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The map label for this gene is mlaC [H]

Identifier: 157963420

GI number: 157963420

Start: 4399566

End: 4400237

Strand: Reverse

Name: mlaC [H]

Synonym: Spea_3606

Alternate gene names: 157963420

Gene position: 4400237-4399566 (Counterclockwise)

Preceding gene: 157963421

Following gene: 157963419

Centisome position: 85.04

GC content: 41.96

Gene sequence:

>672_bases
ATGTTTAAAGGTTTTTATCGAAGTGCGATGTTAGTCATTATGGCGCTGCTTAGTGTTAGTTTGAGTGTTAGTGCTCATGC
AGAGGTAAGTACCGATATCGATCAAACCAACCCTTTTACCTTGGTTGAGGCTGTTGCTAACAAGACCTTTGCGCGTTTTC
ATCAAGATGAGAAGCTCATCGCGGAGAACCCCGATCATTTAAAAATTATCGTGACAGAAGAGTTGATGCCTTATGTTGAT
TATAAGTACGCTTCTTATAAGGTATTAGGTCAATATCTACGTGATACCACTAAAGATCAGCGTGACCGTTTTGTTGAAGC
GTTTAGGGGCTATCTCATCTCGACTTATGCCCAAGCATTTACGGAATATACCGACCAAAAGGTACAATATGCCAAGGCGG
TAGACTTTGCTGGCGAGAAGTTCGTTAACGTTGATGTGCAGATCATCGAGCAGGGACGTCCTGCGATCAAGTTGCAGTTT
AAGGCGCGTCGTTTAAAAAATGGCAATTGGAAAGCATTTGACTTAATTGCCGAAGGCGTTAGCTTGTTATCATCTAAGCA
GTCTGAAATCACTAACCTTGTACGTCAACAAGGTATCGAGTCTGTGATTACTATGCTCAATGAGCGCACAAATCAACATA
TCGATTTAGACGCGAATGAGAAAAAGAGCTAG

Upstream 100 bases:

>100_bases
CCCATTCGGCGCTAGTGTTAGAAGACTTGATTGGCCAGTTCCTGTATAGCACGGGATCAAAGGACTAACCTCTTAAGATA
AGTTGTTGGAGTATTTCAAA

Downstream 100 bases:

>100_bases
TGGTTTCATTTAATCAGCAAGGGATTAATTGCACCGTATCTGGATGTTTAGACCAAGAGGCGGTGCGCAGTCTATGGAAT
GGACGCAGTAGTATTTTAGA

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MFKGFYRSAMLVIMALLSVSLSVSAHAEVSTDIDQTNPFTLVEAVANKTFARFHQDEKLIAENPDHLKIIVTEELMPYVD
YKYASYKVLGQYLRDTTKDQRDRFVEAFRGYLISTYAQAFTEYTDQKVQYAKAVDFAGEKFVNVDVQIIEQGRPAIKLQF
KARRLKNGNWKAFDLIAEGVSLLSSKQSEITNLVRQQGIESVITMLNERTNQHIDLDANEKKS

Sequences:

>Translated_223_residues
MFKGFYRSAMLVIMALLSVSLSVSAHAEVSTDIDQTNPFTLVEAVANKTFARFHQDEKLIAENPDHLKIIVTEELMPYVD
YKYASYKVLGQYLRDTTKDQRDRFVEAFRGYLISTYAQAFTEYTDQKVQYAKAVDFAGEKFVNVDVQIIEQGRPAIKLQF
KARRLKNGNWKAFDLIAEGVSLLSSKQSEITNLVRQQGIESVITMLNERTNQHIDLDANEKKS
>Mature_223_residues
MFKGFYRSAMLVIMALLSVSLSVSAHAEVSTDIDQTNPFTLVEAVANKTFARFHQDEKLIAENPDHLKIIVTEELMPYVD
YKYASYKVLGQYLRDTTKDQRDRFVEAFRGYLISTYAQAFTEYTDQKVQYAKAVDFAGEKFVNVDVQIIEQGRPAIKLQF
KARRLKNGNWKAFDLIAEGVSLLSSKQSEITNLVRQQGIESVITMLNERTNQHIDLDANEKKS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=209, Percent_Identity=41.6267942583732, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 25505; Mature: 25505

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGFYRSAMLVIMALLSVSLSVSAHAEVSTDIDQTNPFTLVEAVANKTFARFHQDEKLI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
AENPDHLKIIVTEELMPYVDYKYASYKVLGQYLRDTTKDQRDRFVEAFRGYLISTYAQAF
CCCCCCEEEEEECHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TEYTDQKVQYAKAVDFAGEKFVNVDVQIIEQGRPAIKLQFKARRLKNGNWKAFDLIAEGV
HHHHHHHHHHHHHHHHCCCCEEECHHEEEECCCCEEEEEEEHHHHCCCCCHHHHHHHHHH
SLLSSKQSEITNLVRQQGIESVITMLNERTNQHIDLDANEKKS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MFKGFYRSAMLVIMALLSVSLSVSAHAEVSTDIDQTNPFTLVEAVANKTFARFHQDEKLI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
AENPDHLKIIVTEELMPYVDYKYASYKVLGQYLRDTTKDQRDRFVEAFRGYLISTYAQAF
CCCCCCEEEEEECHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TEYTDQKVQYAKAVDFAGEKFVNVDVQIIEQGRPAIKLQFKARRLKNGNWKAFDLIAEGV
HHHHHHHHHHHHHHHHCCCCEEECHHEEEECCCCEEEEEEEHHHHCCCCCHHHHHHHHHH
SLLSSKQSEITNLVRQQGIESVITMLNERTNQHIDLDANEKKS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]