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The map label for this gene is lolC [H]

Identifier: 157961371

GI number: 157961371

Start: 1881397

End: 1882620

Strand: Direct

Name: lolC [H]

Synonym: Spea_1545

Alternate gene names: 157961371

Gene position: 1881397-1882620 (Clockwise)

Preceding gene: 157961367

Following gene: 157961372

Centisome position: 36.36

GC content: 49.26

Gene sequence:

>1224_bases
ATGAATCTTTCATTATCGTTTTATATTGGTTATCGCTACTGGCGATCCCGTAAAGCCAACGCATTCGCATCATTTATTAC
TATTTTTTCTGTTTCTGGCATTTTACTCGGTGTAGCGGCATTGATTGTGGTCAGTTCGGTGATGAATGGCTTAGAGAACC
AGCTTAAACAACGAATTTTAGGGGCTGTGCCGCAATTAACCGTGCACTCGCAAACGGCCATCGAGAATTGGCCAAGCCAA
GTGGAGAAACTAAGCCAACTTCCGGGCGTTCAGGGCGCAACCCCAAGTATATCGACCCAAGCCATGGTGCAGTCGCCGAG
TAATATAGGCGCCGCGCAGGTGTATGGCATCTATCCTGAGCAGGAAAAAACACTACTAAATACCACTAAGCGAGTTTACT
CGGGAGATTTTGATGCCTTAGAGTCGGGGAAATACCGGGTTATTTTAGGCGCTGAGTTAGCCCGAACACTCGACGTTGCG
CCTGGGGATAAAATTCGAATTCTTAGTGGTGATGGCGTTGTGTATACGCCATTGGGGCCGGTGCCGAGTCAACGTAAGTT
CACCGTGGCGGGTGTTTTTGAAATGGGCTCACAAGTCGATGCGACTCTGGCCTATGTTCATCATGATGATGCTCAGCGAC
TGATGCGTCAAAAGGCGGGAGAGGTCAAGGAGCTGCGTCTATATCTCGATGATCCTTTCAATGCCGCCAAAATGGCGCCA
GAGGTCGTTGCGCAATTTGCCACTCCCGTGACGACGACCGATTGGCGTGACACCTATGGACATCTGTTTGGGGCGGTGAA
GATGGAAAAGAACATGATGTCTTTGATGCTTAGTCTCATTATTGCCGTTGCAGCCTTTAATATCGTTTCCGCCCTGGTGA
TGATGGTGGTGGATAAAACTACGGATGTTGCGGTACTCAAGACCCAAGGTCTGACGACGGCGAATGTGATGGGCATTTTT
ATGATCCAAGGCTCACTCAACGCGGTCATAGGTCTTATATCCGGCGTGGCAGTCGGCAGTTTATTAACCCTCAACCTCAA
CACCATAACTCAGGCTCTTGGGATCTCTATCTTGGGTGCAGGGCAGAATCTGCCTGTTCAACTTGAGTTGAGTCAATTGA
CTTGGATTGTTGTCGGCACCTTAGTGATGACATTGGTGGCCACTGTTTATCCTGCAATTAGAGCGGCTAATGTGCAGCCA
GCGGCCGCACTCAGGTATGAGTAG

Upstream 100 bases:

>100_bases
TGAAGCCTTGAGTAATACTTGTCTCGTTTCAGTCGCCGTTAACACAAAGTTATAATGGCAATTGAGCTCTGCATCATTTG
ATTTTATTTAGGTTTTTTTA

Downstream 100 bases:

>100_bases
CTTAGATACGAGCAGCGGGGATATGAGTAAGCGGCGATATGAATAAGCCAGAATACAAATTAGCGGTGATACGAGTCGGC
CACGAATAAGATATGAATAG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNLSLSFYIGYRYWRSRKANAFASFITIFSVSGILLGVAALIVVSSVMNGLENQLKQRILGAVPQLTVHSQTAIENWPSQ
VEKLSQLPGVQGATPSISTQAMVQSPSNIGAAQVYGIYPEQEKTLLNTTKRVYSGDFDALESGKYRVILGAELARTLDVA
PGDKIRILSGDGVVYTPLGPVPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEVKELRLYLDDPFNAAKMAP
EVVAQFATPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLTTANVMGIF
MIQGSLNAVIGLISGVAVGSLLTLNLNTITQALGISILGAGQNLPVQLELSQLTWIVVGTLVMTLVATVYPAIRAANVQP
AAALRYE

