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The map label for this gene is nanK [H]

Identifier: 157961346

GI number: 157961346

Start: 1847348

End: 1848220

Strand: Direct

Name: nanK [H]

Synonym: Spea_1520

Alternate gene names: 157961346

Gene position: 1847348-1848220 (Clockwise)

Preceding gene: 157961345

Following gene: 157961347

Centisome position: 35.7

GC content: 45.02

Gene sequence:

>873_bases
ATGATTATCACAATTGATGTTGGCGGCACCAAGATATCGGCTGCGTTAATCAAGGGGACTAAAGTCATTAAGGTTAGGAA
AGTTGATTCAATTATCCATCAAGACTTAGCTAACCTTGCAAGTTACCTTGTTAACTTATGTGAAGGTTGGGCAGAGCAGG
CGTTTACGGTTGCGGTAGCCTGTACTGGGCTTGTGGGAGCAGAGCGAGTTAACTTTTTATCTGCAAACGATTCGCTACCG
CTAAAGCAGCAACTTGAAATAGGCTTTGGTTTACCTGTTGTTATGTTAAACGATGCTGCCGCTGCAGCCTGGGCTGAATA
TACCTTAAGGCTTGATAGAACAGACAATACTTTGGCCTACATTACCGTTTCAACCGGTGTGGGTGGTGGCATTGTTCAAA
ATGGCAAGTTAGTGATGGCCGATGATGGGTTTTGTGCGCACATTGGGCATATGTCAGTTAGTCGGCCAGACTTGCCTGTA
ATTGAGTGTCATTGTGGCAGGTTTAACTGTGTAGAGGCCCTATCTTCAGGGACGGCTATCGCTAATCAAGCGTCAAGTAT
TTTAAATAAAGGTGTTAGCTGCAAAACCGTTTTTAATGAGCATTTATCCCATCCAGAAATAGCCCTGTTACTAGAGCAGG
CAACTGATAGCATTGTTGAGCTTATCGCTAACATTAGAGCCTTAACAGGAACACGAGTCGTGGTGTTAGGCGGCAGTGTC
GGCTCTACAAACTTATTCCAAGAGCGAATAAAAACCAAATTAAAGGCACTTCCTAAAATCTACCACGTCGAACTCCTTGC
CCCTGTCTCTGGAGAGCATGCCGACCTTATTGGCGCAGCTTTGTACGCCGGTTCGGTAATCGGTTGTGATTAA

Upstream 100 bases:

>100_bases
AACACATTACTCAGTGGTTTGTCGCTGGTGTTGAAGCCGGTGGTAATACTAGTACCGTCGAGAATGAAAATGCCCAAGAT
GGTATAGGAGCCTTGGCTAC

Downstream 100 bases:

>100_bases
TAGATGCCAGTGTTTTACCTTGATATTGTGATTAATAGATGCCGGTGTTTTACCTTGATATTGTGATTAATGATGCCTGT
GTTTTACCTTGATATTGGAA

Product: ROK family protein

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MIITIDVGGTKISAALIKGTKVIKVRKVDSIIHQDLANLASYLVNLCEGWAEQAFTVAVACTGLVGAERVNFLSANDSLP
LKQQLEIGFGLPVVMLNDAAAAAWAEYTLRLDRTDNTLAYITVSTGVGGGIVQNGKLVMADDGFCAHIGHMSVSRPDLPV
IECHCGRFNCVEALSSGTAIANQASSILNKGVSCKTVFNEHLSHPEIALLLEQATDSIVELIANIRALTGTRVVVLGGSV
GSTNLFQERIKTKLKALPKIYHVELLAPVSGEHADLIGAALYAGSVIGCD

Sequences:

>Translated_290_residues
MIITIDVGGTKISAALIKGTKVIKVRKVDSIIHQDLANLASYLVNLCEGWAEQAFTVAVACTGLVGAERVNFLSANDSLP
LKQQLEIGFGLPVVMLNDAAAAAWAEYTLRLDRTDNTLAYITVSTGVGGGIVQNGKLVMADDGFCAHIGHMSVSRPDLPV
IECHCGRFNCVEALSSGTAIANQASSILNKGVSCKTVFNEHLSHPEIALLLEQATDSIVELIANIRALTGTRVVVLGGSV
GSTNLFQERIKTKLKALPKIYHVELLAPVSGEHADLIGAALYAGSVIGCD
>Mature_290_residues
MIITIDVGGTKISAALIKGTKVIKVRKVDSIIHQDLANLASYLVNLCEGWAEQAFTVAVACTGLVGAERVNFLSANDSLP
LKQQLEIGFGLPVVMLNDAAAAAWAEYTLRLDRTDNTLAYITVSTGVGGGIVQNGKLVMADDGFCAHIGHMSVSRPDLPV
IECHCGRFNCVEALSSGTAIANQASSILNKGVSCKTVFNEHLSHPEIALLLEQATDSIVELIANIRALTGTRVVVLGGSV
GSTNLFQERIKTKLKALPKIYHVELLAPVSGEHADLIGAALYAGSVIGCD

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082230, Length=272, Percent_Identity=37.8676470588235, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 30563; Mature: 30563

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITIDVGGTKISAALIKGTKVIKVRKVDSIIHQDLANLASYLVNLCEGWAEQAFTVAVA
CEEEEECCCCEEEHEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEH
CTGLVGAERVNFLSANDSLPLKQQLEIGFGLPVVMLNDAAAAAWAEYTLRLDRTDNTLAY
HHCCCCHHHEEEEECCCCCCCHHHHHCCCCCCEEEECCCHHHHHEEEEEEEECCCCEEEE
ITVSTGVGGGIVQNGKLVMADDGFCAHIGHMSVSRPDLPVIECHCGRFNCVEALSSGTAI
EEEECCCCCCEEECCEEEEECCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHCCCHH
ANQASSILNKGVSCKTVFNEHLSHPEIALLLEQATDSIVELIANIRALTGTRVVVLGGSV
HHHHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GSTNLFQERIKTKLKALPKIYHVELLAPVSGEHADLIGAALYAGSVIGCD
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCEEECCC
>Mature Secondary Structure
MIITIDVGGTKISAALIKGTKVIKVRKVDSIIHQDLANLASYLVNLCEGWAEQAFTVAVA
CEEEEECCCCEEEHEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEH
CTGLVGAERVNFLSANDSLPLKQQLEIGFGLPVVMLNDAAAAAWAEYTLRLDRTDNTLAY
HHCCCCHHHEEEEECCCCCCCHHHHHCCCCCCEEEECCCHHHHHEEEEEEEECCCCEEEE
ITVSTGVGGGIVQNGKLVMADDGFCAHIGHMSVSRPDLPVIECHCGRFNCVEALSSGTAI
EEEECCCCCCEEECCEEEEECCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHCCCHH
ANQASSILNKGVSCKTVFNEHLSHPEIALLLEQATDSIVELIANIRALTGTRVVVLGGSV
HHHHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GSTNLFQERIKTKLKALPKIYHVELLAPVSGEHADLIGAALYAGSVIGCD
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA