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The map label for this gene is rpoB [H]

Identifier: 157960007

GI number: 157960007

Start: 197180

End: 201211

Strand: Direct

Name: rpoB [H]

Synonym: Spea_0177

Alternate gene names: 157960007

Gene position: 197180-201211 (Clockwise)

Preceding gene: 157960006

Following gene: 157960008

Centisome position: 3.81

GC content: 44.72

Gene sequence:

>4032_bases
ATGGTTTACTCCTATTCTGAAAAGAAGCGTATTCGCAAAGACTTTGGTAAACGTCCACGTGTTTTGGATATTCCTTACCT
TTTGTCAATCCAGTTGGACTCTTTTAAGAAGTTCACCGATCAAGATCCTACAGGTGAGCGTGGCTTTGAAGCTGCCTTCC
GTAGCGTTTTTCCCATCAAGAGCTTTTCTGGTAATTCTGAGCTGCAATATGTCAGCTATAAACTAGGCGAGCCTGTTTTT
GATGTGAAAGAGTGTCAAATCCGCGGTGTTACATACTCTGCACCACTACGCGTTAAATTGCGTATGGTACTGTATGACCG
TGAAGCGGCACCTGGCACAGTAAAAGACATCAAAGAACAAGAAGTCTATATGGGGGATATCCCTCTTATGACTGACAACG
GTACCTTTGTTATCAATGGTACTGAGCGTGTAATCGTATCTCAGCTACACCGTAGCCCGGGCGTATTCTTTGATCATGAC
CGTGGTAAAACCCACTCTTCAGGTAAGGTGCTGTATAACGCACGTATTATTCCTTACCGTGGTTCATGGTTAGACTTTGA
ATTCGATCCGAAAGATGCACTGTTTGTTCGTATTGACCGCCGTCGTAAGTTAGCGGCATCGATCATTCTGCGCGCTTTAG
ATTATTCAACTCAAGATATCCTTGACCTGTTCTTCGATCGCGTCAACTTTAAGATCAAGAAAGATTCACTAGTAATGGAT
CTTGTTGCTGACCGCCTACGTGGCGAAACAGCAAGCTATGATATTAAAGACGCTGAAGGCACTGTTCTTGTTGAGAAGGG
TCGTCGCATCACTGCACGTCACATTCGTCAACTTGAAAAGACAAACACAACTGAGCTTGAAGTGCCAGTTGAGTACATCG
CTGGTAAGATTTCTGGACAAGATTATATCGATCCAGATACAGGCGAAGTATTGGTTTCTGCAAACGCAGACATCAGCCTA
GAAGATCTAGCTAAGCTATCAATGGCTGGCATCAAAGAGATCAGCACTCTGTATATCAATGAACTTGATAACGGTGCCTA
CATCTCTGACACACTACGTATTGATTCAACAACTAACCGCCTTGAAGCGCTAGTTGAAATCTACCGTATGATGCGTCCTG
GTGAGCCACCAACCAAAGATGCAGCAGAAGCACTATTCAACAACCTATTCTTCAGCGAAGAACGTTATGACCTTTCAAAA
GTAGGTCGTATGAAGTTCAATCGTCGTCTAAGCATTGATGACGATGAAGGTACTGGTATTCTTTCTAAAGAAGATATCGT
TGCCGTGATGAAGAACATCATCGCAATCCGTAACGGTTTCGACGAAGTGGATGATATCGATCATCTAGGTAACCGTCGTA
TTCGTAGTGTTGGCGAAATGGCTGAAAACCAGTTCCGTGTTGGTCTAGTTCGTGTTGAACGTGCCGTACGTGAGCGTTTA
AGCCTTGGCGATCTAAATGAGCTAATGCCTCAAGATTTGATCAACGCTAAGCCAATCTCTGCAGCTGTTAAAGAATTCTT
TGGCTCTTCACAGCTTTCACAGTTCATGGACCAAAACAACCCATTGTCAGAAGTGACGCATAAGCGTCGTATCTCTGCTC
TAGGTCCTGGTGGTCTAACGCGTGAACGTGCTGGTTTCGAAGTTCGAGACGTACATCCGACTCACTATGGTCGTCTATGT
CCAATCGAAACGCCAGAAGGTCCAAACATTGGTTTGATCAACTCGTTGTCAACCTTTGCTCGTACCAACAACTATGGTTT
CCTTGAAACACCTTACCGTAAGGTTATCGATGGTGTGGTTACTGATGAGGTAGATTACCTTTCAGCAATCGAAGAAGGCC