Sequences:

>Translated_407_residues
MNLSLSFYIGYRYWRSRKANAFASFITIFSVSGILLGVAALIVVSSVMNGLENQLKQRILGAVPQLTVHSQTAIENWPSQ
VEKLSQLPGVQGATPSISTQAMVQSPSNIGAAQVYGIYPEQEKTLLNTTKRVYSGDFDALESGKYRVILGAELARTLDVA
PGDKIRILSGDGVVYTPLGPVPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEVKELRLYLDDPFNAAKMAP
EVVAQFATPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLTTANVMGIF
MIQGSLNAVIGLISGVAVGSLLTLNLNTITQALGISILGAGQNLPVQLELSQLTWIVVGTLVMTLVATVYPAIRAANVQP
AAALRYE
>Mature_407_residues
MNLSLSFYIGYRYWRSRKANAFASFITIFSVSGILLGVAALIVVSSVMNGLENQLKQRILGAVPQLTVHSQTAIENWPSQ
VEKLSQLPGVQGATPSISTQAMVQSPSNIGAAQVYGIYPEQEKTLLNTTKRVYSGDFDALESGKYRVILGAELARTLDVA
PGDKIRILSGDGVVYTPLGPVPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEVKELRLYLDDPFNAAKMAP
EVVAQFATPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLTTANVMGIF
MIQGSLNAVIGLISGVAVGSLLTLNLNTITQALGISILGAGQNLPVQLELSQLTWIVVGTLVMTLVATVYPAIRAANVQP
AAALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=404, Percent_Identity=42.3267326732673, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1787362, Length=413, Percent_Identity=32.6876513317191, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43770; Mature: 43770

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSLSFYIGYRYWRSRKANAFASFITIFSVSGILLGVAALIVVSSVMNGLENQLKQRIL
CCEEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTVHSQTAIENWPSQVEKLSQLPGVQGATPSISTQAMVQSPSNIGAAQVYGIYPE
HCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCC
QEKTLLNTTKRVYSGDFDALESGKYRVILGAELARTLDVAPGDKIRILSGDGVVYTPLGP
HHHHHHHHHHHHHCCCCHHHCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCEEECCCCC
VPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEVKELRLYLDDPFNAAKMAP
CCCCCEEEEEEHHHCCCCCCCEEEEEECHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCH
EVVAQFATPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDVAVLKTQGLTTANVMGIFMIQGSLNAVIGLISGVAVGSLLTLNLNTITQALGISILGA
CCEEEEEECCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHCCEEEEC
GQNLPVQLELSQLTWIVVGTLVMTLVATVYPAIRAANVQPAAALRYE
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNLSLSFYIGYRYWRSRKANAFASFITIFSVSGILLGVAALIVVSSVMNGLENQLKQRIL
CCEEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTVHSQTAIENWPSQVEKLSQLPGVQGATPSISTQAMVQSPSNIGAAQVYGIYPE
HCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCC
QEKTLLNTTKRVYSGDFDALESGKYRVILGAELARTLDVAPGDKIRILSGDGVVYTPLGP
HHHHHHHHHHHHHCCCCHHHCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCEEECCCCC
VPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEVKELRLYLDDPFNAAKMAP
CCCCCEEEEEEHHHCCCCCCCEEEEEECHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCH
EVVAQFATPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDVAVLKTQGLTTANVMGIFMIQGSLNAVIGLISGVAVGSLLTLNLNTITQALGISILGA
CCEEEEEECCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHCCEEEEC
GQNLPVQLELSQLTWIVVGTLVMTLVATVYPAIRAANVQPAAALRYE
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]