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The map label for this gene is erg3 [H]

Identifier: 157962925

GI number: 157962925

Start: 3810468

End: 3811415

Strand: Reverse

Name: erg3 [H]

Synonym: Spea_3108

Alternate gene names: 157962925

Gene position: 3811415-3810468 (Counterclockwise)

Preceding gene: 157962926

Following gene: 157962923

Centisome position: 73.66

GC content: 43.78

Gene sequence:

>948_bases
ATGGATTTTAATTCACTGATAGCACACCCCGAAGTGCTACTACTGGTACTCGCGCCGATTTTTTTCGTCTGCATCTTACT
CGAGTGGTATATGGGCGATAGGCAAAACCGTTTACCCCTCAATGCTCGTTATCGCTTGCCTGAGGTGTTGTGTAACTTCG
GTTTAGCGGCAATGCATCAATTGACCGATATTGTTACTGGACTGCTTATTGCTAAGTTATACCTGATGTTCTTCGGTTGG
CGTCTTTTCGATATAGAGATGAATGCTGCGACATTTATTGTGCTAATGGTTGCGCAAGATTTCTGTTACTACTGGTTCCA
CCGAGCGAGTCACCGTATTCGCTGGATGTGGGCTGCTCATGTGGCTCATCATAGTTCTGAGAATATGAACTTTAGTACTG
CTTTTAGGCAAAGCTTAATGTACCCAATGGCTGGGATGTGGATATTCTGGTTGCCGTTAGTCATAGTCGGTTTTGACCCT
AATTGGGTGGTGTTTGTGGTACTGCTGAACTTAGGGCTACAGTTTTTTGTCCATACACAGGCGGTTAAATCTTTAGGTAT
ATTGGAGTGGGTTATTAATACCCCGTCTCATCATCGAGTTCATCATGGCCGCAATCCACAATATATCGATAAGAATTATG
CTGGTATTTTGATTATTTGGGATCGAATGTTCGGCACGTACGAGAAAGAAGTTGAGACCGTAGAGTATGGGATCACTAAA
CCAATCAATAGCTTTAACCCGCTGGTGGTAACCTTTTCCGAGTGGCGAGATATGTTTAAAGAAGCGATTTCTGCCAACTT
AAGCCCTAAGCAAAGGTTTCGAGTGTTATTTGATCCACCGGCAAGCGCGACAGCGCAGGTGGGAGAGCAAAACTCTACTG
TGCAAGATGTTGAAGAAAAGCATGAAAAGCATGAAAAGCATGAAAAGCAGGTAGCTGAGATTAAGTAG

Upstream 100 bases:

>100_bases
TGATGGCTAGAGTCATAAACCAAAATAAAAAACGATTAAAGCGGTGAAAAGTGGCGAGACATATAAGTCGAGGCCCCCAA
GGATAAAAAGGATATATAAG

Downstream 100 bases:

>100_bases
CGACTATTTAATGAATCAAAAACAAAACGGTGAGCCTAGGCTCACCGTTTTTGCTTAACCGCTTATATTTAACCGCTTAT
GTCTATTTAGCGAGCGGTTA

Product: fatty acid hydroxylase

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MDFNSLIAHPEVLLLVLAPIFFVCILLEWYMGDRQNRLPLNARYRLPEVLCNFGLAAMHQLTDIVTGLLIAKLYLMFFGW
RLFDIEMNAATFIVLMVAQDFCYYWFHRASHRIRWMWAAHVAHHSSENMNFSTAFRQSLMYPMAGMWIFWLPLVIVGFDP
NWVVFVVLLNLGLQFFVHTQAVKSLGILEWVINTPSHHRVHHGRNPQYIDKNYAGILIIWDRMFGTYEKEVETVEYGITK
PINSFNPLVVTFSEWRDMFKEAISANLSPKQRFRVLFDPPASATAQVGEQNSTVQDVEEKHEKHEKHEKQVAEIK

Sequences:

>Translated_315_residues
MDFNSLIAHPEVLLLVLAPIFFVCILLEWYMGDRQNRLPLNARYRLPEVLCNFGLAAMHQLTDIVTGLLIAKLYLMFFGW
RLFDIEMNAATFIVLMVAQDFCYYWFHRASHRIRWMWAAHVAHHSSENMNFSTAFRQSLMYPMAGMWIFWLPLVIVGFDP
NWVVFVVLLNLGLQFFVHTQAVKSLGILEWVINTPSHHRVHHGRNPQYIDKNYAGILIIWDRMFGTYEKEVETVEYGITK
PINSFNPLVVTFSEWRDMFKEAISANLSPKQRFRVLFDPPASATAQVGEQNSTVQDVEEKHEKHEKHEKQVAEIK
>Mature_315_residues
MDFNSLIAHPEVLLLVLAPIFFVCILLEWYMGDRQNRLPLNARYRLPEVLCNFGLAAMHQLTDIVTGLLIAKLYLMFFGW
RLFDIEMNAATFIVLMVAQDFCYYWFHRASHRIRWMWAAHVAHHSSENMNFSTAFRQSLMYPMAGMWIFWLPLVIVGFDP
NWVVFVVLLNLGLQFFVHTQAVKSLGILEWVINTPSHHRVHHGRNPQYIDKNYAGILIIWDRMFGTYEKEVETVEYGITK
PINSFNPLVVTFSEWRDMFKEAISANLSPKQRFRVLFDPPASATAQVGEQNSTVQDVEEKHEKHEKHEKQVAEIK

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=207, Percent_Identity=47.8260869565217, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144659, Length=183, Percent_Identity=42.0765027322404, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 36848; Mature: 36848

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNSLIAHPEVLLLVLAPIFFVCILLEWYMGDRQNRLPLNARYRLPEVLCNFGLAAMHQ
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHHH
LTDIVTGLLIAKLYLMFFGWRLFDIEMNAATFIVLMVAQDFCYYWFHRASHRIRWMWAAH
HHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VAHHSSENMNFSTAFRQSLMYPMAGMWIFWLPLVIVGFDPNWVVFVVLLNLGLQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVKSLGILEWVINTPSHHRVHHGRNPQYIDKNYAGILIIWDRMFGTYEKEVETVEYGITK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHCCCC
PINSFNPLVVTFSEWRDMFKEAISANLSPKQRFRVLFDPPASATAQVGEQNSTVQDVEEK
CCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHEEEEECCCCCHHHHCCCCCCHHHHHHHH
HEKHEKHEKQVAEIK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFNSLIAHPEVLLLVLAPIFFVCILLEWYMGDRQNRLPLNARYRLPEVLCNFGLAAMHQ
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHHH
LTDIVTGLLIAKLYLMFFGWRLFDIEMNAATFIVLMVAQDFCYYWFHRASHRIRWMWAAH
HHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VAHHSSENMNFSTAFRQSLMYPMAGMWIFWLPLVIVGFDPNWVVFVVLLNLGLQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AVKSLGILEWVINTPSHHRVHHGRNPQYIDKNYAGILIIWDRMFGTYEKEVETVEYGITK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCHHHHHHHHHHHCCCC
PINSFNPLVVTFSEWRDMFKEAISANLSPKQRFRVLFDPPASATAQVGEQNSTVQDVEEK
CCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHEEEEECCCCCHHHHCCCCCCHHHHHHHH
HEKHEKHEKQVAEIK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]