Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 157961140

GI number: 157961140

Start: 1597820

End: 1599157

Strand: Reverse

Name: xseA [H]

Synonym: Spea_1312

Alternate gene names: 157961140

Gene position: 1599157-1597820 (Counterclockwise)

Preceding gene: 157961144

Following gene: 157961139

Centisome position: 30.9

GC content: 50.3

Gene sequence:

>1338_bases
ATGAAAACCCCAAAAAATGATGTTTATACCGTCTCTCGTCTCAATGGCGAAGTGAGGCAGCTTTTAGAGGGTCAGCTTGG
CCGGATTTGGTTAAATGCTGAAATTTCAAACTTTGCGGCGCCCGGCTCTGGCCACTGGTATTTAACCCTCAAAGATAATT
TCTCACAAATTCGCTGCGCCATGTTTAAGGGCCGCAACCAAGCGGTAACCTTTCGCCCTGCTAACGGCCAGCAAGTTTTA
GTTAAGGGCAATATCAGCGTGTATGAGCCCCGCGGTGATTATCAATTACTGATTGAATCTATGCTACCAGCAGGAGACGG
TCTGCTAGCTCAGCAATATGAAGCATTGAAGATGAAGCTTGCCGCCGAGGGCCTATTTGCCAGCGACACCAAGCGCCCAC
TTCCCGCCAACATCCAAAAAATTGGTGTGGTCACCTCGCCCACTGGCGCGGCGATTCGCGATATCTTGCATGTATTAGCC
CGCCGCGACTCCTCAATCGAAGTCATCATCTATCCGACTCCCGTACAAGGCAGTGACGCAGCAAAAAGTATTTGCGATGC
CATTAACCTTGCTAACAGCCGCGCCGAAGTTGACGTATTGCTAGTAACCCGAGGCGGGGGCTCGTTAGAGGACTTATGGA
GTTTTAACGACGAAGGACTCGCCCACACCATCTATAACAGTGGCATTCCTGTGGTGTCAGCCGTTGGCCACGAAGTGGAT
ATGACCATCAGCGATTATGTTGCCGATCTGCGCGCGCCAACGCCATCGGCAGGCGCAGAGCTATTATCGAAAGATGCCGA
CAATAAAGCGCAAAAGTTATTATCGCAATTATCTCGCCTCAAGCAAGCTTGGCAGCATTATCAATTAAAGAAACAAAGCC
AAGTTCAAACCATTGAGCATCGTCTACAAAAGCAAGATCCACAGCGCCGACTACAGATGTATGAGCAAAGCTTTGACGAA
ATGCAGCTGCGCCTGCAACAAGCGATGCAAACCAAGTTACATGCTTATGCCTTAAAGCAGCAGAACTTAAGCAGCCGCTT
AGCTAATCAGTCTCCACAGCATAGACTCACCCTCGAAGCCCAGCGTTTGAGTTACCTCAGCGCCAAGCTCAATGACGCCA
TGGATGACAAGTTAAAGATGAGTGAACAGCGCCTTGCCCACCGTGCGCAGCAATTAGACACTGTGAGTCCGTTAGCGACA
TTAAGCCGTGGTTACAGCATTACCCTAACTGGTAGTGGCAAAGTGGTGCAGGCACCATCGGATACTTGTGTGGGCGATAC
GCTGACCACTCGCCTGCGGGATGGCAGTGTGACTTCTACTGTGGTTGAGGTCAGTTAG

Upstream 100 bases:

>100_bases
TAGGAATTAGAGGTGAAATATTGCGGCGAGATTATACCTTGCATATCGGGGTTGGTAAATGGAAAATAGACACTAATTCG
CATTTGTGTGTAAAAAAATT

Downstream 100 bases:

>100_bases
TTCACTTCTATAGCTAATAACAATAGTTTCACTATGGGTTCAAGCTTCGTTTGAAAGTGGCGATTCAAACTTCGTTAGAA
AATTATCGTCGTGGCGCTTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKTPKNDVYTVSRLNGEVRQLLEGQLGRIWLNAEISNFAAPGSGHWYLTLKDNFSQIRCAMFKGRNQAVTFRPANGQQVL
VKGNISVYEPRGDYQLLIESMLPAGDGLLAQQYEALKMKLAAEGLFASDTKRPLPANIQKIGVVTSPTGAAIRDILHVLA
RRDSSIEVIIYPTPVQGSDAAKSICDAINLANSRAEVDVLLVTRGGGSLEDLWSFNDEGLAHTIYNSGIPVVSAVGHEVD
MTISDYVADLRAPTPSAGAELLSKDADNKAQKLLSQLSRLKQAWQHYQLKKQSQVQTIEHRLQKQDPQRRLQMYEQSFDE
MQLRLQQAMQTKLHAYALKQQNLSSRLANQSPQHRLTLEAQRLSYLSAKLNDAMDDKLKMSEQRLAHRAQQLDTVSPLAT
LSRGYSITLTGSGKVVQAPSDTCVGDTLTTRLRDGSVTSTVVEVS

Sequences:

>Translated_445_residues
MKTPKNDVYTVSRLNGEVRQLLEGQLGRIWLNAEISNFAAPGSGHWYLTLKDNFSQIRCAMFKGRNQAVTFRPANGQQVL
VKGNISVYEPRGDYQLLIESMLPAGDGLLAQQYEALKMKLAAEGLFASDTKRPLPANIQKIGVVTSPTGAAIRDILHVLA
RRDSSIEVIIYPTPVQGSDAAKSICDAINLANSRAEVDVLLVTRGGGSLEDLWSFNDEGLAHTIYNSGIPVVSAVGHEVD
MTISDYVADLRAPTPSAGAELLSKDADNKAQKLLSQLSRLKQAWQHYQLKKQSQVQTIEHRLQKQDPQRRLQMYEQSFDE
MQLRLQQAMQTKLHAYALKQQNLSSRLANQSPQHRLTLEAQRLSYLSAKLNDAMDDKLKMSEQRLAHRAQQLDTVSPLAT
LSRGYSITLTGSGKVVQAPSDTCVGDTLTTRLRDGSVTSTVVEVS
>Mature_445_residues
MKTPKNDVYTVSRLNGEVRQLLEGQLGRIWLNAEISNFAAPGSGHWYLTLKDNFSQIRCAMFKGRNQAVTFRPANGQQVL
VKGNISVYEPRGDYQLLIESMLPAGDGLLAQQYEALKMKLAAEGLFASDTKRPLPANIQKIGVVTSPTGAAIRDILHVLA
RRDSSIEVIIYPTPVQGSDAAKSICDAINLANSRAEVDVLLVTRGGGSLEDLWSFNDEGLAHTIYNSGIPVVSAVGHEVD
MTISDYVADLRAPTPSAGAELLSKDADNKAQKLLSQLSRLKQAWQHYQLKKQSQVQTIEHRLQKQDPQRRLQMYEQSFDE
MQLRLQQAMQTKLHAYALKQQNLSSRLANQSPQHRLTLEAQRLSYLSAKLNDAMDDKLKMSEQRLAHRAQQLDTVSPLAT
LSRGYSITLTGSGKVVQAPSDTCVGDTLTTRLRDGSVTSTVVEVS

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=51.0297482837529, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49140; Mature: 49140

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPKNDVYTVSRLNGEVRQLLEGQLGRIWLNAEISNFAAPGSGHWYLTLKDNFSQIRCA
CCCCCCCCEEHHHCCHHHHHHHCCCCCEEEEEEEHHHCCCCCCCEEEEEECCCHHHHHHH
MFKGRNQAVTFRPANGQQVLVKGNISVYEPRGDYQLLIESMLPAGDGLLAQQYEALKMKL
HHCCCCCEEEEECCCCCEEEEECCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFASDTKRPLPANIQKIGVVTSPTGAAIRDILHVLARRDSSIEVIIYPTPVQGSDA
HHCCCCCCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
AKSICDAINLANSRAEVDVLLVTRGGGSLEDLWSFNDEGLAHTIYNSGIPVVSAVGHEVD
HHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHCCCCCCCEEHHHCCCCCEEECCCCCCC
MTISDYVADLRAPTPSAGAELLSKDADNKAQKLLSQLSRLKQAWQHYQLKKQSQVQTIEH
CCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQKQDPQRRLQMYEQSFDEMQLRLQQAMQTKLHAYALKQQNLSSRLANQSPQHRLTLEA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHH
QRLSYLSAKLNDAMDDKLKMSEQRLAHRAQQLDTVSPLATLSRGYSITLTGSGKVVQAPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCC
DTCVGDTLTTRLRDGSVTSTVVEVS
CCCCCCHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure
MKTPKNDVYTVSRLNGEVRQLLEGQLGRIWLNAEISNFAAPGSGHWYLTLKDNFSQIRCA
CCCCCCCCEEHHHCCHHHHHHHCCCCCEEEEEEEHHHCCCCCCCEEEEEECCCHHHHHHH
MFKGRNQAVTFRPANGQQVLVKGNISVYEPRGDYQLLIESMLPAGDGLLAQQYEALKMKL
HHCCCCCEEEEECCCCCEEEEECCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAEGLFASDTKRPLPANIQKIGVVTSPTGAAIRDILHVLARRDSSIEVIIYPTPVQGSDA
HHCCCCCCCCCCCCCCCHHHEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
AKSICDAINLANSRAEVDVLLVTRGGGSLEDLWSFNDEGLAHTIYNSGIPVVSAVGHEVD
HHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHCCCCCCCEEHHHCCCCCEEECCCCCCC
MTISDYVADLRAPTPSAGAELLSKDADNKAQKLLSQLSRLKQAWQHYQLKKQSQVQTIEH
CCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQKQDPQRRLQMYEQSFDEMQLRLQQAMQTKLHAYALKQQNLSSRLANQSPQHRLTLEA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHH
QRLSYLSAKLNDAMDDKLKMSEQRLAHRAQQLDTVSPLATLSRGYSITLTGSGKVVQAPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCC
DTCVGDTLTTRLRDGSVTSTVVEVS
CCCCCCHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA