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The map label for this gene is hlyB [H]

Identifier: 157963082

GI number: 157963082

Start: 4006097

End: 4007728

Strand: Reverse

Name: hlyB [H]

Synonym: Spea_3266

Alternate gene names: 157963082

Gene position: 4007728-4006097 (Counterclockwise)

Preceding gene: 157963083

Following gene: 157963081

Centisome position: 77.45

GC content: 45.22

Gene sequence:

>1632_bases
ATGTCAAATCTTTCCATCAAGCAATTATTTATTACCCTTTTTAGTAGCTTATTGATGATTTTTGCTTTGTCTCTTGGGCT
TATCAATTACCATAGCAAGCAGGTTGAAAAACAAATATACGCTCTCGAACTGGAGAACCAAACCAGTGAGCTGGTTTCGC
AGTTACTCAATAAAGTGTCTGGATTACGCCGCGAACAGTTAGGTTACAGTCTACGCCGAGTGCAGGCCTCACCAATTAGT
GAAGAGTCGAGAGAATACTTGAATCAACAGGTTGTGGATATTAACGATATTATGCTTAAGTCTGAACGGGTGGTCAGCAC
AGAGACTCAGGCGCAGCTCAGTCAGCTTAAGGATCCTATCGCCGAATTTAGTCGTCTACATCAGGACTTTCTCAATAGTG
ACACGTCTCAAGGCGCGGCGGCAGCCGGGCAGATGTTGAGCTCGATGGATGCTTGGCATATTTATAACAATGTTGAGCAG
GGTATTTTCAAGCTAATGAAGCAGCAAGCCGAAAAAGTGCTTGCTGCTAAAAATGCCGCTGCAGATGCCATGACTTCACT
AAATCGCAGCACGATTATGGTTGCAGTCGTCTTCATATTTGCCTTGTTGAGTTCAGCGATCTTCATGCTAAAGCGCATTC
TCTCGCCTCTTAACGCCACTAAGTCGGTGCTGTTAGCGATTGAGAGTGGTGATTTAACGGTTGATATCGATATGAGTCAA
TTTAATAGCCGTGAATTTAGTGATATGGCCAAGGTTTTGTTGCAAATGCGTAATCAGTTGCAGGATATCATCTCTCAGAT
CGGCGCAGGCTCTATTCAGTTGGCTGCAGCAGTAGAGGAGGTCAGTGCAATTGCTGGGGAGTCGGCTAATGGCGTGATGC
AACAGCAGCATGAAGTGGATCAAGTTGCCACCGCCATGACAGAGCTACAATCTTCAATTTCGGAAATTGCTCGTAATACT
AACCAAACAGCTGAACAAGCATTATTGGCCGTTACTGCAGCCGATAGTGGTAGCCGTGTGGTGGCTAATACCATGATAGC
GATCAATGAGTCCGAATCTGAAATCACCGCAGTGAGTGAAGTGATCAGCCAACTTCAGCAAGACACAGATGCGATTTCTG
TCATTGCCGAGGTGATTACCAATATTACCGATCAGACTAACTTACTGGCTTTGAATGCCGCAATTGAAGCCGCTCGAGCT
GGTGAGCAAGGGCGTGGTTTTGCGGTCGTTGCAGATGAAGTGAGAACATTGGCTAGCCGTACTCAAGATTCAGCCCATGA
AATAAAATCGACGATTGAACTGCTGCAAAATCGTTCAAAAACAGCTGTTAAAGTCATGAGCTCAAGCCGGGATAAGATGA
AGCATAGCGTCGAGCAGGCAAGTTGCGCTAGCGCGGCGATTGAGGATATTAATGCTGCGATCACGCAAATTAATGATATG
GCAATTCAAGTTGCTAGCGCGACAGAGCAACAAACAGCAGTAACTGAAGAGCTGAGTCAAAACATTATTAATATTAGCGA
TGCAGCTTGTCGAGTGAGTGAAGGTACGGTCCAAGTGTCTCAATCAAGCAATGAATTAAGTCAGTTAGCGGTAAACCTAG
ACGAAATTATCCGTCGATTCCGCACGGTATAG

Upstream 100 bases:

>100_bases
TACGAGTCAATATTTGTCAGTCGGTCACAGTTTCGACCAAGTAAACTGATAGTATTCCGATCCTTTTTAATATGCCTGCA
TAGGTTTAAACGGTTTTAGT

Downstream 100 bases:

>100_bases
CTAATCAGTATCTTTTGTTGAATTCGGTAGTGCAGGCTATCGAATTCAACAGCCTCTTTTGTATTACCATCTCAGTGTTT
ACTCTTTTTATTTATTATTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSNLSIKQLFITLFSSLLMIFALSLGLINYHSKQVEKQIYALELENQTSELVSQLLNKVSGLRREQLGYSLRRVQASPIS
EESREYLNQQVVDINDIMLKSERVVSTETQAQLSQLKDPIAEFSRLHQDFLNSDTSQGAAAAGQMLSSMDAWHIYNNVEQ
GIFKLMKQQAEKVLAAKNAAADAMTSLNRSTIMVAVVFIFALLSSAIFMLKRILSPLNATKSVLLAIESGDLTVDIDMSQ
FNSREFSDMAKVLLQMRNQLQDIISQIGAGSIQLAAAVEEVSAIAGESANGVMQQQHEVDQVATAMTELQSSISEIARNT
NQTAEQALLAVTAADSGSRVVANTMIAINESESEITAVSEVISQLQQDTDAISVIAEVITNITDQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTQDSAHEIKSTIELLQNRSKTAVKVMSSSRDKMKHSVEQASCASAAIEDINAAITQINDM
AIQVASATEQQTAVTEELSQNIINISDAACRVSEGTVQVSQSSNELSQLAVNLDEIIRRFRTV

Sequences:

>Translated_543_residues
MSNLSIKQLFITLFSSLLMIFALSLGLINYHSKQVEKQIYALELENQTSELVSQLLNKVSGLRREQLGYSLRRVQASPIS
EESREYLNQQVVDINDIMLKSERVVSTETQAQLSQLKDPIAEFSRLHQDFLNSDTSQGAAAAGQMLSSMDAWHIYNNVEQ
GIFKLMKQQAEKVLAAKNAAADAMTSLNRSTIMVAVVFIFALLSSAIFMLKRILSPLNATKSVLLAIESGDLTVDIDMSQ
FNSREFSDMAKVLLQMRNQLQDIISQIGAGSIQLAAAVEEVSAIAGESANGVMQQQHEVDQVATAMTELQSSISEIARNT
NQTAEQALLAVTAADSGSRVVANTMIAINESESEITAVSEVISQLQQDTDAISVIAEVITNITDQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTQDSAHEIKSTIELLQNRSKTAVKVMSSSRDKMKHSVEQASCASAAIEDINAAITQINDM
AIQVASATEQQTAVTEELSQNIINISDAACRVSEGTVQVSQSSNELSQLAVNLDEIIRRFRTV
>Mature_542_residues
SNLSIKQLFITLFSSLLMIFALSLGLINYHSKQVEKQIYALELENQTSELVSQLLNKVSGLRREQLGYSLRRVQASPISE
ESREYLNQQVVDINDIMLKSERVVSTETQAQLSQLKDPIAEFSRLHQDFLNSDTSQGAAAAGQMLSSMDAWHIYNNVEQG
IFKLMKQQAEKVLAAKNAAADAMTSLNRSTIMVAVVFIFALLSSAIFMLKRILSPLNATKSVLLAIESGDLTVDIDMSQF
NSREFSDMAKVLLQMRNQLQDIISQIGAGSIQLAAAVEEVSAIAGESANGVMQQQHEVDQVATAMTELQSSISEIARNTN
QTAEQALLAVTAADSGSRVVANTMIAINESESEITAVSEVISQLQQDTDAISVIAEVITNITDQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLASRTQDSAHEIKSTIELLQNRSKTAVKVMSSSRDKMKHSVEQASCASAAIEDINAAITQINDMA
IQVASATEQQTAVTEELSQNIINISDAACRVSEGTVQVSQSSNELSQLAVNLDEIIRRFRTV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=346, Percent_Identity=30.9248554913295, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=33.033033033033, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367378, Length=303, Percent_Identity=29.7029702970297, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=288, Percent_Identity=31.5972222222222, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789453, Length=305, Percent_Identity=28.1967213114754, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59009; Mature: 58877

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLSIKQLFITLFSSLLMIFALSLGLINYHSKQVEKQIYALELENQTSELVSQLLNKVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
GLRREQLGYSLRRVQASPISEESREYLNQQVVDINDIMLKSERVVSTETQAQLSQLKDPI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
AEFSRLHQDFLNSDTSQGAAAAGQMLSSMDAWHIYNNVEQGIFKLMKQQAEKVLAAKNAA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAMTSLNRSTIMVAVVFIFALLSSAIFMLKRILSPLNATKSVLLAIESGDLTVDIDMSQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCEEEEEEHHH
FNSREFSDMAKVLLQMRNQLQDIISQIGAGSIQLAAAVEEVSAIAGESANGVMQQQHEVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QVATAMTELQSSISEIARNTNQTAEQALLAVTAADSGSRVVANTMIAINESESEITAVSE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCEEHHHHEEEEECCHHHHHHHHH
VISQLQQDTDAISVIAEVITNITDQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TQDSAHEIKSTIELLQNRSKTAVKVMSSSRDKMKHSVEQASCASAAIEDINAAITQINDM
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIQVASATEQQTAVTEELSQNIINISDAACRVSEGTVQVSQSSNELSQLAVNLDEIIRRF
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCEEECCCHHHHHHHHHHHHHHHHHH
RTV
CCC
>Mature Secondary Structure 
SNLSIKQLFITLFSSLLMIFALSLGLINYHSKQVEKQIYALELENQTSELVSQLLNKVS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHH
GLRREQLGYSLRRVQASPISEESREYLNQQVVDINDIMLKSERVVSTETQAQLSQLKDPI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
AEFSRLHQDFLNSDTSQGAAAAGQMLSSMDAWHIYNNVEQGIFKLMKQQAEKVLAAKNAA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAMTSLNRSTIMVAVVFIFALLSSAIFMLKRILSPLNATKSVLLAIESGDLTVDIDMSQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCEEEEEEHHH
FNSREFSDMAKVLLQMRNQLQDIISQIGAGSIQLAAAVEEVSAIAGESANGVMQQQHEVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QVATAMTELQSSISEIARNTNQTAEQALLAVTAADSGSRVVANTMIAINESESEITAVSE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCEEHHHHEEEEECCHHHHHHHHH
VISQLQQDTDAISVIAEVITNITDQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TQDSAHEIKSTIELLQNRSKTAVKVMSSSRDKMKHSVEQASCASAAIEDINAAITQINDM
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIQVASATEQQTAVTEELSQNIINISDAACRVSEGTVQVSQSSNELSQLAVNLDEIIRRF
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCEEECCCHHHHHHHHHHHHHHHHHH
RTV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]