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The map label for this gene is chuR [H]

Identifier: 157961556

GI number: 157961556

Start: 2107242

End: 2108423

Strand: Reverse

Name: chuR [H]

Synonym: Spea_1732

Alternate gene names: 157961556

Gene position: 2108423-2107242 (Counterclockwise)

Preceding gene: 157961557

Following gene: 157961555

Centisome position: 40.75

GC content: 43.15

Gene sequence:

>1182_bases
ATGTCATCACAAGCTACATACCCATTTCACCTTCTGGTTAAACCGGTTGGTGCTAAGTGTAATCTCGATTGCCATTACTG
CTATTACCTACGTAAAGAGGAACGATACGAGCCTAATGCGACGATGCAGATGTCTGAAGAGTTGCTGGAAAGCTATATTT
CTCAGTACATTGCAACTCAGCCGTCTCATATAAACAGTGTTGATTTTAGCTGGCAAGGTGGTGAACCGGCACTGCGTGGG
CTCGCTTTTTTTGAACGAGCAGTCGAGTTACAAAAACAGTATGCTCGCCCTGGTATGCAGATCTCCAATACCTTTCAAAG
TAACGGTACGCTAATCAACGAACGCTGGGCGAAGTTCTTCAAGAAAAATAACTTTTTAATCGGTTTGAGCATAGATGGCG
ATGAGCTTAATCATGGCAACGGTCGACCAGACTTAAAAGGCAACAATAGCTACCCCAAGGTAATGCGAGGACTCGCACTA
CTAAAGGAACATAATGTCAATTTTAATACCCTAACCGTTGTACATTGTGATAATGCCCACCTAGGTAAACAAACCTACAA
TAAATTAAAAGAATTAGGCTCCACAGTCATTCAATTTCAGCCCTGCGTTGAACATGACCGCGATAGAAGAGCTAGCAAAG
ATTGGTCTTTATCCCCACAACAATGGGGCAAGTTTTTATGTGATGTCTTCGACGAGTGGAAAAAAGAGGATGTTGGTAAG
GTCTTTATACAATTGTTTGAAAATACACTCGCTATTTTAGCAGGGCAGCCGAGTCAAATGTGCTTTCATTCTGAAGCGTG
CGGGCAGCAACTCATGCTTGAACATGATGGAAGTGTCTACTCATGCGACCACTATAGTTATGATGACTATAAACTGGGCA
ATATCGATATCGTCGATCTTGGCAAAATGGCCAGTGGTGAAAACCAGTCACAGTTTGGTTTAGCTAAATGGCACTCACTA
ACGAAACAGTGCCGAGAGTGTGACTTTAGACCTTTTTGCAACGGCGGATGTCCAAAAGAGCGAACGGCAATCACAGCAGA
CTTGGAGCCAGGTTTACATCACCTATGTCGCGGCTATAAACAATTCTTCATGCATTCTATGCCCTACCTTGGCGCAATGT
TAGAAACCATTAATAATGGCTACCCTGCAAACCTATACCCTATGTATCTTCAAAGAAGCTAG

Upstream 100 bases:

>100_bases
TCATAGCCGAAATCTAATTTAGCCTCAGACATTAGGAGACTTCCTAGTCGATCCCTTGCTAGCTTGAAGAGATAATGGGA
CCCAATAGAGGAGTTTCTAT

Downstream 100 bases:

>100_bases
CAGCATCGACAACTGATAACGAAGGTCATTAACGACCTTCGTGGTTTCGTAATCCAAGCTCAGCTCTATTATTCCGCGTC
TCCCCACGGCTCTGACTGCA

Product: radical SAM domain-containing protein

Products: NA

Alternate protein names: AnSME; Chondroitin sulfate/heparin utilization regulation protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSSQATYPFHLLVKPVGAKCNLDCHYCYYLRKEERYEPNATMQMSEELLESYISQYIATQPSHINSVDFSWQGGEPALRG
LAFFERAVELQKQYARPGMQISNTFQSNGTLINERWAKFFKKNNFLIGLSIDGDELNHGNGRPDLKGNNSYPKVMRGLAL
LKEHNVNFNTLTVVHCDNAHLGKQTYNKLKELGSTVIQFQPCVEHDRDRRASKDWSLSPQQWGKFLCDVFDEWKKEDVGK
VFIQLFENTLAILAGQPSQMCFHSEACGQQLMLEHDGSVYSCDHYSYDDYKLGNIDIVDLGKMASGENQSQFGLAKWHSL
TKQCRECDFRPFCNGGCPKERTAITADLEPGLHHLCRGYKQFFMHSMPYLGAMLETINNGYPANLYPMYLQRS

Sequences:

>Translated_393_residues
MSSQATYPFHLLVKPVGAKCNLDCHYCYYLRKEERYEPNATMQMSEELLESYISQYIATQPSHINSVDFSWQGGEPALRG
LAFFERAVELQKQYARPGMQISNTFQSNGTLINERWAKFFKKNNFLIGLSIDGDELNHGNGRPDLKGNNSYPKVMRGLAL
LKEHNVNFNTLTVVHCDNAHLGKQTYNKLKELGSTVIQFQPCVEHDRDRRASKDWSLSPQQWGKFLCDVFDEWKKEDVGK
VFIQLFENTLAILAGQPSQMCFHSEACGQQLMLEHDGSVYSCDHYSYDDYKLGNIDIVDLGKMASGENQSQFGLAKWHSL
TKQCRECDFRPFCNGGCPKERTAITADLEPGLHHLCRGYKQFFMHSMPYLGAMLETINNGYPANLYPMYLQRS
>Mature_392_residues
SSQATYPFHLLVKPVGAKCNLDCHYCYYLRKEERYEPNATMQMSEELLESYISQYIATQPSHINSVDFSWQGGEPALRGL
AFFERAVELQKQYARPGMQISNTFQSNGTLINERWAKFFKKNNFLIGLSIDGDELNHGNGRPDLKGNNSYPKVMRGLALL
KEHNVNFNTLTVVHCDNAHLGKQTYNKLKELGSTVIQFQPCVEHDRDRRASKDWSLSPQQWGKFLCDVFDEWKKEDVGKV
FIQLFENTLAILAGQPSQMCFHSEACGQQLMLEHDGSVYSCDHYSYDDYKLGNIDIVDLGKMASGENQSQFGLAKWHSLT
KQCRECDFRPFCNGGCPKERTAITADLEPGLHHLCRGYKQFFMHSMPYLGAMLETINNGYPANLYPMYLQRS

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Links the heparin and the chondroitin sulfate utilization pathways which contribute to the colonization of the intestinal tract. May catalyze the activation of chondro-6- sulfatase, i

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=395, Percent_Identity=40.5063291139241, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI87081923, Length=383, Percent_Identity=37.0757180156658, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 45006; Mature: 44875

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQATYPFHLLVKPVGAKCNLDCHYCYYLRKEERYEPNATMQMSEELLESYISQYIATQ
CCCCCCCCEEEEEECCCCCCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PSHINSVDFSWQGGEPALRGLAFFERAVELQKQYARPGMQISNTFQSNGTLINERWAKFF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHH
KKNNFLIGLSIDGDELNHGNGRPDLKGNNSYPKVMRGLALLKEHNVNFNTLTVVHCDNAH
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
LGKQTYNKLKELGSTVIQFQPCVEHDRDRRASKDWSLSPQQWGKFLCDVFDEWKKEDVGK
CCHHHHHHHHHHHHHHEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VFIQLFENTLAILAGQPSQMCFHSEACGQQLMLEHDGSVYSCDHYSYDDYKLGNIDIVDL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCEEECCCCCCCCEEECCEEEEEC
GKMASGENQSQFGLAKWHSLTKQCRECDFRPFCNGGCPKERTAITADLEPGLHHLCRGYK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
QFFMHSMPYLGAMLETINNGYPANLYPMYLQRS
HHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SSQATYPFHLLVKPVGAKCNLDCHYCYYLRKEERYEPNATMQMSEELLESYISQYIATQ
CCCCCCCEEEEEECCCCCCCCCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PSHINSVDFSWQGGEPALRGLAFFERAVELQKQYARPGMQISNTFQSNGTLINERWAKFF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHH
KKNNFLIGLSIDGDELNHGNGRPDLKGNNSYPKVMRGLALLKEHNVNFNTLTVVHCDNAH
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCC
LGKQTYNKLKELGSTVIQFQPCVEHDRDRRASKDWSLSPQQWGKFLCDVFDEWKKEDVGK
CCHHHHHHHHHHHHHHEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VFIQLFENTLAILAGQPSQMCFHSEACGQQLMLEHDGSVYSCDHYSYDDYKLGNIDIVDL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCEEECCCCCCCCEEECCEEEEEC
GKMASGENQSQFGLAKWHSLTKQCRECDFRPFCNGGCPKERTAITADLEPGLHHLCRGYK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
QFFMHSMPYLGAMLETINNGYPANLYPMYLQRS
HHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1429442; 12663928 [H]