCHHHHHH
ILAMAKSLKLKVVAEGIENDEQALFLQQHNCEFGQGYLFSRPVPAAEFTQLLIRDQNEAS
HHHHHHHCEEEEEECCCCCCCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCHH
FTEQIERAG
HHHHHHHCC
>Mature Secondary Structure
MLTSNMKHFKWFNSKTAIIIAGILLSGYLILILTVTNLGQSRLKESQNSELNLRVSNYTE
CCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCCC
NLSFFFDASEKNIANLSQKRDVNTYFSNLAAGMSLQYGLGSSLFSLTQMIENFTRSNMMD
CEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHCCCC
GQQIYTRVMIVGIGQTVIVNTRPEVAFDINQLPLKEMETKDHKLQVVKGVEGTAIQLLQT
HHHHHHEEHEEECCCEEEEECCCCEEEECCCCCHHHHCCCCCCEEEEECCCHHHHHHHHH
IYHQNKPVAILVATLNTDLLIKLLSTQEHLESGSCLTLVTPIGDILVWNSLQGCETETEI
HHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHEECCCCCCCCHHHC
GKTSYYGDNSRIIYFEKKVASTPLVLESWFKPVSEQDIFTSAWFIAGISLLALPVFLGLI
CCCEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YLMRVNNANLVLQTQVELSSEQQQKLAMQNTQLHEEISKRKESESKLEYQATHDELTNLA
HHHEECCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRTHGMARLQEMIGRSHVKQTQILLLFIDLDNFKQVNDTVGHHAGDLLLKQASKRLLKSV
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTSDIVARLGGDEFLVIVPDIQHQDSAKLVASSILSVFEKPFRIEQQEFFVSASIGMSVY
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCEEE
PKDGTNASTLLKRADTALYSVKDMGRNGFNFYDEQMNLDVQRSFALNVRLHQAVQQGELE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEHHEEEHHHHHHHHHCCCEE
IYYQPILDLVSRKIVAAEALMRWTDSELGFVSPEDFIPLAEKNGLIHRLGDIVLLEACTQ
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHCCCHHHHHHHHHHHHHHHH
AAAWQQISPIKIAINFSSVQFRYCEALQERIVDVLVQTGLPASQLEMEVTESLLIEQDNA
HHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHH
LMKMLAYLKQLGVGLSIDDFGTGYSALSYLQKFSFTKLKIDRAFINNMTVCSSDASLVSA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHEEEHHHHHCCCEEECCCHHHHHH
ILAMAKSLKLKVVAEGIENDEQALFLQQHNCEFGQGYLFSRPVPAAEFTQLLIRDQNEAS
HHHHHHHCEEEEEECCCCCCCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCHH
FTEQIERAG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]