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The map label for this gene is mtnN [H]

Identifier: 157961390

GI number: 157961390

Start: 1900820

End: 1901632

Strand: Reverse

Name: mtnN [H]

Synonym: Spea_1564

Alternate gene names: 157961390

Gene position: 1901632-1900820 (Counterclockwise)

Preceding gene: 157961392

Following gene: 157961385

Centisome position: 36.75

GC content: 46.74

Gene sequence:

>813_bases
ATGCGCACCACTCTTGCTATTTTCGCATTACTCTACCCACTGTTCTCTATCAATGCATTTGCAAATACTAATTCTGATGT
TAAACCCGTTTCAAAAACCCCAACCGAAATAAAATCGCAAACTATCGCTATTTTAGGCGCTATGGATGCAGAAATTGAAA
AGCTACTGCCTGAGATAAAGCAGCGTCAAACCCACACCATTGCCAAGAATACTTACTACACGGGTGTTATCCAAGGTAAA
CCTGTAGTGGTTGCTCGCTCAGGCGTAGGTAAAGTTAATGCGGCTATCACCACTTATGTATTGATTAATCATTTTGACGT
AAACAGTATTATTTTCACCGGTATTGCTGGCGCAGCAGGGCCGGACCTCAATGTTGCCGATGTGGTGATTTCGACTGCAC
TTGTGCAGCACGACGTCGACTTAACCGCCTTTGGCGCGCCAAAAGGGCTGCTCGATGGTTATGACGACCGCCTCTTCTAT
GCTGATAAAAAACTACAAGCACTAGCCCTTAATGCGGCAGTGGAGTCGGTAGGTAAGGCTCGCGTACACACAGGCATTAT
CGCTACTGGCGATCAGTTTATTGCCGATAAAGCCGTGGTGAGCATGTTACTTAAAGAGTTCAGCGCTATCGCCGTCGAGA
TGGAAGGCGCCGCAGTGGCTCAGGTGACCGATATGTTTGATATTCCGCTAGTTGTCATTCGCACTATCTCTGACAAAGCC
GATGGCTCGGCGCACTTAGTCTATGAAGAAGCTAAGCAAGTCACCGCCGATAACTCGGTCGCAATCACACTAAATATGCT
TAGTCAGATGTAA

Upstream 100 bases:

>100_bases
ATTAAGTTCATGTTAGAAAAAGATACGTAAAAAATCCATTTACTCCATTTGCGGATCTCATTATGATGCGCGCATCTATG
ACTATTGGAATGCCGCTAAG

Downstream 100 bases:

>100_bases
TAAGCAGTAAGCAACTAGTTCGTTTATTTATATCAGGCTTATTCTGAACTCGCTTGCAAAGAATCCACCTTCTGAAGAAG
GTGGCTTTGCTATCTGTTCC

Product: purine phosphorylase family 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRTTLAIFALLYPLFSINAFANTNSDVKPVSKTPTEIKSQTIAILGAMDAEIEKLLPEIKQRQTHTIAKNTYYTGVIQGK
PVVVARSGVGKVNAAITTYVLINHFDVNSIIFTGIAGAAGPDLNVADVVISTALVQHDVDLTAFGAPKGLLDGYDDRLFY
ADKKLQALALNAAVESVGKARVHTGIIATGDQFIADKAVVSMLLKEFSAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKA
DGSAHLVYEEAKQVTADNSVAITLNMLSQM

Sequences:

>Translated_270_residues
MRTTLAIFALLYPLFSINAFANTNSDVKPVSKTPTEIKSQTIAILGAMDAEIEKLLPEIKQRQTHTIAKNTYYTGVIQGK
PVVVARSGVGKVNAAITTYVLINHFDVNSIIFTGIAGAAGPDLNVADVVISTALVQHDVDLTAFGAPKGLLDGYDDRLFY
ADKKLQALALNAAVESVGKARVHTGIIATGDQFIADKAVVSMLLKEFSAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKA
DGSAHLVYEEAKQVTADNSVAITLNMLSQM
>Mature_270_residues
MRTTLAIFALLYPLFSINAFANTNSDVKPVSKTPTEIKSQTIAILGAMDAEIEKLLPEIKQRQTHTIAKNTYYTGVIQGK
PVVVARSGVGKVNAAITTYVLINHFDVNSIIFTGIAGAAGPDLNVADVVISTALVQHDVDLTAFGAPKGLLDGYDDRLFY
ADKKLQALALNAAVESVGKARVHTGIIATGDQFIADKAVVSMLLKEFSAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKA
DGSAHLVYEEAKQVTADNSVAITLNMLSQM

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=36.9565217391304, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 28767; Mature: 28767

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTLAIFALLYPLFSINAFANTNSDVKPVSKTPTEIKSQTIAILGAMDAEIEKLLPEIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEECCHHHHHHHHHHHH
QRQTHTIAKNTYYTGVIQGKPVVVARSGVGKVNAAITTYVLINHFDVNSIIFTGIAGAAG
HHHHHHHHCCCEEEEEECCCEEEEEECCCCCHHHHEEEEEEEEECCCHHHHEECCCCCCC
PDLNVADVVISTALVQHDVDLTAFGAPKGLLDGYDDRLFYADKKLQALALNAAVESVGKA
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
RVHTGIIATGDQFIADKAVVSMLLKEFSAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKA
HHHCCEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCHHEEEEECCCCC
DGSAHLVYEEAKQVTADNSVAITLNMLSQM
CCCEEEEEHHHHHHCCCCCEEEEEEEHHCC
>Mature Secondary Structure
MRTTLAIFALLYPLFSINAFANTNSDVKPVSKTPTEIKSQTIAILGAMDAEIEKLLPEIK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEECCHHHHHHHHHHHH
QRQTHTIAKNTYYTGVIQGKPVVVARSGVGKVNAAITTYVLINHFDVNSIIFTGIAGAAG
HHHHHHHHCCCEEEEEECCCEEEEEECCCCCHHHHEEEEEEEEECCCHHHHEECCCCCCC
PDLNVADVVISTALVQHDVDLTAFGAPKGLLDGYDDRLFYADKKLQALALNAAVESVGKA
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
RVHTGIIATGDQFIADKAVVSMLLKEFSAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKA
HHHCCEEECCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCHHEEEEECCCCC
DGSAHLVYEEAKQVTADNSVAITLNMLSQM
CCCEEEEEHHHHHHCCCCCEEEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA