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The map label for this gene is hscB [H]

Identifier: 157961317

GI number: 157961317

Start: 1811882

End: 1812406

Strand: Direct

Name: hscB [H]

Synonym: Spea_1491

Alternate gene names: 157961317

Gene position: 1811882-1812406 (Clockwise)

Preceding gene: 157961316

Following gene: 157961318

Centisome position: 35.02

GC content: 43.62

Gene sequence:

>525_bases
ATGAATTATTTCGAGCTGTTTAGTTTACTTCCTTCCTATGATGTCGACACCGCCTTACTTGCAGATCGCTACCGCGAACT
GCAAAGGGCGGTTCATCCTGACAAATTTGCTAACGCAAGTGAGCAAGATAAACGTCTTTCTGTGCAGCGTACCGCACAAA
TCAATGATGCTTTTCAAACACTCAAAAATCCCATTCAAAGAGCCGAGCATTTGCTTGCGTTGAAAGGGCTAGAGTTAAGC
CACGAATCTACCACATTGAAAGATACTCAATTTTTAATGCAGCAGATGGATTGGCGAGAGTCACTTGAAGAGATCAAGCA
TAGCGATGATCCCGACTCTGAGATTGCCGAGCTCTACGATTCCTTCGAGCAATACGCTAAGCACATTACTGCAGAGTTAA
AGCTTTTGCTGGTGAGTGAGCTTGAAGCAGACCATTTGCAGGCGGCAGATCAAATTCGTAAACTTAAGTTTATGGCAAAA
TTACAAGATGAGTTGACCAGAGTGGAAGACGCACTCTTAGATTAG

Upstream 100 bases:

>100_bases
AGAAGGTCTAAACGAAGGTTTCCAATTTAATAACCCTAATGCGAAAGGTGAATGTGGCTGCGGTGAGAGTTTTACCGTAT
AAGCCATTAAAAGTTAAACT

Downstream 100 bases:

>100_bases
TCAACGGTCTTAATTTTTAATACTGTTGGCTCAAGACATTGAGCCAACATTTTTTTAAGTTGGATATATATGGCACTTTT
GCAGATAGCAGAGCCTGGAC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFSLLPSYDVDTALLADRYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQTLKNPIQRAEHLLALKGLELS
HESTTLKDTQFLMQQMDWRESLEEIKHSDDPDSEIAELYDSFEQYAKHITAELKLLLVSELEADHLQAADQIRKLKFMAK
LQDELTRVEDALLD

Sequences:

>Translated_174_residues
MNYFELFSLLPSYDVDTALLADRYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQTLKNPIQRAEHLLALKGLELS
HESTTLKDTQFLMQQMDWRESLEEIKHSDDPDSEIAELYDSFEQYAKHITAELKLLLVSELEADHLQAADQIRKLKFMAK
LQDELTRVEDALLD
>Mature_174_residues
MNYFELFSLLPSYDVDTALLADRYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQTLKNPIQRAEHLLALKGLELS
HESTTLKDTQFLMQQMDWRESLEEIKHSDDPDSEIAELYDSFEQYAKHITAELKLLLVSELEADHLQAADQIRKLKFMAK
LQDELTRVEDALLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=165, Percent_Identity=32.7272727272727, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1788876, Length=175, Percent_Identity=42.2857142857143, Blast_Score=127, Evalue=6e-31,
Organism=Drosophila melanogaster, GI161084223, Length=131, Percent_Identity=29.7709923664122, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20251; Mature: 20251

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFSLLPSYDVDTALLADRYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQT
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKNPIQRAEHLLALKGLELSHESTTLKDTQFLMQQMDWRESLEEIKHSDDPDSEIAELYD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SFEQYAKHITAELKLLLVSELEADHLQAADQIRKLKFMAKLQDELTRVEDALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFSLLPSYDVDTALLADRYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQT
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
LKNPIQRAEHLLALKGLELSHESTTLKDTQFLMQQMDWRESLEEIKHSDDPDSEIAELYD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SFEQYAKHITAELKLLLVSELEADHLQAADQIRKLKFMAKLQDELTRVEDALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA