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The map label for this gene is dinB [H]

Identifier: 157962909

GI number: 157962909

Start: 3796092

End: 3797168

Strand: Reverse

Name: dinB [H]

Synonym: Spea_3092

Alternate gene names: 157962909

Gene position: 3797168-3796092 (Counterclockwise)

Preceding gene: 157962910

Following gene: 157962907

Centisome position: 73.38

GC content: 46.61

Gene sequence:

>1077_bases
TTGCAAAAAATTATTCATGTCGACATGGATTGCTTCTACGCCGCAGTAGAAATGCGTGACTTTCCCGAATTAAGAGGAAA
ACCTATAGCTGTGGGTGGGCGCAGCGATCGCCGTGGAGTGATAAGCACCTGTAACTACGAGGCGCGTCAGTTTGGCGTAC
GCTCAGCCATGGCATCAGGATACGCTCTTAAGTTATGTCCCGATTTGATTCTGGTTCCAGGGAGGATGCAGGTCTATAAA
GAGGTGTCGAGCCAGATCCGAGCTGTATTTGAGCGCTATACCTACTTAATAGAGCCGTTATCGCTAGATGAGGCGTACCT
CGATGTAACAGATAGTCCCCATTGTAAGGGCTCAGCAACCTTAATTGCCGAGGCTATTCGCGCCGACATCTTGGCCGAAA
CGGGTCTAACCGCATCTGCAGGAATCGCACCGGTTAAATTTCTAGCCAAGATAGCCTCAGATTTAAATAAACCCAATGGA
CAATATGTGATCCGCCCAGACATGATTAATGAGTTTGTTAAAACACTACCGCTGATAAAAATTCCAGGTGTTGGTAAGGT
TACCGCTAAAAAATTAGCCGATTTAGGCTTGCATACTTGCAGTGATGTACAGGCGTACCCCCCTGCGCAGTTGATTGAAC
GTTTTGGCAAATTTGGAACTGTGCTGATAGAGCGTTCCAAAGGAGTCGATAAGCGGGGTATTTCCCCTAATAGAGAGAGA
AAGTCAGTTGGGGTTGAAACCACCTTAGCCAAAGATATTCACACGCTGGAACAATGCCGAGCGGTAATGCCCCAGCTTAT
TCAAGAGCTAGGTGCACGAGTGAGTCGCAGTGCCAAGGACAGGACTATCCACAAGCAGGTGGTTAAAATTAAGTTTGAGG
ATTTTAAACAGACAACGATTGAACATCGCAGTGATGATATCTCGGTAAACTTGTTTTATCAGTTACTCGAACAAGCGATG
GAGAGACAGCATGAGCGCGGCATTCGTCTCTTGGGGGTATCTGTTGGCCTTGCTTCTAATAGTTCGACAACAGATGATAG
CGATGTGGATAGTTCGCAGTTGGATTTAGGCTTTTAG

Upstream 100 bases:

>100_bases
TATTTTTTACTCTCGGTTTTCTGGTATGGCATTGAGTAAGTATGGTTTATATTGAATACTGTTTTTATATACAGTAATAT
TCTTTTCGGAGGATATTGGC

Downstream 100 bases:

>100_bases
GTGTATAGCCAGAAATGGCTCGTTAGAAAAAACAAAGGCCACTTACTGCTAATTAATAGCTAAGTGGCCTTTTAGGTTTT
ACTTTGAAGTTAAGAGAGTA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MQKIIHVDMDCFYAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARQFGVRSAMASGYALKLCPDLILVPGRMQVYK
EVSSQIRAVFERYTYLIEPLSLDEAYLDVTDSPHCKGSATLIAEAIRADILAETGLTASAGIAPVKFLAKIASDLNKPNG
QYVIRPDMINEFVKTLPLIKIPGVGKVTAKKLADLGLHTCSDVQAYPPAQLIERFGKFGTVLIERSKGVDKRGISPNRER
KSVGVETTLAKDIHTLEQCRAVMPQLIQELGARVSRSAKDRTIHKQVVKIKFEDFKQTTIEHRSDDISVNLFYQLLEQAM
ERQHERGIRLLGVSVGLASNSSTTDDSDVDSSQLDLGF

Sequences:

>Translated_358_residues
MQKIIHVDMDCFYAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARQFGVRSAMASGYALKLCPDLILVPGRMQVYK
EVSSQIRAVFERYTYLIEPLSLDEAYLDVTDSPHCKGSATLIAEAIRADILAETGLTASAGIAPVKFLAKIASDLNKPNG
QYVIRPDMINEFVKTLPLIKIPGVGKVTAKKLADLGLHTCSDVQAYPPAQLIERFGKFGTVLIERSKGVDKRGISPNRER
KSVGVETTLAKDIHTLEQCRAVMPQLIQELGARVSRSAKDRTIHKQVVKIKFEDFKQTTIEHRSDDISVNLFYQLLEQAM
ERQHERGIRLLGVSVGLASNSSTTDDSDVDSSQLDLGF
>Mature_358_residues
MQKIIHVDMDCFYAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARQFGVRSAMASGYALKLCPDLILVPGRMQVYK
EVSSQIRAVFERYTYLIEPLSLDEAYLDVTDSPHCKGSATLIAEAIRADILAETGLTASAGIAPVKFLAKIASDLNKPNG
QYVIRPDMINEFVKTLPLIKIPGVGKVTAKKLADLGLHTCSDVQAYPPAQLIERFGKFGTVLIERSKGVDKRGISPNRER
KSVGVETTLAKDIHTLEQCRAVMPQLIQELGARVSRSAKDRTIHKQVVKIKFEDFKQTTIEHRSDDISVNLFYQLLEQAM
ERQHERGIRLLGVSVGLASNSSTTDDSDVDSSQLDLGF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=32.0987654320988, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=31.6923076923077, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI154350220, Length=249, Percent_Identity=34.136546184739, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI5729982, Length=362, Percent_Identity=30.1104972375691, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=52.3364485981308, Blast_Score=118, Evalue=9e-27,
Organism=Escherichia coli, GI1786425, Length=338, Percent_Identity=59.7633136094675, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1787432, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=399, Percent_Identity=31.077694235589, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17537959, Length=302, Percent_Identity=27.4834437086093, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193205702, Length=337, Percent_Identity=28.486646884273, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=375, Percent_Identity=24.8, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324921, Length=205, Percent_Identity=30.2439024390244, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19923006, Length=336, Percent_Identity=30.6547619047619, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI21355641, Length=363, Percent_Identity=29.2011019283747, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644984, Length=363, Percent_Identity=29.2011019283747, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668444, Length=117, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- InterPro:   IPR003583 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39643; Mature: 39643

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIIHVDMDCFYAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARQFGVRSAMASG
CCCEEEECHHHHHHHHHHHCCHHHCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHCC
YALKLCPDLILVPGRMQVYKEVSSQIRAVFERYTYLIEPLSLDEAYLDVTDSPHCKGSAT
CEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCHHH
LIAEAIRADILAETGLTASAGIAPVKFLAKIASDLNKPNGQYVIRPDMINEFVKTLPLIK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCCEE
IPGVGKVTAKKLADLGLHTCSDVQAYPPAQLIERFGKFGTVLIERSKGVDKRGISPNRER
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHH
KSVGVETTLAKDIHTLEQCRAVMPQLIQELGARVSRSAKDRTIHKQVVKIKFEDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EHRSDDISVNLFYQLLEQAMERQHERGIRLLGVSVGLASNSSTTDDSDVDSSQLDLGF
HHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQKIIHVDMDCFYAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARQFGVRSAMASG
CCCEEEECHHHHHHHHHHHCCHHHCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHHHHCC
YALKLCPDLILVPGRMQVYKEVSSQIRAVFERYTYLIEPLSLDEAYLDVTDSPHCKGSAT
CEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCHHH
LIAEAIRADILAETGLTASAGIAPVKFLAKIASDLNKPNGQYVIRPDMINEFVKTLPLIK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCCEE
IPGVGKVTAKKLADLGLHTCSDVQAYPPAQLIERFGKFGTVLIERSKGVDKRGISPNRER
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHH
KSVGVETTLAKDIHTLEQCRAVMPQLIQELGARVSRSAKDRTIHKQVVKIKFEDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EHRSDDISVNLFYQLLEQAMERQHERGIRLLGVSVGLASNSSTTDDSDVDSSQLDLGF
HHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA