Click here to switch to the map view.

The map label for this gene is ftsK [H]

Identifier: 157962054

GI number: 157962054

Start: 2704860

End: 2707409

Strand: Reverse

Name: ftsK [H]

Synonym: Spea_2233

Alternate gene names: 157962054

Gene position: 2707409-2704860 (Counterclockwise)

Preceding gene: 157962055

Following gene: 157962053

Centisome position: 52.32

GC content: 45.25

Gene sequence:

>2550_bases
TTGTCTAAGGGAAATAGTGTTAAAACGCTCTCTGGCGTTCAAAGATTATTGGAAGGTAGTCTTATTTTTTGTTGCATGAC
GGCGACATACGTTCTTATTGCTTTGAGCAGTTTCCATTCTTCCGATCCAGGTTGGAGTCAATCAAACTTTGATGGCGAAA
TTAATAATCTAACCGGTGCCGTAGGCGCTTGGTTGGCTGATGTTTTATTTTATTTCTTTGGTTATTGCGCCTATATCATT
CCAATCATTATCGCCTTAACAGGATGGTTGCTATTCAAGCGTACTCATAAGTTGCTTGAAATAGACTATTTTTCCGTGGG
TCTGCGTCTCATCGGATTCTTGCTTATTGTTTTCAGTCTTGCCGCGTTAGCGAGCATGAACGCCAATGGTATCTATGGTT
TCTCTGCTGGTGGGGTTGCAGGTGACGTCATTGGTCAGGCAATGCTGCCTTACTTTAATAGTCTGGGTACCACATTATTA
TTACTCTGCTTTGTTGGCGCAGGTTTTACGTTACTCACTGGCATTAGCTGGTTAACCGTTGTCGACTTAACTGGTTACGC
TACAATCTGGTTTTTTAGAGCCCTTAAAGAACTTCCTAACAAATTTAAGCCAGAAATGGGTGACACCGAAGACACTAGAG
GCTTCTTGTCAGTGGTTGAGCGTTTTAAAGAGCGCCGTAATACCGCCGCAGGTGAAGATGATGAAGAGTCAAACGAAGAT
AGCCCAGCGGCCAAAACGGTCACAGTTAACAAAGAAAAGCCTAAGGTTGACAGCGTTCAACCTAGGATTGAACCCCAAAT
ATTTGAACGTTCTGAAGACTTTGTACAAGCTGCAGCGCCAATCAATATCGACCCACAGATGATTGAGCCACACATTGCCG
CGCCATGGGTCAATGATGAGGCTGACGATGTTGAGTTAATTGATACTGATAACAAAGTATCAAGCGAGCCTGTTTCAGTG
AGTAAGCGTAATGAACAAGACAAAGCCAAAGTTGTCGATGGGATAGTGGTTCTGCCTGGACAAGAACTTGAGCAAGAGCG
CCCACCTATGGCGCCTTTACCTTGTATTTCCTTATTAGATGTGCCTAATCGCACCACAAATCCGATTAGCCAAGAAGAGC
TCGAGCAGATTGGTAAACTAGTCGAAGTTAAGTTAGCCGATTTCAACATTACCGCTAATGTTGTAGGGGTGTATCCAGGT
CCGGTGGTGACTCGTTTCGAGCTTGAACTGGCTCCAGGCGTGAAGGCTTCAAAAATCACAAATCTATCAAAGGATTTGGC
ACGCTCTCTACTGGCTGAAAATGTGCGGGTTGTCGAAGTGATCCCTGGTAAGGCTTATGTGGGATTAGAGTTACCAAACA
AGTTCCGCGAAACTGTGTTTATGCGCGATGTACTCGATTGTGAAGATTTTAGAGAAAACCCATCCCACTTAAGCATGGTG
TTAGGTGCCGATATCGGTGGTAAACCGGTTGTCGTTGACTTGGGTAAGATGCCGCATCTTCTTGTTGCTGGTACTACAGG
CTCGGGTAAGTCGGTTGGCGTTAACGTGATGATCACCAGCTTACTCTATAAGTCTGGCCCTGATGACGTTCGCTTCATTA
TGATCGACCCTAAAATGCTGGAGTTATCGGTTTATGAAGGGATTCCACATCTTCTTTGTGAAGTAGTAACCGATATGAAG
GAAGCTGCTAATGCACTGCGTTGGTGCGTTGGGGAGATGGAGCGTCGTTATAAGCTAATGTCAGCCTTAGGGGTGCGAAA
CCTTAAAGGCTATAACGCTAAGATTAAACAAGCAAAAGAGTCAGGTGAACCTATCTACGATCCACTTTGGAAGTCTTCAG
ATAGTATGGAGCCTGAAGCGCCTGAGCTGGATAAGTTGCCTTCTATTGTTGTTGTCGTCGATGAGTTTGCCGATATGATG
ATGATCGTCGGTAAAAAAGTAGAAGAACTCATAGCTCGAATTGCTCAAAAGGCTCGTGCGGCTGGTATTCACTTGATTTT
GGCGACTCAGAGACCGTCAGTTGATGTGATAACTGGCTTGATTAAAGCTAACATTCCAACACGTATGGCGTTTCAAGTAT
CATCGCGAATCGATTCTAGAACTATCTTAGATCAGCAGGGGGCTGAAACCTTGCTAGGTATGGGTGACATGCTCTATTTA
CCACCTGGTACCAGTATTCCTATGCGAGTACACGGCGCATTTATTGACGATCATGAAGTTCATAAGGTGGTAGCCGATTG
GCATGCGCGTGGTAAGCCACAATATATCGAAGAAATTTTACAAGGTTCAGCAGAAGGCGAGCAGGTATTATTACCCGGTG
AAGCTAGCGACAGTGAAGAAGAGGTAGACGCATTATATGATGAAGCGGTCGCCTTCGTTACTCAAACTCGTCGTGGCTCA
ATCTCTAGCGTCCAACGTAAGTTCAAGATTGGTTATAACCGCGCGGCGCGAATCATCGAGCAGATGGAACTTCAAGGCGT
CGTCAGTGCCCAAGGGCATAACGGCAATCGTGAGGTACTAGCGCCACCACCGCCAAAAGATTACGTATAA

