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The map label for this gene is pssA [H]

Identifier: 157961906

GI number: 157961906

Start: 2524740

End: 2526080

Strand: Direct

Name: pssA [H]

Synonym: Spea_2085

Alternate gene names: 157961906

Gene position: 2524740-2526080 (Clockwise)

Preceding gene: 157961905

Following gene: 157961907

Centisome position: 48.79

GC content: 42.21

Gene sequence:

>1341_bases
ATGGTCAGCACTATTAAGGAGAGAGCCTTGCTGAGTAAGCTAGGTGGCATACCGCTACAACCAGATTCGCTTTCATGGCT
ATTAACGCCTAAAGCGTTAAAAGCTGAATTGTTATCTCGAATTGCAACTGCAACGCATTCTATCTATATCGCAGCACTCT
ATTTAGAAGATGACGAAGCAGGTAGAGAAATTATTGCCGCTTTGATAGCGGCGAAAAACCAGAACCCTCAACTCGATGTC
AAAGTGCTTGTTGATTTTCATCGTGCCCGTCGTGGTCTTATTGGCCATAAAGGTGACAGTGGCAATTACTTTATGTATCG
CAAGGTCATTGAGGCTGCAGAGCACCCTATCGATATTTTAGGGGTACCGGTTAAGTCCCGTGAGTTTATGGGCGTGCTGC
ACCTTAAGGGCTTCATTATTGATGACACTGTTATCTTTAGTGGCGCAAGCTTAAATAACATCTATCTTCACCAAGATGAT
AAGTATCGTTTTGACCGTTATCATGTGATTGAATCTGCAGAGCTTGCTCGCAGTATGCGTGAAATGATCCAAACTTATTT
GGTTAATGATGTTGCAGTTAGCTCTTTGACTCAGCCTAAAGAAACCGAGCAGCTGCCAACCAAAGCAGAGGTTAGCAGCC
TCAAGCATCGCTTATCAAAAGCTGAGTATAAATATACTGAGACTCGAATTGGCAATCGCGTTACGCCGTTAGTGGGTCTT
GGGCGTAAGAAAAACAAGTTAAACAGGGTGATTGTAGCAATGGTAGAGGAGTCTCAAAACTCACTCTTTATTTGCACTCC
CTATTTTAATCCGCCCTATATCTTAGTTCGAGCATTAGCTAAGCATCTGCGTAATGGTAAGAAGATAGATATCGTTGTGG
GTGATAAAACCTCAAACGATTTTTACATTCCACCAGAGGAAGAGTTCTCTACCATTGGCGCACTGCCTTATATGTATGAG
CAGTCGCTTAGAAAATTTGCAAAACGCCAGCAATGGGCGATTGAGAATGGTCAGTTAAACATTCATCTATGGAAAGATGG
CCGTAACAGCTTCCATTTAAAAGGGATCAGCGCCGACAGTAATCGCCATATGATCACTGGCAGCAATCTAAACCCAAGAG
CTTGGGCGTTAGATTTGGAAAATGGCTTATTATTGCAAGACGATAATGAATGCTGGAAAGAGAAGTTTGAGCAAGAACAA
GCGCACATTCTTGAACATACTGAGCGTCTGTTTCATTATAGCCAGATTGAAACGCTAAATAATTATCCTGCGCCAGTGCG
TAAGATCATGAAGCGAATTAAGCGTTTGAAAGCAGATTTTCTGTTAAGACGTATACTTTAA

Upstream 100 bases:

>100_bases
GCACAAACGGTTATCCGTGAAGCCTTACTAAAGGTTTATCCGGGGCTAAAACATGTGATTGTCATGTTTAGAGAGCTTGA
ACCGAGCACTTATTATAAAG

Downstream 100 bases:

>100_bases
GTATGTCGATTGACTAACGATTAAAAGCCTGCCGATGAGTAGGCTTTTTCTTTTTAAAACTTATCCACTCAGATAGTTAT
AATTTCACATAGACACTATT

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MVSTIKERALLSKLGGIPLQPDSLSWLLTPKALKAELLSRIATATHSIYIAALYLEDDEAGREIIAALIAAKNQNPQLDV
KVLVDFHRARRGLIGHKGDSGNYFMYRKVIEAAEHPIDILGVPVKSREFMGVLHLKGFIIDDTVIFSGASLNNIYLHQDD
KYRFDRYHVIESAELARSMREMIQTYLVNDVAVSSLTQPKETEQLPTKAEVSSLKHRLSKAEYKYTETRIGNRVTPLVGL
GRKKNKLNRVIVAMVEESQNSLFICTPYFNPPYILVRALAKHLRNGKKIDIVVGDKTSNDFYIPPEEEFSTIGALPYMYE
QSLRKFAKRQQWAIENGQLNIHLWKDGRNSFHLKGISADSNRHMITGSNLNPRAWALDLENGLLLQDDNECWKEKFEQEQ
AHILEHTERLFHYSQIETLNNYPAPVRKIMKRIKRLKADFLLRRIL

Sequences:

>Translated_446_residues
MVSTIKERALLSKLGGIPLQPDSLSWLLTPKALKAELLSRIATATHSIYIAALYLEDDEAGREIIAALIAAKNQNPQLDV
KVLVDFHRARRGLIGHKGDSGNYFMYRKVIEAAEHPIDILGVPVKSREFMGVLHLKGFIIDDTVIFSGASLNNIYLHQDD
KYRFDRYHVIESAELARSMREMIQTYLVNDVAVSSLTQPKETEQLPTKAEVSSLKHRLSKAEYKYTETRIGNRVTPLVGL
GRKKNKLNRVIVAMVEESQNSLFICTPYFNPPYILVRALAKHLRNGKKIDIVVGDKTSNDFYIPPEEEFSTIGALPYMYE
QSLRKFAKRQQWAIENGQLNIHLWKDGRNSFHLKGISADSNRHMITGSNLNPRAWALDLENGLLLQDDNECWKEKFEQEQ
AHILEHTERLFHYSQIETLNNYPAPVRKIMKRIKRLKADFLLRRIL
>Mature_446_residues
MVSTIKERALLSKLGGIPLQPDSLSWLLTPKALKAELLSRIATATHSIYIAALYLEDDEAGREIIAALIAAKNQNPQLDV
KVLVDFHRARRGLIGHKGDSGNYFMYRKVIEAAEHPIDILGVPVKSREFMGVLHLKGFIIDDTVIFSGASLNNIYLHQDD
KYRFDRYHVIESAELARSMREMIQTYLVNDVAVSSLTQPKETEQLPTKAEVSSLKHRLSKAEYKYTETRIGNRVTPLVGL
GRKKNKLNRVIVAMVEESQNSLFICTPYFNPPYILVRALAKHLRNGKKIDIVVGDKTSNDFYIPPEEEFSTIGALPYMYE
QSLRKFAKRQQWAIENGQLNIHLWKDGRNSFHLKGISADSNRHMITGSNLNPRAWALDLENGLLLQDDNECWKEKFEQEQ
AHILEHTERLFHYSQIETLNNYPAPVRKIMKRIKRLKADFLLRRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=426, Percent_Identity=44.131455399061, Blast_Score=359, Evalue=1e-100,
Organism=Drosophila melanogaster, GI28572961, Length=466, Percent_Identity=23.175965665236, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 51145; Mature: 51145

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTIKERALLSKLGGIPLQPDSLSWLLTPKALKAELLSRIATATHSIYIAALYLEDDEA
CCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEEEEECCHH
GREIIAALIAAKNQNPQLDVKVLVDFHRARRGLIGHKGDSGNYFMYRKVIEAAEHPIDIL
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEE
GVPVKSREFMGVLHLKGFIIDDTVIFSGASLNNIYLHQDDKYRFDRYHVIESAELARSMR
ECCCCCHHHHEEEECCCEEEECEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
EMIQTYLVNDVAVSSLTQPKETEQLPTKAEVSSLKHRLSKAEYKYTETRIGNRVTPLVGL
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
GRKKNKLNRVIVAMVEESQNSLFICTPYFNPPYILVRALAKHLRNGKKIDIVVGDKTSND
CCCHHHHHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCC
FYIPPEEEFSTIGALPYMYEQSLRKFAKRQQWAIENGQLNIHLWKDGRNSFHLKGISADS
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCEEECCEEEEEEEECCCCEEEEEEECCCC
NRHMITGSNLNPRAWALDLENGLLLQDDNECWKEKFEQEQAHILEHTERLFHYSQIETLN
CCEEEECCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NYPAPVRKIMKRIKRLKADFLLRRIL
CCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVSTIKERALLSKLGGIPLQPDSLSWLLTPKALKAELLSRIATATHSIYIAALYLEDDEA
CCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEEEEECCHH
GREIIAALIAAKNQNPQLDVKVLVDFHRARRGLIGHKGDSGNYFMYRKVIEAAEHPIDIL
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEE
GVPVKSREFMGVLHLKGFIIDDTVIFSGASLNNIYLHQDDKYRFDRYHVIESAELARSMR
ECCCCCHHHHEEEECCCEEEECEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
EMIQTYLVNDVAVSSLTQPKETEQLPTKAEVSSLKHRLSKAEYKYTETRIGNRVTPLVGL
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
GRKKNKLNRVIVAMVEESQNSLFICTPYFNPPYILVRALAKHLRNGKKIDIVVGDKTSND
CCCHHHHHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCC
FYIPPEEEFSTIGALPYMYEQSLRKFAKRQQWAIENGQLNIHLWKDGRNSFHLKGISADS
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCEEECCEEEEEEEECCCCEEEEEEECCCC
NRHMITGSNLNPRAWALDLENGLLLQDDNECWKEKFEQEQAHILEHTERLFHYSQIETLN
CCEEEECCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NYPAPVRKIMKRIKRLKADFLLRRIL
CCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]