GTTACGTTATTGCACAGGCTATCGTTCAGTTAGATGAGAACGGTCGCATGATGGACGAGTTAATTGCTTGTCGTCATAAA
GGTGATTCAACCTTTATGGGTGCAGCTGACATCCAGTACATGGACGTTTCACCACAGCAGATTATTTCTGTTGCGGCGTC
ACTAATTCCGTTCCTGGAACACGATGATGCTAACCGTGCATTGATGGGTGCGAACATGCAACGTCAGGCAGTTCCAACAC
TAAAGGCCGATAAGCCATTAGTTGGTACTGGTATTGAGCGTACACTTGCTGTTGACTCAGGCGTGGTAGTTGCTGCTAAA
CGTGGTGGTTATGTTGACTACGTTGATGCGAGCCGTATCGTTGTTAAAGTTAACGAAGCTGAGCTAACTCCAGGCGAAGC
GGGTATCGATATCTACAACTTGACCAAATACACGCGTTCTAACCAGAACACTTGTATTAACCAGCGTCCTTGTTGTTCTG
TTGGTGACCCAATTGTTCGTGGCGACGTTCTTGCTGATGGCCCATCTACCGACTTAGGTGATTTGGCTCTTGGTCAGAAC
ATGCGTATCGCGTTCATGCCTTGGAACGGTTACAACTTCGAAGATTCGATCTTAATCTCTGAGCGTGTAGCTCAGGAAGA
CCGTTTCACAACTATCCACATTCAAGAGCTTTCATGTATCGCTCGTGATACTAAGTTGGGTAGTGAAGAGATCACAGCTG
ATATTCCAAACGTTGGTGAGTCTGCGCTTTCTAAGCTAGATGAATCAGGTATCGTTTATATCGGTGCAGAAGTTAAGGGT
GGTGACATCCTAGTTGGTAAAGTAACACCTAAAGGTGAAACTCAGCTGACTCCAGAAGAGAAACTTCTCCGTGCAATCTT
CGGCGAAAAAGCCTCTGACGTTAAAGACAGCTCACTACGCGTACCTAACTCTGTTAAAGGTACTATCATCGACGTACAAG
TATTTACTCGTGACGGCGTTGAGAAAGACAAGCGTGCTGTAGAAATTGAAGAGATGCATATCGCCCAGGCGAAGAAGGAT
TTGACTGAAGAGTTCCAAATTCTTGAAGATGGTGTTATCGGTCGTGCTCGCAACCTATTAATTGGTGCTGGTTTCGATGA
AGCCCAACTTGCTGCAATTCCACGTTCACAATTGTTGGTTCAAACCATCGATGATGAAGTTAAGCAAACTGAGCTAGAAC
AACTAGCTGAGCAAGCGGAAGAGCTAAAAGCCGATTTCGATAAGAAGTTTGAAATCAAGCGTCGTAAGATCACTCAAGGT
GATGACTTAGCACCTGGCGTACTTAAGATCGTTAAGGTTTACCTAGCGGTTAAGCGTACTATCCAGCCTGGTGATAAGAT
GGCGGGTCGTCATGGTAACAAGGGTGTAATCTCTAAGATTTGTCCTGTTGAAGACATGCCATACGACGAAAAGGGTAACC
CAGTAGATATCGTATTGAATCCACTAGGTGTACCTTCACGTATGAACATCGGTCAGGTACTTGAAGTTCATATGGGTGCT
GCAGCGAAAGGCATCGGTAATCGTATTACTGAGATGCTGGAAGAGCAGCGCGAATTGGCAGAACTTCGCGGATACATCAA
GCAGGTTTATGAACTAGGTGACGAAGTAATTCAAAAAGTCGACATCGATTCATTTACTGATGATGAAATCTTGCGTCTTG
CTAAAAACCTAAAAGGCGGTGTACCGATTGCTACACCTGCGTTTGATGGCGCCAAAGAGAAAGAGATCAAGCAGATGCTT
GAGCTTGCAGGCTTGCCACAATCTGGTCAGTTAACACTGATTGATGGTCGTACTGGTAACGAATTTGAGCGTAAGGTAAC
CGTTGGTTACATGTATATGCTTAAGCTTAACCACTTGGTTGACGACAAGATGCACGCTCGTTCTACGGGTTCGTACAGTC
TTGTTACTCAGCAGCCATTGGGTGGTAAAGCACAGTTCGGTGGTCAGCGTTTCGGTGAGATGGAAGTATGGGCACTTGAA
GCTTACGGTGCAGCATATACCCTTCAGGAAATGCTAACTGTTAAGTCAGATGATGTTAACGGTCGTACTCAGATGTATAA
GAACATCGTCGACGGTAACCATCAGATGCAACCAGGTATGCCTGAATCTTTCAACGTATTGTTGAAAGAGATCCGTTCAC
TTGGTATCAACATTGAGTTAGATACTAAGTAA

Upstream 100 bases:

>100_bases
TACTGGTTAGGTTCTTGCTTTCAACGGTGATGGGCAAACGCGCTGTTTCAACAGTTAAGTTGAATCAGTCTTGGTCACAT
CTCGCAATCAGAGGAAACCC

Downstream 100 bases:

>100_bases
AACAGGTTACCGCCTCTATTTGGCAAAATCGGTGCTCTGCATATGCGGAGCACCTGATTTAACTCCTTCAGGAGAGAAAC
GTGAAAGATTTATTAAAGTT

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1343; Mature: 1343

Protein sequence:

>1343_residues
MVYSYSEKKRIRKDFGKRPRVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
DVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHD
RGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMD
LVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQDYIDPDTGEVLVSANADISL
EDLAKLSMAGIKEISTLYINELDNGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSK
VGRMKFNRRLSIDDDEGTGILSKEDIVAVMKNIIAIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVVTDEVDYLSAIEEGRYVIAQAIVQLDENGRMMDELIACRHK
GDSTFMGAADIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAK
RGGYVDYVDASRIVVKVNEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPIVRGDVLADGPSTDLGDLALGQN
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKD
LTEEFQILEDGVIGRARNLLIGAGFDEAQLAAIPRSQLLVQTIDDEVKQTELEQLAEQAEELKADFDKKFEIKRRKITQG
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGA
AAKGIGNRITEMLEEQRELAELRGYIKQVYELGDEVIQKVDIDSFTDDEILRLAKNLKGGVPIATPAFDGAKEKEIKQML
ELAGLPQSGQLTLIDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDTK

Sequences:

>Translated_1343_residues
MVYSYSEKKRIRKDFGKRPRVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
DVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHD
RGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMD
LVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQDYIDPDTGEVLVSANADISL
EDLAKLSMAGIKEISTLYINELDNGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSK
VGRMKFNRRLSIDDDEGTGILSKEDIVAVMKNIIAIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVVTDEVDYLSAIEEGRYVIAQAIVQLDENGRMMDELIACRHK
GDSTFMGAADIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAK
RGGYVDYVDASRIVVKVNEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPIVRGDVLADGPSTDLGDLALGQN
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKD
LTEEFQILEDGVIGRARNLLIGAGFDEAQLAAIPRSQLLVQTIDDEVKQTELEQLAEQAEELKADFDKKFEIKRRKITQG
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGA
AAKGIGNRITEMLEEQRELAELRGYIKQVYELGDEVIQKVDIDSFTDDEILRLAKNLKGGVPIATPAFDGAKEKEIKQML
ELAGLPQSGQLTLIDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDTK
>Mature_1343_residues
MVYSYSEKKRIRKDFGKRPRVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
DVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHD
RGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMD
LVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQDYIDPDTGEVLVSANADISL
EDLAKLSMAGIKEISTLYINELDNGAYISDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSK
VGRMKFNRRLSIDDDEGTGILSKEDIVAVMKNIIAIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
PIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVVTDEVDYLSAIEEGRYVIAQAIVQLDENGRMMDELIACRHK
GDSTFMGAADIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAK
RGGYVDYVDASRIVVKVNEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPIVRGDVLADGPSTDLGDLALGQN
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKG
GDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKD
LTEEFQILEDGVIGRARNLLIGAGFDEAQLAAIPRSQLLVQTIDDEVKQTELEQLAEQAEELKADFDKKFEIKRRKITQG
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKICPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGA
AAKGIGNRITEMLEEQRELAELRGYIKQVYELGDEVIQKVDIDSFTDDEILRLAKNLKGGVPIATPAFDGAKEKEIKQML
ELAGLPQSGQLTLIDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALE
AYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDTK

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI212286172, Length=260, Percent_Identity=31.9230769230769, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI33469941, Length=260, Percent_Identity=31.9230769230769, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI4505941, Length=304, Percent_Identity=28.6184210526316, Blast_Score=117, Evalue=1e-25,
Organism=Homo sapiens, GI238908503, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI238908505, Length=160, Percent_Identity=34.375, Blast_Score=82, Evalue=3e-15,
Organism=Escherichia coli, GI1790419, Length=1341, Percent_Identity=79.5674869500373, Blast_Score=2226, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=302, Percent_Identity=29.4701986754967, Blast_Score=121, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=234, Percent_Identity=31.1965811965812, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17552304, Length=249, Percent_Identity=30.9236947791165, Blast_Score=114, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=248, Percent_Identity=31.8548387096774, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=252, Percent_Identity=32.1428571428571, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324725, Length=312, Percent_Identity=27.8846153846154, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17647877, Length=297, Percent_Identity=29.2929292929293, Blast_Score=120, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17136446, Length=263, Percent_Identity=32.319391634981, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=30.5220883534137, Blast_Score=110, Evalue=6e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 149717; Mature: 149717

