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The map label for this gene is 157962078

Identifier: 157962078

GI number: 157962078

Start: 2736417

End: 2737544

Strand: Reverse

Name: 157962078

Synonym: Spea_2257

Alternate gene names: NA

Gene position: 2737544-2736417 (Counterclockwise)

Preceding gene: 157962080

Following gene: 157962077

Centisome position: 52.9

GC content: 44.77

Gene sequence:

>1128_bases
ATGCGTATTACCGCGAATTTTGATAGTGGAAATATTGAAGTTATCAATCTAGATAATAAAGATGACGTACAGTTAGCGAT
CCGCCCAGATGAAGGTGGTGAGTTTTTTCAGTGGTTTAACTTTAAACTCGAAGGTGTGGTGGGTAACCAATACACGCTCA
ATATCGTTAATGCAGACAAAGCCTCTTACACTAAAGGTTGGGAAGATTACCAAGCGGTAGCGACTTACGATAGACAAAAT
TGGTTTAGACTGCCGACTCAATATAAAGACGGTAAGCTTAGTATTGAAGTTGACTTGGATTGTGATGCGATTCAAATTGC
TTACTTCGCGCCTTACAGTTACGAGCGTCACCAAGATCTTCTAGCCGCAGTACAAGTTCACCCACAAGTGAGTCTAGAGC
ACTTAGGTTTAACACTAGATGGCCGTGACATGACCCTCGTTAAGATAGGCGACGGTGATGAAGACAAAGCCAACATCTGG
ATAACCGCGCGTCAGCACCCTGGTGAGACCATGGCCGAGTGGTTAGTTGAAGGCCTGATGAACAATCTGCTTGATAGCGA
TTGCCCGACGGCTAAAGCGCTACTTGATAAGGCAAACTTCTATATCGTACCGAACATGAACCCAGACGGTAGCGCCCGTG
GTCATCTGCGTACTAACGCAGTCGGTACAAACCTTAACCGTGAATGGAAAACGCCTTCTCTTGAGAAGAGCCCTGAAGTT
CTATATGTGGTTAATAAGATGAAAGAGACTGGCGTTGATCTTTTCTATGATGTGCACGGAGATGAAGGCTTACCGTATGT
CTTCTTAGCGGGTTGCGAAGGTGTACCGGCTTTCACAGAGAAAGACGCCGCACGTCAACAAGCGTTTGTTGATGCATTAT
TGATGGCAAGCCCTGATTTTCAGGATGATTTTGGTTACGATAAAGACGAGCCAGGCCAAGCAAATCTAACCGTAGCGTCT
AACTGGGTTGCTCATACTTTTGGTTGTCTCTCAAACACCCTAGAAATGCCATTTAAAGATAATGCCAATATGCCTGACTT
AATGGCAGGCTGGTCACCAGAGCGCTGTATCTATCTTGGTGAAGCGTCATTAATTGCGATGAACGCAGTAGTTGATAAAC
TTAAGTAA

Upstream 100 bases:

>100_bases
CATTTTGGTTTATTCTATAGCGCAAAGAACGAGAGTTGGCTTGTTTGCAGCGTCAAACAGTAACAGTCACGCCGTATTAG
CAAAAGTAAAAGGAAGTGTT

Downstream 100 bases:

>100_bases
GACCAAGTGGTCAACTTAAGACGTAACCTTAAGATGTAAACAAAGAGCTAAGAGGTAGCCAATGGCTTTAGTTGATTGTC
CTAGCTGTAACAAACGCATT

Product: peptidase M14 carboxypeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRITANFDSGNIEVINLDNKDDVQLAIRPDEGGEFFQWFNFKLEGVVGNQYTLNIVNADKASYTKGWEDYQAVATYDRQN
WFRLPTQYKDGKLSIEVDLDCDAIQIAYFAPYSYERHQDLLAAVQVHPQVSLEHLGLTLDGRDMTLVKIGDGDEDKANIW
ITARQHPGETMAEWLVEGLMNNLLDSDCPTAKALLDKANFYIVPNMNPDGSARGHLRTNAVGTNLNREWKTPSLEKSPEV
LYVVNKMKETGVDLFYDVHGDEGLPYVFLAGCEGVPAFTEKDAARQQAFVDALLMASPDFQDDFGYDKDEPGQANLTVAS
NWVAHTFGCLSNTLEMPFKDNANMPDLMAGWSPERCIYLGEASLIAMNAVVDKLK

Sequences:

