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The map label for this gene is sdaA [H]

Identifier: 157961364

GI number: 157961364

Start: 1872055

End: 1873431

Strand: Reverse

Name: sdaA [H]

Synonym: Spea_1538

Alternate gene names: 157961364

Gene position: 1873431-1872055 (Counterclockwise)

Preceding gene: 157961368

Following gene: 157961362

Centisome position: 36.2

GC content: 47.64

Gene sequence:

>1377_bases
ATGATTAGTGTATTCGACATGTTCAAAATCGGCATCGGGCCGTCAAGTTCTCATACTGTAGGTCCAATGAAAGCGGGCAA
CGTTTTTATTGAGCAACTGCAGCAGTTAAATATTCTCGATAGCGTTGATGAATTACGTTCAGAGCTGTTTGGCTCTTTAG
GGCAAACAGGGGTAGGTCACGGCACTGGCAAAGCCGTCATTTTAGGGCTTATGGGAGAGGCGCCAGAATCAGTAGATACT
GACAGCATTGATGCCATTTTAGAGCAAGTAAAAAACACCGGGCTGCTAACACTTGCAAGCGGACGAAAAGTACTCTTTAC
TCGCGCAGACGGTATCACCTACCACAGGCGCAAAAGCCTGCCAGCTCATGCCAATGCCATGACCTTATATGCCTATAAAG
ACGGCGAGTGCATCTATGATCGCACCTATTACTCTGTAGGGGGTGGCTTCATTCTCGATGAAGATGAAATCAAAGCACAA
GATGCATCCCCGGCAGCACCGATTCAATCAGCCCCTTTTGACTTTGATTCAGCGCAACAACTGCTTGAGCTCTGTACTGA
AAATGGTTTCAGCATTTCATCACTTATGATGATGAATGAACTTAGCATTGCCGACGCCGACGAGATCAATGATCAATTGT
GGCAAATCTGGCAAACCATGAAGACCTGTGTTGAGCGCGGTTACCAAAAGGAAGGCATCCTTCCTGGAGGCTTAAAACTG
AGACGCCGTGCACCTTCGCTACATCGTCGTTTAAAAGCCGAAGGCAAGAACTGCGTCGATCCGCTAACCGCTATGGATTG
GGTCGACCTATTTGCCCTATCAGTTAACGAGCAAAATGCCGCTGGCGATCGTGTTGTTACCGCACCGACTAACGGCGCAG
CAGGGATTATTCCTGCGGTATTATGTTATTACGACATGTTCGTTCAAGAAGTTGACCAAGACGTTTGCAATCGCTATCTA
CTGACGGCTGCTGCCATTGGTATTCTTTATAAGAAGAATGCTTCTATCTCTGGCGCTGAAGTGGGTTGCCAGGGGGAAGT
TGGCGTAGCTTGCTCTATGGCTGCAGCGGCTCTGACTGAGATCATGGGCGGCACTGTTGAACATGTTGAGAATGCAGCTG
AAATCGGCATGGAGCATAACCTAGGCTTAACTTGTGACCCTGTAGGCGGCCTTGTACAAGTTCCTTGTATTGAACGTAAT
GCTATGGGGGCGGTAAAAGCGATTAACGCTTCACGTATGGCAATGCGCGGCGATGGTAACCATAAAGTCTCACTCGATAA
GGTGATTAAGACCATGATGGATACAGGTAAAGATATGCGTAGTAAGTATAAAGAGACTGCCAAAGGTGGTCTTGCGGTGA
ATATCGTCGAGTGCTAA

Upstream 100 bases:

>100_bases
CAATAAGTGAAATATACCAAGATAATGGGTATTCCTCCATTACCTCATCTCTTAGTGAAGTTGGTCATAACTATAACGAC
TAGAGCAATAAAGGTTTAGC

Downstream 100 bases:

>100_bases
TTACTGTCTTTGGGCTCACTTTTTACCAAAGCACTTAAAAACAAAAACCTCGCTATTGCGAGGTTTTTTATTATCAGTGA
CAGCTCTCAGTATAACTACC

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGNVFIEQLQQLNILDSVDELRSELFGSLGQTGVGHGTGKAVILGLMGEAPESVDT
DSIDAILEQVKNTGLLTLASGRKVLFTRADGITYHRRKSLPAHANAMTLYAYKDGECIYDRTYYSVGGGFILDEDEIKAQ
DASPAAPIQSAPFDFDSAQQLLELCTENGFSISSLMMMNELSIADADEINDQLWQIWQTMKTCVERGYQKEGILPGGLKL
RRRAPSLHRRLKAEGKNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDQDVCNRYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRMAMRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC

Sequences:

>Translated_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGNVFIEQLQQLNILDSVDELRSELFGSLGQTGVGHGTGKAVILGLMGEAPESVDT
DSIDAILEQVKNTGLLTLASGRKVLFTRADGITYHRRKSLPAHANAMTLYAYKDGECIYDRTYYSVGGGFILDEDEIKAQ
DASPAAPIQSAPFDFDSAQQLLELCTENGFSISSLMMMNELSIADADEINDQLWQIWQTMKTCVERGYQKEGILPGGLKL
RRRAPSLHRRLKAEGKNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDQDVCNRYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRMAMRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
>Mature_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGNVFIEQLQQLNILDSVDELRSELFGSLGQTGVGHGTGKAVILGLMGEAPESVDT
DSIDAILEQVKNTGLLTLASGRKVLFTRADGITYHRRKSLPAHANAMTLYAYKDGECIYDRTYYSVGGGFILDEDEIKAQ
DASPAAPIQSAPFDFDSAQQLLELCTENGFSISSLMMMNELSIADADEINDQLWQIWQTMKTCVERGYQKEGILPGGLKL
RRRAPSLHRRLKAEGKNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDQDVCNRYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRMAMRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=459, Percent_Identity=56.6448801742919, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI1789161, Length=458, Percent_Identity=54.1484716157205, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=55.0218340611354, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49220; Mature: 49220

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGNVFIEQLQQLNILDSVDELRSELFGSLGQTGVGH
CCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEAPESVDTDSIDAILEQVKNTGLLTLASGRKVLFTRADGITYHRRKSL
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCEEHHHCCC
PAHANAMTLYAYKDGECIYDRTYYSVGGGFILDEDEIKAQDASPAAPIQSAPFDFDSAQQ
CCCCCEEEEEEEECCCEEEECCEEECCCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHH
LLELCTENGFSISSLMMMNELSIADADEINDQLWQIWQTMKTCVERGYQKEGILPGGLKL
HHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPSLHRRLKAEGKNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDMFVQEVDQDVCNRYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRMAMRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHCCHHHHEEECCCC
HKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGNVFIEQLQQLNILDSVDELRSELFGSLGQTGVGH
CCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEAPESVDTDSIDAILEQVKNTGLLTLASGRKVLFTRADGITYHRRKSL
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCEEHHHCCC
PAHANAMTLYAYKDGECIYDRTYYSVGGGFILDEDEIKAQDASPAAPIQSAPFDFDSAQQ
CCCCCEEEEEEEECCCEEEECCEEECCCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHH
LLELCTENGFSISSLMMMNELSIADADEINDQLWQIWQTMKTCVERGYQKEGILPGGLKL
HHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPSLHRRLKAEGKNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDMFVQEVDQDVCNRYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRMAMRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHCCHHHHEEECCCC
HKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]