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The map label for this gene is dmpD [H]

Identifier: 157960147

GI number: 157960147

Start: 356147

End: 357073

Strand: Direct

Name: dmpD [H]

Synonym: Spea_0318

Alternate gene names: 157960147

Gene position: 356147-357073 (Clockwise)

Preceding gene: 157960146

Following gene: 157960148

Centisome position: 6.88

GC content: 50.05

Gene sequence:

>927_bases
ATGACGTTGGAGGTGAACGTGCGCCATATCTCTCTATTGCTAGTGACGCTATTTATGACGGCATGTTCTGCCGTGGATAT
TGTCGATTCTCGCGAGCAGTCAGCACTGCAAAAAGCCGGATTTGAACAGAGTCAGCTCAGCCTGCACGAGGGCGGTGAGC
TTAATTATTGGCAGGCCGGCGAGGGCAAAACAGTATTACTCATCCATGGTTTTGGTGGCACGGCTGTAACTAGTTGGCAG
CAGGTGATGCTTGAACTGAGTCAAGATTATCGCGTTATAGCTCCGGATCTCGCCTGGTTTGGGCAGTCGGTTAGCAATGG
CAAGCCTAGCCTAGCGACTCAATCACAAGCCATTATGCAGCTGATCGATTCCCTTGATTTAGATAAGGTCAATGTGGTCG
GGATCTCTTACGGCGGCTTCGTCACCTTCGATTTGATGATTAACGAACCTAAGGTCGACAAGGCGGTATTGCTGGCGAGC
CCCGGTGTGTTGTTTTCTGATAATGCCTTGCTGCAGATGAATCAGCGTTTTGAGGTCGATGATCCAAGCGACATCTTTGT
ACCTGAGACGCCGAAGCAGATGCGGCGTTTACTCGATGCCACCTTCGTCGATTTTCCTTGGTATCCGGGCTTTATTGACG
CGCGAATCTTCGATAAATACTTCGCAGATTATTTGGATGAAAAGCGACAGCTGATCGAAGGACTTCCCGCTGACAGAGAC
CGGATTGCCGCTAATATCTCGGTCGACTCACTGCCACCGAGCGTGTTGATCTGGGGCGAGAATGATAAAGTTTTCCCACT
GAGTTCAGGTATTCAACTGGCCGATTACTTGACCGCGCCTATTGTGGTTATCCCTCAGGGAGCCCATGGGATCAGTAACG
ACTACCCAGAGATTATCAGTCAGACAATTAGGGCGTTTGTGCAATGA

Upstream 100 bases:

>100_bases
TGGTAGTCAGGTGGGATTGACCAAGAATGTGGATCTGCTGATGGAGTTTGGTGTTGGCACCCGTAGCAGCTTCATGATGA
GCCTAGGTTACCGTTTTTAA

Downstream 100 bases:

>100_bases
TCAGGCGAATATTCAGCCATGGTGCTGTGAGTGTTATCGCTATTTTTATACTTAGCGCTTGTGGTAGCAGCGACTGGCAG
GTGCGCGCCTTGCCCAGTGA

Product: alpha/beta hydrolase fold protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTLEVNVRHISLLLVTLFMTACSAVDIVDSREQSALQKAGFEQSQLSLHEGGELNYWQAGEGKTVLLIHGFGGTAVTSWQ
QVMLELSQDYRVIAPDLAWFGQSVSNGKPSLATQSQAIMQLIDSLDLDKVNVVGISYGGFVTFDLMINEPKVDKAVLLAS
PGVLFSDNALLQMNQRFEVDDPSDIFVPETPKQMRRLLDATFVDFPWYPGFIDARIFDKYFADYLDEKRQLIEGLPADRD
RIAANISVDSLPPSVLIWGENDKVFPLSSGIQLADYLTAPIVVIPQGAHGISNDYPEIISQTIRAFVQ

Sequences:

>Translated_308_residues
MTLEVNVRHISLLLVTLFMTACSAVDIVDSREQSALQKAGFEQSQLSLHEGGELNYWQAGEGKTVLLIHGFGGTAVTSWQ
QVMLELSQDYRVIAPDLAWFGQSVSNGKPSLATQSQAIMQLIDSLDLDKVNVVGISYGGFVTFDLMINEPKVDKAVLLAS
PGVLFSDNALLQMNQRFEVDDPSDIFVPETPKQMRRLLDATFVDFPWYPGFIDARIFDKYFADYLDEKRQLIEGLPADRD
RIAANISVDSLPPSVLIWGENDKVFPLSSGIQLADYLTAPIVVIPQGAHGISNDYPEIISQTIRAFVQ
>Mature_307_residues
TLEVNVRHISLLLVTLFMTACSAVDIVDSREQSALQKAGFEQSQLSLHEGGELNYWQAGEGKTVLLIHGFGGTAVTSWQQ
VMLELSQDYRVIAPDLAWFGQSVSNGKPSLATQSQAIMQLIDSLDLDKVNVVGISYGGFVTFDLMINEPKVDKAVLLASP
GVLFSDNALLQMNQRFEVDDPSDIFVPETPKQMRRLLDATFVDFPWYPGFIDARIFDKYFADYLDEKRQLIEGLPADRDR
IAANISVDSLPPSVLIWGENDKVFPLSSGIQLADYLTAPIVVIPQGAHGISNDYPEIISQTIRAFVQ

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 34115; Mature: 33984

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEVNVRHISLLLVTLFMTACSAVDIVDSREQSALQKAGFEQSQLSLHEGGELNYWQAG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCCCCEEECC
EGKTVLLIHGFGGTAVTSWQQVMLELSQDYRVIAPDLAWFGQSVSNGKPSLATQSQAIMQ
CCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHH
LIDSLDLDKVNVVGISYGGFVTFDLMINEPKVDKAVLLASPGVLFSDNALLQMNQRFEVD
HHHHCCCCCEEEEEEECCCEEEEEEEECCCCCCCEEEEECCCEEECCCCEEEECCCCCCC
DPSDIFVPETPKQMRRLLDATFVDFPWYPGFIDARIFDKYFADYLDEKRQLIEGLPADRD
CCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RIAANISVDSLPPSVLIWGENDKVFPLSSGIQLADYLTAPIVVIPQGAHGISNDYPEIIS
HEEEEEEECCCCCEEEEECCCCEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCHHHHHH
QTIRAFVQ
HHHHHHCC
>Mature Secondary Structure 
TLEVNVRHISLLLVTLFMTACSAVDIVDSREQSALQKAGFEQSQLSLHEGGELNYWQAG
EEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCCCCEEECC
EGKTVLLIHGFGGTAVTSWQQVMLELSQDYRVIAPDLAWFGQSVSNGKPSLATQSQAIMQ
CCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCCCCCCCCHHHHHHHHH
LIDSLDLDKVNVVGISYGGFVTFDLMINEPKVDKAVLLASPGVLFSDNALLQMNQRFEVD
HHHHCCCCCEEEEEEECCCEEEEEEEECCCCCCCEEEEECCCEEECCCCEEEECCCCCCC
DPSDIFVPETPKQMRRLLDATFVDFPWYPGFIDARIFDKYFADYLDEKRQLIEGLPADRD
CCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RIAANISVDSLPPSVLIWGENDKVFPLSSGIQLADYLTAPIVVIPQGAHGISNDYPEIIS
HEEEEEEECCCCCEEEEECCCCEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCHHHHHH
QTIRAFVQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]