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The map label for this gene is gsk [H]

Identifier: 157961356

GI number: 157961356

Start: 1859148

End: 1860476

Strand: Direct

Name: gsk [H]

Synonym: Spea_1530

Alternate gene names: 157961356

Gene position: 1859148-1860476 (Clockwise)

Preceding gene: 157961355

Following gene: 157961357

Centisome position: 35.93

GC content: 45.45

Gene sequence:

>1329_bases
ATGCCGAATGAAAGAGAGCTCAATATGAAGTTTCCAGGTCAGCGTAAGTCTAAACATTATTTTCCAGTTAAAAACCGCGA
TCCACTGCTTGCACAGTTGATCCAACAGCCTCTACCGATTTCAACCTACATCTCTGGTATCGATCAGACGCTTGTAGACA
TTGAGGCGAAAGTGGAAGATGAGTTATTGAGCCGCTACGAGCTGCCTAAAGGCAACTCAACCTTGATCGATGATGACAAG
GCCCATGCACTTTATACTGAGCTTAAAAGCAATGAATTGATCAGCGACGAGTTTGCTGGTGGCACTATCGGTAACACAGT
ACATAACTACTCAATTCTAGCCGATGACCGCTCTGTGTTATTTGGCGTAATGAGCAAAAACATTGAGGTGGGGAGCTATG
CATATCGCTACCTTTGTAATACTTCTTCTAAAGTTGATCTAAACTATTTGCAACCTGTAGCGGGTCCAATTGGTCGCTGT
TTCACTCTTATTTCAGAATGCGGTGAGCGTACTTTTGCCATCAGTAAAGGCTCAATGGATCAGCTTACACCTGAATATAT
CGATAAAGAGGTGGTTCAAGGTGGATCGGCGCTCATTCTAACCGCCTACTTAATGCGCGCCAGTGGTGATGATCAGATAA
CTGAAGCTGCGATGACGGCAATCAGTTACGCTAAAGAAGCAGAGGTGCCTGTTGTTCTGACACTAGGTACGCGTTTCTTA
ATCGAAGAAGATCCAAAATGGTGGCAGGAGTTCATCAAAGAGCACGTGACTATTTTGGCGATGAATGAAGATGAAGGTGA
AGCATTAACAGGCTTTAGTGATCCACTGCAAGCCAGTGAAGCTGCGCTTGAGTGGTGTGACATGGTATTGACTACAGCGG
GTCCTTTAGGTCTTTACACTGCAGGTTACACAGAAGACTCAGAAAAGCGTGAAACTAGCCATACCTTGCTGCCAGGTTCA
ATTCCTGAGTTTAACCGCTACGAGTTCTCTCGTCCTAAATTAAAGGCTGATTGCGATTCACCTTTAAAGGTGTACGCGCA
TATCTCTCCTTATATGGGGGGGCCAGAGATTATTCGTAACACTAACGGTGCAGGCGATGGTGCATTAGCAGCTTTGCTGC
ACGACTTAGCGTCAAATACTTTCCATAAGACCAATGTTCCGGGTTCGAGCAAGCATAAGCGTGATGGTTTGTGTTACTCA
TCGTTCTCGCAAATTTGTAAGTATGCTAACCGCGTGGCTTATGAAGTGCTGGCTCAACATAGCCCACGACTCTCTCGAGG
CCTACCAGAGCGTGAAGACAGCTTAGAAGAGTCATACTGGGAAAGATAA

Upstream 100 bases:

>100_bases
GTTTTTATTATGGCCAGTTGCTAGAAGTGCAGAGTTTGCTTGTTCGTATTGAATAAACAGCTTGAGATAACTTACCCGTT
TTAATTTATATTTTGCATGG

Downstream 100 bases:

>100_bases
CCCTAAGTAGCGCCTATAGGCGGCTATAAGCAATATAAAGGCATAACTTGGTGATCAGGTTATGCCTTTTTTGAATCTAC
TCTAACATAACAATAAAAAA

Product: inosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPNERELNMKFPGQRKSKHYFPVKNRDPLLAQLIQQPLPISTYISGIDQTLVDIEAKVEDELLSRYELPKGNSTLIDDDK
AHALYTELKSNELISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKNIEVGSYAYRYLCNTSSKVDLNYLQPVAGPIGRC
FTLISECGERTFAISKGSMDQLTPEYIDKEVVQGGSALILTAYLMRASGDDQITEAAMTAISYAKEAEVPVVLTLGTRFL
IEEDPKWWQEFIKEHVTILAMNEDEGEALTGFSDPLQASEAALEWCDMVLTTAGPLGLYTAGYTEDSEKRETSHTLLPGS
IPEFNRYEFSRPKLKADCDSPLKVYAHISPYMGGPEIIRNTNGAGDGALAALLHDLASNTFHKTNVPGSSKHKRDGLCYS
SFSQICKYANRVAYEVLAQHSPRLSRGLPEREDSLEESYWER

Sequences:

>Translated_442_residues
MPNERELNMKFPGQRKSKHYFPVKNRDPLLAQLIQQPLPISTYISGIDQTLVDIEAKVEDELLSRYELPKGNSTLIDDDK
AHALYTELKSNELISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKNIEVGSYAYRYLCNTSSKVDLNYLQPVAGPIGRC
FTLISECGERTFAISKGSMDQLTPEYIDKEVVQGGSALILTAYLMRASGDDQITEAAMTAISYAKEAEVPVVLTLGTRFL
IEEDPKWWQEFIKEHVTILAMNEDEGEALTGFSDPLQASEAALEWCDMVLTTAGPLGLYTAGYTEDSEKRETSHTLLPGS
IPEFNRYEFSRPKLKADCDSPLKVYAHISPYMGGPEIIRNTNGAGDGALAALLHDLASNTFHKTNVPGSSKHKRDGLCYS
SFSQICKYANRVAYEVLAQHSPRLSRGLPEREDSLEESYWER
>Mature_441_residues
PNERELNMKFPGQRKSKHYFPVKNRDPLLAQLIQQPLPISTYISGIDQTLVDIEAKVEDELLSRYELPKGNSTLIDDDKA
HALYTELKSNELISDEFAGGTIGNTVHNYSILADDRSVLFGVMSKNIEVGSYAYRYLCNTSSKVDLNYLQPVAGPIGRCF
TLISECGERTFAISKGSMDQLTPEYIDKEVVQGGSALILTAYLMRASGDDQITEAAMTAISYAKEAEVPVVLTLGTRFLI
EEDPKWWQEFIKEHVTILAMNEDEGEALTGFSDPLQASEAALEWCDMVLTTAGPLGLYTAGYTEDSEKRETSHTLLPGSI
PEFNRYEFSRPKLKADCDSPLKVYAHISPYMGGPEIIRNTNGAGDGALAALLHDLASNTFHKTNVPGSSKHKRDGLCYSS
FSQICKYANRVAYEVLAQHSPRLSRGLPEREDSLEESYWER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=67.9723502304147, Blast_Score=630, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 49183; Mature: 49052

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNERELNMKFPGQRKSKHYFPVKNRDPLLAQLIQQPLPISTYISGIDQTLVDIEAKVED
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ELLSRYELPKGNSTLIDDDKAHALYTELKSNELISDEFAGGTIGNTVHNYSILADDRSVL
HHHHHHCCCCCCCCEECCCCHHHHHHHHHCCCCCCHHCCCCCCCCCHHCEEEEECCHHHH
FGVMSKNIEVGSYAYRYLCNTSSKVDLNYLQPVAGPIGRCFTLISECGERTFAISKGSMD
HHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHH
QLTPEYIDKEVVQGGSALILTAYLMRASGDDQITEAAMTAISYAKEAEVPVVLTLGTRFL
HCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCEEE
IEEDPKWWQEFIKEHVTILAMNEDEGEALTGFSDPLQASEAALEWCDMVLTTAGPLGLYT
EECCHHHHHHHHHCCEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
AGYTEDSEKRETSHTLLPGSIPEFNRYEFSRPKLKADCDSPLKVYAHISPYMGGPEIIRN
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHCC
TNGAGDGALAALLHDLASNTFHKTNVPGSSKHKRDGLCYSSFSQICKYANRVAYEVLAQH
CCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
SPRLSRGLPEREDSLEESYWER
CCHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PNERELNMKFPGQRKSKHYFPVKNRDPLLAQLIQQPLPISTYISGIDQTLVDIEAKVED
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ELLSRYELPKGNSTLIDDDKAHALYTELKSNELISDEFAGGTIGNTVHNYSILADDRSVL
HHHHHHCCCCCCCCEECCCCHHHHHHHHHCCCCCCHHCCCCCCCCCHHCEEEEECCHHHH
FGVMSKNIEVGSYAYRYLCNTSSKVDLNYLQPVAGPIGRCFTLISECGERTFAISKGSMD
HHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHH
QLTPEYIDKEVVQGGSALILTAYLMRASGDDQITEAAMTAISYAKEAEVPVVLTLGTRFL
HCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCEEE
IEEDPKWWQEFIKEHVTILAMNEDEGEALTGFSDPLQASEAALEWCDMVLTTAGPLGLYT
EECCHHHHHHHHHCCEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
AGYTEDSEKRETSHTLLPGSIPEFNRYEFSRPKLKADCDSPLKVYAHISPYMGGPEIIRN
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHCC
TNGAGDGALAALLHDLASNTFHKTNVPGSSKHKRDGLCYSSFSQICKYANRVAYEVLAQH
CCCCCHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
SPRLSRGLPEREDSLEESYWER
CCHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]