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The map label for this gene is hxuC [H]

Identifier: 157963143

GI number: 157963143

Start: 4069772

End: 4071838

Strand: Reverse

Name: hxuC [H]

Synonym: Spea_3327

Alternate gene names: 157963143

Gene position: 4071838-4069772 (Counterclockwise)

Preceding gene: 157963150

Following gene: 157963142

Centisome position: 78.69

GC content: 46.44

Gene sequence:

>2067_bases
ATGACTAAGAAGCCTGTTGTAGTCGCTATGGCAATGGCTCTAAGCTCGGGCGCATTTGCTGCGCAAACTCAGCAAGTCTC
TGAGCAGCAAATAACTGAGTTTGATGAAGTGCTTGTCACCGCGACTCGTGTAAGCGAGAAAGCATCGGAAACTAGCCGCA
GCGTGGCAGTCGTTACTGAAGAGCAATTGCAGGAGTCGCAACCTTCATCGGTTGCCCAGGCATTGAAAAATGAAGCTAAC
GTTAATGTGAGCAATGGTCCTCGTGCTTCATCTCAAGGCGTTGAGATCCGTGGTCTTGGTGGCCAGCGAGTGCTGCAAAC
TATTGATGGTGCTCGTCAAAACACAAATTCAGGCCATCGCGGCACCTACTTTATGGATCCTGAGCTTTTAAGTTCGGTCG
AAGTGGTTCGTGGCCCTGCTAGTAGTTTATGGGGCAGCGGGGCGATTGGTGGCGTCGTTGCGCAAAATACCAAGTCGGCA
GCAGACTTTTTAGACGAAGAAGACAGCTTTGGTGGCTACCTTAAGCAAGGTTATGAATCTAACGGCGACCGCATTAAAAC
CAGTGGTGCGATTTACGGCTTAACCCAAACTGATGCAGCTGGCAAGGTAGATTGGTTACTCAATGGTAGCTACTACGACA
GCAACAATATCAAAATTGGTAATGATAAAACGCTAGAGAACAGTGCGTCGCAAGGCACAAGTGGTCTAGCAAAATTTGGC
TGGGAGCCAACGGATGAACAGCGCCTGCAACTGTCTGCACGTTTTTCTGATACTGACGAGTTAGTACCGAGTAACCCAGC
GACTAACGTCGGCACCTCGGTACCTTTAGTTAAGCGTAAAACCCAAGATCAAAACGTGACGTTAGATTACAGCCTAAACC
CGACAGATAACGCCTTACTTGACTTAAATGCCACCCTGTATTGGAACGGTACCGATTACGATGAAGATCGCGTCACTAAA
AACCAATTTGATAGCACTGAATATGAAACTCTAGGTTTTAGTCTTAGTAATAGCTCTACGCTAGGTAATACTGTACTGAC
ATACGGTGTTGATGGTTATCAGGACTCAATTAAAACAGTACGTGATGACAGCGGCCAATTTGGCCAACGTCCAGATGATA
TAGACGGCGACACCACAGTTTGGGGTGCATTTACTCGTGCCGATATTGAGTTAACAGAGACTTGGTCTGTGGACGCTGCT
GTGCGTTACGACGCTTTTGAAAACCAGAGTAACAACCTTAATCAGTCATCGGATGATAGCGCATTTTCCCCTTCAGTTGG
CCTAGTGTGGAAGACCACTGATTGGTTAACTTTGAGCGCACGTTACGATCAAGCATTCCGCGCCCCAAGCATGGAAGAGA
TGTACTCAACAGGTACCCACTACTGTATTCCAGCTATTCCAGGTTTCTTGCCGAACGGCCTATGTAACACCTTTGAGATC
AACCCAGACCTTAAAGCTGAGCAAGCAGAAAACAAAGAAATTAAAGCCGATTTACGTTTTGCCAATCTAGCGGGTAATGA
CGAGCTTGCCATTACGCTTAACGTGTTTAGAAATGACGTAGATGACTTTATCGAGCAATCAGTTTCGAATCCATTAATGG
GCATCCCCGGCTTTGAGCAAACCACCTCTTGGGACAATGTTGATGAAGCTAAACTGACTGGTTTTGAGTTTTCAACTCGC
TACCGTTATGAGCAAACTCGCGTGAGCTTCAACTACGGTCAAACCGAAGGCAAAGACAAGGCTACAGACGAATACTTATC
AAACATTCCCGCTAAGAAGTTAGCGATTGACCTTTCACAAGGGATCATGGAAGGCGATATGAAGGTTGGTACTCGCTTTA
CTTATGTTGCCGAGCAAGATCAGCTACCAGTAGATAACGTAAATCAGTACGACTCTTACAAACTATGGGATATGTATGTG
GCATGGGAGCCAGCCATGGGCACATTTGAAGGTCTACGAGTCGACTTCGCAGTAGAAAACATTGGTGATGAGGAATATCG
CCAAGCGTGGCAAACCTTGTATGAACAAGGCAGGAATTTCAAGTTGTCAGCGCGCTATAACTTCTAA

