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The map label for this gene is betT [H]

Identifier: 157962562

GI number: 157962562

Start: 3348453

End: 3350438

Strand: Reverse

Name: betT [H]

Synonym: Spea_2741

Alternate gene names: 157962562

Gene position: 3350438-3348453 (Counterclockwise)

Preceding gene: 157962563

Following gene: 157962561

Centisome position: 64.75

GC content: 45.17

Gene sequence:

>1986_bases
ATGTCGATAAAATCGAGTATTAATCCACCTGTTTTTTTCTCCTCAGTCATTTTAATCACCTTAATGGTTGCAGTTTGCGC
CATTTGGCCCACTCAGTCACAAGATGTATTCAAAACAGCTCAATCATGGTTCGAGCTTAAAGCTGGCTGGCTCTACATCT
TGGGCGTAGCGGTATTTCTTATCTTTATCATCTTCGTGATGGTGAGCCGCTTTGGCGATATCAAGTTAGGCCCTGATCAT
GCTGAGCCTGATTACACCTATAAAAGCTGGATCGCAATGCTGTTTTCAGCCGGTATGGGTATCGGCTTGATGTTCTTCGG
TGTGGCAGAGCCTGTGATGCACTACATGTCTCCGCCAGATGCGGATCCATTGACCATTCAAGCGGCAAAAGATGCCATGA
AGATCACCTTTTTCCATTGGGGTGTTCATGCTTGGGCTATCTATGCTGTTGTGGCATTAAGTTTGGCGTACTTCTCCTAC
CGTCATAAACTGCCTTTACTGCCTAGAAGTGCCTTATACCCGTTAATTGGCGATAAGATCTACGGCCCAATTGGTCATGC
CGTCGATACTTTTGCGGTACTCGGTACCATGTTCGGTGTAGCGACTTCACTCGGCTTTGGTGTACTACAGCTTAACTCTG
GCCTTAACTACCTGTTAGGTGTGCCAGTTAGCACTACGGTACAAGTTTGCTTAATTATCGGTGTCTGTCTAATTGCGACT
GTGTCAGTGTTCTCAGGCTTAGACAAGGGTGTTAAGCGCTTAAGTGAATTAAACCTTCTGCTAGCGGTATTATTGCTATT
GTTTGTGCTTGTATTTGGTCCAACGGTTGAACTACTGCAAGCATTTGTACAAAACACCGGTGCGTATTTAAGTGATATCG
TCGGTAAGACGTTTAACTTATATGCCTATGAGCAGAAGAATGACTGGATTGGTGGTTGGACGCTACTTTACTGGGGCTGG
TGGATCTCATGGTCTCCATTTGTCGGTACTTTTATTGCTCGTGTTTCTCGTGGTCGTACCATTCGTGAATTCTTAGTGGG
TGTCTTGTTTGTACCGTCTGCGCTGACCTTCCTGTGGATGACAGGCTTTGGTAATAGCGCTATTGATGTGATTTCAAATG
GCGGAACCTATCTGTCTGACGCTGTAGCATCTGATGTCTCGGTTGCTCTGTTCGTGTTTTTTGAGCATTTACCGTTCTCA
ACCTTGCTGTCGACGATTGCACTTTGTTTAGTTGTTACTTTCTTCGTGACATCATCCGACTCAGGCTCTTTGGTTATTGA
TAACCTGACATCGGGCGGCGATCATAACGCACCAGTATGGCAGCGTATTTTCTGGGCCTTAATGCAAGGTGTTGTGGCAT
CGGTTCTATTGCTAGCCGGTGGTTTACAAGCCCTGCAAACCGCGGCGATTGCCAGTGCGCTACCTTTCTTAATCGTTATG
CTATTGATGTGTTTTGGCCTATACAAAGCGCTTAAAGACGATTGGTTGAAGATCAACAGTGTTCAGTCTCACAATACTAG
CGTGCAGTTCACTAAGACCAACGTAAGTTGGGAATCGCATATTGACGTATTGCTGTCTCACCCAAGCCAGCAAGAAGCCC
AAGATTTCTTAGATAAGGTGGCGCAGCCAGCATTATCAAAAGTATGTGAAAGCTTCCTAAGTCGCTCGATTTCGGCGGAG
ATCTTAAACTTCGACAATCGTGTGCGTTTTGTGGTCCATAGTGAAGAGCATAATGACTTCGTGTATGGCCTACGTATTCG
TGCCTATACCATCTCTAATCCGTTAGACAGTGACGTTAGCAATGATGATGGTGATAACTTCTACTACCGCGTAGAAGTCT
TCCTTGAGCACGGCGGTCAACACTATGACGTGATGGGCTTTACTCAAGAACAGATCCTGGCAGATGTAGTGACTCAGTAT
GAGAAATACTTACATTACCTGCATTTATCAAGTTCAGAGTATTTAAGCAGTGAAACTAACGCTTAG

Upstream 100 bases:

>100_bases
ACCAGTGTATTCTGATATTAGCTAATACGCTTTTATCTCTGGCGGCCTTGTCACGTAAAGCTAGAATTAGTGCGTGTACT
TCATTAATCGCGGTAACTAT

Downstream 100 bases:

>100_bases
TCTGACATGACTGGCAAAAACGTTAGTCAGTAAGTATTGGTAAAACGTTAATTTGTCATTATTGGCGAAATGTTAGTCAG
TAAGTTATGGGTAAAACGTT

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSIKSSINPPVFFSSVILITLMVAVCAIWPTQSQDVFKTAQSWFELKAGWLYILGVAVFLIFIIFVMVSRFGDIKLGPDH
AEPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMSPPDADPLTIQAAKDAMKITFFHWGVHAWAIYAVVALSLAYFSY
RHKLPLLPRSALYPLIGDKIYGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLGVPVSTTVQVCLIIGVCLIAT
VSVFSGLDKGVKRLSELNLLLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNLYAYEQKNDWIGGWTLLYWGW
WISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWMTGFGNSAIDVISNGGTYLSDAVASDVSVALFVFFEHLPFS
TLLSTIALCLVVTFFVTSSDSGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVM
LLMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKVAQPALSKVCESFLSRSISAE
ILNFDNRVRFVVHSEEHNDFVYGLRIRAYTISNPLDSDVSNDDGDNFYYRVEVFLEHGGQHYDVMGFTQEQILADVVTQY
EKYLHYLHLSSSEYLSSETNA

Sequences:

>Translated_661_residues
MSIKSSINPPVFFSSVILITLMVAVCAIWPTQSQDVFKTAQSWFELKAGWLYILGVAVFLIFIIFVMVSRFGDIKLGPDH
AEPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMSPPDADPLTIQAAKDAMKITFFHWGVHAWAIYAVVALSLAYFSY
RHKLPLLPRSALYPLIGDKIYGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLGVPVSTTVQVCLIIGVCLIAT
VSVFSGLDKGVKRLSELNLLLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNLYAYEQKNDWIGGWTLLYWGW
WISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWMTGFGNSAIDVISNGGTYLSDAVASDVSVALFVFFEHLPFS
TLLSTIALCLVVTFFVTSSDSGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVM
LLMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKVAQPALSKVCESFLSRSISAE
ILNFDNRVRFVVHSEEHNDFVYGLRIRAYTISNPLDSDVSNDDGDNFYYRVEVFLEHGGQHYDVMGFTQEQILADVVTQY
EKYLHYLHLSSSEYLSSETNA
>Mature_660_residues
SIKSSINPPVFFSSVILITLMVAVCAIWPTQSQDVFKTAQSWFELKAGWLYILGVAVFLIFIIFVMVSRFGDIKLGPDHA
EPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMSPPDADPLTIQAAKDAMKITFFHWGVHAWAIYAVVALSLAYFSYR
HKLPLLPRSALYPLIGDKIYGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLGVPVSTTVQVCLIIGVCLIATV
SVFSGLDKGVKRLSELNLLLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNLYAYEQKNDWIGGWTLLYWGWW
ISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWMTGFGNSAIDVISNGGTYLSDAVASDVSVALFVFFEHLPFST
LLSTIALCLVVTFFVTSSDSGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVML
LMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKVAQPALSKVCESFLSRSISAEI
LNFDNRVRFVVHSEEHNDFVYGLRIRAYTISNPLDSDVSNDDGDNFYYRVEVFLEHGGQHYDVMGFTQEQILADVVTQYE
KYLHYLHLSSSEYLSSETNA

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=657, Percent_Identity=38.9649923896499, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1786224, Length=502, Percent_Identity=26.4940239043825, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1788102, Length=456, Percent_Identity=29.1666666666667, Blast_Score=175, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 73172; Mature: 73041

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKSSINPPVFFSSVILITLMVAVCAIWPTQSQDVFKTAQSWFELKAGWLYILGVAVFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFIIFVMVSRFGDIKLGPDHAEPDYTYKSWIAMLFSAGMGIGLMFFGVAEPVMHYMSPPD
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
ADPLTIQAAKDAMKITFFHWGVHAWAIYAVVALSLAYFSYRHKLPLLPRSALYPLIGDKI
CCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHH
YGPIGHAVDTFAVLGTMFGVATSLGFGVLQLNSGLNYLLGVPVSTTVQVCLIIGVCLIAT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHH
VSVFSGLDKGVKRLSELNLLLAVLLLLFVLVFGPTVELLQAFVQNTGAYLSDIVGKTFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCEEE
YAYEQKNDWIGGWTLLYWGWWISWSPFVGTFIARVSRGRTIREFLVGVLFVPSALTFLWM
EEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TGFGNSAIDVISNGGTYLSDAVASDVSVALFVFFEHLPFSTLLSTIALCLVVTFFVTSSD
HCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
SGSLVIDNLTSGGDHNAPVWQRIFWALMQGVVASVLLLAGGLQALQTAAIASALPFLIVM
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LLMCFGLYKALKDDWLKINSVQSHNTSVQFTKTNVSWESHIDVLLSHPSQQEAQDFLDKV
HHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHH
AQPALSKVCESFLSRSISAEILNFDNRVRFVVHSEEHNDFVYGLRIRAYTISNPLDSDVS
HHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCC
NDDGDNFYYRVEVFLEHGGQHYDVMGFTQEQILADVVTQYEKYLHYLHLSSSEYLSSETN
CCCCCCEEEEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
A
C
>Mature Secondary Structure 
SIKSSINPPVFFSSVILITLMVAVCAIWPTQSQDVFKTAQSWFELKAGWLYILGVAVFL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH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C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]