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The map label for this gene is rpoD [H]

Identifier: 157826344

GI number: 157826344

Start: 1196228

End: 1198135

Strand: Reverse

Name: rpoD [H]

Synonym: A1C_06665

Alternate gene names: 157826344

Gene position: 1198135-1196228 (Counterclockwise)

Preceding gene: 157826345

Following gene: 157826343

Centisome position: 97.33

GC content: 33.33

Gene sequence:

>1908_bases
ATGAGCAATAGCAATATAGACAATGATCTAGATCAAATAGATAGTTTACTTAAAAAAGCTAAATCTAAAAAGATACCTGT
CACTTATGATGATATAAACAAAGCTCTTCCTCTTAATGAAAATCCTTCAATAAGACAATTAGAAGAAGCTATATTAAAAT
TTTCCGATGCGGGAGTAGATATTTTAGAATCTAACGAAGATGATGATATTAAGCTTGATATCGGAATGGATGAAGAATTT
AAGCTATCTACCAATATTGATAATGAACCTGAAGATGAAGCAGAAGAAGAAAATATAGGTACTACCGATGATCCTGTAAG
ATTATATCTTAAGGATATGGGAGGAGTCGATCTTTTAACTCGTGAACACGAAGTAGAAATCGCAAAAAGGATTGAGGAAG
GACGCAAAACAATGACTGCTTCCTTATGCAGAAGCCCTATTGCTATGCGTTGTTTTATAGTATGGTATGAAGATTTAGTT
AATGAAAAAATGTTACTACGTGACCTGATAGATTTAGAAGCTAACATTTTACATGACGAAACACCCGAAAATGATGAAGA
ACATAGTAGTGAGACCGAAGGAGAAGAGCATGATGATAATCACCTATCTATGTCTAGAGTAGAAACGCAGATATTACCTA
ATATCATAGAGCGTATGAAAAAGATTTCTTTTATCTGCGAAGAGCTACTCATTGAAGCTAAAAAATGTTATGAAAAATCT
TTTGAACCTAAAGTTTTACAAAATAGCAAAAAATATAATAATAATTTGGAATTATTATTACATGAAGTTTCGGAAATACA
TTTTAATTCTAAAAGAACGGAAGAAATTTTAGGTAAGATGTATGGAATAAATCGTGATTTAATTAATAAAGAAACAGCTT
TTTTAAAACTTGCTGAAAAATATGGAGTAACGCGCCAAAATTTCCTCGATGAATATATAGGATCGGTTATCAATGCAGCA
TGGAAAGAAAAAATGCTGAAAAATAAAAAAGTCGCTTGGAAAGAGTTAATTACTAAAGAATCGGATTATATAGATCAAAT
GATTGCTGAATTATCGGTTATAGAATCTAATACCGGTCTTTTAGTTAATGATTTTAAAAAACTAGTGAATACTATACAAA
AAAGTGAGAGACAAACACTGCAAGCAAAAAAGGATATGATAGAAGCGAATTTACGTTTAGTTATATCTATCGCTAAAAAA
TATGCTAATAGAGGGTTGCAGTTTTTAGATTTAATTCAAGAGGGTAATATAGGACTTATGAAAGCGGTGGATAAATTTGA
ATATCGCCGTGGTTATAAATTCTCTACCTATGCTACTTGGTGGATTAGACAGGCTATAACAAGAGCTATTGCAGATCAAG
CAAGGACTATACGTATTCCTGTGCATATGATTGAAACAATTAATAAGATACTGCGTACTTCAAGACAAATGCTTAATGAA
CTTGGATACGAACCAACGGCAACGGAAATCGCTAATCGTCTTTCAATGCCGCTTGATAAAGTGCGTAAAGTTATGAAAAT
AGCTAAAGAACCTATAAGTCTTGAGAATCCAGTAGGTGATGATAGTGACGGCGGTCAATTAGGCGATTTTATCGAAGATA
AGAATGCAATAGCACCGATTGATGCAGCGATTCAGTCAAATTTACGAGAAGTTACCACTAGAGTACTTGCAACCCTTACG
CCTCGTGAAGAAAGAGTGCTTAGAATGCGTTTCGGTATAGGTATGAATACTGACCATACATTAGAAGAAGTAGGGCAGCA
ATTTAAGGTAACTAGAGAACGTATAAGACAAATCGAGTCAAAAGCTTTAAGAAAGTTACAACATCCTATTAGATCCAAAA
AACTTAATAGCTTTAGAAGCGGTGGAAAGCGTGGTGAAGGTAATCCATCAGATTTACTAGAGGCATGA

Upstream 100 bases:

>100_bases
ATTGCAAATGAACTTCAAGTTTTAAACGAATCTTTTATTAATCACACGATAAATTAATTATTTCAAACTTCTTGTAAAAG
AAAAAGCATATAGGTATTTA

Downstream 100 bases:

>100_bases
TAATACTTGTATGTCATCCTGTGGTTTTTTGCATGGATACCAAATCGTCATTGCGAGGAGCGAACCGACGTGGCAATCCA
GAAAAATAATAAAATAATTC

Product: RNA polymerase sigma factor RpoD

Products: NA

Alternate protein names: Sigma-70 [H]

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSNSNIDNDLDQIDSLLKKAKSKKIPVTYDDINKALPLNENPSIRQLEEAILKFSDAGVDILESNEDDDIKLDIGMDEEF
KLSTNIDNEPEDEAEEENIGTTDDPVRLYLKDMGGVDLLTREHEVEIAKRIEEGRKTMTASLCRSPIAMRCFIVWYEDLV
NEKMLLRDLIDLEANILHDETPENDEEHSSETEGEEHDDNHLSMSRVETQILPNIIERMKKISFICEELLIEAKKCYEKS
FEPKVLQNSKKYNNNLELLLHEVSEIHFNSKRTEEILGKMYGINRDLINKETAFLKLAEKYGVTRQNFLDEYIGSVINAA
WKEKMLKNKKVAWKELITKESDYIDQMIAELSVIESNTGLLVNDFKKLVNTIQKSERQTLQAKKDMIEANLRLVISIAKK
YANRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKILRTSRQMLNE
LGYEPTATEIANRLSMPLDKVRKVMKIAKEPISLENPVGDDSDGGQLGDFIEDKNAIAPIDAAIQSNLREVTTRVLATLT
PREERVLRMRFGIGMNTDHTLEEVGQQFKVTRERIRQIESKALRKLQHPIRSKKLNSFRSGGKRGEGNPSDLLEA

Sequences:

>Translated_635_residues
MSNSNIDNDLDQIDSLLKKAKSKKIPVTYDDINKALPLNENPSIRQLEEAILKFSDAGVDILESNEDDDIKLDIGMDEEF
KLSTNIDNEPEDEAEEENIGTTDDPVRLYLKDMGGVDLLTREHEVEIAKRIEEGRKTMTASLCRSPIAMRCFIVWYEDLV
NEKMLLRDLIDLEANILHDETPENDEEHSSETEGEEHDDNHLSMSRVETQILPNIIERMKKISFICEELLIEAKKCYEKS
FEPKVLQNSKKYNNNLELLLHEVSEIHFNSKRTEEILGKMYGINRDLINKETAFLKLAEKYGVTRQNFLDEYIGSVINAA
WKEKMLKNKKVAWKELITKESDYIDQMIAELSVIESNTGLLVNDFKKLVNTIQKSERQTLQAKKDMIEANLRLVISIAKK
YANRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKILRTSRQMLNE
LGYEPTATEIANRLSMPLDKVRKVMKIAKEPISLENPVGDDSDGGQLGDFIEDKNAIAPIDAAIQSNLREVTTRVLATLT
PREERVLRMRFGIGMNTDHTLEEVGQQFKVTRERIRQIESKALRKLQHPIRSKKLNSFRSGGKRGEGNPSDLLEA
>Mature_634_residues
SNSNIDNDLDQIDSLLKKAKSKKIPVTYDDINKALPLNENPSIRQLEEAILKFSDAGVDILESNEDDDIKLDIGMDEEFK
LSTNIDNEPEDEAEEENIGTTDDPVRLYLKDMGGVDLLTREHEVEIAKRIEEGRKTMTASLCRSPIAMRCFIVWYEDLVN
EKMLLRDLIDLEANILHDETPENDEEHSSETEGEEHDDNHLSMSRVETQILPNIIERMKKISFICEELLIEAKKCYEKSF
EPKVLQNSKKYNNNLELLLHEVSEIHFNSKRTEEILGKMYGINRDLINKETAFLKLAEKYGVTRQNFLDEYIGSVINAAW
KEKMLKNKKVAWKELITKESDYIDQMIAELSVIESNTGLLVNDFKKLVNTIQKSERQTLQAKKDMIEANLRLVISIAKKY
ANRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKILRTSRQMLNEL
GYEPTATEIANRLSMPLDKVRKVMKIAKEPISLENPVGDDSDGGQLGDFIEDKNAIAPIDAAIQSNLREVTTRVLATLTP
REERVLRMRFGIGMNTDHTLEEVGQQFKVTRERIRQIESKALRKLQHPIRSKKLNSFRSGGKRGEGNPSDLLEA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=625, Percent_Identity=43.84, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1789098, Length=244, Percent_Identity=42.2131147540984, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1789871, Length=249, Percent_Identity=27.710843373494, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788231, Length=199, Percent_Identity=27.1356783919598, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR007631
- InterPro:   IPR007127
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR012760
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04546 Sigma70_ner; PF03979 Sigma70_r1_1; PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 72976; Mature: 72845

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2 ; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSNIDNDLDQIDSLLKKAKSKKIPVTYDDINKALPLNENPSIRQLEEAILKFSDAGVD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCC
ILESNEDDDIKLDIGMDEEFKLSTNIDNEPEDEAEEENIGTTDDPVRLYLKDMGGVDLLT
CCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCCHHHH
REHEVEIAKRIEEGRKTMTASLCRSPIAMRCFIVWYEDLVNEKMLLRDLIDLEANILHDE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPENDEEHSSETEGEEHDDNHLSMSRVETQILPNIIERMKKISFICEELLIEAKKCYEKS
CCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FEPKVLQNSKKYNNNLELLLHEVSEIHFNSKRTEEILGKMYGINRDLINKETAFLKLAEK
CCCHHHHCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YGVTRQNFLDEYIGSVINAAWKEKMLKNKKVAWKELITKESDYIDQMIAELSVIESNTGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
LVNDFKKLVNTIQKSERQTLQAKKDMIEANLRLVISIAKKYANRGLQFLDLIQEGNIGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
KAVDKFEYRRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKILRTSRQMLNE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
LGYEPTATEIANRLSMPLDKVRKVMKIAKEPISLENPVGDDSDGGQLGDFIEDKNAIAPI
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHH
DAAIQSNLREVTTRVLATLTPREERVLRMRFGIGMNTDHTLEEVGQQFKVTRERIRQIES
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KALRKLQHPIRSKKLNSFRSGGKRGEGNPSDLLEA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
SNSNIDNDLDQIDSLLKKAKSKKIPVTYDDINKALPLNENPSIRQLEEAILKFSDAGVD
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCC
ILESNEDDDIKLDIGMDEEFKLSTNIDNEPEDEAEEENIGTTDDPVRLYLKDMGGVDLLT
CCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHCCCCHHHH
REHEVEIAKRIEEGRKTMTASLCRSPIAMRCFIVWYEDLVNEKMLLRDLIDLEANILHDE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPENDEEHSSETEGEEHDDNHLSMSRVETQILPNIIERMKKISFICEELLIEAKKCYEKS
CCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FEPKVLQNSKKYNNNLELLLHEVSEIHFNSKRTEEILGKMYGINRDLINKETAFLKLAEK
CCCHHHHCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YGVTRQNFLDEYIGSVINAAWKEKMLKNKKVAWKELITKESDYIDQMIAELSVIESNTGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
LVNDFKKLVNTIQKSERQTLQAKKDMIEANLRLVISIAKKYANRGLQFLDLIQEGNIGLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHH
KAVDKFEYRRGYKFSTYATWWIRQAITRAIADQARTIRIPVHMIETINKILRTSRQMLNE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
LGYEPTATEIANRLSMPLDKVRKVMKIAKEPISLENPVGDDSDGGQLGDFIEDKNAIAPI
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHH
DAAIQSNLREVTTRVLATLTPREERVLRMRFGIGMNTDHTLEEVGQQFKVTRERIRQIES
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KALRKLQHPIRSKKLNSFRSGGKRGEGNPSDLLEA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA