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The map label for this gene is yrkL [H]

Identifier: 157961054

GI number: 157961054

Start: 1491385

End: 1492005

Strand: Reverse

Name: yrkL [H]

Synonym: Spea_1226

Alternate gene names: 157961054

Gene position: 1492005-1491385 (Counterclockwise)

Preceding gene: 157961060

Following gene: 157961053

Centisome position: 28.83

GC content: 47.18

Gene sequence:

>621_bases
ATGGCACTCGCGGCAAAAAAAATCCTCGTATTGTATGCACATCCCTCCCAAGAACGATCTGAAATCAACACTCCCCTGTT
TAAAGCGACCCAATTACAGCCGAACGTGACTGCCATTGATCTCTATGGTGAATACCCCACTTTCAGGATCAATATCGATA
AAGAACAACAAAGACTCAGAGACCACGACATAGTGGTCTTTATGTTTCCGCTGTACTGGTACTCCACTCCAGCCATTTTA
AAAGAGTGGCAAGATCTGGTCTTAGAGTACAACTTTGCCTACGGTACTAAAGGTAAAACCCTATGTGGCAAAACCTTTTT
GTGTGCACTTAGCGCAGGGGGCAGTGAAGCCGCCTACAATGAAGATGGCTACAATCACTTTACCCTAAGAGAGCTACTTC
GCCCCCTTGAGCAGATGGCCAACTTAACCGGTATGAAGTTCTTAGCGCCTTTTGCCCTGTTCTGCGCTCGCAGCGCCTCA
GAGGAAAACCGAGTCGATACCCATGTGCAAAAGTGGGTTCGAACACTCAAGGCACTTAGTGAGGACAGATTCGATATCGA
ACAGGCTCAATCCCTTGAAAAACTCAATGGTCACCTCGACCAATTGATCCGGGAGCACTAA

Upstream 100 bases:

>100_bases
GATGGAAGAGCAAGCCTTCAAATCTCAAAAAAACTTAGCGCATCTTGCTGTCTATGCTAGATTAAATAACAATCTGTTAT
GTCAACTGACTGGATAAAAA

Downstream 100 bases:

>100_bases
TTATGACTGCTTATTTTATTCAAGCTTTTATCTATTTATGCGCCGCCGTCATCGCCGTGCCTATTGCTAAGCGGCTCGGC
CTAGGCTCAGTGCTGGGCTA

Product: NAD(P)H dehydrogenase (quinone)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MALAAKKILVLYAHPSQERSEINTPLFKATQLQPNVTAIDLYGEYPTFRINIDKEQQRLRDHDIVVFMFPLYWYSTPAIL
KEWQDLVLEYNFAYGTKGKTLCGKTFLCALSAGGSEAAYNEDGYNHFTLRELLRPLEQMANLTGMKFLAPFALFCARSAS
EENRVDTHVQKWVRTLKALSEDRFDIEQAQSLEKLNGHLDQLIREH

Sequences:

>Translated_206_residues
MALAAKKILVLYAHPSQERSEINTPLFKATQLQPNVTAIDLYGEYPTFRINIDKEQQRLRDHDIVVFMFPLYWYSTPAIL
KEWQDLVLEYNFAYGTKGKTLCGKTFLCALSAGGSEAAYNEDGYNHFTLRELLRPLEQMANLTGMKFLAPFALFCARSAS
EENRVDTHVQKWVRTLKALSEDRFDIEQAQSLEKLNGHLDQLIREH
>Mature_205_residues
ALAAKKILVLYAHPSQERSEINTPLFKATQLQPNVTAIDLYGEYPTFRINIDKEQQRLRDHDIVVFMFPLYWYSTPAILK
EWQDLVLEYNFAYGTKGKTLCGKTFLCALSAGGSEAAYNEDGYNHFTLRELLRPLEQMANLTGMKFLAPFALFCARSASE
ENRVDTHVQKWVRTLKALSEDRFDIEQAQSLEKLNGHLDQLIREH

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=219, Percent_Identity=31.5068493150685, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1789750, Length=157, Percent_Identity=45.2229299363057, Blast_Score=136, Evalue=8e-34,
Organism=Escherichia coli, GI1786231, Length=156, Percent_Identity=35.2564102564103, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 23735; Mature: 23604

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAAKKILVLYAHPSQERSEINTPLFKATQLQPNVTAIDLYGEYPTFRINIDKEQQRLR
CCCCCCEEEEEEECCCHHHHHCCCCHHHHCCCCCCCEEEEEECCCCEEEEEECHHHHHHH
DHDIVVFMFPLYWYSTPAILKEWQDLVLEYNFAYGTKGKTLCGKTFLCALSAGGSEAAYN
HCCEEEEEEHHHHHCCHHHHHHHHHHHHHHCCEECCCCCCHHHHHHEEEEECCCCCCCCC
EDGYNHFTLRELLRPLEQMANLTGMKFLAPFALFCARSASEENRVDTHVQKWVRTLKALS
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
EDRFDIEQAQSLEKLNGHLDQLIREH
CCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALAAKKILVLYAHPSQERSEINTPLFKATQLQPNVTAIDLYGEYPTFRINIDKEQQRLR
CCCCCEEEEEEECCCHHHHHCCCCHHHHCCCCCCCEEEEEECCCCEEEEEECHHHHHHH
DHDIVVFMFPLYWYSTPAILKEWQDLVLEYNFAYGTKGKTLCGKTFLCALSAGGSEAAYN
HCCEEEEEEHHHHHCCHHHHHHHHHHHHHHCCEECCCCCCHHHHHHEEEEECCCCCCCCC
EDGYNHFTLRELLRPLEQMANLTGMKFLAPFALFCARSASEENRVDTHVQKWVRTLKALS
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
EDRFDIEQAQSLEKLNGHLDQLIREH
CCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]