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The map label for this gene is mdtA [H]

Identifier: 157961999

GI number: 157961999

Start: 2637518

End: 2638711

Strand: Reverse

Name: mdtA [H]

Synonym: Spea_2178

Alternate gene names: 157961999

Gene position: 2638711-2637518 (Counterclockwise)

Preceding gene: 157962000

Following gene: 157961998

Centisome position: 50.99

GC content: 46.31

Gene sequence:

>1194_bases
GTGGCTACCAAAAAACAGATCATTTTACCAATGGCTGTCATCGCTATCGGCGTGGCAGGATTTATTGGCATATCGGCATT
GAAAAAGCCGCCAGAAGAGAAGGAAGAGCTCGATACCACCCCCTTGGTCTCTGTCGAGGCAGTCCAAATTAATCCGATGA
GTTTTGCAGTCAGCTCCTATGGCGTAGTTAATGCGAAATATGAGACGGAACTAGTTTCCCAGCTAAACGGCGAGATCGTT
TTCTTATCTGAAAAATTTGTACGCGGCGGCTTTGTCAAAAAAGGCGATATCCTTGCCAAAATAGATCCTAGCGATTACGA
ATCAGCACTGATTGATGCGCAGGCGAATATGGCTTCGGCGCGAGCGACATTAGTGCAAGAGAAAGCGTACGGTAAGGTTG
CCGAAGAGGAATGGAAACGCATTAAGAATGGTGTACCGACTGAACTGAGTCTTAGAAAGCCTCAATTAGCGCAAGAGATT
GCCAAGTTAAACTCTTCTGAAGCAGGGCTTAAACGTGCTAAACGTAATCTTGAGCGCACCTTAATTAAAGCGCCATACGA
TGCTCTAATCGAGGCGCGTAACATAGGTTTAGGCTCATACGTCAGCATGGGCACACCATTAGGTAAGGTGTTAAGTACCG
CAGAAGCTGAGATCCGTCTTCCTATTGCAGATAAGGAACTGCAGTTTTTAGATGACAAAGGCAAACATGCACAAGTGGTA
TTGAAAGGTGAATTCGCAGGTAAGACTCAAGAATGGCCTGCTACTGTGGTGCGTAGTGAGGGCGTGATTGATAATCGCAG
TCGCATGACCTACTTGGTCGCTGAAGTAACCGATCCTTACGGACTAAAGTCAAACAACAATGAATTACGCTATGGCACTT
ATGTTACTGCAACAATCGATGGTACTCATGCGGGTTTAGTCGCAGAACTGCCGCGCCACCTTGTGATCAACAATCAGGTC
GCGGTGCTAGATGATGAGGGCAAGCTTAGATACAAAGACATCACCATTCTACGTCAAGTCGGCTCTAAGGTTATCGTCTC
CGATGGTCTCGAATCAGGCATGAATGTGATCACCTCTGCTTTAGATTACCCCATCGAAGGCATGGAGCTAGCTCTGCCTG
AAGACAAGTTGTTACGTGATGAAGAAAATCCTGAACAGCAACCTACGCAAATCGCGATGGAAGATAAGGATTAA

Upstream 100 bases:

>100_bases
TGTATTCAAAATTCTAATTAGATTACTCATCGTTATTGCTGCCAAAGCAGTAAAAAGATTGCTATTGAGTGCAAATTTGC
TTCAACAAGAGGACGTGTTT

Downstream 100 bases:

>100_bases
TTCATGATAGATACTAACAAAGGCATCATCGCTTGGTTTGCACGCAATAGCGTTGCCGCAAACTTGCTAATGATTATTAT
CTTGCTGGGTGGACTGTTAA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MATKKQIILPMAVIAIGVAGFIGISALKKPPEEKEELDTTPLVSVEAVQINPMSFAVSSYGVVNAKYETELVSQLNGEIV
FLSEKFVRGGFVKKGDILAKIDPSDYESALIDAQANMASARATLVQEKAYGKVAEEEWKRIKNGVPTELSLRKPQLAQEI
AKLNSSEAGLKRAKRNLERTLIKAPYDALIEARNIGLGSYVSMGTPLGKVLSTAEAEIRLPIADKELQFLDDKGKHAQVV
LKGEFAGKTQEWPATVVRSEGVIDNRSRMTYLVAEVTDPYGLKSNNNELRYGTYVTATIDGTHAGLVAELPRHLVINNQV
AVLDDEGKLRYKDITILRQVGSKVIVSDGLESGMNVITSALDYPIEGMELALPEDKLLRDEENPEQQPTQIAMEDKD

Sequences:

>Translated_397_residues
MATKKQIILPMAVIAIGVAGFIGISALKKPPEEKEELDTTPLVSVEAVQINPMSFAVSSYGVVNAKYETELVSQLNGEIV
FLSEKFVRGGFVKKGDILAKIDPSDYESALIDAQANMASARATLVQEKAYGKVAEEEWKRIKNGVPTELSLRKPQLAQEI
AKLNSSEAGLKRAKRNLERTLIKAPYDALIEARNIGLGSYVSMGTPLGKVLSTAEAEIRLPIADKELQFLDDKGKHAQVV
LKGEFAGKTQEWPATVVRSEGVIDNRSRMTYLVAEVTDPYGLKSNNNELRYGTYVTATIDGTHAGLVAELPRHLVINNQV
AVLDDEGKLRYKDITILRQVGSKVIVSDGLESGMNVITSALDYPIEGMELALPEDKLLRDEENPEQQPTQIAMEDKD
>Mature_396_residues
ATKKQIILPMAVIAIGVAGFIGISALKKPPEEKEELDTTPLVSVEAVQINPMSFAVSSYGVVNAKYETELVSQLNGEIVF
LSEKFVRGGFVKKGDILAKIDPSDYESALIDAQANMASARATLVQEKAYGKVAEEEWKRIKNGVPTELSLRKPQLAQEIA
KLNSSEAGLKRAKRNLERTLIKAPYDALIEARNIGLGSYVSMGTPLGKVLSTAEAEIRLPIADKELQFLDDKGKHAQVVL
KGEFAGKTQEWPATVVRSEGVIDNRSRMTYLVAEVTDPYGLKSNNNELRYGTYVTATIDGTHAGLVAELPRHLVINNQVA
VLDDEGKLRYKDITILRQVGSKVIVSDGLESGMNVITSALDYPIEGMELALPEDKLLRDEENPEQQPTQIAMEDKD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=388, Percent_Identity=25.5154639175258, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43466; Mature: 43335

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKKQIILPMAVIAIGVAGFIGISALKKPPEEKEELDTTPLVSVEAVQINPMSFAVSSY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEEECCCEEEHHCC
GVVNAKYETELVSQLNGEIVFLSEKFVRGGFVKKGDILAKIDPSDYESALIDAQANMASA
CEEECHHHHHHHHHHCCCEEEEEHHHHCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHH
RATLVQEKAYGKVAEEEWKRIKNGVPTELSLRKPQLAQEIAKLNSSEAGLKRAKRNLERT
HHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LIKAPYDALIEARNIGLGSYVSMGTPLGKVLSTAEAEIRLPIADKELQFLDDKGKHAQVV
HHHCCHHHHHHHHCCCCCCHHHCCCCHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEEEE
LKGEFAGKTQEWPATVVRSEGVIDNRSRMTYLVAEVTDPYGLKSNNNELRYGTYVTATID
EEECCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEC
GTHAGLVAELPRHLVINNQVAVLDDEGKLRYKDITILRQVGSKVIVSDGLESGMNVITSA
CCCCCHHHHCCHHEEECCCEEEEECCCCEEEHHHHHHHHHCCEEEECCCHHHHHHHHHHH
LDYPIEGMELALPEDKLLRDEENPEQQPTQIAMEDKD
HCCCCCCEEEECCCHHHHCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure 
ATKKQIILPMAVIAIGVAGFIGISALKKPPEEKEELDTTPLVSVEAVQINPMSFAVSSY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEEECCCEEEHHCC
GVVNAKYETELVSQLNGEIVFLSEKFVRGGFVKKGDILAKIDPSDYESALIDAQANMASA
CEEECHHHHHHHHHHCCCEEEEEHHHHCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHH
RATLVQEKAYGKVAEEEWKRIKNGVPTELSLRKPQLAQEIAKLNSSEAGLKRAKRNLERT
HHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LIKAPYDALIEARNIGLGSYVSMGTPLGKVLSTAEAEIRLPIADKELQFLDDKGKHAQVV
HHHCCHHHHHHHHCCCCCCHHHCCCCHHHHHHCCCCEEEECCCCCHHHHHCCCCCEEEEE
LKGEFAGKTQEWPATVVRSEGVIDNRSRMTYLVAEVTDPYGLKSNNNELRYGTYVTATID
EEECCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEEEC
GTHAGLVAELPRHLVINNQVAVLDDEGKLRYKDITILRQVGSKVIVSDGLESGMNVITSA
CCCCCHHHHCCHHEEECCCEEEEECCCCEEEHHHHHHHHHCCEEEECCCHHHHHHHHHHH
LDYPIEGMELALPEDKLLRDEENPEQQPTQIAMEDKD
HCCCCCCEEEECCCHHHHCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA