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The map label for this gene is kdsA [H]

Identifier: 157962938

GI number: 157962938

Start: 3824190

End: 3825038

Strand: Reverse

Name: kdsA [H]

Synonym: Spea_3121

Alternate gene names: 157962938

Gene position: 3825038-3824190 (Counterclockwise)

Preceding gene: 157962939

Following gene: 157962937

Centisome position: 73.92

GC content: 46.29

Gene sequence:

>849_bases
ATGAGCAATAAAATCATTAGTTTAGGTTCGATTGAGATCGCAAATGATAAGCCTTTTGTATTATTTGGCGGTATGAACGT
ACTTGAGTCACGTGACTTGGCAATGCAAATTGCAGAAACCTATGCTGAAGTTACCCAAAAGTTAGGGATCCCTTACGTGT
TTAAGGCCTCTTTCGATAAGGCTAACCGCTCATCAGTTAACTCTTACCGTGGCCCAGGCATGGAAGAAGGCTTGAAGATC
TTTGAAGAGATTAAATCGACTTTTAACTTGCCTTTGATCACTGACGTACACGAAGTGCACCAGTGTGCGCCAGTTGCAGA
AGTCGTTGATGTGATTCAGTTGCCTGCATTCCTTGCTCGTCAAACAGATCTTGTTGTGGCGATGGCAAAGACAGGCGCCA
TTATTAACGTGAAAAAGCCGCAGTTCTTAGCTCCACATGAGATGCGTCATATCATTACTAAGTTTAATGAAGCGGGTAAC
GATGAGATCATGCTGTGTGAACGTGGTTCGAGCTTTGGTTACAACAACCTCGTTGTCGATATGCTAGGTATGGATGAGAT
GAAGCAAACGGGTTACCCGGTGATCTTCGATGCGACTCATGCTCTGCAACGTCCTGGTGGACGTAGCGACAGCGCTGGTG
GACGCCGCGCTCAAGCGACAGAGCTTGCCCGTAGTGGTATGGCACTTGGCTTAGCGGGCTTGTTTATTGAGGCTCACCCA
GATCCTGATAACGCTAAGTGTGACGGCCCGTGTGCATTGCCACTACACCAGTTAGAGAACTACTTAACCCAGATGAAGGC
GATTGACGATTTAGTTAAGTCGTTTGAGCCTATTGATACTAGTAAGTAA

Upstream 100 bases:

>100_bases
TGGCCAAATTTTACAAGCTGTCGCCAGTTAAGGCCGCAGCAAAAACTTAGTTGATTAATGCCAAGGCAACGGCCTTGGCT
CACGAAGAGAGAAGAGATTG

Downstream 100 bases:

>100_bases
GTTCGAAGTATTTTATTCTTCTAGCTAGTTGTAATAAAAGATAAAACCCTGTCTTAGCGCAGGGTTTTATTTTTTTCATC
GATATAATTTAAGTTTAAAT

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSNKIISLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKI
FEEIKSTFNLPLITDVHEVHQCAPVAEVVDVIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGN
DEIMLCERGSSFGYNNLVVDMLGMDEMKQTGYPVIFDATHALQRPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHP
DPDNAKCDGPCALPLHQLENYLTQMKAIDDLVKSFEPIDTSK

Sequences:

>Translated_282_residues
MSNKIISLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKI
FEEIKSTFNLPLITDVHEVHQCAPVAEVVDVIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGN
DEIMLCERGSSFGYNNLVVDMLGMDEMKQTGYPVIFDATHALQRPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHP
DPDNAKCDGPCALPLHQLENYLTQMKAIDDLVKSFEPIDTSK
>Mature_281_residues
SNKIISLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKIF
EEIKSTFNLPLITDVHEVHQCAPVAEVVDVIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGND
EIMLCERGSSFGYNNLVVDMLGMDEMKQTGYPVIFDATHALQRPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHPD
PDNAKCDGPCALPLHQLENYLTQMKAIDDLVKSFEPIDTSK

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=284, Percent_Identity=70.4225352112676, Blast_Score=416, Evalue=1e-118,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 30873; Mature: 30742

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKIISLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDK
CCCCEEEECCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ANRSSVNSYRGPGMEEGLKIFEEIKSTFNLPLITDVHEVHQCAPVAEVVDVIQLPAFLAR
CCHHHCHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHC
QTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGNDEIMLCERGSSFGYNNLVVD
CCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEE
MLGMDEMKQTGYPVIFDATHALQRPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHP
HHCCHHHHHCCCCEEEECHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHEEEEEEEEECC
DPDNAKCDGPCALPLHQLENYLTQMKAIDDLVKSFEPIDTSK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNKIISLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDK
CCCEEEECCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ANRSSVNSYRGPGMEEGLKIFEEIKSTFNLPLITDVHEVHQCAPVAEVVDVIQLPAFLAR
CCHHHCHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHC
QTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGNDEIMLCERGSSFGYNNLVVD
CCCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEE
MLGMDEMKQTGYPVIFDATHALQRPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHP
HHCCHHHHHCCCCEEEECHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHEEEEEEEEECC
DPDNAKCDGPCALPLHQLENYLTQMKAIDDLVKSFEPIDTSK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA