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The map label for this gene is intA [H]

Identifier: 157961109

GI number: 157961109

Start: 1564741

End: 1565973

Strand: Reverse

Name: intA [H]

Synonym: Spea_1281

Alternate gene names: 157961109

Gene position: 1565973-1564741 (Counterclockwise)

Preceding gene: 157961110

Following gene: 157961107

Centisome position: 30.26

GC content: 46.39

Gene sequence:

>1233_bases
ATGGCCAATTCCACTAAGCAGCTCACCGCAACACAAGTTTCAAATGCAAAGCCAAAAGAGAAAGAATACAACCTTGCTGA
CGGCAGAGGGTTATCACTCAGAGTCAAAACCGGAGGTTCAAAGTTTTGGTTACTGAACTACACTCGGCCTGTAACTCAAA
AGCGAGCCAACCTAGGTTTAGGTACCTACCCAGATGTACCACTAGCAGAAGCAAGAAAGCGAAGAGAAGCCGCCCGTGAA
CTTCTTGCTCAAGGTATTGACCCTCAACACCACCAGCAGCAACAGAAAGCTGCCATAAAAACCGATGCAGAAAACACCCT
CAAGTCTGTAACCAACGCATGGTTTGAAATTAAAAAGCAGAAGGTCTCAGAAAATCACGGTCAAAAGCTGTATCGTCGAC
TTGAGCTTTACCTGTTTCCAGCCCTTGGTGGAACACCAATCAGTGTCTTAACCGCCCCACAAGTTATTCAAGTACTCAAG
CCTGCAGAAGCTAAAGGCAATATTGAAACCTGCAAGCGCGTGATCAGCTGGCTAAACGAAGTAATGACCTTTGCAGTCAA
TACTGGCCTTATCCACTCGAACCCACTTATTGGCATAGCAGCAGCGTTTGGCGTCCCAGAGAAGCGACAAATGCCAACCC
TCAAACCAGCAGAACTACCAGAGTTTATTGAAGCACTAACCTACTCTAGTATAAAGAAAACAACTCGATGCTTGATCGAG
ATACAACTGCACACTATGACCCGCCCAGCAGAAGCAGCAAAAGCGAAGTGGACTGAAATTGATTTTGATAAGCAGCTGTG
GACGATTCCAGCTGAACGCATGAAGATGAAGCGTGAACATATCATCCCACTCACGCCACAGGTCATATCGCTGCTAAATC
GCATGCATGAAATCAGCGGTGACTTGGAATACATATTCCCAGCAGATAGAAACAAACATCACCACACCAACACCGAAACT
GCCAATATGGCTATTAAGCGTATGGGCTACAAAGGCCGCTTAGTGGCTCATGGGCTACGTGCGTTAGCCAGCACCACATT
AAACGAACAAGGCTTTGATGCTGAACTAATAGAGGTGTCACTAGCTCACGTGGATAAAAACACCGTTCGAGCAGCCTATA
ACCGCGCAGACTACATTGAGCGACGCAGAGAGCTTATGTGCTGGTGGAGTGAGCATGTTCAGATAACTCCAAATCAACTT
AACTCGGTTATTACCCAACAACTCCTCAAGTAA

Upstream 100 bases:

>100_bases
TTAGCGTCTTTTAACGTCTATTGCCATTTCATAGCAGCTTGAGATTAATGTAACACCTAATGTAACATCGGAGCCAAATC
AAGTTCTGGGTGTTACAATC

Downstream 100 bases:

>100_bases
GGATTTAAACTCATATATTCAGCCACCTAAAGCAACTAATAATTTTACGATGATAACTGGTTTTGCTTTTCGATGTAGAG
CCCAAGCAACCCAAAACCTA

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MANSTKQLTATQVSNAKPKEKEYNLADGRGLSLRVKTGGSKFWLLNYTRPVTQKRANLGLGTYPDVPLAEARKRREAARE
LLAQGIDPQHHQQQQKAAIKTDAENTLKSVTNAWFEIKKQKVSENHGQKLYRRLELYLFPALGGTPISVLTAPQVIQVLK
PAEAKGNIETCKRVISWLNEVMTFAVNTGLIHSNPLIGIAAAFGVPEKRQMPTLKPAELPEFIEALTYSSIKKTTRCLIE
IQLHTMTRPAEAAKAKWTEIDFDKQLWTIPAERMKMKREHIIPLTPQVISLLNRMHEISGDLEYIFPADRNKHHHTNTET
ANMAIKRMGYKGRLVAHGLRALASTTLNEQGFDAELIEVSLAHVDKNTVRAAYNRADYIERRRELMCWWSEHVQITPNQL
NSVITQQLLK

Sequences:

>Translated_410_residues
MANSTKQLTATQVSNAKPKEKEYNLADGRGLSLRVKTGGSKFWLLNYTRPVTQKRANLGLGTYPDVPLAEARKRREAARE
LLAQGIDPQHHQQQQKAAIKTDAENTLKSVTNAWFEIKKQKVSENHGQKLYRRLELYLFPALGGTPISVLTAPQVIQVLK
PAEAKGNIETCKRVISWLNEVMTFAVNTGLIHSNPLIGIAAAFGVPEKRQMPTLKPAELPEFIEALTYSSIKKTTRCLIE
IQLHTMTRPAEAAKAKWTEIDFDKQLWTIPAERMKMKREHIIPLTPQVISLLNRMHEISGDLEYIFPADRNKHHHTNTET
ANMAIKRMGYKGRLVAHGLRALASTTLNEQGFDAELIEVSLAHVDKNTVRAAYNRADYIERRRELMCWWSEHVQITPNQL
NSVITQQLLK
>Mature_409_residues
ANSTKQLTATQVSNAKPKEKEYNLADGRGLSLRVKTGGSKFWLLNYTRPVTQKRANLGLGTYPDVPLAEARKRREAAREL
LAQGIDPQHHQQQQKAAIKTDAENTLKSVTNAWFEIKKQKVSENHGQKLYRRLELYLFPALGGTPISVLTAPQVIQVLKP
AEAKGNIETCKRVISWLNEVMTFAVNTGLIHSNPLIGIAAAFGVPEKRQMPTLKPAELPEFIEALTYSSIKKTTRCLIEI
QLHTMTRPAEAAKAKWTEIDFDKQLWTIPAERMKMKREHIIPLTPQVISLLNRMHEISGDLEYIFPADRNKHHHTNTETA
NMAIKRMGYKGRLVAHGLRALASTTLNEQGFDAELIEVSLAHVDKNTVRAAYNRADYIERRRELMCWWSEHVQITPNQLN
SVITQQLLK

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=394, Percent_Identity=45.4314720812183, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788690, Length=385, Percent_Identity=32.4675324675325, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI145693166, Length=390, Percent_Identity=32.5641025641026, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46462; Mature: 46331

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSTKQLTATQVSNAKPKEKEYNLADGRGLSLRVKTGGSKFWLLNYTRPVTQKRANLGL
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHCCCC
GTYPDVPLAEARKRREAARELLAQGIDPQHHQQQQKAAIKTDAENTLKSVTNAWFEIKKQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KVSENHGQKLYRRLELYLFPALGGTPISVLTAPQVIQVLKPAEAKGNIETCKRVISWLNE
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VMTFAVNTGLIHSNPLIGIAAAFGVPEKRQMPTLKPAELPEFIEALTYSSIKKTTRCLIE
HHHHHHHCCEEECCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
IQLHTMTRPAEAAKAKWTEIDFDKQLWTIPAERMKMKREHIIPLTPQVISLLNRMHEISG
EEEHHCCCCHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DLEYIFPADRNKHHHTNTETANMAIKRMGYKGRLVAHGLRALASTTLNEQGFDAELIEVS
CCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LAHVDKNTVRAAYNRADYIERRRELMCWWSEHVQITPNQLNSVITQQLLK
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHC
>Mature Secondary Structure 
ANSTKQLTATQVSNAKPKEKEYNLADGRGLSLRVKTGGSKFWLLNYTRPVTQKRANLGL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHCCCC
GTYPDVPLAEARKRREAARELLAQGIDPQHHQQQQKAAIKTDAENTLKSVTNAWFEIKKQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KVSENHGQKLYRRLELYLFPALGGTPISVLTAPQVIQVLKPAEAKGNIETCKRVISWLNE
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VMTFAVNTGLIHSNPLIGIAAAFGVPEKRQMPTLKPAELPEFIEALTYSSIKKTTRCLIE
HHHHHHHCCEEECCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
IQLHTMTRPAEAAKAKWTEIDFDKQLWTIPAERMKMKREHIIPLTPQVISLLNRMHEISG
EEEHHCCCCHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DLEYIFPADRNKHHHTNTETANMAIKRMGYKGRLVAHGLRALASTTLNEQGFDAELIEVS
CCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
LAHVDKNTVRAAYNRADYIERRRELMCWWSEHVQITPNQLNSVITQQLLK
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]