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The map label for this gene is fabH2 [H]

Identifier: 157961525

GI number: 157961525

Start: 2066038

End: 2067102

Strand: Reverse

Name: fabH2 [H]

Synonym: Spea_1700

Alternate gene names: 157961525

Gene position: 2067102-2066038 (Counterclockwise)

Preceding gene: 157961526

Following gene: 157961511

Centisome position: 39.95

GC content: 47.23

Gene sequence:

>1065_bases
ATGCAGTACGCCACTATTACTGGTTGGGGAAAGTGTGTTCCGCCTGCCACCCTAACAAACCATGATCTTGCCACTTTTAT
TGAAACCTCAGACGAGTGGATCAAACCGCGCACAGGCATTAGCCAAAGACACATTAGCCACGTTGATACGTCGGCTTTGG
CCTCTGTTGCCGCCAAACGAGCACTCGCAGCAGCGGGGATCGATGGTAGTGAACTAGATATGATTATTCTTGCCACGGCG
ACCCCAGATACCCTGATCCCGAATATTGCTTCTACCGTACAGGCTGAAGTGGGTGCAACCTGTGCAGCTTTTGATATCAA
CGCCGCCTGTAGTGGCTTTTTATATGGCCTAGGCTTAGGTAGTTCACAGATCAAGAGCGGTCAGTGTAAGAAAGTACTTG
TGATCGGTGCCGAGCGTCTTTCATTTTTCTTAGACTGGTCTCGTCGCGACACTGCCGTACTTTTCGGTGATGGCGCTGGC
GCTGTCGTGCTAGAAGCAACTGACGAAGCGATTGGTGTATTGGGTTATGAGCTAAATAACGACCCAGATGGCCGTGATAT
CCTTAAAGCTGGATTTGGTACGGCTATGGATAGATTTGAAGCTTCATCTTTAGATTTCTACATAGAATTTAACGGTCAAG
AGATCTTTAAACGCGCTATCGCAGGCATGGGTAAGTTAAGCGCTAAAGTTATCGAAAAGTGCGGTATCGATAAAGAAGAG
ATCGATTGGGTTATTCCTCATCAGGCGAACGAGCGTATTATCGATACGTTAATTAGCCGCATGAAGATCCCGAAAGAGAA
AGCGGTTGTGAACATAGCCAACTACGGTAACACCTCTGCAGCGACCATTCCGATTGCAATCTGTGACGCCCTAGAGCAAG
GTAAAATTCAACCTAACCAAACTATTCTATCTTGTGCATTTGGTGCAGGTCTAACGTCTGCTGCGGCATTGATTAAATGG
GGTGACAGAGTCACACCAATTAATACTAGCGATGCAGAGCTACCTCCTTGTGATAAAACAGGTATTGAGCTCGTCGCGAA
AGCGGTTAAGCATTTCTGCGGCTAA

Upstream 100 bases:

>100_bases
CTCACAGTTTGATTAGCATGATTTTTGCTAAACTTCACTTATACAGATCCCATAAGGCAGAGCTCAGGTTCTGCCTTTTT
AATTGATAGAGAATACCTAG

Downstream 100 bases:

>100_bases
CGTTATAGTTTGCATTGCATTAATAAAAAAACACCGAGTCATATCGGTGTTTTTTTATGGGCGTTTAACGCTGACTTAAT
GTAATTTAATGCCAATCAGT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MQYATITGWGKCVPPATLTNHDLATFIETSDEWIKPRTGISQRHISHVDTSALASVAAKRALAAAGIDGSELDMIILATA
TPDTLIPNIASTVQAEVGATCAAFDINAACSGFLYGLGLGSSQIKSGQCKKVLVIGAERLSFFLDWSRRDTAVLFGDGAG
AVVLEATDEAIGVLGYELNNDPDGRDILKAGFGTAMDRFEASSLDFYIEFNGQEIFKRAIAGMGKLSAKVIEKCGIDKEE
IDWVIPHQANERIIDTLISRMKIPKEKAVVNIANYGNTSAATIPIAICDALEQGKIQPNQTILSCAFGAGLTSAAALIKW
GDRVTPINTSDAELPPCDKTGIELVAKAVKHFCG

Sequences:

>Translated_354_residues
MQYATITGWGKCVPPATLTNHDLATFIETSDEWIKPRTGISQRHISHVDTSALASVAAKRALAAAGIDGSELDMIILATA
TPDTLIPNIASTVQAEVGATCAAFDINAACSGFLYGLGLGSSQIKSGQCKKVLVIGAERLSFFLDWSRRDTAVLFGDGAG
AVVLEATDEAIGVLGYELNNDPDGRDILKAGFGTAMDRFEASSLDFYIEFNGQEIFKRAIAGMGKLSAKVIEKCGIDKEE
IDWVIPHQANERIIDTLISRMKIPKEKAVVNIANYGNTSAATIPIAICDALEQGKIQPNQTILSCAFGAGLTSAAALIKW
GDRVTPINTSDAELPPCDKTGIELVAKAVKHFCG
>Mature_354_residues
MQYATITGWGKCVPPATLTNHDLATFIETSDEWIKPRTGISQRHISHVDTSALASVAAKRALAAAGIDGSELDMIILATA
TPDTLIPNIASTVQAEVGATCAAFDINAACSGFLYGLGLGSSQIKSGQCKKVLVIGAERLSFFLDWSRRDTAVLFGDGAG
AVVLEATDEAIGVLGYELNNDPDGRDILKAGFGTAMDRFEASSLDFYIEFNGQEIFKRAIAGMGKLSAKVIEKCGIDKEE
IDWVIPHQANERIIDTLISRMKIPKEKAVVNIANYGNTSAATIPIAICDALEQGKIQPNQTILSCAFGAGLTSAAALIKW
GDRVTPINTSDAELPPCDKTGIELVAKAVKHFCG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=35.8255451713396, Blast_Score=211, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37564; Mature: 37564

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYATITGWGKCVPPATLTNHDLATFIETSDEWIKPRTGISQRHISHVDTSALASVAAKR
CCEEEECCCCCCCCCCCCCCCCHHHEEECCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHH
ALAAAGIDGSELDMIILATATPDTLIPNIASTVQAEVGATCAAFDINAACSGFLYGLGLG
HHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCC
SSQIKSGQCKKVLVIGAERLSFFLDWSRRDTAVLFGDGAGAVVLEATDEAIGVLGYELNN
HHHCCCCCCCEEEEEEHHHHEEEEECCCCCCEEEEECCCCEEEEEECCCEEEEEEEECCC
DPDGRDILKAGFGTAMDRFEASSLDFYIEFNGQEIFKRAIAGMGKLSAKVIEKCGIDKEE
CCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCHHH
IDWVIPHQANERIIDTLISRMKIPKEKAVVNIANYGNTSAATIPIAICDALEQGKIQPNQ
CCEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCH
TILSCAFGAGLTSAAALIKWGDRVTPINTSDAELPPCDKTGIELVAKAVKHFCG
HEEEEHHCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQYATITGWGKCVPPATLTNHDLATFIETSDEWIKPRTGISQRHISHVDTSALASVAAKR
CCEEEECCCCCCCCCCCCCCCCHHHEEECCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHH
ALAAAGIDGSELDMIILATATPDTLIPNIASTVQAEVGATCAAFDINAACSGFLYGLGLG
HHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCC
SSQIKSGQCKKVLVIGAERLSFFLDWSRRDTAVLFGDGAGAVVLEATDEAIGVLGYELNN
HHHCCCCCCCEEEEEEHHHHEEEEECCCCCCEEEEECCCCEEEEEECCCEEEEEEEECCC
DPDGRDILKAGFGTAMDRFEASSLDFYIEFNGQEIFKRAIAGMGKLSAKVIEKCGIDKEE
CCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHCCCHHH
IDWVIPHQANERIIDTLISRMKIPKEKAVVNIANYGNTSAATIPIAICDALEQGKIQPNQ
CCEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCH
TILSCAFGAGLTSAAALIKWGDRVTPINTSDAELPPCDKTGIELVAKAVKHFCG
HEEEEHHCCCHHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]