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYSYSEKKRIRKDFGKRPRVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIK
CCCCCHHHHHHHHHHCCCCCEEECCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
SFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQ
CCCCCCCEEEEEEECCCCCCCCCCEEEECEEECCCCEEEEEEEEEECCCCCCHHHHHHHH
EVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
HEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMD
CCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEECCCHHHHH
LVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQ
HHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCC
DYIDPDTGEVLVSANADISLEDLAKLSMAGIKEISTLYINELDNGAYISDTLRIDSTTNR
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEECCHHHH
LEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSKVGRMKFNRRLSIDDDEGTGI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LSKEDIVAVMKNIIAIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLT
CCCCHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
RERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVV
HHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TDEVDYLSAIEEGRYVIAQAIVQLDENGRMMDELIACRHKGDSTFMGAADIQYMDVSPQQ
HCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEECCCCEEEECCCHHH
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAK
HHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCEEEEEC
RGGYVDYVDASRIVVKVNEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPIVR
CCCEEEEECCCEEEEEEECCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCCEE
GDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCI
CCEECCCCCCCCCCHHCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCEEEEEEHHHHHH
ARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
HHHCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKD
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHEEHHHHHHHHHHHH
LTEEFQILEDGVIGRARNLLIGAGFDEAQLAAIPRSQLLVQTIDDEVKQTELEQLAEQAE
HHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKI
HHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHC
CPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGNRITEMLEEQRELA
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
ELRGYIKQVYELGDEVIQKVDIDSFTDDEILRLAKNLKGGVPIATPAFDGAKEKEIKQML
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHH
ELAGLPQSGQLTLIDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPL
HHHCCCCCCCEEEEECCCCCCHHHEEEEHEEEEEHHHHHHCCHHHHCCCCCEEEEECCCC
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGM
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
PESFNVLLKEIRSLGINIELDTK
CHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MVYSYSEKKRIRKDFGKRPRVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIK
CCCCCHHHHHHHHHHCCCCCEEECCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
SFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQ
CCCCCCCEEEEEEECCCCCCCCCCEEEECEEECCCCEEEEEEEEEECCCCCCHHHHHHHH
EVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
HEEECCCEEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEEC
GSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMD
CCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEECCCHHHHH
LVADRLRGETASYDIKDAEGTVLVEKGRRITARHIRQLEKTNTTELEVPVEYIAGKISGQ
HHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCC
DYIDPDTGEVLVSANADISLEDLAKLSMAGIKEISTLYINELDNGAYISDTLRIDSTTNR
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEECCHHHH
LEALVEIYRMMRPGEPPTKDAAEALFNNLFFSEERYDLSKVGRMKFNRRLSIDDDEGTGI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LSKEDIVAVMKNIIAIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLT
CCCCHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
RERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLSTFARTNNYGFLETPYRKVIDGVV
HHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TDEVDYLSAIEEGRYVIAQAIVQLDENGRMMDELIACRHKGDSTFMGAADIQYMDVSPQQ
HCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEECCCCEEEECCCHHH
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAK
HHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCEEEEEC
RGGYVDYVDASRIVVKVNEAELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPIVR
CCCEEEEECCCEEEEEEECCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCCEE
GDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCI
CCEECCCCCCCCCCHHCCCCCEEEEEECCCCCCCCCEEHHHHHCCCCCEEEEEEHHHHHH
ARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
HHHCCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHH
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKD
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHEEHHHHHHHHHHHH
LTEEFQILEDGVIGRARNLLIGAGFDEAQLAAIPRSQLLVQTIDDEVKQTELEQLAEQAE
HHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKI
HHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHC
CPVEDMPYDEKGNPVDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGNRITEMLEEQRELA
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
ELRGYIKQVYELGDEVIQKVDIDSFTDDEILRLAKNLKGGVPIATPAFDGAKEKEIKQML
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHH
ELAGLPQSGQLTLIDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPL
HHHCCCCCCCEEEEECCCCCCHHHEEEEHEEEEEHHHHHHCCHHHHCCCCCEEEEECCCC
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGM
CCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCC
PESFNVLLKEIRSLGINIELDTK
CHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]