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The map label for this gene is glpG [H]

Identifier: 157959934

GI number: 157959934

Start: 117717

End: 118556

Strand: Reverse

Name: glpG [H]

Synonym: Spea_0104

Alternate gene names: 157959934

Gene position: 118556-117717 (Counterclockwise)

Preceding gene: 157959935

Following gene: 157959932

Centisome position: 2.29

GC content: 47.02

Gene sequence:

>840_bases
ATGATTGAGATTGGCAGACTTCCTAACAACCGAGCAGCACAGGCTCTCATTGACTACCTCAAAGGGCTAAATATTGATTG
TGAGTTAGTGCCGACCGAACAAGGCGTGGCACTGATGATCCATGATCAAAACCACTTAGATCGTGCCCAGCGCGAATTCC
AAGCCTTTATTCATAATCCCTACGACGAAAAGTATCTCGCAGCGTCATGGGAGAATGGCGATACTCGCACCACACTCGAT
TATGGCAGCCCGAGTCTGCAACTGGTCAGTCAGTTTATTACCGGTGCGGGACCTTTAACCTTGCTGGTCTTCTTTACCTG
CGTCGTCATCTACGCTGCGATGAATCTTGGCTTTGCTAACCCTATCTTCGAACAGTTGTCTTTTTTTGGTGCCACCTCCC
CAGCCACACTGAGTGAATTCTGGCGGATTTTTACCCCGAGTTTGCTACACTTTTCTGCCATGCACATCATCTTTAACTTA
CTCTGGTGGTGGTATCTAGGCGGTAAGATTGAAAACAAACTCGGCTTTACCCCACTATTTATTCTATTAATCGTTGGCGG
TACGCTACCTAATATCTTGCAATACTACATGGCAGGGCCTGGCTTTGGCGGTCTGTCTGGCGTGGTCTATGCTGTTGTCG
GTTACACATGGATTATGGGCGTAAAACGGCCCGAATCAGGCATAGGTCTGCCTCCAGCTTATATTGGCTTTATGTTGTTA
TGGCTGGTCTTTGGCTTTACCGATATGTTTGGCCTCTCTATTGCCAACGGTGCCCACTTAGGTGGTTTATTGGTAGGGTT
GATTCAAGGGTTTGTTGATAGTAAGACTCGTAAGATTTAA

Upstream 100 bases:

>100_bases
CTTATCTTAATGAGCAAGGCTTTGATGACGTGTTTAGTTTAGATGGCGGCTATAGCGCGTGGCATCAAGCTAACTTATAA
ACATGTAAGAGGGGGAGAAA

Downstream 100 bases:

>100_bases
ATCTCCTGAATCAATATCGATAGCGGTATTTTCCCCTCGTGATAGCTAGGTTTGCTAGACCCACAATCGTTAGCCCGCAA
ACAGCGGGCGAACGCTTATA

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MIEIGRLPNNRAAQALIDYLKGLNIDCELVPTEQGVALMIHDQNHLDRAQREFQAFIHNPYDEKYLAASWENGDTRTTLD
YGSPSLQLVSQFITGAGPLTLLVFFTCVVIYAAMNLGFANPIFEQLSFFGATSPATLSEFWRIFTPSLLHFSAMHIIFNL
LWWWYLGGKIENKLGFTPLFILLIVGGTLPNILQYYMAGPGFGGLSGVVYAVVGYTWIMGVKRPESGIGLPPAYIGFMLL
WLVFGFTDMFGLSIANGAHLGGLLVGLIQGFVDSKTRKI

Sequences:

>Translated_279_residues
MIEIGRLPNNRAAQALIDYLKGLNIDCELVPTEQGVALMIHDQNHLDRAQREFQAFIHNPYDEKYLAASWENGDTRTTLD
YGSPSLQLVSQFITGAGPLTLLVFFTCVVIYAAMNLGFANPIFEQLSFFGATSPATLSEFWRIFTPSLLHFSAMHIIFNL
LWWWYLGGKIENKLGFTPLFILLIVGGTLPNILQYYMAGPGFGGLSGVVYAVVGYTWIMGVKRPESGIGLPPAYIGFMLL
WLVFGFTDMFGLSIANGAHLGGLLVGLIQGFVDSKTRKI
>Mature_279_residues
MIEIGRLPNNRAAQALIDYLKGLNIDCELVPTEQGVALMIHDQNHLDRAQREFQAFIHNPYDEKYLAASWENGDTRTTLD
YGSPSLQLVSQFITGAGPLTLLVFFTCVVIYAAMNLGFANPIFEQLSFFGATSPATLSEFWRIFTPSLLHFSAMHIIFNL
LWWWYLGGKIENKLGFTPLFILLIVGGTLPNILQYYMAGPGFGGLSGVVYAVVGYTWIMGVKRPESGIGLPPAYIGFMLL
WLVFGFTDMFGLSIANGAHLGGLLVGLIQGFVDSKTRKI

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=281, Percent_Identity=40.9252669039146, Blast_Score=215, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30885; Mature: 30885

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIGRLPNNRAAQALIDYLKGLNIDCELVPTEQGVALMIHDQNHLDRAQREFQAFIHNP
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCC
YDEKYLAASWENGDTRTTLDYGSPSLQLVSQFITGAGPLTLLVFFTCVVIYAAMNLGFAN
CCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
PIFEQLSFFGATSPATLSEFWRIFTPSLLHFSAMHIIFNLLWWWYLGGKIENKLGFTPLF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
ILLIVGGTLPNILQYYMAGPGFGGLSGVVYAVVGYTWIMGVKRPESGIGLPPAYIGFMLL
HHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
WLVFGFTDMFGLSIANGAHLGGLLVGLIQGFVDSKTRKI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEIGRLPNNRAAQALIDYLKGLNIDCELVPTEQGVALMIHDQNHLDRAQREFQAFIHNP
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCC
YDEKYLAASWENGDTRTTLDYGSPSLQLVSQFITGAGPLTLLVFFTCVVIYAAMNLGFAN
CCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
PIFEQLSFFGATSPATLSEFWRIFTPSLLHFSAMHIIFNLLWWWYLGGKIENKLGFTPLF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
ILLIVGGTLPNILQYYMAGPGFGGLSGVVYAVVGYTWIMGVKRPESGIGLPPAYIGFMLL
HHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
WLVFGFTDMFGLSIANGAHLGGLLVGLIQGFVDSKTRKI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA