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The map label for this gene is sigZ [H]

Identifier: 157960330

GI number: 157960330

Start: 614605

End: 615147

Strand: Direct

Name: sigZ [H]

Synonym: Spea_0501

Alternate gene names: 157960330

Gene position: 614605-615147 (Clockwise)

Preceding gene: 157960329

Following gene: 157960331

Centisome position: 11.88

GC content: 42.17

Gene sequence:

>543_bases
ATGAAACTTGAAAATATTTGGTCTGCTTATCGACGTCAATTGGAAGCATTCTTACACTCCAAAGTGTCCAATGCTGCTGA
TGTTGAAGATTTACTGCAGGAGATATTAATTAAAACCCACACTGGCCTTGATAGTCTGCAAAAAGGGGAGAGTATTCAAG
CCTGGTTGTTTCAGATCGCCAATCGAACCACTATTGATTTTTATAGAAAAAAAGCGCGTCTTAAAGAGTTAGATCCAGAA
GAGTTATGGTATCAAGAGAAGCAGCAAGATATTAAGGCAGAGCTAATCCCCTGTATCGAACCGTTTCTAACGGCGCTGCC
TGATGATATGGCATCGTTACTGCGTGCTATCGACTTAGAGGGGAAGTCTCAAAAGGCATACGCGCAGGAGAAAGGGATCA
ACTACACCACCCTTAAATCTAAAGTGCAAAAGAGCCGAGCAACACTAAGGGGGCTGTTTGAGGGGTGTTGTCATTACAGT
TTAGATCCACAGGGTAACCTTATCGACTTTGAACAAAAATCTGCGTCATGCAAAAAATGCTAA

Upstream 100 bases:

>100_bases
ACAACAACGGCTGAAGGTTAATAGAGTGACATTTTAGCCTTTATGCTCTGATGCAGATGGTTATAGTTATATTGTTGTTC
ACTATTTTTCAGAGGTGCTA

Downstream 100 bases:

>100_bases
ATAACTTCGTCCTTTCTATGCCTGCATCGTCTTATAGGTAAATTCATTAACGATATAGGTTTAAAAATGTTGAAAATAGT
AAGTTATGTCATATGTCCAT

Product: RNA polymerase sigma factor SigZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKLENIWSAYRRQLEAFLHSKVSNAADVEDLLQEILIKTHTGLDSLQKGESIQAWLFQIANRTTIDFYRKKARLKELDPE
ELWYQEKQQDIKAELIPCIEPFLTALPDDMASLLRAIDLEGKSQKAYAQEKGINYTTLKSKVQKSRATLRGLFEGCCHYS
LDPQGNLIDFEQKSASCKKC

Sequences:

>Translated_180_residues
MKLENIWSAYRRQLEAFLHSKVSNAADVEDLLQEILIKTHTGLDSLQKGESIQAWLFQIANRTTIDFYRKKARLKELDPE
ELWYQEKQQDIKAELIPCIEPFLTALPDDMASLLRAIDLEGKSQKAYAQEKGINYTTLKSKVQKSRATLRGLFEGCCHYS
LDPQGNLIDFEQKSASCKKC
>Mature_180_residues
MKLENIWSAYRRQLEAFLHSKVSNAADVEDLLQEILIKTHTGLDSLQKGESIQAWLFQIANRTTIDFYRKKARLKELDPE
ELWYQEKQQDIKAELIPCIEPFLTALPDDMASLLRAIDLEGKSQKAYAQEKGINYTTLKSKVQKSRATLRGLFEGCCHYS
LDPQGNLIDFEQKSASCKKC

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014304
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20687; Mature: 20687

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLENIWSAYRRQLEAFLHSKVSNAADVEDLLQEILIKTHTGLDSLQKGESIQAWLFQIA
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
NRTTIDFYRKKARLKELDPEELWYQEKQQDIKAELIPCIEPFLTALPDDMASLLRAIDLE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GKSQKAYAQEKGINYTTLKSKVQKSRATLRGLFEGCCHYSLDPQGNLIDFEQKSASCKKC
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHCCCCCCC
>Mature Secondary Structure
MKLENIWSAYRRQLEAFLHSKVSNAADVEDLLQEILIKTHTGLDSLQKGESIQAWLFQIA
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
NRTTIDFYRKKARLKELDPEELWYQEKQQDIKAELIPCIEPFLTALPDDMASLLRAIDLE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GKSQKAYAQEKGINYTTLKSKVQKSRATLRGLFEGCCHYSLDPQGNLIDFEQKSASCKKC
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]