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The map label for this gene is nusG [H]

Identifier: 157960002

GI number: 157960002

Start: 193942

End: 194493

Strand: Direct

Name: nusG [H]

Synonym: Spea_0172

Alternate gene names: 157960002

Gene position: 193942-194493 (Clockwise)

Preceding gene: 157960001

Following gene: 157960003

Centisome position: 3.75

GC content: 43.3

Gene sequence:

>552_bases
ATGACTGAAGCTACTGAAGCTAAAAAGAGATGGTATGTTATTCAAGCGTTTTCCGGCTATGAAGGCCGTGTATGTAAAAC
TTTGCTTGAACATATCAGAATGCACGAAATGGAAAACTACTTTGGTGAGGTGCTAGTTCCTACTGAAGAAGTGGTTGAAA
TGCGTGCAGGCCAACGTCGTAAGAGCGAACGTAAATTTTTCCCTGGCTATGTACTAGTACAGATGGAAATGAATGATGAA
AGCTGGCACTTGGTTAAGAGTATTCCACGTGTAATGGGCTTCATCGGTGGTACGTCTGATCGTCCTGCCCCTATTTCTGA
TAAAGAAGCTGATGCAATTCTTCAGCGTCTTCAAGAAACTACAGAGTCTCCAACGCACCGCGTTATGTTTGAGCCTGGTG
AAGTTGTTCGTGTTAATGACGGACCTTTTGCCGACTTCAACGGTACTGTTGAAGAAGTGGATTATGAGAAGAACCGCGTT
AAGGTTTCTGTGATGATCTTCGGTCGCTCGACTCCTGTTGAACTTGATTTTAGTCAGATTGAAAAAAGCTGA

Upstream 100 bases:

>100_bases
TGTATTAGCTGCAACAGCCGTTTTAGGTTTAATCCTTTGGGGCTTAGACGCAGTATTGCTTAGAATTGTTAATTTTATTA
CAGGCGTATAGGCATTAAGT

Downstream 100 bases:

>100_bases
TTAAATAAAGCGCAAATTTTATTTGAAATGGGTGTGAATTTATATATAATTCGCACCCATATTTTTCGGGGAGCTGTTCA
GCATAGTGCTGATAGCGTTT

Product: NusG antitermination factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTEATEAKKRWYVIQAFSGYEGRVCKTLLEHIRMHEMENYFGEVLVPTEEVVEMRAGQRRKSERKFFPGYVLVQMEMNDE
SWHLVKSIPRVMGFIGGTSDRPAPISDKEADAILQRLQETTESPTHRVMFEPGEVVRVNDGPFADFNGTVEEVDYEKNRV
KVSVMIFGRSTPVELDFSQIEKS

Sequences:

>Translated_183_residues
MTEATEAKKRWYVIQAFSGYEGRVCKTLLEHIRMHEMENYFGEVLVPTEEVVEMRAGQRRKSERKFFPGYVLVQMEMNDE
SWHLVKSIPRVMGFIGGTSDRPAPISDKEADAILQRLQETTESPTHRVMFEPGEVVRVNDGPFADFNGTVEEVDYEKNRV
KVSVMIFGRSTPVELDFSQIEKS
>Mature_182_residues
TEATEAKKRWYVIQAFSGYEGRVCKTLLEHIRMHEMENYFGEVLVPTEEVVEMRAGQRRKSERKFFPGYVLVQMEMNDES
WHLVKSIPRVMGFIGGTSDRPAPISDKEADAILQRLQETTESPTHRVMFEPGEVVRVNDGPFADFNGTVEEVDYEKNRVK
VSVMIFGRSTPVELDFSQIEKS

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=183, Percent_Identity=76.5027322404372, Blast_Score=299, Evalue=6e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 21098; Mature: 20967

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEATEAKKRWYVIQAFSGYEGRVCKTLLEHIRMHEMENYFGEVLVPTEEVVEMRAGQRR
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHCCHH
KSERKFFPGYVLVQMEMNDESWHLVKSIPRVMGFIGGTSDRPAPISDKEADAILQRLQET
HHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TESPTHRVMFEPGEVVRVNDGPFADFNGTVEEVDYEKNRVKVSVMIFGRSTPVELDFSQI
HCCCCEEEEECCCCEEEECCCCCCCCCCCHHHCCCCCCEEEEEEEEEECCCCCEECHHHH
EKS
CCC
>Mature Secondary Structure 
TEATEAKKRWYVIQAFSGYEGRVCKTLLEHIRMHEMENYFGEVLVPTEEVVEMRAGQRR
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHCCHH
KSERKFFPGYVLVQMEMNDESWHLVKSIPRVMGFIGGTSDRPAPISDKEADAILQRLQET
HHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TESPTHRVMFEPGEVVRVNDGPFADFNGTVEEVDYEKNRVKVSVMIFGRSTPVELDFSQI
HCCCCEEEEECCCCEEEECCCCCCCCCCCHHHCCCCCCEEEEEEEEEECCCCCEECHHHH
EKS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]