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The map label for this gene is cpxR [H]

Identifier: 157962057

GI number: 157962057

Start: 2709460

End: 2710143

Strand: Reverse

Name: cpxR [H]

Synonym: Spea_2236

Alternate gene names: 157962057

Gene position: 2710143-2709460 (Counterclockwise)

Preceding gene: 157962058

Following gene: 157962055

Centisome position: 52.37

GC content: 38.6

Gene sequence:

>684_bases
ATGAAACACATTTTGCTGGTGGATAATGGTTCCACTGTTATAGGGAAATTGGCTCAGCTTCTTGCAGGCAATGATTTTAC
TGTAACCCTCGCAAACAACTTTGATGAACAACGCCTTAAAGAGGCGTCTATCTATGCCGATCTAATTTTATTATTCCTTA
ATATGTCAGATATAACTGATATTGAGCATTGTCTGCTAAAGCAAACGAAGACACCGAAAATGATATTCTCGGATACAGAT
TCTGAAGAAGACAGGATCCATGCTTATGAGCTTGGTGCCGATGACTATTTAATTCAACCTTGTAGTCAGCGTGAGCTATT
GGTTCGGATACAGACCGTGGGACGCAGATTAGAAAGCAAAAACAACTGGCCTGAGCTAAAAAGTGTTAAACCTGAAGATA
TTGACTTTGATGATAGGCTAAACACTATTTCAATTTATAAGAAATCGGTGGTTTTCACTCAGACTGAGTTTAGGCTGTTT
AAATATTTGTTCGAGAGAAAAGGTCAAGTGGTAACTAAGCAGGAACTACAACTTCGTATACTGGAGAAAGAGCTCGGAAA
ATTTGATCGTAATCTGGATATGCATATCAGTAATACCCGCCGTAAGCTGTTTGAGATGCAATTACCTAAGACTCTAATTA
ACACAGTTAGGGGAAAGGGCTACAGTTTTTCTACGATAAGCTAA

Upstream 100 bases:

>100_bases
TAGGCTCGTAGAGCTAAATCAATTTAATACAAGCGACTAGATTATTGGTTTTATTTAATGTAATCTTAATGCGAATTATT
CGTATTTGAGCTGTTAGGTA

Downstream 100 bases:

>100_bases
GTCATTAGCAAGAGTTCAAAAAAAGGGAGCCATATAGGCTCCTTTTTTTTATGAGTCGTTTTACTTAAGCAGGATAGTTG
GATCAACAAACTCAAGGTTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKHILLVDNGSTVIGKLAQLLAGNDFTVTLANNFDEQRLKEASIYADLILLFLNMSDITDIEHCLLKQTKTPKMIFSDTD
SEEDRIHAYELGADDYLIQPCSQRELLVRIQTVGRRLESKNNWPELKSVKPEDIDFDDRLNTISIYKKSVVFTQTEFRLF
KYLFERKGQVVTKQELQLRILEKELGKFDRNLDMHISNTRRKLFEMQLPKTLINTVRGKGYSFSTIS

Sequences:

>Translated_227_residues
MKHILLVDNGSTVIGKLAQLLAGNDFTVTLANNFDEQRLKEASIYADLILLFLNMSDITDIEHCLLKQTKTPKMIFSDTD
SEEDRIHAYELGADDYLIQPCSQRELLVRIQTVGRRLESKNNWPELKSVKPEDIDFDDRLNTISIYKKSVVFTQTEFRLF
KYLFERKGQVVTKQELQLRILEKELGKFDRNLDMHISNTRRKLFEMQLPKTLINTVRGKGYSFSTIS
>Mature_227_residues
MKHILLVDNGSTVIGKLAQLLAGNDFTVTLANNFDEQRLKEASIYADLILLFLNMSDITDIEHCLLKQTKTPKMIFSDTD
SEEDRIHAYELGADDYLIQPCSQRELLVRIQTVGRRLESKNNWPELKSVKPEDIDFDDRLNTISIYKKSVVFTQTEFRLF
KYLFERKGQVVTKQELQLRILEKELGKFDRNLDMHISNTRRKLFEMQLPKTLINTVRGKGYSFSTIS

Specific function: Member of a two-component regulatory system [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=35.1931330472103, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=28.2511210762332, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=27.3913043478261, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082012, Length=183, Percent_Identity=28.4153005464481, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=29.2035398230088, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.2631578947368, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787375, Length=197, Percent_Identity=25.8883248730964, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=208, Percent_Identity=30.2884615384615, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26412; Mature: 26412

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHILLVDNGSTVIGKLAQLLAGNDFTVTLANNFDEQRLKEASIYADLILLFLNMSDITD
CCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHH
IEHCLLKQTKTPKMIFSDTDSEEDRIHAYELGADDYLIQPCSQRELLVRIQTVGRRLESK
HHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCC
NNWPELKSVKPEDIDFDDRLNTISIYKKSVVFTQTEFRLFKYLFERKGQVVTKQELQLRI
CCCCCCCCCCCCCCCCCCCCCCCEEEHHEEEEEHHHHHHHHHHHHHCCCEEEHHHHHHHH
LEKELGKFDRNLDMHISNTRRKLFEMQLPKTLINTVRGKGYSFSTIS
HHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHCCCCCEECCCC
>Mature Secondary Structure
MKHILLVDNGSTVIGKLAQLLAGNDFTVTLANNFDEQRLKEASIYADLILLFLNMSDITD
CCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHH
IEHCLLKQTKTPKMIFSDTDSEEDRIHAYELGADDYLIQPCSQRELLVRIQTVGRRLESK
HHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHCC
NNWPELKSVKPEDIDFDDRLNTISIYKKSVVFTQTEFRLFKYLFERKGQVVTKQELQLRI
CCCCCCCCCCCCCCCCCCCCCCCEEEHHEEEEEHHHHHHHHHHHHHCCCEEEHHHHHHHH
LEKELGKFDRNLDMHISNTRRKLFEMQLPKTLINTVRGKGYSFSTIS
HHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]