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The map label for this gene is ptrB [H]

Identifier: 157959962

GI number: 157959962

Start: 146933

End: 149083

Strand: Direct

Name: ptrB [H]

Synonym: Spea_0132

Alternate gene names: 157959962

Gene position: 146933-149083 (Clockwise)

Preceding gene: 157959959

Following gene: 157959963

Centisome position: 2.84

GC content: 47.75

Gene sequence:

>2151_bases
ATGAAATTGTTTGCTCCGCTCATACTCAGCGCTGTATTGCTATTTGGATGTAATAATATGACCACCACCCAAGCTGTAAA
ACCACCGCAAGCCGATAAAGTTCCACATAGCATGACACTCCATGGGGTGACCCGTGTCGACGATTATTACTGGATGCGGG
ATGACGAGCGCAAAGAAGACAAGGTGATTGCGCATTTAAACGCTGAAAATGCCTATGCCAAACAAGAGTTCAAGGCTTTT
GGCGACCTAAAGCAAGGTTTGTTTGATGAGCTGGTGGGCCGTTTAGATAAGGACGAGTCGAGTGTGCCTTATTTCTGGCA
TCGGCATTGGTATTACCGTTATTACAAACAGGGCTTTGAATACCCAGTTATTGCCCGTAAAACCGCGTTAGAGAGTGACC
AAGAACAAGTACTGCTAGATGTGAACGAACGCGCGGAAGGCAAAGACTTCTATGGTTTGGGCGGCGTGTCGGTAAGCCCA
GATGAAACCAAGCTAGTGTTCGGTGAAGATCTTCTTAGCCGACGTATTTATACCTTGTACTTTAAAGATCTCACAAGCGG
CGAGCTAATGGGTGACAAGCTTGAAGGGACGGATGGTGGCGTTGTATGGTCTAACGATAATCAGCATCTGTTCTATATCG
CCAAAGATCCGCAAACCCTGCTCGGTTATCAAGTATTCCGTCATAAGTTAGGCACGGCGCAATCTGAAGACGTACTAGTG
TATGAAGAGCAAGACGACGCCTTCTATATCAGTTTAGGTAAATCGCTGGATGAGTCGGTTATTGTCTTGCATGCCGAAAG
CACAGTGACTAGCGAAGTTAGCATGCTGGATGCGAATCAATCTTTGGCTAAGTTTGAGCCTGTCTTAGCAAGGGAAGAGG
GGCATGAGTATTCGGTGTCTAAGTTGGGCGACAGCTATTACATATTAACCAACTGGCAGGCGACTAACTTCCGCCTGATG
AAGGTAGCAATTAGTCAGGCGGCAGATAAGAGCGCTTGGCAAGATGTGATAGCCCATGACCAAAATTCACGCATAGAAGA
TGTATTGCTGCTGAGTGACTATATGGTGGTGCAAACTCGTGAGCGAGGCATTAGTCGTATTCGAGTGTATCCGTTTAATG
AGCAGGTTGAGTTTGAGCTGGCCTTTAACGATCCCGCCTATGTAGTGGGTTTCGATATTAACCCAAGCCAGCAAAGCGAT
AAGCTAAGGATTTATTACTCAAGCCCAACTACGCCTGAGTCTGTGTATGAATATGCACTGGCTAAGCCGAATCAGCGTGA
GTTACTTAAACAAGAGCAAGTGCTTGGTGATTTTAATGCCGATGATTATCAGGCGGAACGTTTGTTTATTGAGGCTCGTG
ATGGTAAAGAGGTGCCAGTGACCTTGGTCTATCGCAAAGATAAGTTCAATAAGGATGGCACGAATCCGCTTTATCAATAT
GGCTACGGCTCCTATGGCTATACCGTCGAGCCAGACTTTAGCTCATCGGCATTGAGCTTACTGGATCGCGGTGTGGTGTA
CGCCATTGCCCATGTGCGAGGTTCTGAGATGCTCGGTCGTGGCTGGTATGACGACGGACGAATGCTCAATAAGCAGAACA
GCTTTAACGATTTCGTCGATGTAACTAAAGCATTGACTGAGCAAGGTTACGGCGCAAAAGATAAGGTGGTTGCCGCTGGT
GGCAGTGCCGGTGGCTTGTTAATGGGCGGCGTAATCAATCAGGCGCCAGAGCGTTACTTTGCCGTGGCAGCTCATGTGCC
GTTTGTCGATGTGGTCACCACCATGCTCGATGAGTCGATCCCACTTACCACTAACGAGTATGACGAGTGGGGTAACCCCA
ACGAGAAGGTCTATTTCGACTATATGCTCAGCTACGCACCTTATGACAACGTCAGTGCCCAAGCTTATCCGCATCTGCTA
GTGACCACCGGCTTACATGACTCACAAGTACAGTACTTTGAGCCAGCTAAGTGGGTGGCTAAGCTGCGTGATGTGAAGAC
TGACAGCAATATGCTGTTGTTTGATACCGATATGGAAGCGGGGCACGGTGGCAAGAGTGGCCGCTATCGCCAATATGAGG
ATACCGCTAAAGAGTATGCCTTCTTCTTAGGTTTGCTAGGGTTAGATACTGCTAAGAATACTAGTCGCTAA

