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The map label for this gene is ndh [H]

Identifier: 157963228

GI number: 157963228

Start: 4173340

End: 4174641

Strand: Reverse

Name: ndh [H]

Synonym: Spea_3414

Alternate gene names: 157963228

Gene position: 4174641-4173340 (Counterclockwise)

Preceding gene: 157963231

Following gene: 157963225

Centisome position: 80.68

GC content: 46.31

Gene sequence:

>1302_bases
ATGAGATCGGCAAACCCAAAGATTGTGATTGTTGGTGGTGGCGCAGGTGGTTTGGAGTTAGCGACTCAGCTGGGTCATAA
GTTAGGTAAGAAAAACTTAGCTCAAATCATCTTAGTCGATAGAAACCGGACTCACATTTGGAAACCATTACTGCATGAGG
TGGCTACAGGTTCTCTTGACTCTGCACTTGATGGGGTTGTGTACTCTGCTCATGCCGCTAAGCACGGTTACCAATTTCAG
CTTGGTACTTTCTGTGGTTTAGATGAAGCGAGTCAGTCGATTTCAGTCGCTCCTATCGTAGATGAAGCGGGTAAAGTAAT
GCTGCCTGAGCGCCAAATTCAATATGATAAGTTAGTGATTGCTATTGGTAGCGTCAGTAATGACTTTAATACTCCTGGTG
TCAAAGAAAACTGTTTCTTCCTCGACTCGCACCAGCAAGCCAATCGTTTCCATAATGCGCTTTTAGATAGTTTTACTCGG
GTGCATCAATCAGAAAGTATCAATGAGCTTAATATCGCCATTGTTGGCGGTGGCGCAACGGGTGTTGAATTGTCGGCAGA
GCTCTACCATGTGACCGACATGCTTAAAGTTTATGGCTTAAGTAAGATGACCGCCGATAAGCTTAATATTCATTTGATTG
AAGCGGGTGAGCGAATTCTTCCAGCGCTACCAGAGCGCATTGCGACGTCTGCAAGAGTTGAGCTGAGCAAGCTTGGCGTC
AATGTGATGGAAAACACCCGTATTAGCGAGGCGACAGCAGCAGGTTTTGTTACCTCTGAAGGCCAGTTGATAGAAGCCAA
TATTATGCTTTGGGCTGCAGGGGTTAAGGCGCCTGACTTTATTAAGGATATCGGTTTATTTGAGCTTAACCGCGCTAATC
AAATTATGGTTAAACCTAACCTGCTCAGCACCGTAAGTAATGATATTTACGTGATAGGTGACTGTTGTGCCTGCATGCAA
GCCGATGGCAGCTTTGTGCCGCCGCGGGCGCAGTCAGCGCATCAGATGGCACAGTGTGTTGAGAAGAACATCTTTAACGA
GCTAAAAGGTGAGCCGCTGAACGATTATATGTATGTCGATCATGGTTCGTTAGTGAACCTATCGCGTTACAGCACTGTGG
GTAGTTTGATGGGTAACCTGACAAAAAGCAGCATGTTTGTTGAGGGGAAGATCGCGCGTTTAGTGTATATCTCGCTTTAC
CGTATGCATCAGCAAGCGATTCACGGCACTTTTAAAACGGTGGCTTTGTGGTGCGCTGAAAAGGTGATGCGCGTGGTGCG
TCCAAGAATGAAGCTGCACTAA

Upstream 100 bases:

>100_bases
AACATAGCGAGTATTAAGTAAGTGGTCGTTAAATTAGTATTTTACCATGTTGAAGCCTAATTGGGTCTTCAGCAGTTGGC
CTAGATAGAGGAACGAAGTA

Downstream 100 bases:

>100_bases
TATTTACAAGTGGTACTAATATTTAGAGGCTGCACTTATATTTAGAGATTGAATTAGCATTTACAAGCTCAAATAATAAA
AGGGAAGTTATTCCCTTTTA

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDRNRTHIWKPLLHEVATGSLDSALDGVVYSAHAAKHGYQFQ
LGTFCGLDEASQSISVAPIVDEAGKVMLPERQIQYDKLVIAIGSVSNDFNTPGVKENCFFLDSHQQANRFHNALLDSFTR
VHQSESINELNIAIVGGGATGVELSAELYHVTDMLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARVELSKLGV
NVMENTRISEATAAGFVTSEGQLIEANIMLWAAGVKAPDFIKDIGLFELNRANQIMVKPNLLSTVSNDIYVIGDCCACMQ
ADGSFVPPRAQSAHQMAQCVEKNIFNELKGEPLNDYMYVDHGSLVNLSRYSTVGSLMGNLTKSSMFVEGKIARLVYISLY
RMHQQAIHGTFKTVALWCAEKVMRVVRPRMKLH