Upstream 100 bases:

>100_bases
AATAAATATTCAGTCGTGCTTAGAAGTCGCAAACGCTGCATAAAGTCTTAATTTCTGGTATCTTGTCCTTAATTGAGGTT
TTTTTAGTGTAGGTTTTCCA

Downstream 100 bases:

>100_bases
AACAGTTTGAATACGACTAATTAGATTTAGCGTTAAGCCTAAATATGGCTTTTCTCGGAGAGTATAATGAAAAAGATTTT
CACGATAGCAGCCTTGAGTC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 849; Mature: 848

Protein sequence:

>849_residues
MSKGNSVKTLSGVQRLLEGSLIFCCMTATYVLIALSSFHSSDPGWSQSNFDGEINNLTGAVGAWLADVLFYFFGYCAYII
PIIIALTGWLLFKRTHKLLEIDYFSVGLRLIGFLLIVFSLAALASMNANGIYGFSAGGVAGDVIGQAMLPYFNSLGTTLL
LLCFVGAGFTLLTGISWLTVVDLTGYATIWFFRALKELPNKFKPEMGDTEDTRGFLSVVERFKERRNTAAGEDDEESNED
SPAAKTVTVNKEKPKVDSVQPRIEPQIFERSEDFVQAAAPINIDPQMIEPHIAAPWVNDEADDVELIDTDNKVSSEPVSV
SKRNEQDKAKVVDGIVVLPGQELEQERPPMAPLPCISLLDVPNRTTNPISQEELEQIGKLVEVKLADFNITANVVGVYPG
PVVTRFELELAPGVKASKITNLSKDLARSLLAENVRVVEVIPGKAYVGLELPNKFRETVFMRDVLDCEDFRENPSHLSMV
LGADIGGKPVVVDLGKMPHLLVAGTTGSGKSVGVNVMITSLLYKSGPDDVRFIMIDPKMLELSVYEGIPHLLCEVVTDMK
EAANALRWCVGEMERRYKLMSALGVRNLKGYNAKIKQAKESGEPIYDPLWKSSDSMEPEAPELDKLPSIVVVVDEFADMM
MIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSRIDSRTILDQQGAETLLGMGDMLYL
PPGTSIPMRVHGAFIDDHEVHKVVADWHARGKPQYIEEILQGSAEGEQVLLPGEASDSEEEVDALYDEAVAFVTQTRRGS
ISSVQRKFKIGYNRAARIIEQMELQGVVSAQGHNGNREVLAPPPPKDYV

Sequences:

>Translated_849_residues
MSKGNSVKTLSGVQRLLEGSLIFCCMTATYVLIALSSFHSSDPGWSQSNFDGEINNLTGAVGAWLADVLFYFFGYCAYII
PIIIALTGWLLFKRTHKLLEIDYFSVGLRLIGFLLIVFSLAALASMNANGIYGFSAGGVAGDVIGQAMLPYFNSLGTTLL
LLCFVGAGFTLLTGISWLTVVDLTGYATIWFFRALKELPNKFKPEMGDTEDTRGFLSVVERFKERRNTAAGEDDEESNED
SPAAKTVTVNKEKPKVDSVQPRIEPQIFERSEDFVQAAAPINIDPQMIEPHIAAPWVNDEADDVELIDTDNKVSSEPVSV
SKRNEQDKAKVVDGIVVLPGQELEQERPPMAPLPCISLLDVPNRTTNPISQEELEQIGKLVEVKLADFNITANVVGVYPG
PVVTRFELELAPGVKASKITNLSKDLARSLLAENVRVVEVIPGKAYVGLELPNKFRETVFMRDVLDCEDFRENPSHLSMV
LGADIGGKPVVVDLGKMPHLLVAGTTGSGKSVGVNVMITSLLYKSGPDDVRFIMIDPKMLELSVYEGIPHLLCEVVTDMK
EAANALRWCVGEMERRYKLMSALGVRNLKGYNAKIKQAKESGEPIYDPLWKSSDSMEPEAPELDKLPSIVVVVDEFADMM
MIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSRIDSRTILDQQGAETLLGMGDMLYL
PPGTSIPMRVHGAFIDDHEVHKVVADWHARGKPQYIEEILQGSAEGEQVLLPGEASDSEEEVDALYDEAVAFVTQTRRGS
ISSVQRKFKIGYNRAARIIEQMELQGVVSAQGHNGNREVLAPPPPKDYV
>Mature_848_residues
SKGNSVKTLSGVQRLLEGSLIFCCMTATYVLIALSSFHSSDPGWSQSNFDGEINNLTGAVGAWLADVLFYFFGYCAYIIP
IIIALTGWLLFKRTHKLLEIDYFSVGLRLIGFLLIVFSLAALASMNANGIYGFSAGGVAGDVIGQAMLPYFNSLGTTLLL
LCFVGAGFTLLTGISWLTVVDLTGYATIWFFRALKELPNKFKPEMGDTEDTRGFLSVVERFKERRNTAAGEDDEESNEDS
PAAKTVTVNKEKPKVDSVQPRIEPQIFERSEDFVQAAAPINIDPQMIEPHIAAPWVNDEADDVELIDTDNKVSSEPVSVS
KRNEQDKAKVVDGIVVLPGQELEQERPPMAPLPCISLLDVPNRTTNPISQEELEQIGKLVEVKLADFNITANVVGVYPGP
VVTRFELELAPGVKASKITNLSKDLARSLLAENVRVVEVIPGKAYVGLELPNKFRETVFMRDVLDCEDFRENPSHLSMVL
GADIGGKPVVVDLGKMPHLLVAGTTGSGKSVGVNVMITSLLYKSGPDDVRFIMIDPKMLELSVYEGIPHLLCEVVTDMKE
AANALRWCVGEMERRYKLMSALGVRNLKGYNAKIKQAKESGEPIYDPLWKSSDSMEPEAPELDKLPSIVVVVDEFADMMM
IVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSRIDSRTILDQQGAETLLGMGDMLYLP
PGTSIPMRVHGAFIDDHEVHKVVADWHARGKPQYIEEILQGSAEGEQVLLPGEASDSEEEVDALYDEAVAFVTQTRRGSI
SSVQRKFKIGYNRAARIIEQMELQGVVSAQGHNGNREVLAPPPPKDYV

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=497, Percent_Identity=70.8249496981891, Blast_Score=709, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 93158; Mature: 93027

