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The map label for this gene is adrA [H]

Identifier: 157961585

GI number: 157961585

Start: 2140310

End: 2142472

Strand: Reverse

Name: adrA [H]

Synonym: Spea_1761

Alternate gene names: 157961585

Gene position: 2142472-2140310 (Counterclockwise)

Preceding gene: 157961587

Following gene: 157961583

Centisome position: 41.4

GC content: 42.49

Gene sequence:

>2163_bases
TTGGAGAGAATAGAAAAGAATAAACTCCTGTTAGCCTCAGTGTTAGGCTTAATTGGTTTACTGGTAAACCTTTATCCTAT
ACACCTATTTGCTAACATACAGCTGATCCTCGGCAACGTTTCCTACGTTATTGCCGCTGTATTGCTTGGCCCTTGGTATG
CACTCTATACTGCTATGATTACCGTTACGGGCCTAATGGTCGCCTGGGACAGCCCGCATGTTTACTTCTTATTCGGCGTA
GAAGCCCTCTTCTTAGGTTTAGCCAGAAAAAAAGATATTTACGCGTTATACGCAAGCTTTGGTTTTTGGCTGTTTATCGG
TATGCCACTTTTTTATCTTTATATCTTTCTATTTACCGATCTCCCCAGCAGTCACATCGCCTTTATCATCCTAAAGCAAG
GGATTAATGGTTTGGTCTATGCCTGCATAGGCTCGCTGATGATTACCTTAACGCCCTCTTTTTGGCACTTCAAAAGTAAG
ATAAAAGACCGACAGAGACGTACTTTCAATGGCCAGCTGACTTACACTTTTACATTAGTGATAACCGTCGCCCTGCTTTT
GGCAGCATTATTGTTCAATAATCAATTTATCGAACGCCAACAGGCCTTGCTCTATCACAATATAGAAAGCTCAGCAGCGC
ATTTAGGGCTCTCGACTCAAGCCTATATTGACTCACACACCCAAGCGATTAAGAACGCTGCAGCATGGCTCAGCTTAAAT
CAGCACTCTGAGACAGAAGAGCAAATTTTATTGTCTCATTTACATGAAAATTATCCTGGGTTTATCACCATGCTCCTTGC
CGATAGCCAAGGTGTTGTCATAGGCGCAAGTCCAGCGTCGTTACTTTCAAGCCTCGAGTCACAAAGGAAAGAACTCTCAA
TCCGTGATAGGGATTACTTTGTACAAGCCTTTATTAACCAGCGTAACTTTATCTCTCCAGCATTTCTTGGCAAAGGCTTT
GGCCAAGATCCGATTGTCGCAATAAGTGCTCCCATTTACCGAGCAGATACGCCCCACCAGCCAATAGGGATCATTGAAGG
CTCGTTAGATTTAAAAGAGTTCAAGGTGATAGATAACATCAAAACCAATCAGAATAATCAGTCCATTGTGCTTATAGATA
AAAATGGCAGAGTCATATACGCCACTGACAACCTTGGTATTACTCCACTATCTGAGTTTAATTACTCGCTACCCAGTAAA
AATTATATAACGCCCTTTCCAATGCTCAATATTTCCCATAGCGATACGATGGCGCCAGAGTACGTCTATGCAAGCGTGAC
ATTAGAAAATGATTGGCAACTATTTGTACTCAATCCTTTTCGGCCTCTAGTTGATTTGGTTGAAAGTATGTACCTAGCAA
CATTTGCCATTCTATTTGTCGCATTGTCTGTCACCATCTATATCTCACGTGTTATTAGCCGCCGCCTCACACTGCCGCTT
GAGAATATCGCCAACAAATTCAGCACTCAATCAGATAATAACTATGTGAATTATGCCGTAGATGAAGAGTCACCGGAGGA
AATTTACACCCTCTTTCAGCGCCTAAAGCAAAGTAAAAGCCAGCTTATTGGTTATCAGTTGGAGCTTGAAGAGAAAGTCG
CCGTGCGGACCTTGGAGCTTGAGCACGCTAACAGTCAATTAAAAGCTCTGGCAGAAAAAGACCCTCTTACAGGGTTATAT
AATCGCCGTTATGCCGAAGATAAGTTTCCTGGAATTCAGCAGCTATGTAAAAGAAGCGATGAGATTATTGCAATTGCGCT
GCTGGATCTTGATAAGTTCAAGTTCATTAATGATACCTACGGTCATGATGGCGGCGATCTCACTCTTAAGCGAGTCGCCG
AGCTTCTAAGCCAAGAGTTTAAGCGCGATTCAGACATCATAGTACGATATGGCGGCGAAGAGTTTTTACTCATCATGCCG
CTGTGTAATGCCTTAAAAATTGAGAATCATTTGGAAAGCTTTAGAAAAAAACTCGATAATATTGTCATCGAAAGTCAGCA
GGATAAGCAGCAATTTAAGGTGACGACCAGCATAGGGGCTGTGATTGGCAACGGGACTTATAGCGACTCACTGGAACAGT
GGGTTAAACAAGCCGATATTAATCTATATCAAGCCAAAAAGGCTGGGCGAAATAAACTGGTGTTCACGACCTTAGAAGGT
TAA

Upstream 100 bases:

>100_bases
TCATTAAAAGTTGATCTATCTCAATAAAGTTAATAAATTGTAACTAATCTCTGCCGAGATAAAAAAATAATAACGTCCAC
CGCAACAAAGGCGTGCTCAT

Downstream 100 bases:

>100_bases
TCGACAAAGTAAAAACTAAAGCTCTAAATGGGTCTGCCAAGCAAAATGTAGCGAAGCCACTACGAAAGCGCACATTTTAA
TCTTTAACCGTTAATCAGGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MERIEKNKLLLASVLGLIGLLVNLYPIHLFANIQLILGNVSYVIAAVLLGPWYALYTAMITVTGLMVAWDSPHVYFLFGV
EALFLGLARKKDIYALYASFGFWLFIGMPLFYLYIFLFTDLPSSHIAFIILKQGINGLVYACIGSLMITLTPSFWHFKSK
IKDRQRRTFNGQLTYTFTLVITVALLLAALLFNNQFIERQQALLYHNIESSAAHLGLSTQAYIDSHTQAIKNAAAWLSLN
QHSETEEQILLSHLHENYPGFITMLLADSQGVVIGASPASLLSSLESQRKELSIRDRDYFVQAFINQRNFISPAFLGKGF
GQDPIVAISAPIYRADTPHQPIGIIEGSLDLKEFKVIDNIKTNQNNQSIVLIDKNGRVIYATDNLGITPLSEFNYSLPSK
NYITPFPMLNISHSDTMAPEYVYASVTLENDWQLFVLNPFRPLVDLVESMYLATFAILFVALSVTIYISRVISRRLTLPL
ENIANKFSTQSDNNYVNYAVDEESPEEIYTLFQRLKQSKSQLIGYQLELEEKVAVRTLELEHANSQLKALAEKDPLTGLY
NRRYAEDKFPGIQQLCKRSDEIIAIALLDLDKFKFINDTYGHDGGDLTLKRVAELLSQEFKRDSDIIVRYGGEEFLLIMP
LCNALKIENHLESFRKKLDNIVIESQQDKQQFKVTTSIGAVIGNGTYSDSLEQWVKQADINLYQAKKAGRNKLVFTTLEG

Sequences:

>Translated_720_residues
MERIEKNKLLLASVLGLIGLLVNLYPIHLFANIQLILGNVSYVIAAVLLGPWYALYTAMITVTGLMVAWDSPHVYFLFGV
EALFLGLARKKDIYALYASFGFWLFIGMPLFYLYIFLFTDLPSSHIAFIILKQGINGLVYACIGSLMITLTPSFWHFKSK
IKDRQRRTFNGQLTYTFTLVITVALLLAALLFNNQFIERQQALLYHNIESSAAHLGLSTQAYIDSHTQAIKNAAAWLSLN
QHSETEEQILLSHLHENYPGFITMLLADSQGVVIGASPASLLSSLESQRKELSIRDRDYFVQAFINQRNFISPAFLGKGF
GQDPIVAISAPIYRADTPHQPIGIIEGSLDLKEFKVIDNIKTNQNNQSIVLIDKNGRVIYATDNLGITPLSEFNYSLPSK
NYITPFPMLNISHSDTMAPEYVYASVTLENDWQLFVLNPFRPLVDLVESMYLATFAILFVALSVTIYISRVISRRLTLPL
ENIANKFSTQSDNNYVNYAVDEESPEEIYTLFQRLKQSKSQLIGYQLELEEKVAVRTLELEHANSQLKALAEKDPLTGLY
NRRYAEDKFPGIQQLCKRSDEIIAIALLDLDKFKFINDTYGHDGGDLTLKRVAELLSQEFKRDSDIIVRYGGEEFLLIMP
LCNALKIENHLESFRKKLDNIVIESQQDKQQFKVTTSIGAVIGNGTYSDSLEQWVKQADINLYQAKKAGRNKLVFTTLEG
>Mature_720_residues
MERIEKNKLLLASVLGLIGLLVNLYPIHLFANIQLILGNVSYVIAAVLLGPWYALYTAMITVTGLMVAWDSPHVYFLFGV
EALFLGLARKKDIYALYASFGFWLFIGMPLFYLYIFLFTDLPSSHIAFIILKQGINGLVYACIGSLMITLTPSFWHFKSK
IKDRQRRTFNGQLTYTFTLVITVALLLAALLFNNQFIERQQALLYHNIESSAAHLGLSTQAYIDSHTQAIKNAAAWLSLN
QHSETEEQILLSHLHENYPGFITMLLADSQGVVIGASPASLLSSLESQRKELSIRDRDYFVQAFINQRNFISPAFLGKGF
GQDPIVAISAPIYRADTPHQPIGIIEGSLDLKEFKVIDNIKTNQNNQSIVLIDKNGRVIYATDNLGITPLSEFNYSLPSK
NYITPFPMLNISHSDTMAPEYVYASVTLENDWQLFVLNPFRPLVDLVESMYLATFAILFVALSVTIYISRVISRRLTLPL
ENIANKFSTQSDNNYVNYAVDEESPEEIYTLFQRLKQSKSQLIGYQLELEEKVAVRTLELEHANSQLKALAEKDPLTGLY
NRRYAEDKFPGIQQLCKRSDEIIAIALLDLDKFKFINDTYGHDGGDLTLKRVAELLSQEFKRDSDIIVRYGGEEFLLIMP
LCNALKIENHLESFRKKLDNIVIESQQDKQQFKVTTSIGAVIGNGTYSDSLEQWVKQADINLYQAKKAGRNKLVFTTLEG

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1787262, Length=207, Percent_Identity=29.951690821256, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=34.3023255813954, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081881, Length=238, Percent_Identity=33.1932773109244, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=31.875, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787802, Length=177, Percent_Identity=33.8983050847458, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=32.0987654320988, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788381, Length=173, Percent_Identity=31.2138728323699, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788956, Length=261, Percent_Identity=30.6513409961686, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081977, Length=172, Percent_Identity=33.7209302325581, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=31.3253012048193, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=32.6923076923077, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1787541, Length=182, Percent_Identity=28.021978021978, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 81458; Mature: 81458

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIEKNKLLLASVLGLIGLLVNLYPIHLFANIQLILGNVSYVIAAVLLGPWYALYTAMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHEECCHHHHHHHHHHHHHHHHHHHHH
TVTGLMVAWDSPHVYFLFGVEALFLGLARKKDIYALYASFGFWLFIGMPLFYLYIFLFTD
HHHHHEEEECCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPSSHIAFIILKQGINGLVYACIGSLMITLTPSFWHFKSKIKDRQRRTFNGQLTYTFTLV
CCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHH
ITVALLLAALLFNNQFIERQQALLYHNIESSAAHLGLSTQAYIDSHTQAIKNAAAWLSLN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEC
QHSETEEQILLSHLHENYPGFITMLLADSQGVVIGASPASLLSSLESQRKELSIRDRDYF
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHH
VQAFINQRNFISPAFLGKGFGQDPIVAISAPIYRADTPHQPIGIIEGSLDLKEFKVIDNI
HHHHHCCCCCCCHHHHCCCCCCCCEEEEECCEEECCCCCCCCEEEECCCCHHHHHHHHCC
KTNQNNQSIVLIDKNGRVIYATDNLGITPLSEFNYSLPSKNYITPFPMLNISHSDTMAPE
CCCCCCCEEEEEECCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCC
YVYASVTLENDWQLFVLNPFRPLVDLVESMYLATFAILFVALSVTIYISRVISRRLTLPL
EEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ENIANKFSTQSDNNYVNYAVDEESPEEIYTLFQRLKQSKSQLIGYQLELEEKVAVRTLEL
HHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHEEEEH
EHANSQLKALAEKDPLTGLYNRRYAEDKFPGIQQLCKRSDEIIAIALLDLDKFKFINDTY
HHCCHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHCCCCCEEEEEEECCHHHHHCCCCC
GHDGGDLTLKRVAELLSQEFKRDSDIIVRYGGEEFLLIMPLCNALKIENHLESFRKKLDN
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHH
IVIESQQDKQQFKVTTSIGAVIGNGTYSDSLEQWVKQADINLYQAKKAGRNKLVFTTLEG
HEECCCCCHHHEEEEEHHHHEECCCCCHHHHHHHHHHHCCCCEEHHHCCCCEEEEEEECC
>Mature Secondary Structure
MERIEKNKLLLASVLGLIGLLVNLYPIHLFANIQLILGNVSYVIAAVLLGPWYALYTAMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHEECCHHHHHHHHHHHHHHHHHHHHH
TVTGLMVAWDSPHVYFLFGVEALFLGLARKKDIYALYASFGFWLFIGMPLFYLYIFLFTD
HHHHHEEEECCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPSSHIAFIILKQGINGLVYACIGSLMITLTPSFWHFKSKIKDRQRRTFNGQLTYTFTLV
CCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHH
ITVALLLAALLFNNQFIERQQALLYHNIESSAAHLGLSTQAYIDSHTQAIKNAAAWLSLN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEC
QHSETEEQILLSHLHENYPGFITMLLADSQGVVIGASPASLLSSLESQRKELSIRDRDYF
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHH
VQAFINQRNFISPAFLGKGFGQDPIVAISAPIYRADTPHQPIGIIEGSLDLKEFKVIDNI
HHHHHCCCCCCCHHHHCCCCCCCCEEEEECCEEECCCCCCCCEEEECCCCHHHHHHHHCC
KTNQNNQSIVLIDKNGRVIYATDNLGITPLSEFNYSLPSKNYITPFPMLNISHSDTMAPE
CCCCCCCEEEEEECCCEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCCC
YVYASVTLENDWQLFVLNPFRPLVDLVESMYLATFAILFVALSVTIYISRVISRRLTLPL
EEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ENIANKFSTQSDNNYVNYAVDEESPEEIYTLFQRLKQSKSQLIGYQLELEEKVAVRTLEL
HHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHEEEEH
EHANSQLKALAEKDPLTGLYNRRYAEDKFPGIQQLCKRSDEIIAIALLDLDKFKFINDTY
HHCCHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHCCCCCEEEEEEECCHHHHHCCCCC
GHDGGDLTLKRVAELLSQEFKRDSDIIVRYGGEEFLLIMPLCNALKIENHLESFRKKLDN
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHH
IVIESQQDKQQFKVTTSIGAVIGNGTYSDSLEQWVKQADINLYQAKKAGRNKLVFTTLEG
HEECCCCCHHHEEEEEHHHHEECCCCCHHHHHHHHHHHCCCCEEHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]