>Translated_375_residues
MRITANFDSGNIEVINLDNKDDVQLAIRPDEGGEFFQWFNFKLEGVVGNQYTLNIVNADKASYTKGWEDYQAVATYDRQN
WFRLPTQYKDGKLSIEVDLDCDAIQIAYFAPYSYERHQDLLAAVQVHPQVSLEHLGLTLDGRDMTLVKIGDGDEDKANIW
ITARQHPGETMAEWLVEGLMNNLLDSDCPTAKALLDKANFYIVPNMNPDGSARGHLRTNAVGTNLNREWKTPSLEKSPEV
LYVVNKMKETGVDLFYDVHGDEGLPYVFLAGCEGVPAFTEKDAARQQAFVDALLMASPDFQDDFGYDKDEPGQANLTVAS
NWVAHTFGCLSNTLEMPFKDNANMPDLMAGWSPERCIYLGEASLIAMNAVVDKLK
>Mature_375_residues
MRITANFDSGNIEVINLDNKDDVQLAIRPDEGGEFFQWFNFKLEGVVGNQYTLNIVNADKASYTKGWEDYQAVATYDRQN
WFRLPTQYKDGKLSIEVDLDCDAIQIAYFAPYSYERHQDLLAAVQVHPQVSLEHLGLTLDGRDMTLVKIGDGDEDKANIW
ITARQHPGETMAEWLVEGLMNNLLDSDCPTAKALLDKANFYIVPNMNPDGSARGHLRTNAVGTNLNREWKTPSLEKSPEV
LYVVNKMKETGVDLFYDVHGDEGLPYVFLAGCEGVPAFTEKDAARQQAFVDALLMASPDFQDDFGYDKDEPGQANLTVAS
NWVAHTFGCLSNTLEMPFKDNANMPDLMAGWSPERCIYLGEASLIAMNAVVDKLK

Specific function: Unknown

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI190194403, Length=334, Percent_Identity=29.6407185628743, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI222352158, Length=340, Percent_Identity=29.1176470588235, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI31657119, Length=303, Percent_Identity=29.3729372937294, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI170763513, Length=322, Percent_Identity=27.3291925465839, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI120444924, Length=323, Percent_Identity=28.1733746130031, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI78482633, Length=288, Percent_Identity=26.3888888888889, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI118421091, Length=289, Percent_Identity=26.643598615917, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533904, Length=364, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193202888, Length=281, Percent_Identity=25.2669039145907, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641847, Length=317, Percent_Identity=28.0757097791798, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571179, Length=313, Percent_Identity=28.4345047923323, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI161077807, Length=317, Percent_Identity=28.0757097791798, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24641845, Length=313, Percent_Identity=28.4345047923323, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24651466, Length=274, Percent_Identity=27.7372262773723, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 41973; Mature: 41973

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITANFDSGNIEVINLDNKDDVQLAIRPDEGGEFFQWFNFKLEGVVGNQYTLNIVNADK
CEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEEEEEEEECCEEEEEEEECCC
ASYTKGWEDYQAVATYDRQNWFRLPTQYKDGKLSIEVDLDCDAIQIAYFAPYSYERHQDL
CCCCCCCHHHHHHEEECCCCEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHH
LAAVQVHPQVSLEHLGLTLDGRDMTLVKIGDGDEDKANIWITARQHPGETMAEWLVEGLM
HHHEECCCCEEEEHEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
NNLLDSDCPTAKALLDKANFYIVPNMNPDGSARGHLRTNAVGTNLNREWKTPSLEKSPEV
HHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCE
LYVVNKMKETGVDLFYDVHGDEGLPYVFLAGCEGVPAFTEKDAARQQAFVDALLMASPDF
EEEEEHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
QDDFGYDKDEPGQANLTVASNWVAHTFGCLSNTLEMPFKDNANMPDLMAGWSPERCIYLG
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCEEEEC
EASLIAMNAVVDKLK
CCCEEEHHHHHHHCC
>Mature Secondary Structure
MRITANFDSGNIEVINLDNKDDVQLAIRPDEGGEFFQWFNFKLEGVVGNQYTLNIVNADK
CEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEEEEEEEECCEEEEEEEECCC
ASYTKGWEDYQAVATYDRQNWFRLPTQYKDGKLSIEVDLDCDAIQIAYFAPYSYERHQDL
CCCCCCCHHHHHHEEECCCCEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHH
LAAVQVHPQVSLEHLGLTLDGRDMTLVKIGDGDEDKANIWITARQHPGETMAEWLVEGLM
HHHEECCCCEEEEHEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
NNLLDSDCPTAKALLDKANFYIVPNMNPDGSARGHLRTNAVGTNLNREWKTPSLEKSPEV
HHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCE
LYVVNKMKETGVDLFYDVHGDEGLPYVFLAGCEGVPAFTEKDAARQQAFVDALLMASPDF
EEEEEHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
QDDFGYDKDEPGQANLTVASNWVAHTFGCLSNTLEMPFKDNANMPDLMAGWSPERCIYLG
CCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCEEEEC
EASLIAMNAVVDKLK
CCCEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8320209 [H]