Upstream 100 bases:

>100_bases
AAAGTGCCGAAAAATAACAAAACGGCAGTCTCGAAATTCTAATCCTAACCAAGTGGATTGCAGATGAGACGCTATTGATA
CTTACCTTGAGGATTGAAAA

Downstream 100 bases:

>100_bases
GTTAAGTTATGCCAATCCGGGGCCGACTCAGAGAATATAAATGAGTTGGCCTCTTTGTCGTTTAGTTAACTAACGCATAG
TTAACAAGCGCTTAGTTAAT

Product: TonB-dependent heme/hemoglobin receptor family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MTKKPVVVAMAMALSSGAFAAQTQQVSEQQITEFDEVLVTATRVSEKASETSRSVAVVTEEQLQESQPSSVAQALKNEAN
VNVSNGPRASSQGVEIRGLGGQRVLQTIDGARQNTNSGHRGTYFMDPELLSSVEVVRGPASSLWGSGAIGGVVAQNTKSA
ADFLDEEDSFGGYLKQGYESNGDRIKTSGAIYGLTQTDAAGKVDWLLNGSYYDSNNIKIGNDKTLENSASQGTSGLAKFG
WEPTDEQRLQLSARFSDTDELVPSNPATNVGTSVPLVKRKTQDQNVTLDYSLNPTDNALLDLNATLYWNGTDYDEDRVTK
NQFDSTEYETLGFSLSNSSTLGNTVLTYGVDGYQDSIKTVRDDSGQFGQRPDDIDGDTTVWGAFTRADIELTETWSVDAA
VRYDAFENQSNNLNQSSDDSAFSPSVGLVWKTTDWLTLSARYDQAFRAPSMEEMYSTGTHYCIPAIPGFLPNGLCNTFEI
NPDLKAEQAENKEIKADLRFANLAGNDELAITLNVFRNDVDDFIEQSVSNPLMGIPGFEQTTSWDNVDEAKLTGFEFSTR
YRYEQTRVSFNYGQTEGKDKATDEYLSNIPAKKLAIDLSQGIMEGDMKVGTRFTYVAEQDQLPVDNVNQYDSYKLWDMYV
AWEPAMGTFEGLRVDFAVENIGDEEYRQAWQTLYEQGRNFKLSARYNF

Sequences:

>Translated_688_residues
MTKKPVVVAMAMALSSGAFAAQTQQVSEQQITEFDEVLVTATRVSEKASETSRSVAVVTEEQLQESQPSSVAQALKNEAN
VNVSNGPRASSQGVEIRGLGGQRVLQTIDGARQNTNSGHRGTYFMDPELLSSVEVVRGPASSLWGSGAIGGVVAQNTKSA
ADFLDEEDSFGGYLKQGYESNGDRIKTSGAIYGLTQTDAAGKVDWLLNGSYYDSNNIKIGNDKTLENSASQGTSGLAKFG
WEPTDEQRLQLSARFSDTDELVPSNPATNVGTSVPLVKRKTQDQNVTLDYSLNPTDNALLDLNATLYWNGTDYDEDRVTK
NQFDSTEYETLGFSLSNSSTLGNTVLTYGVDGYQDSIKTVRDDSGQFGQRPDDIDGDTTVWGAFTRADIELTETWSVDAA
VRYDAFENQSNNLNQSSDDSAFSPSVGLVWKTTDWLTLSARYDQAFRAPSMEEMYSTGTHYCIPAIPGFLPNGLCNTFEI
NPDLKAEQAENKEIKADLRFANLAGNDELAITLNVFRNDVDDFIEQSVSNPLMGIPGFEQTTSWDNVDEAKLTGFEFSTR
YRYEQTRVSFNYGQTEGKDKATDEYLSNIPAKKLAIDLSQGIMEGDMKVGTRFTYVAEQDQLPVDNVNQYDSYKLWDMYV
AWEPAMGTFEGLRVDFAVENIGDEEYRQAWQTLYEQGRNFKLSARYNF
>Mature_687_residues
TKKPVVVAMAMALSSGAFAAQTQQVSEQQITEFDEVLVTATRVSEKASETSRSVAVVTEEQLQESQPSSVAQALKNEANV
NVSNGPRASSQGVEIRGLGGQRVLQTIDGARQNTNSGHRGTYFMDPELLSSVEVVRGPASSLWGSGAIGGVVAQNTKSAA
DFLDEEDSFGGYLKQGYESNGDRIKTSGAIYGLTQTDAAGKVDWLLNGSYYDSNNIKIGNDKTLENSASQGTSGLAKFGW
EPTDEQRLQLSARFSDTDELVPSNPATNVGTSVPLVKRKTQDQNVTLDYSLNPTDNALLDLNATLYWNGTDYDEDRVTKN
QFDSTEYETLGFSLSNSSTLGNTVLTYGVDGYQDSIKTVRDDSGQFGQRPDDIDGDTTVWGAFTRADIELTETWSVDAAV
RYDAFENQSNNLNQSSDDSAFSPSVGLVWKTTDWLTLSARYDQAFRAPSMEEMYSTGTHYCIPAIPGFLPNGLCNTFEIN
PDLKAEQAENKEIKADLRFANLAGNDELAITLNVFRNDVDDFIEQSVSNPLMGIPGFEQTTSWDNVDEAKLTGFEFSTRY
RYEQTRVSFNYGQTEGKDKATDEYLSNIPAKKLAIDLSQGIMEGDMKVGTRFTYVAEQDQLPVDNVNQYDSYKLWDMYVA
WEPAMGTFEGLRVDFAVENIGDEEYRQAWQTLYEQGRNFKLSARYNF

Specific function: Required for utilization of free heme at low concentrations [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=713, Percent_Identity=22.4403927068724, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786798, Length=178, Percent_Identity=28.0898876404494, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790405, Length=156, Percent_Identity=33.974358974359, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR011276
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75968; Mature: 75836

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKPVVVAMAMALSSGAFAAQTQQVSEQQITEFDEVLVTATRVSEKASETSRSVAVVTE
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
EQLQESQPSSVAQALKNEANVNVSNGPRASSQGVEIRGLGGQRVLQTIDGARQNTNSGHR
HHHHCCCHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCC
GTYFMDPELLSSVEVVRGPASSLWGSGAIGGVVAQNTKSAADFLDEEDSFGGYLKQGYES
CEEEECHHHHHHHHHHCCCHHHHCCCCCCCCEEECCCHHHHHHCCCCCCCCHHHHHCCCC
NGDRIKTSGAIYGLTQTDAAGKVDWLLNGSYYDSNNIKIGNDKTLENSASQGTSGLAKFG
CCCEEEECCEEEEEECCCCCCCEEEEEECEEECCCCEEECCCCCCCCCCCCCCCHHHHCC
WEPTDEQRLQLSARFSDTDELVPSNPATNVGTSVPLVKRKTQDQNVTLDYSLNPTDNALL
CCCCCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCHHEECCCCCCEEEEEECCCCCCEEE
DLNATLYWNGTDYDEDRVTKNQFDSTEYETLGFSLSNSSTLGNTVLTYGVDGYQDSIKTV
EEEEEEEECCCCCCHHHCCHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHH
RDDSGQFGQRPDDIDGDTTVWGAFTRADIELTETWSVDAAVRYDAFENQSNNLNQSSDDS
HCCCCCCCCCCCCCCCCCEEEEEEEECCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
AFSPSVGLVWKTTDWLTLSARYDQAFRAPSMEEMYSTGTHYCIPAIPGFLPNGLCNTFEI
CCCCCCEEEEECCCEEEEEECHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCEEEC
NPDLKAEQAENKEIKADLRFANLAGNDELAITLNVFRNDVDDFIEQSVSNPLMGIPGFEQ
CCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEHHHHCCHHHHHHHHHCCCCCCCCCCCC
TTSWDNVDEAKLTGFEFSTRYRYEQTRVSFNYGQTEGKDKATDEYLSNIPAKKLAIDLSQ
CCCCCCCCCCEECCEEECCEEEEEEEEEEEECCCCCCCCHHHHHHHHCCCHHHEEEEHHH
GIMEGDMKVGTRFTYVAEQDQLPVDNVNQYDSYKLWDMYVAWEPAMGTFEGLRVDFAVEN
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEEECC
IGDEEYRQAWQTLYEQGRNFKLSARYNF
CCCHHHHHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure 
TKKPVVVAMAMALSSGAFAAQTQQVSEQQITEFDEVLVTATRVSEKASETSRSVAVVTE
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
EQLQESQPSSVAQALKNEANVNVSNGPRASSQGVEIRGLGGQRVLQTIDGARQNTNSGHR
HHHHCCCHHHHHHHHHHCCCEECCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCC
GTYFMDPELLSSVEVVRGPASSLWGSGAIGGVVAQNTKSAADFLDEEDSFGGYLKQGYES
CEEEECHHHHHHHHHHCCCHHHHCCCCCCCCEEECCCHHHHHHCCCCCCCCHHHHHCCCC
NGDRIKTSGAIYGLTQTDAAGKVDWLLNGSYYDSNNIKIGNDKTLENSASQGTSGLAKFG
CCCEEEECCEEEEEECCCCCCCEEEEEECEEECCCCEEECCCCCCCCCCCCCCCHHHHCC
WEPTDEQRLQLSARFSDTDELVPSNPATNVGTSVPLVKRKTQDQNVTLDYSLNPTDNALL
CCCCCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCHHEECCCCCCEEEEEECCCCCCEEE
DLNATLYWNGTDYDEDRVTKNQFDSTEYETLGFSLSNSSTLGNTVLTYGVDGYQDSIKTV
EEEEEEEECCCCCCHHHCCHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHH
RDDSGQFGQRPDDIDGDTTVWGAFTRADIELTETWSVDAAVRYDAFENQSNNLNQSSDDS
HCCCCCCCCCCCCCCCCCEEEEEEEECCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
AFSPSVGLVWKTTDWLTLSARYDQAFRAPSMEEMYSTGTHYCIPAIPGFLPNGLCNTFEI
CCCCCCEEEEECCCEEEEEECHHHHHCCCCHHHHHHCCCCEECCCCCCCCCCCCCCEEEC
NPDLKAEQAENKEIKADLRFANLAGNDELAITLNVFRNDVDDFIEQSVSNPLMGIPGFEQ
CCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEEHHHHCCHHHHHHHHHCCCCCCCCCCCC
TTSWDNVDEAKLTGFEFSTRYRYEQTRVSFNYGQTEGKDKATDEYLSNIPAKKLAIDLSQ
CCCCCCCCCCEECCEEECCEEEEEEEEEEEECCCCCCCCHHHHHHHHCCCHHHEEEEHHH
GIMEGDMKVGTRFTYVAEQDQLPVDNVNQYDSYKLWDMYVAWEPAMGTFEGLRVDFAVEN
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEEECC
IGDEEYRQAWQTLYEQGRNFKLSARYNF
CCCHHHHHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751272 [H]