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The map label for this gene is cysQ [H]

Identifier: 157961266

GI number: 157961266

Start: 1754834

End: 1755622

Strand: Direct

Name: cysQ [H]

Synonym: Spea_1440

Alternate gene names: 157961266

Gene position: 1754834-1755622 (Clockwise)

Preceding gene: 157961265

Following gene: 157961267

Centisome position: 33.91

GC content: 46.26

Gene sequence:

>789_bases
TTGAACCATGTATTTAAACAGGAGTGGTTAGGACCTCTTCTCGATATTGCGACTGAAGCTGGAGAGGCCATTATGGCCAT
ATATAAGCAGGATGATCTAGGTGTGTTGACTAAGTCTGATGACAGTCCTGTAACGGCAGCTGATTTGGCGAGCCATCAGG
TAATTGTTGAAAGGCTGAAGCAATTAACCCCTGATATCCCTGTCATGTCGGAAGAGTCGACGGATATTGATTGGCAGCAG
AGGCGTCATTGGCAATCATATTGGCTGATTGACCCACTCGATGGCACCAAAGAGTTTATTAAGCGCAATGGCGAGTTCAC
AGTCAATATCGCCTTCATCCACCATGATACCGCCGTCGCAGGCGTTGTATATGCCCCTGTTCTGGATAAATGCTTTTATG
GTGAACTGGAAAGTGGAGCTTGGTTAAAACATGCTGGAGAACGAATCGAGTTACCTAAAGTGAATAGCTCGAAAGCGCTT
GTTCCTCGAATTGTTGGTAGTCGATCTCACGCTAGCCCTGGTTTACAAGCATTCTTGCAAGAGCTTGGCGAGCATGAGAT
GAAGAGTGTTGGTAGTTCGCTTAAGTTTTGTCTTTTGGCTGAAGGAGAGGCCGATATTTACCCAAGGTTGGGGCTAACCA
GTGAGTGGGATACCGCAGCTGCGCAGGCTGTGCTGGAAAGTGCTGGTGGTCGAGTGGTGCAATATGACACTAATATTCCT
CTTAATTACAATCAAAAATCTGACATACTGAATCCCTATTTTATTGCGTATGCGCCACACTGGCATTGA

Upstream 100 bases:

>100_bases
TCTGTTTTCGACATTAAATGATTATTTGGTTATTAATTTTTATCGTTAAATACTGGCATAATGAAGCTATAACCTTCGTA
AATTATAGAGATAACTTACA

Downstream 100 bases:

>100_bases
AGCAAGTTGACTTTAGCTGTGTTGGTGAGAGTAGGCGAGTCTGAGTAAAAGGCTACTCTCGGTTTAAATGTTAAAACGAA
TTAAAAATACTTTTGGAGCG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNHVFKQEWLGPLLDIATEAGEAIMAIYKQDDLGVLTKSDDSPVTAADLASHQVIVERLKQLTPDIPVMSEESTDIDWQQ
RRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHDTAVAGVVYAPVLDKCFYGELESGAWLKHAGERIELPKVNSSKAL
VPRIVGSRSHASPGLQAFLQELGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVVQYDTNIP
LNYNQKSDILNPYFIAYAPHWH

Sequences:

>Translated_262_residues
MNHVFKQEWLGPLLDIATEAGEAIMAIYKQDDLGVLTKSDDSPVTAADLASHQVIVERLKQLTPDIPVMSEESTDIDWQQ
RRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHDTAVAGVVYAPVLDKCFYGELESGAWLKHAGERIELPKVNSSKAL
VPRIVGSRSHASPGLQAFLQELGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVVQYDTNIP
LNYNQKSDILNPYFIAYAPHWH
>Mature_262_residues
MNHVFKQEWLGPLLDIATEAGEAIMAIYKQDDLGVLTKSDDSPVTAADLASHQVIVERLKQLTPDIPVMSEESTDIDWQQ
RRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHDTAVAGVVYAPVLDKCFYGELESGAWLKHAGERIELPKVNSSKAL
VPRIVGSRSHASPGLQAFLQELGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVVQYDTNIP
LNYNQKSDILNPYFIAYAPHWH

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=235, Percent_Identity=28.5106382978723, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221625487, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI7657236, Length=236, Percent_Identity=28.8135593220339, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=51.219512195122, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1788882, Length=238, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995897, Length=269, Percent_Identity=25.2788104089219, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995905, Length=269, Percent_Identity=25.2788104089219, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=254, Percent_Identity=24.8031496062992, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=214, Percent_Identity=27.1028037383178, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24651149, Length=248, Percent_Identity=27.8225806451613, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664922, Length=222, Percent_Identity=26.5765765765766, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357303, Length=154, Percent_Identity=29.8701298701299, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29228; Mature: 29228

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHVFKQEWLGPLLDIATEAGEAIMAIYKQDDLGVLTKSDDSPVTAADLASHQVIVERLK
CCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
QLTPDIPVMSEESTDIDWQQRRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHDTAVA
HHCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCHHHHHHCCCCEEEEEEEEECCCHHH
GVVYAPVLDKCFYGELESGAWLKHAGERIELPKVNSSKALVPRIVGSRSHASPGLQAFLQ
HHHHHHHHHHHHCCCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHH
ELGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVVQYDTNIP
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC
LNYNQKSDILNPYFIAYAPHWH
CCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MNHVFKQEWLGPLLDIATEAGEAIMAIYKQDDLGVLTKSDDSPVTAADLASHQVIVERLK
CCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
QLTPDIPVMSEESTDIDWQQRRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHDTAVA
HHCCCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCHHHHHHCCCCEEEEEEEEECCCHHH
GVVYAPVLDKCFYGELESGAWLKHAGERIELPKVNSSKALVPRIVGSRSHASPGLQAFLQ
HHHHHHHHHHHHCCCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHH
ELGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVVQYDTNIP
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC
LNYNQKSDILNPYFIAYAPHWH
CCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]