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGNSVKTLSGVQRLLEGSLIFCCMTATYVLIALSSFHSSDPGWSQSNFDGEINNLTGA
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
VGAWLADVLFYFFGYCAYIIPIIIALTGWLLFKRTHKLLEIDYFSVGLRLIGFLLIVFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHH
AALASMNANGIYGFSAGGVAGDVIGQAMLPYFNSLGTTLLLLCFVGAGFTLLTGISWLTV
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VDLTGYATIWFFRALKELPNKFKPEMGDTEDTRGFLSVVERFKERRNTAAGEDDEESNED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SPAAKTVTVNKEKPKVDSVQPRIEPQIFERSEDFVQAAAPINIDPQMIEPHIAAPWVNDE
CCCCEEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCCHHHCCCCCCCCCCCCC
ADDVELIDTDNKVSSEPVSVSKRNEQDKAKVVDGIVVLPGQELEQERPPMAPLPCISLLD
CCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCEEECCCHHHHHCCCCCCCCCHHHHHC
VPNRTTNPISQEELEQIGKLVEVKLADFNITANVVGVYPGPVVTRFELELAPGVKASKIT
CCCCCCCCCCHHHHHHHHHHHEEEEECEEEEEEEEEECCCCEEEEEEEEECCCCCHHHHH
NLSKDLARSLLAENVRVVEVIPGKAYVGLELPNKFRETVFMRDVLDCEDFRENPSHLSMV
HHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCHHHHHCCHHHEEEE
LGADIGGKPVVVDLGKMPHLLVAGTTGSGKSVGVNVMITSLLYKSGPDDVRFIMIDPKML
EECCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCEE
ELSVYEGIPHLLCEVVTDMKEAANALRWCVGEMERRYKLMSALGVRNLKGYNAKIKQAKE
EHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SGEPIYDPLWKSSDSMEPEAPELDKLPSIVVVVDEFADMMMIVGKKVEELIARIAQKARA
CCCCCCCHHCCCCCCCCCCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSRIDSRTILDQQGAETLLGMGDMLYL
CCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCHHHHHCCCCEEEE
PPGTSIPMRVHGAFIDDHEVHKVVADWHARGKPQYIEEILQGSAEGEQVLLPGEASDSEE
CCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCCHH
EVDALYDEAVAFVTQTRRGSISSVQRKFKIGYNRAARIIEQMELQGVVSAQGHNGNREVL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCEE
APPPPKDYV
CCCCCCCCC
>Mature Secondary Structure 
SKGNSVKTLSGVQRLLEGSLIFCCMTATYVLIALSSFHSSDPGWSQSNFDGEINNLTGA
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
VGAWLADVLFYFFGYCAYIIPIIIALTGWLLFKRTHKLLEIDYFSVGLRLIGFLLIVFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHH
AALASMNANGIYGFSAGGVAGDVIGQAMLPYFNSLGTTLLLLCFVGAGFTLLTGISWLTV
HHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VDLTGYATIWFFRALKELPNKFKPEMGDTEDTRGFLSVVERFKERRNTAAGEDDEESNED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SPAAKTVTVNKEKPKVDSVQPRIEPQIFERSEDFVQAAAPINIDPQMIEPHIAAPWVNDE
CCCCEEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCCHHHCCCCCCCCCCCCC
ADDVELIDTDNKVSSEPVSVSKRNEQDKAKVVDGIVVLPGQELEQERPPMAPLPCISLLD
CCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCEEECCCHHHHHCCCCCCCCCHHHHHC
VPNRTTNPISQEELEQIGKLVEVKLADFNITANVVGVYPGPVVTRFELELAPGVKASKIT
CCCCCCCCCCHHHHHHHHHHHEEEEECEEEEEEEEEECCCCEEEEEEEEECCCCCHHHHH
NLSKDLARSLLAENVRVVEVIPGKAYVGLELPNKFRETVFMRDVLDCEDFRENPSHLSMV
HHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCHHHHHCCHHHEEEE
LGADIGGKPVVVDLGKMPHLLVAGTTGSGKSVGVNVMITSLLYKSGPDDVRFIMIDPKML
EECCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCEE
ELSVYEGIPHLLCEVVTDMKEAANALRWCVGEMERRYKLMSALGVRNLKGYNAKIKQAKE
EHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SGEPIYDPLWKSSDSMEPEAPELDKLPSIVVVVDEFADMMMIVGKKVEELIARIAQKARA
CCCCCCCHHCCCCCCCCCCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSRIDSRTILDQQGAETLLGMGDMLYL
CCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCHHHHHCCCCEEEE
PPGTSIPMRVHGAFIDDHEVHKVVADWHARGKPQYIEEILQGSAEGEQVLLPGEASDSEE
CCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCCHH
EVDALYDEAVAFVTQTRRGSISSVQRKFKIGYNRAARIIEQMELQGVVSAQGHNGNREVL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCEE
APPPPKDYV
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]