Upstream 100 bases:

>100_bases
AAAATGGCGCGATAGTGCAAAAAACTGTCGATACCGCGATTCATGATCGCCCCAGTCAATTTACGGAATATTTTGACTGA
AAATTATAAAGGGATGTTAG

Downstream 100 bases:

>100_bases
TGCATAACTCCGTAGAGACAGTTATCGAGCCGGCAAAGGTGCAAGACCCAGCAAGCGACATCAAAGTGAGTAAAGCTAAA
GTTATTGAAACCAAGGCAAG

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MKLFAPLILSAVLLFGCNNMTTTQAVKPPQADKVPHSMTLHGVTRVDDYYWMRDDERKEDKVIAHLNAENAYAKQEFKAF
GDLKQGLFDELVGRLDKDESSVPYFWHRHWYYRYYKQGFEYPVIARKTALESDQEQVLLDVNERAEGKDFYGLGGVSVSP
DETKLVFGEDLLSRRIYTLYFKDLTSGELMGDKLEGTDGGVVWSNDNQHLFYIAKDPQTLLGYQVFRHKLGTAQSEDVLV
YEEQDDAFYISLGKSLDESVIVLHAESTVTSEVSMLDANQSLAKFEPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLM
KVAISQAADKSAWQDVIAHDQNSRIEDVLLLSDYMVVQTRERGISRIRVYPFNEQVEFELAFNDPAYVVGFDINPSQQSD
KLRIYYSSPTTPESVYEYALAKPNQRELLKQEQVLGDFNADDYQAERLFIEARDGKEVPVTLVYRKDKFNKDGTNPLYQY
GYGSYGYTVEPDFSSSALSLLDRGVVYAIAHVRGSEMLGRGWYDDGRMLNKQNSFNDFVDVTKALTEQGYGAKDKVVAAG
GSAGGLLMGGVINQAPERYFAVAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKVYFDYMLSYAPYDNVSAQAYPHLL
VTTGLHDSQVQYFEPAKWVAKLRDVKTDSNMLLFDTDMEAGHGGKSGRYRQYEDTAKEYAFFLGLLGLDTAKNTSR

Sequences:

