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The map label for this gene is can [H]

Identifier: 157961809

GI number: 157961809

Start: 2412852

End: 2413466

Strand: Reverse

Name: can [H]

Synonym: Spea_1988

Alternate gene names: 157961809

Gene position: 2413466-2412852 (Counterclockwise)

Preceding gene: 157961810

Following gene: 157961808

Centisome position: 46.64

GC content: 42.44

Gene sequence:

>615_bases
ATGAAACTACTAAAACCGCTTTTTGAAAATAATCGCCGTTGGGCAGGCCGGATCTTAGAAGAAGATCCTCAATTCTTCGA
ACAGCTCGCTAAGCAACAGAGTCCTGAATACCTCTGGATAGGTTGCTCTGATAGTCGAGTCCCTTCTAATCAAATCATTG
ATTTGATGCCAGGCGAAGTATTTGTTCATCGAAACATTGCCAATATGGTTATCCATACCGATTTAAACTGTTTATCTGTT
CTCCAGTATGCCGTTGAGGTGCTAAAAGTTAAGCACATCATGGTTGTTGGGCACTACGGCTGTGGTGGAATTAAAGCCTC
GATGGGGAAAGAGCGACTTGGCCTTATCGATAACTGGCTCGGTCATATTCGTGACATTTATCGCTTACATAGAGCCGATC
TTGACAATATGGATGAGTCTGAGCGTTTCGACCGTTTATGCGAATTAAATGTCATGGAACAAGTAGCAAATGTCACCGAT
ACCACCATAGTTCAAGAGGCTTGGGCTCGTGGTCAAGATGTTGCCATTCATGGTTGGATTTATAGCGTAGAGAACGGTTT
ACTCTCCGATTTAGATGTTACCGTAAACAAAGATACGGAAAAAGAAAATAGCTAA

Upstream 100 bases:

>100_bases
ATTACTTCTCTATAGTACTGAATAGACCAGCAGAGCTAAGTTTCAGTGATAAACTTAGCCTGTATTGAGATTTTCTTAAC
TGACCGAATATAAGAGCAGA

Downstream 100 bases:

>100_bases
GACGCTATTAACTCAATGCAACTTATTAAGGGCTAGCTCAGTCATTGTACTGAACTAGCCCTTTTCTCATCATGCTCATT
GCGATTACGTTAACAAACAT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKLLKPLFENNRRWAGRILEEDPQFFEQLAKQQSPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAVEVLKVKHIMVVGHYGCGGIKASMGKERLGLIDNWLGHIRDIYRLHRADLDNMDESERFDRLCELNVMEQVANVTD
TTIVQEAWARGQDVAIHGWIYSVENGLLSDLDVTVNKDTEKENS

Sequences:

>Translated_204_residues
MKLLKPLFENNRRWAGRILEEDPQFFEQLAKQQSPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAVEVLKVKHIMVVGHYGCGGIKASMGKERLGLIDNWLGHIRDIYRLHRADLDNMDESERFDRLCELNVMEQVANVTD
TTIVQEAWARGQDVAIHGWIYSVENGLLSDLDVTVNKDTEKENS
>Mature_204_residues
MKLLKPLFENNRRWAGRILEEDPQFFEQLAKQQSPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAVEVLKVKHIMVVGHYGCGGIKASMGKERLGLIDNWLGHIRDIYRLHRADLDNMDESERFDRLCELNVMEQVANVTD
TTIVQEAWARGQDVAIHGWIYSVENGLLSDLDVTVNKDTEKENS

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=200, Percent_Identity=59.5, Blast_Score=257, Evalue=4e-70,
Organism=Escherichia coli, GI1786534, Length=174, Percent_Identity=32.183908045977, Blast_Score=92, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=207, Percent_Identity=32.3671497584541, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23409; Mature: 23409

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKPLFENNRRWAGRILEEDPQFFEQLAKQQSPEYLWIGCSDSRVPSNQIIDLMPGEV
CCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCE
FVHRNIANMVIHTDLNCLSVLQYAVEVLKVKHIMVVGHYGCGGIKASMGKERLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHCCHHHHHHHHHHH
GHIRDIYRLHRADLDNMDESERFDRLCELNVMEQVANVTDTTIVQEAWARGQDVAIHGWI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEE
YSVENGLLSDLDVTVNKDTEKENS
EECCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MKLLKPLFENNRRWAGRILEEDPQFFEQLAKQQSPEYLWIGCSDSRVPSNQIIDLMPGEV
CCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCE
FVHRNIANMVIHTDLNCLSVLQYAVEVLKVKHIMVVGHYGCGGIKASMGKERLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHCCHHHHHHHHHHH
GHIRDIYRLHRADLDNMDESERFDRLCELNVMEQVANVTDTTIVQEAWARGQDVAIHGWI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEE
YSVENGLLSDLDVTVNKDTEKENS
EECCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]