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The map label for this gene is rsgA2 [H]

Identifier: 157961063

GI number: 157961063

Start: 1504994

End: 1506181

Strand: Reverse

Name: rsgA2 [H]

Synonym: Spea_1235

Alternate gene names: 157961063

Gene position: 1506181-1504994 (Counterclockwise)

Preceding gene: 157961064

Following gene: 157961062

Centisome position: 29.11

GC content: 46.89

Gene sequence:

>1188_bases
ATGACAAAATCAAACCGTTTTAACCACCTAAAATCCAGTACTCTTTCACGTACAACGTCTTCAGCTAGTACCTGCTCATC
GAGTAAATCGTCAGCGGCCAGCTCAACAACGAGTATAGAAATCAATTCTGGCGTATCTACGCCGCTAGAAAATGTCTCTT
TATATAACTTAAAGCAACTTGGCTGGAGTCCGTTTTTTCAGCAACAGCTGATTGAAACTCAAGAGTACGCAAGTGTAGCT
AGAGTGAGTGCTCATCACCGTAGTCAGTATCAATTACTCACAGAAAGCGGCGAATCGACACTTACAATCCATCAAAACAT
GCCAGAAATGACGGTCGGTGACTGGTTACTGTTAGACAGTCAGCAGCAATTTGTTGCTGTACTTGAACGCAGCGCGTTGT
TTAGTCGAAAGGCTGCGGGTTCTAAGGTCGAGCAGCAACTTATCGCAGCGAATCTTGACTGGGTATTTATCGTATCGTCA
CTCAACGATGACTTTAACATTAATCGCATCGAGCGCTACTTGGCACTGGTCCACGAAGCGAAAGTCACACCCGTTATCGT
ACTGACAAAAGTCGATTTATGTGATGATCTTACGCCCTACATAGAAGCGCTAAGAGAGTTGGATGCAAGCTTACTCATCG
AAACCGTTAACGGACTAGATGAGCAAAGCACTCGGGCGCTATCGAGTTATTGCGTTGACGGTAAAACCGTGGCATTTATC
GGCTCTTCAGGTGTGGGGAAATCCACGCTAGTTAACGCTCTATTAGGCGACACCAGTCAGTTAACATCGGCAATTCGCCA
AGACGATAGTAAAGGGCGACATACCACCACTAGCCGTTCACTGCATTTAACTCAAAGCGGCGGGCTATTGCTAGACACAC
CAGGTATGCGCGAGCTACAACTAGCCGATTGCGAAGAGGGACTCAACGAGACCTTTGCCGATCTTGTTGAATACTCGCAG
CAGTGCCGTTTTATCGACTGTCAGCATGAGCAAGAACCCGGCTGCGCCGTACAAGCTGCAATTGAAAATGGCCAGCTAAC
TGAGCGGCGCTTACAAAGCTTTCAAAAGCTGATGCGGGAGCAGGCATTAAATGGCGCCAGTATTGCCGAGAAACGAGCAA
AAGATAAAAACTTAAGCAAGATGTACAAGCGAGTTCAGGGCGAGGCTCGAGTACATAAACGAGGATAA

Upstream 100 bases:

>100_bases
CATAAAGCGCTTTGCCCGGTAGTGAAAACGCTTTACCGGGGTCTTATCTATCAAAAGTCCCCCCAGAATTAATATTCAGG
CGCTTTGCGCTGGGGTTTAT

Downstream 100 bases:

>100_bases
TAGGCCTACTATCTAGAACCTAGAAGCTAGAACCTCATAGGTAATTGCTAATAGCAGGCATACTTAAACATACTTATCTC
AAACATATTTTTTCAAACAT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTKSNRFNHLKSSTLSRTTSSASTCSSSKSSAASSTTSIEINSGVSTPLENVSLYNLKQLGWSPFFQQQLIETQEYASVA
RVSAHHRSQYQLLTESGESTLTIHQNMPEMTVGDWLLLDSQQQFVAVLERSALFSRKAAGSKVEQQLIAANLDWVFIVSS
LNDDFNINRIERYLALVHEAKVTPVIVLTKVDLCDDLTPYIEALRELDASLLIETVNGLDEQSTRALSSYCVDGKTVAFI
GSSGVGKSTLVNALLGDTSQLTSAIRQDDSKGRHTTTSRSLHLTQSGGLLLDTPGMRELQLADCEEGLNETFADLVEYSQ
QCRFIDCQHEQEPGCAVQAAIENGQLTERRLQSFQKLMREQALNGASIAEKRAKDKNLSKMYKRVQGEARVHKRG

Sequences:

>Translated_395_residues
MTKSNRFNHLKSSTLSRTTSSASTCSSSKSSAASSTTSIEINSGVSTPLENVSLYNLKQLGWSPFFQQQLIETQEYASVA
RVSAHHRSQYQLLTESGESTLTIHQNMPEMTVGDWLLLDSQQQFVAVLERSALFSRKAAGSKVEQQLIAANLDWVFIVSS
LNDDFNINRIERYLALVHEAKVTPVIVLTKVDLCDDLTPYIEALRELDASLLIETVNGLDEQSTRALSSYCVDGKTVAFI
GSSGVGKSTLVNALLGDTSQLTSAIRQDDSKGRHTTTSRSLHLTQSGGLLLDTPGMRELQLADCEEGLNETFADLVEYSQ
QCRFIDCQHEQEPGCAVQAAIENGQLTERRLQSFQKLMREQALNGASIAEKRAKDKNLSKMYKRVQGEARVHKRG
>Mature_394_residues
TKSNRFNHLKSSTLSRTTSSASTCSSSKSSAASSTTSIEINSGVSTPLENVSLYNLKQLGWSPFFQQQLIETQEYASVAR
VSAHHRSQYQLLTESGESTLTIHQNMPEMTVGDWLLLDSQQQFVAVLERSALFSRKAAGSKVEQQLIAANLDWVFIVSSL
NDDFNINRIERYLALVHEAKVTPVIVLTKVDLCDDLTPYIEALRELDASLLIETVNGLDEQSTRALSSYCVDGKTVAFIG
SSGVGKSTLVNALLGDTSQLTSAIRQDDSKGRHTTTSRSLHLTQSGGLLLDTPGMRELQLADCEEGLNETFADLVEYSQQ
CRFIDCQHEQEPGCAVQAAIENGQLTERRLQSFQKLMREQALNGASIAEKRAKDKNLSKMYKRVQGEARVHKRG

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover [H]

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain [H]

Homologues:

Organism=Escherichia coli, GI87082381, Length=244, Percent_Identity=33.6065573770492, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010914
- InterPro:   IPR004881 [H]

Pfam domain/function: PF03193 DUF258 [H]

EC number: NA

Molecular weight: Translated: 43617; Mature: 43486

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSNRFNHLKSSTLSRTTSSASTCSSSKSSAASSTTSIEINSGVSTPLENVSLYNLKQL
CCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCHHCCCHHHHHHH
GWSPFFQQQLIETQEYASVARVSAHHRSQYQLLTESGESTLTIHQNMPEMTVGDWLLLDS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECC
QQQFVAVLERSALFSRKAAGSKVEQQLIAANLDWVFIVSSLNDDFNINRIERYLALVHEA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHC
KVTPVIVLTKVDLCDDLTPYIEALRELDASLLIETVNGLDEQSTRALSSYCVDGKTVAFI
CCCEEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEE
GSSGVGKSTLVNALLGDTSQLTSAIRQDDSKGRHTTTSRSLHLTQSGGLLLDTPGMRELQ
CCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEE
LADCEEGLNETFADLVEYSQQCRFIDCQHEQEPGCAVQAAIENGQLTERRLQSFQKLMRE
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
QALNGASIAEKRAKDKNLSKMYKRVQGEARVHKRG
HCCCCHHHHHHHHHCCCHHHHHHHHHCHHHHCCCC
>Mature Secondary Structure 
TKSNRFNHLKSSTLSRTTSSASTCSSSKSSAASSTTSIEINSGVSTPLENVSLYNLKQL
CCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCHHCCCHHHHHHH
GWSPFFQQQLIETQEYASVARVSAHHRSQYQLLTESGESTLTIHQNMPEMTVGDWLLLDS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEECC
QQQFVAVLERSALFSRKAAGSKVEQQLIAANLDWVFIVSSLNDDFNINRIERYLALVHEA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHC
KVTPVIVLTKVDLCDDLTPYIEALRELDASLLIETVNGLDEQSTRALSSYCVDGKTVAFI
CCCEEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEE
GSSGVGKSTLVNALLGDTSQLTSAIRQDDSKGRHTTTSRSLHLTQSGGLLLDTPGMRELQ
CCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEE
LADCEEGLNETFADLVEYSQQCRFIDCQHEQEPGCAVQAAIENGQLTERRLQSFQKLMRE
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
QALNGASIAEKRAKDKNLSKMYKRVQGEARVHKRG
HCCCCHHHHHHHHHCCCHHHHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]