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The map label for this gene is mcp4 [H]

Identifier: 157961463

GI number: 157961463

Start: 1982571

End: 1984019

Strand: Direct

Name: mcp4 [H]

Synonym: Spea_1637

Alternate gene names: 157961463

Gene position: 1982571-1984019 (Clockwise)

Preceding gene: 157961462

Following gene: 157961468

Centisome position: 38.31

GC content: 47.83

Gene sequence:

>1449_bases
ATGAAACAGATTAGTTTTCGTAAAGTCGATGCTGTACTAATCAAACTTAGCTTGAACGGAAAATTTTGGGCGATTTGTAC
CATGGTGGCAATGATCACCGCAGCAATCGCCACGCTCAATTACAACAATACCCAATCGTTAATTGAATCCTCTTCTTTAA
ACCGTGCTCAGTCGAGTGTTGATGCCTATGCGGCAATCGCAAAATCTCAAGCGCTGACAGGAAGCGCTCTGGCCGAATTT
GCTCAACAAGCAGGCCTCAAAATCTCTGGCAGTTCAATTACCCAGCGACGCAATGACTTGCTGACCGTCAGTGCTCAAGT
CGACGATAAGGCGTTAACGGCTCAAGTTGACGTAACGAGCTGGGAGCAAGAGGCACTAGCTCATGCTAATAAGATGCTGC
TGTTAGCCTTTGCAGGGTTATTACCGCTGTTTTTGGTCAGTTATTGGGTGTCGACTTCACTCGGTGGCGGCTTATGGGAT
ATGTACATGGCCATCAAACGTTTGGCCGACGGTGATTTAAGTCAAAGACTTAATTTCTTTGGTAAAGATGATTTTAGCCT
TATTGCCCGTGAGATTGACCGAAGCGCCGATAATATGAGTGAGATGGTGCAGGCAATTTCACGCAATGCACAGACCCTTA
ATGAGGCGGCTGATGAGTTTACTCAGCAAGCGGGACATAGCGTAGAACTAACCGATTATCAGCATCAGTTTCTCGATACA
GTTGCCGTCGCCATGGCCCAGATGACGGCAGCGGTGGAAGAAGTTTCACACAGTGCTTCTAATACCTCAGATCAGACTCA
GCAAAATGCGGCGCAGGCTGCCAATAGTCAGACATTAATTACAGAAGCGGTTGCGCGTATTGCCGTGCTAAGCACAAAAA
TCTCAGAAGCTTCTGTATCGGTACAAGATCTGTCTCAAGCGGCGTCAGATATTGGCGCGGTTGTGACAACGATCAACAGT
ATTTCAGAGCAGACTAATCTGTTAGCACTTAACGCTGCTATCGAAGCGGCGCGGGCTGGTGAGCAGGGCAGAGGCTTTGC
CGTTGTCGCCGATGAGGTGAGAACGCTTGCGAGCCGAACCCAGCAAGCGACGGTTGAGATCCAATCTATGATTGAAGGAT
TACAAACGGGCACCGGCAAGCTTTCAAATATTACCAATGATATCGTATCGCAGGCAGATAAGGGCAGGGCGGCCATAGAG
TCAGTAGGCCAAGATGTGGATAGTATGGCTGAGTCTATCAGCATAGTATTTGATATGAGCTCGCAGATAGCGGCATCATC
AGAGGAACAAAGCGCGGCTTCACGTGAAATTGCAACTCAGTTAAATGATATTCGCGCCCAGGCTGAAACGATTAAGCAAA
CGGCTCAGAGTTCGGTGGATCTGGCGACTAATTTGACGGATTCATCCAGAGGCTTAGAGCAGATTTTAGGCCAATATAAG
ATCAGCTAA

Upstream 100 bases:

>100_bases
GTCAGGATTAAGTCAGGATTAAGTCAGGATTAAGTCAGGACTAAATTAGGGCTAAGTGAGATTTAAGCGCTATACGTAAG
GCTAAGCCAAGGAAATCATA

Downstream 100 bases:

>100_bases
GGCTTATTTGCTTTGTAGTAATCGCTATTGTTGATAAATAAGATTGATGAACAAGTCTAATTGTTAAGCTTTTGAATATG
TTAAAAAAATGCCAGCTATT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MKQISFRKVDAVLIKLSLNGKFWAICTMVAMITAAIATLNYNNTQSLIESSSLNRAQSSVDAYAAIAKSQALTGSALAEF
AQQAGLKISGSSITQRRNDLLTVSAQVDDKALTAQVDVTSWEQEALAHANKMLLLAFAGLLPLFLVSYWVSTSLGGGLWD
MYMAIKRLADGDLSQRLNFFGKDDFSLIAREIDRSADNMSEMVQAISRNAQTLNEAADEFTQQAGHSVELTDYQHQFLDT
VAVAMAQMTAAVEEVSHSASNTSDQTQQNAAQAANSQTLITEAVARIAVLSTKISEASVSVQDLSQAASDIGAVVTTINS
ISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQSMIEGLQTGTGKLSNITNDIVSQADKGRAAIE
SVGQDVDSMAESISIVFDMSSQIAASSEEQSAASREIATQLNDIRAQAETIKQTAQSSVDLATNLTDSSRGLEQILGQYK
IS

Sequences:

>Translated_482_residues
MKQISFRKVDAVLIKLSLNGKFWAICTMVAMITAAIATLNYNNTQSLIESSSLNRAQSSVDAYAAIAKSQALTGSALAEF
AQQAGLKISGSSITQRRNDLLTVSAQVDDKALTAQVDVTSWEQEALAHANKMLLLAFAGLLPLFLVSYWVSTSLGGGLWD
MYMAIKRLADGDLSQRLNFFGKDDFSLIAREIDRSADNMSEMVQAISRNAQTLNEAADEFTQQAGHSVELTDYQHQFLDT
VAVAMAQMTAAVEEVSHSASNTSDQTQQNAAQAANSQTLITEAVARIAVLSTKISEASVSVQDLSQAASDIGAVVTTINS
ISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQSMIEGLQTGTGKLSNITNDIVSQADKGRAAIE
SVGQDVDSMAESISIVFDMSSQIAASSEEQSAASREIATQLNDIRAQAETIKQTAQSSVDLATNLTDSSRGLEQILGQYK
IS
>Mature_482_residues
MKQISFRKVDAVLIKLSLNGKFWAICTMVAMITAAIATLNYNNTQSLIESSSLNRAQSSVDAYAAIAKSQALTGSALAEF
AQQAGLKISGSSITQRRNDLLTVSAQVDDKALTAQVDVTSWEQEALAHANKMLLLAFAGLLPLFLVSYWVSTSLGGGLWD
MYMAIKRLADGDLSQRLNFFGKDDFSLIAREIDRSADNMSEMVQAISRNAQTLNEAADEFTQQAGHSVELTDYQHQFLDT
VAVAMAQMTAAVEEVSHSASNTSDQTQQNAAQAANSQTLITEAVARIAVLSTKISEASVSVQDLSQAASDIGAVVTTINS
ISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQSMIEGLQTGTGKLSNITNDIVSQADKGRAAIE
SVGQDVDSMAESISIVFDMSSQIAASSEEQSAASREIATQLNDIRAQAETIKQTAQSSVDLATNLTDSSRGLEQILGQYK
IS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=293, Percent_Identity=31.3993174061433, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=28.956228956229, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787690, Length=267, Percent_Identity=32.5842696629214, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788194, Length=271, Percent_Identity=28.7822878228782, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789453, Length=270, Percent_Identity=32.5925925925926, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 51357; Mature: 51357

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQISFRKVDAVLIKLSLNGKFWAICTMVAMITAAIATLNYNNTQSLIESSSLNRAQSSV
CCCCCHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DAYAAIAKSQALTGSALAEFAQQAGLKISGSSITQRRNDLLTVSAQVDDKALTAQVDVTS
HHHHHHHHHHHCCHHHHHHHHHHCCCEECCCHHHHHCCCEEEEEEECCCCCEEEEEECCH
WEQEALAHANKMLLLAFAGLLPLFLVSYWVSTSLGGGLWDMYMAIKRLADGDLSQRLNFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHC
GKDDFSLIAREIDRSADNMSEMVQAISRNAQTLNEAADEFTQQAGHSVELTDYQHQFLDT
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
VAVAMAQMTAAVEEVSHSASNTSDQTQQNAAQAANSQTLITEAVARIAVLSTKISEASVS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
VQDLSQAASDIGAVVTTINSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QQATVEIQSMIEGLQTGTGKLSNITNDIVSQADKGRAAIESVGQDVDSMAESISIVFDMS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHEECH
SQIAASSEEQSAASREIATQLNDIRAQAETIKQTAQSSVDLATNLTDSSRGLEQILGQYK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
IS
CC
>Mature Secondary Structure
MKQISFRKVDAVLIKLSLNGKFWAICTMVAMITAAIATLNYNNTQSLIESSSLNRAQSSV
CCCCCHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DAYAAIAKSQALTGSALAEFAQQAGLKISGSSITQRRNDLLTVSAQVDDKALTAQVDVTS
HHHHHHHHHHHCCHHHHHHHHHHCCCEECCCHHHHHCCCEEEEEEECCCCCEEEEEECCH
WEQEALAHANKMLLLAFAGLLPLFLVSYWVSTSLGGGLWDMYMAIKRLADGDLSQRLNFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHC
GKDDFSLIAREIDRSADNMSEMVQAISRNAQTLNEAADEFTQQAGHSVELTDYQHQFLDT
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
VAVAMAQMTAAVEEVSHSASNTSDQTQQNAAQAANSQTLITEAVARIAVLSTKISEASVS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
VQDLSQAASDIGAVVTTINSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QQATVEIQSMIEGLQTGTGKLSNITNDIVSQADKGRAAIESVGQDVDSMAESISIVFDMS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHEECH
SQIAASSEEQSAASREIATQLNDIRAQAETIKQTAQSSVDLATNLTDSSRGLEQILGQYK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
IS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]