Sequences:

>Translated_433_residues
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDRNRTHIWKPLLHEVATGSLDSALDGVVYSAHAAKHGYQFQ
LGTFCGLDEASQSISVAPIVDEAGKVMLPERQIQYDKLVIAIGSVSNDFNTPGVKENCFFLDSHQQANRFHNALLDSFTR
VHQSESINELNIAIVGGGATGVELSAELYHVTDMLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARVELSKLGV
NVMENTRISEATAAGFVTSEGQLIEANIMLWAAGVKAPDFIKDIGLFELNRANQIMVKPNLLSTVSNDIYVIGDCCACMQ
ADGSFVPPRAQSAHQMAQCVEKNIFNELKGEPLNDYMYVDHGSLVNLSRYSTVGSLMGNLTKSSMFVEGKIARLVYISLY
RMHQQAIHGTFKTVALWCAEKVMRVVRPRMKLH
>Mature_433_residues
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDRNRTHIWKPLLHEVATGSLDSALDGVVYSAHAAKHGYQFQ
LGTFCGLDEASQSISVAPIVDEAGKVMLPERQIQYDKLVIAIGSVSNDFNTPGVKENCFFLDSHQQANRFHNALLDSFTR
VHQSESINELNIAIVGGGATGVELSAELYHVTDMLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARVELSKLGV
NVMENTRISEATAAGFVTSEGQLIEANIMLWAAGVKAPDFIKDIGLFELNRANQIMVKPNLLSTVSNDIYVIGDCCACMQ
ADGSFVPPRAQSAHQMAQCVEKNIFNELKGEPLNDYMYVDHGSLVNLSRYSTVGSLMGNLTKSSMFVEGKIARLVYISLY
RMHQQAIHGTFKTVALWCAEKVMRVVRPRMKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=434, Percent_Identity=58.7557603686636, Blast_Score=528, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6323515, Length=372, Percent_Identity=23.9247311827957, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320118, Length=364, Percent_Identity=26.6483516483516, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47347; Mature: 47347

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDRNRTHIWKPLLHEVATGSLD
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHH
SALDGVVYSAHAAKHGYQFQLGTFCGLDEASQSISVAPIVDEAGKVMLPERQIQYDKLVI
HHHHHHHEEHHHHCCCCEEEECCCCCCCHHCCCEEEEEECCCCCCEECCHHHCCEEEEEE
AIGSVSNDFNTPGVKENCFFLDSHQQANRFHNALLDSFTRVHQSESINELNIAIVGGGAT
EEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
GVELSAELYHVTDMLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARVELSKLGV
CCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEHHHCCC
NVMENTRISEATAAGFVTSEGQLIEANIMLWAAGVKAPDFIKDIGLFELNRANQIMVKPN
CHHCCCCCCHHHHCCEEECCCCEEEEEEEEEECCCCCCHHHHHCCCEEECCCCEEEECCH
LLSTVSNDIYVIGDCCACMQADGSFVPPRAQSAHQMAQCVEKNIFNELKGEPLNDYMYVD
HHHHHCCCEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
HGSLVNLSRYSTVGSLMGNLTKSSMFVEGKIARLVYISLYRMHQQAIHGTFKTVALWCAE
CCCEEEHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVMRVVRPRMKLH
HHHHHHHHHHCCC
>Mature Secondary Structure
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDRNRTHIWKPLLHEVATGSLD
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHH
SALDGVVYSAHAAKHGYQFQLGTFCGLDEASQSISVAPIVDEAGKVMLPERQIQYDKLVI
HHHHHHHEEHHHHCCCCEEEECCCCCCCHHCCCEEEEEECCCCCCEECCHHHCCEEEEEE
AIGSVSNDFNTPGVKENCFFLDSHQQANRFHNALLDSFTRVHQSESINELNIAIVGGGAT
EEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
GVELSAELYHVTDMLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARVELSKLGV
CCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEEHHHCCC
NVMENTRISEATAAGFVTSEGQLIEANIMLWAAGVKAPDFIKDIGLFELNRANQIMVKPN
CHHCCCCCCHHHHCCEEECCCCEEEEEEEEEECCCCCCHHHHHCCCEEECCCCEEEECCH
LLSTVSNDIYVIGDCCACMQADGSFVPPRAQSAHQMAQCVEKNIFNELKGEPLNDYMYVD
HHHHHCCCEEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
HGSLVNLSRYSTVGSLMGNLTKSSMFVEGKIARLVYISLYRMHQQAIHGTFKTVALWCAE
CCCEEEHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVMRVVRPRMKLH
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]