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The map label for this gene is argD [H]

Identifier: 157963330

GI number: 157963330

Start: 4296183

End: 4297400

Strand: Reverse

Name: argD [H]

Synonym: Spea_3516

Alternate gene names: 157963330

Gene position: 4297400-4296183 (Counterclockwise)

Preceding gene: 157963331

Following gene: 157963329

Centisome position: 83.05

GC content: 47.62

Gene sequence:

>1218_bases
ATGAGCTCAAAAATGAATCTTACACGTGCCCAATTTGACGAAGTTATGGTGCCTAACTATGCGCCTTCTGCAGTAATTCC
TGTTCGTGGCGAAGGTAGCCGAGTTTGGGATCAAGAAGGTAAAGAGTATATCGACTTTGCTGGTGGTATCGCGGTTAACT
GTTTAGGTCATTGTCATCCAGCCTTAGTTGGCGCGCTAAAGACCCAAGGCGAAAAGCTTTGGCATCTTGCTAACGTAATG
ACCAACGAGCCAGCGCTTGAGCTAGCGACTAAGCTTGTCGATGCCACATTTGCCGACCGCGTCTATTTTGCTAACTCAGG
TGCAGAAGCAAACGAAGCGGCACTTAAACTAGTACGCCGTTATGCAATGGATAAATTTGGCGTTGAAAAAGATCAAATCA
TCGCATTTGATAAAGCCTTCCATGGTCGTACTTTCTTTACTGTGAGTGTGGGTGGCCAAGCCGCTTATTCTGACGGTTTC
GGTCCTAAGCCACAGAGCATTACTCATGTTCCGTTCAATGATATCGCAGCCCTAGAAGCCGTCTTCTCTGATAAGACTTG
TGCAGTCATGATGGAGCCGCTTCAAGGCGAAGGCGGTATTATCGATGCTGATCCAGAGTTTTTAAAGGCGGTTCGTGCCC
TTTGTGATAAGCACAATGCATTATTGGTATTCGATGAAGTACAAACCGGTGTGGGTCGTCTAGGCGAGCTTTACGCTTAC
ATGCGTGGTGATGTAGTGCCTGATGTATTAACAACGGCAAAAGCGTTAGGTGGCGGCTTCCCGATAGCAGCTATGCTAAC
AACAAAAGAGATTGCCGATCATCTAAAGATAGGTACTCACGGTTCTACCTACGGCGGCAACCCTCTAGCTTGTGCCGTAG
GTAATGCGGTACTGGATGTGGTTAACACGCCAGAAGTATTGAACGGTGTTAAGCTGCGCGAGCAGTTATTGCGTGATGGT
TTAATTGCGATCAACGCAAAGTATGATGTGTTCTCTGAAATCCGTGGCCAAGGTCTGTTGTTAGGTGCGGTCATGAATGA
AAGATTCCAGGGTCGTGCTAAAGAGTTCTTAGTAGCCGCTATTAACGAAGGCGTAATGAGCCTAGTTGCGGGTGCAAACG
TAGTTCGCTTCACGCCATCTCTAGTGATCCCAGAAGCGGATATTGCCGAAGGTCTAGCGCGTTTTGAGCGTGCAGTCGCT
AAAGTTGTCGAAGCCTAA

Upstream 100 bases:

>100_bases
CCATGTTACACAAGCAATCGCCGTGTCACCTACACAAGATAAAGACACCGGGCGGAAAACGACCAGCTAAAAGGTCGATA
ATTATGAAGGATGAGAAGCA

Downstream 100 bases:

>100_bases
AGGCCAAACGGAGTGTTATCAATGATAGCGCTCCTTTTTTTGTCTTTAGGATAACTTGAACGTTTATTGACCAGTGCTTG
TCATATATTGATAAGACTGA

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSSKMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHPALVGALKTQGEKLWHLANVM
TNEPALELATKLVDATFADRVYFANSGAEANEAALKLVRRYAMDKFGVEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPQSITHVPFNDIAALEAVFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIADHLKIGTHGSTYGGNPLACAVGNAVLDVVNTPEVLNGVKLREQLLRDG
LIAINAKYDVFSEIRGQGLLLGAVMNERFQGRAKEFLVAAINEGVMSLVAGANVVRFTPSLVIPEADIAEGLARFERAVA
KVVEA

Sequences:

>Translated_405_residues
MSSKMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHPALVGALKTQGEKLWHLANVM
TNEPALELATKLVDATFADRVYFANSGAEANEAALKLVRRYAMDKFGVEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPQSITHVPFNDIAALEAVFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIADHLKIGTHGSTYGGNPLACAVGNAVLDVVNTPEVLNGVKLREQLLRDG
LIAINAKYDVFSEIRGQGLLLGAVMNERFQGRAKEFLVAAINEGVMSLVAGANVVRFTPSLVIPEADIAEGLARFERAVA
KVVEA
>Mature_404_residues
SSKMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHPALVGALKTQGEKLWHLANVMT
NEPALELATKLVDATFADRVYFANSGAEANEAALKLVRRYAMDKFGVEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFG
PKPQSITHVPFNDIAALEAVFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAYM
RGDVVPDVLTTAKALGGGFPIAAMLTTKEIADHLKIGTHGSTYGGNPLACAVGNAVLDVVNTPEVLNGVKLREQLLRDGL
IAINAKYDVFSEIRGQGLLLGAVMNERFQGRAKEFLVAAINEGVMSLVAGANVVRFTPSLVIPEADIAEGLARFERAVAK
VVEA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=34.8051948051948, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.1170568561873, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=29.1954022988506, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=27.5943396226415, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=28.0205655526992, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=26.4150943396226, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI24119277, Length=391, Percent_Identity=27.8772378516624, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI188536080, Length=416, Percent_Identity=23.5576923076923, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38679950, Length=416, Percent_Identity=23.5576923076923, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38679946, Length=416, Percent_Identity=23.5576923076923, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=64.1604010025063, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=59.9496221662469, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1789016, Length=392, Percent_Identity=36.2244897959184, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=34.0050377833753, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI145693181, Length=374, Percent_Identity=34.4919786096257, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786991, Length=327, Percent_Identity=34.2507645259939, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786349, Length=308, Percent_Identity=30.8441558441558, Blast_Score=128, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=35.1063829787234, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=30.3854875283447, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=265, Percent_Identity=33.9622641509434, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=26.8965517241379, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=414, Percent_Identity=24.1545893719807, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=37.8787878787879, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=32.8358208955224, Blast_Score=212, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=340, Percent_Identity=28.8235294117647, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21357415, Length=401, Percent_Identity=35.1620947630923, Blast_Score=232, Evalue=3e-61,
Organism=Drosophila melanogaster, GI28574759, Length=413, Percent_Identity=31.9612590799031, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI161085790, Length=424, Percent_Identity=31.3679245283019, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=27.8688524590164, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281366494, Length=429, Percent_Identity=22.8438228438228, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667139, Length=429, Percent_Identity=22.8438228438228, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667143, Length=429, Percent_Identity=22.8438228438228, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43387; Mature: 43256

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHP
CCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHHHHH
ALVGALKTQGEKLWHLANVMTNEPALELATKLVDATFADRVYFANSGAEANEAALKLVRR
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
YAMDKFGVEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHVPFNDIAALEA
HHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCHHHHHHHH
VFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
HHCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIADHLKIGTHGSTYGGNPLACAVGNAVLDV
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEHHHHHHHH
VNTPEVLNGVKLREQLLRDGLIAINAKYDVFSEIRGQGLLLGAVMNERFQGRAKEFLVAA
CCCHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
INEGVMSLVAGANVVRFTPSLVIPEADIAEGLARFERAVAKVVEA
HHHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSKMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHP
CCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHHHHH
ALVGALKTQGEKLWHLANVMTNEPALELATKLVDATFADRVYFANSGAEANEAALKLVRR
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
YAMDKFGVEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHVPFNDIAALEA
HHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCHHHHHHHH
VFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
HHCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIADHLKIGTHGSTYGGNPLACAVGNAVLDV
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEHHHHHHHH
VNTPEVLNGVKLREQLLRDGLIAINAKYDVFSEIRGQGLLLGAVMNERFQGRAKEFLVAA
CCCHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
INEGVMSLVAGANVVRFTPSLVIPEADIAEGLARFERAVAKVVEA
HHHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]