>Translated_716_residues
MKLFAPLILSAVLLFGCNNMTTTQAVKPPQADKVPHSMTLHGVTRVDDYYWMRDDERKEDKVIAHLNAENAYAKQEFKAF
GDLKQGLFDELVGRLDKDESSVPYFWHRHWYYRYYKQGFEYPVIARKTALESDQEQVLLDVNERAEGKDFYGLGGVSVSP
DETKLVFGEDLLSRRIYTLYFKDLTSGELMGDKLEGTDGGVVWSNDNQHLFYIAKDPQTLLGYQVFRHKLGTAQSEDVLV
YEEQDDAFYISLGKSLDESVIVLHAESTVTSEVSMLDANQSLAKFEPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLM
KVAISQAADKSAWQDVIAHDQNSRIEDVLLLSDYMVVQTRERGISRIRVYPFNEQVEFELAFNDPAYVVGFDINPSQQSD
KLRIYYSSPTTPESVYEYALAKPNQRELLKQEQVLGDFNADDYQAERLFIEARDGKEVPVTLVYRKDKFNKDGTNPLYQY
GYGSYGYTVEPDFSSSALSLLDRGVVYAIAHVRGSEMLGRGWYDDGRMLNKQNSFNDFVDVTKALTEQGYGAKDKVVAAG
GSAGGLLMGGVINQAPERYFAVAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKVYFDYMLSYAPYDNVSAQAYPHLL
VTTGLHDSQVQYFEPAKWVAKLRDVKTDSNMLLFDTDMEAGHGGKSGRYRQYEDTAKEYAFFLGLLGLDTAKNTSR
>Mature_716_residues
MKLFAPLILSAVLLFGCNNMTTTQAVKPPQADKVPHSMTLHGVTRVDDYYWMRDDERKEDKVIAHLNAENAYAKQEFKAF
GDLKQGLFDELVGRLDKDESSVPYFWHRHWYYRYYKQGFEYPVIARKTALESDQEQVLLDVNERAEGKDFYGLGGVSVSP
DETKLVFGEDLLSRRIYTLYFKDLTSGELMGDKLEGTDGGVVWSNDNQHLFYIAKDPQTLLGYQVFRHKLGTAQSEDVLV
YEEQDDAFYISLGKSLDESVIVLHAESTVTSEVSMLDANQSLAKFEPVLAREEGHEYSVSKLGDSYYILTNWQATNFRLM
KVAISQAADKSAWQDVIAHDQNSRIEDVLLLSDYMVVQTRERGISRIRVYPFNEQVEFELAFNDPAYVVGFDINPSQQSD
KLRIYYSSPTTPESVYEYALAKPNQRELLKQEQVLGDFNADDYQAERLFIEARDGKEVPVTLVYRKDKFNKDGTNPLYQY
GYGSYGYTVEPDFSSSALSLLDRGVVYAIAHVRGSEMLGRGWYDDGRMLNKQNSFNDFVDVTKALTEQGYGAKDKVVAAG
GSAGGLLMGGVINQAPERYFAVAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPNEKVYFDYMLSYAPYDNVSAQAYPHLL
VTTGLHDSQVQYFEPAKWVAKLRDVKTDSNMLLFDTDMEAGHGGKSGRYRQYEDTAKEYAFFLGLLGLDTAKNTSR

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=703, Percent_Identity=24.75106685633, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI284172438, Length=565, Percent_Identity=26.3716814159292, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172431, Length=565, Percent_Identity=26.3716814159292, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172420, Length=565, Percent_Identity=26.3716814159292, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172413, Length=565, Percent_Identity=26.3716814159292, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI70778815, Length=565, Percent_Identity=26.3716814159292, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI108860686, Length=562, Percent_Identity=24.5551601423488, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI108860692, Length=213, Percent_Identity=35.2112676056338, Blast_Score=127, Evalue=4e-29,
Organism=Escherichia coli, GI1788150, Length=679, Percent_Identity=47.8645066273932, Blast_Score=655, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=718, Percent_Identity=24.9303621169916, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI221510989, Length=713, Percent_Identity=25.1051893408135, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 81266; Mature: 81266

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFAPLILSAVLLFGCNNMTTTQAVKPPQADKVPHSMTLHGVTRVDDYYWMRDDERKED
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCEEECCCCCCCCC
KVIAHLNAENAYAKQEFKAFGDLKQGLFDELVGRLDKDESSVPYFWHRHWYYRYYKQGFE
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCC
YPVIARKTALESDQEQVLLDVNERAEGKDFYGLGGVSVSPDETKLVFGEDLLSRRIYTLY
CCEEEHHHHCCCCCCEEEEEECCCCCCCCEEECCCEECCCCCCEEEECHHHHHCCEEEEE
FKDLTSGELMGDKLEGTDGGVVWSNDNQHLFYIAKDPQTLLGYQVFRHKLGTAQSEDVLV
EECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEE
YEEQDDAFYISLGKSLDESVIVLHAESTVTSEVSMLDANQSLAKFEPVLAREEGHEYSVS
EECCCCEEEEEECCCCCCCEEEEEECCCCCHHHHEECCCCHHHHHCHHHHHCCCCEEEHH
KLGDSYYILTNWQATNFRLMKVAISQAADKSAWQDVIAHDQNSRIEDVLLLSDYMVVQTR
HCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCEEEEEEH
ERGISRIRVYPFNEQVEFELAFNDPAYVVGFDINPSQQSDKLRIYYSSPTTPESVYEYAL
HCCCCEEEEEECCCCEEEEEEECCCEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHH
AKPNQRELLKQEQVLGDFNADDYQAERLFIEARDGKEVPVTLVYRKDKFNKDGTNPLYQY
CCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHC
GYGSYGYTVEPDFSSSALSLLDRGVVYAIAHVRGSEMLGRGWYDDGRMLNKQNSFNDFVD
CCCCCCCEECCCCCHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCEECCCCCHHHHHH
VTKALTEQGYGAKDKVVAAGGSAGGLLMGGVINQAPERYFAVAAHVPFVDVVTTMLDESI
HHHHHHHCCCCCCCCEEEECCCCCCEEECHHHHHCCHHEEEEEECCCHHHHHHHHHCCCC
PLTTNEYDEWGNPNEKVYFDYMLSYAPYDNVSAQAYPHLLVTTGLHDSQVQYFEPAKWVA
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
KLRDVKTDSNMLLFDTDMEAGHGGKSGRYRQYEDTAKEYAFFLGLLGLDTAKNTSR
HHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLFAPLILSAVLLFGCNNMTTTQAVKPPQADKVPHSMTLHGVTRVDDYYWMRDDERKED
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCEEECCCEEECCCCCCCCC
KVIAHLNAENAYAKQEFKAFGDLKQGLFDELVGRLDKDESSVPYFWHRHWYYRYYKQGFE
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCC
YPVIARKTALESDQEQVLLDVNERAEGKDFYGLGGVSVSPDETKLVFGEDLLSRRIYTLY
CCEEEHHHHCCCCCCEEEEEECCCCCCCCEEECCCEECCCCCCEEEECHHHHHCCEEEEE
FKDLTSGELMGDKLEGTDGGVVWSNDNQHLFYIAKDPQTLLGYQVFRHKLGTAQSEDVLV
EECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEE
YEEQDDAFYISLGKSLDESVIVLHAESTVTSEVSMLDANQSLAKFEPVLAREEGHEYSVS
EECCCCEEEEEECCCCCCCEEEEEECCCCCHHHHEECCCCHHHHHCHHHHHCCCCEEEHH
KLGDSYYILTNWQATNFRLMKVAISQAADKSAWQDVIAHDQNSRIEDVLLLSDYMVVQTR
HCCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCEEEEEEH
ERGISRIRVYPFNEQVEFELAFNDPAYVVGFDINPSQQSDKLRIYYSSPTTPESVYEYAL
HCCCCEEEEEECCCCEEEEEEECCCEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHH
AKPNQRELLKQEQVLGDFNADDYQAERLFIEARDGKEVPVTLVYRKDKFNKDGTNPLYQY
CCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHC
GYGSYGYTVEPDFSSSALSLLDRGVVYAIAHVRGSEMLGRGWYDDGRMLNKQNSFNDFVD
CCCCCCCEECCCCCHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCCEECCCCCHHHHHH
VTKALTEQGYGAKDKVVAAGGSAGGLLMGGVINQAPERYFAVAAHVPFVDVVTTMLDESI
HHHHHHHCCCCCCCCEEEECCCCCCEEECHHHHHCCHHEEEEEECCCHHHHHHHHHCCCC
PLTTNEYDEWGNPNEKVYFDYMLSYAPYDNVSAQAYPHLLVTTGLHDSQVQYFEPAKWVA
CCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
KLRDVKTDSNMLLFDTDMEAGHGGKSGRYRQYEDTAKEYAFFLGLLGLDTAKNTSR
HHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]