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The map label for this gene is pabC [H]

Identifier: 157961744

GI number: 157961744

Start: 2332117

End: 2333019

Strand: Direct

Name: pabC [H]

Synonym: Spea_1921

Alternate gene names: 157961744

Gene position: 2332117-2333019 (Clockwise)

Preceding gene: 157961743

Following gene: 157961745

Centisome position: 45.07

GC content: 44.96

Gene sequence:

>903_bases
ATGACACAGGTTTGGGTAGATGGACAGCCCGATAGTCATGTTAATCCCCTTGACCGGGGGTTAGCTTATGGTGACGGTTT
ATTCGCAACCATGCGAGTACATCAGGGAAAAATACAATTCTTAGCATCACATCTTGAGCGACTGACACAAGGCGCATATC
GACTTGGGTTTTGCTGGCATCCATCTGACAAACTTCAGCTGCAACTACGCACATTAGCCGAAGATAACCCTAATTCTTGC
ATCAAAATATTACTGACGCGTGGAGTAGGCGGGCGAGGCTACGCTGCTACTGTTGTTAGACATAACCCTGCAGTAATCCT
TGAAGCTGGCAATGTACAGCAAAGCCAAGCAATAACAGCGCCGAGCTCGCAAGTCGCTGCAGCATTAAATACCACAGAGA
TTGTGTCGCTGCATAGTTTACCGATCCATTATCAAAATTGGCAGCAGCAGGGGGTAAGCCTAGCCCTTTCTGAAGTCAGA
TTAGGTAGGCAAGCTAAGCTTGCTGGTATCAAGCATTGTAATCGCTTAGAGCAGGTAATCATTAAGTCTGTAGACTTGCC
TGAGGATATCCAAGACTGGCTGGTCTTGGACTCTGATGACAATATCGTTGGATCCTCGATGGCTAATATTTTCTTTGTCT
TAGACAAAACAATTATTACACCTCGGCAGAGTTTCGCCGGGGTAGCAGGTATGATGCGCGAACAAGTTATCAATCAATTA
TTACAGATGGAGTATCAAGTCGAGGTCACCGACTTCCATCACAGTATGTTAAGTACCGCAAAGCATGTATTTATGACCAA
TAGCCTATTTGGGCTTGTCGATGTGTTGGCTATCGCAGATATGCGTTTTAGCCGTGCATCTTTGACTTTAAAGATAAGAG
AACAACTCAGTCTGACATTATGA

Upstream 100 bases:

>100_bases
TTCGTGTCTTTAAAGATCATACCGCCCCTTATATTGATTTAATCGGCATTAGTACGGCAGGACTCGAAACTGTCGTTAGC
CGTATTAGCCAGGATAGCTA

Downstream 100 bases:

>100_bases
AAAAAGCAATAATAGGTCTTCTCGCAACATTTTTTACGCTATTAACTTTGGGCGCTATAGGCGCATATTGGGGATATAAC
ACGCTGCAAGCCTATGGTGA

Product: aminodeoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTQVWVDGQPDSHVNPLDRGLAYGDGLFATMRVHQGKIQFLASHLERLTQGAYRLGFCWHPSDKLQLQLRTLAEDNPNSC
IKILLTRGVGGRGYAATVVRHNPAVILEAGNVQQSQAITAPSSQVAAALNTTEIVSLHSLPIHYQNWQQQGVSLALSEVR
LGRQAKLAGIKHCNRLEQVIIKSVDLPEDIQDWLVLDSDDNIVGSSMANIFFVLDKTIITPRQSFAGVAGMMREQVINQL
LQMEYQVEVTDFHHSMLSTAKHVFMTNSLFGLVDVLAIADMRFSRASLTLKIREQLSLTL

Sequences:

>Translated_300_residues
MTQVWVDGQPDSHVNPLDRGLAYGDGLFATMRVHQGKIQFLASHLERLTQGAYRLGFCWHPSDKLQLQLRTLAEDNPNSC
IKILLTRGVGGRGYAATVVRHNPAVILEAGNVQQSQAITAPSSQVAAALNTTEIVSLHSLPIHYQNWQQQGVSLALSEVR
LGRQAKLAGIKHCNRLEQVIIKSVDLPEDIQDWLVLDSDDNIVGSSMANIFFVLDKTIITPRQSFAGVAGMMREQVINQL
LQMEYQVEVTDFHHSMLSTAKHVFMTNSLFGLVDVLAIADMRFSRASLTLKIREQLSLTL
>Mature_299_residues
TQVWVDGQPDSHVNPLDRGLAYGDGLFATMRVHQGKIQFLASHLERLTQGAYRLGFCWHPSDKLQLQLRTLAEDNPNSCI
KILLTRGVGGRGYAATVVRHNPAVILEAGNVQQSQAITAPSSQVAAALNTTEIVSLHSLPIHYQNWQQQGVSLALSEVRL
GRQAKLAGIKHCNRLEQVIIKSVDLPEDIQDWLVLDSDDNIVGSSMANIFFVLDKTIITPRQSFAGVAGMMREQVINQLL
QMEYQVEVTDFHHSMLSTAKHVFMTNSLFGLVDVLAIADMRFSRASLTLKIREQLSLTL

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=284, Percent_Identity=34.8591549295775, Blast_Score=156, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 33308; Mature: 33177

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVWVDGQPDSHVNPLDRGLAYGDGLFATMRVHQGKIQFLASHLERLTQGAYRLGFCWH
CCEEEECCCCCCCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEC
PSDKLQLQLRTLAEDNPNSCIKILLTRGVGGRGYAATVVRHNPAVILEAGNVQQSQAITA
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCEECC
PSSQVAAALNTTEIVSLHSLPIHYQNWQQQGVSLALSEVRLGRQAKLAGIKHCNRLEQVI
CCHHHHHHCCHHHEEEEECCCCEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IKSVDLPEDIQDWLVLDSDDNIVGSSMANIFFVLDKTIITPRQSFAGVAGMMREQVINQL
HHHCCCCCCHHHCEEECCCCCCCHHHHHHEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHH
LQMEYQVEVTDFHHSMLSTAKHVFMTNSLFGLVDVLAIADMRFSRASLTLKIREQLSLTL
HHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHCCCC
>Mature Secondary Structure 
TQVWVDGQPDSHVNPLDRGLAYGDGLFATMRVHQGKIQFLASHLERLTQGAYRLGFCWH
CEEEECCCCCCCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEC
PSDKLQLQLRTLAEDNPNSCIKILLTRGVGGRGYAATVVRHNPAVILEAGNVQQSQAITA
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCEECC
PSSQVAAALNTTEIVSLHSLPIHYQNWQQQGVSLALSEVRLGRQAKLAGIKHCNRLEQVI
CCHHHHHHCCHHHEEEEECCCCEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IKSVDLPEDIQDWLVLDSDDNIVGSSMANIFFVLDKTIITPRQSFAGVAGMMREQVINQL
HHHCCCCCCHHHCEEECCCCCCCHHHHHHEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHH
LQMEYQVEVTDFHHSMLSTAKHVFMTNSLFGLVDVLAIADMRFSRASLTLKIREQLSLTL
HHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]