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The map label for this gene is fur [H]

Identifier: 157961620

GI number: 157961620

Start: 2193048

End: 2193479

Strand: Reverse

Name: fur [H]

Synonym: Spea_1796

Alternate gene names: 157961620

Gene position: 2193479-2193048 (Counterclockwise)

Preceding gene: 157961623

Following gene: 157961618

Centisome position: 42.39

GC content: 42.13

Gene sequence:

>432_bases
ATGACAGATGGAAATCAAGCACTAAAGAAAGCGGGTTTGAAAGTGACCTTACCACGAGTCAAAATTTTAGAATTGATGCA
AGCGCCGGAAAATCAACACATCAGTGCTGAGGATCTCTATAAGAAATTACTCGACTTGGGGGAAGAGATAGGTCTTGCTA
CTGTATATCGTGTTCTTAACCAATTCGATGATGCGGGCATTGTGACTCGTCATCACTTCGAAAGCGGAAAAGCCGTTTTC
GAACTTGCATCACAGCATCACCACGATCACTTAGTTTGTTTGTCATGTGGCAAAGTCATCGAATTCTCAGATGAAATGAT
TGAACGCCGTCAAGATGAAATCGCGATGAAGCACAACATTAAACTGACAAACCACAGTTTATACCTTTATGGTGTTTGCA
CTAACGATGAGTGTGACCACGGCGTAGCTTAA

Upstream 100 bases:

>100_bases
AAAGGTTTAAGTTTTCAACTGGTACACATATAATGGATTGAATACCCACAAATGAACGGATTAACTTATAGCTAATCGTT
CTGCAATCAAGAGACCAATA

Downstream 100 bases:

>100_bases
CTGCAGCGTCCGCCATAAAAGACCAGCTAAGGCTGGTTTTTTTGTATCTATTTATTAGCCTTTATCTGGCTAAAGCACTT
TATGGAATACATTCACTTTA

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MTDGNQALKKAGLKVTLPRVKILELMQAPENQHISAEDLYKKLLDLGEEIGLATVYRVLNQFDDAGIVTRHHFESGKAVF
ELASQHHHDHLVCLSCGKVIEFSDEMIERRQDEIAMKHNIKLTNHSLYLYGVCTNDECDHGVA

Sequences:

>Translated_143_residues
MTDGNQALKKAGLKVTLPRVKILELMQAPENQHISAEDLYKKLLDLGEEIGLATVYRVLNQFDDAGIVTRHHFESGKAVF
ELASQHHHDHLVCLSCGKVIEFSDEMIERRQDEIAMKHNIKLTNHSLYLYGVCTNDECDHGVA
>Mature_142_residues
TDGNQALKKAGLKVTLPRVKILELMQAPENQHISAEDLYKKLLDLGEEIGLATVYRVLNQFDDAGIVTRHHFESGKAVFE
LASQHHHDHLVCLSCGKVIEFSDEMIERRQDEIAMKHNIKLTNHSLYLYGVCTNDECDHGVA

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=138, Percent_Identity=77.536231884058, Blast_Score=229, Evalue=5e-62,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16153; Mature: 16021

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGNQALKKAGLKVTLPRVKILELMQAPENQHISAEDLYKKLLDLGEEIGLATVYRVLN
CCCHHHHHHHCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHHFESGKAVFELASQHHHDHLVCLSCGKVIEFSDEMIERRQDEIAMKHNI
HCCCCCCEEEHHCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCE
KLTNHSLYLYGVCTNDECDHGVA
EEECCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TDGNQALKKAGLKVTLPRVKILELMQAPENQHISAEDLYKKLLDLGEEIGLATVYRVLN
CCHHHHHHHCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHHFESGKAVFELASQHHHDHLVCLSCGKVIEFSDEMIERRQDEIAMKHNI
HCCCCCCEEEHHCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCE
KLTNHSLYLYGVCTNDECDHGVA
EEECCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1372314 [H]