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The map label for this gene is obgE

Identifier: 157826318

GI number: 157826318

Start: 1171732

End: 1172724

Strand: Reverse

Name: obgE

Synonym: A1C_06535

Alternate gene names: 157826318

Gene position: 1172724-1171732 (Counterclockwise)

Preceding gene: 157826319

Following gene: 157826312

Centisome position: 95.26

GC content: 37.76

Gene sequence:

>993_bases
ATGAATTTTATTGATGAAGTTAAAATATATATAAAAGGCGGGAACGGCGGTAATGGTTGCGTTAGTTTCCATCGTGAGAA
ATTTATTGACAGAGGCGGACCGGACGGTGGGGACGGTGGGCGTGGCGGTAGTGTTATATTTAGGAGTAATCACCATCTTA
ATACGCTAGTAAATTATCGATATAAACAGCATTTTACCGCAGAAAACGGCGAAAATGGTAAAGGTTCAAATAGAAGCGGC
AAATCAGGAAAATCATTAGTTCTTGATGTTCCCATCGGTACTCAAATCTTTTCCGAGGACGGCAATATATTATTGCATGA
CTTCACTGAAGATGACCAAAGCTTTGAAATAATTAAAGGAGGAAGCGGTGGTCTTGGTAACAGCCATTTCAAAACGTCGG
TTAATCAAGCTCCGAGGAAGCGTACGGAAGGGGAAATTGCCGAAGAAATGTGGATTCATTTAAGCTTAAAGCTTCTCTCT
GATGTTGGGCTTGTGGGTCTCCCAAATGCCGGTAAATCTACTTTTTTATCGGTTGTAACGGCCGCCAAGCCTAAAATTGC
CGATTATCCTTTTACTACTTTAGTGCCGCATCTTGGAGTGGTGTATGTTGATGACGAAGAGTTCGTAATAGCTGATATTC
CAGGTTTGATTGAAGGAGCTCATCAAGGACACGGACTTGGCGATAAATTCTTAAAGCATATAGAAAGATGTAATGTATTA
ATACATTTAATAGACGGCTCTAGTAATGATGTAGTGGTAGATTATAACACGGTACGTCTTGAACTTGGGTCATATTCCGA
CCATCTAGAACATAAAATCGAAATCATATGTCTTAATAAATGTGATGTTCTTACCGATGAGGAAATACAAGAAAAAATAA
ATAAGTTACAACAAGCTACTAATAAAGAAGTTTTTTCTATCTCTACATACACTAATCTAGGGGTAAATAAAATAGTTAAA
CTAGCTTTAAAGATTATAAAAAATCAGGAGTAA

Upstream 100 bases:

>100_bases
TTTTACTGGATTGATTCGTCAATTGCTATGCAATGGCCTCGCAATGACAGAAAACCGGCTCCACGCACTCCTTTGCAATG
ACGTTGAAAATATAAATCAT

Downstream 100 bases:

>100_bases
TATATTGCCGGAGCTAAGAAAGACGTGCATTGCCCGCGTGGATACCGATGTCATTCCTGCAAAAGCATGAATCCAAAAAA
AAGTATAAGTACAGCAAATT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKGSNRSG
KSGKSLVLDVPIGTQIFSEDGNILLHDFTEDDQSFEIIKGGSGGLGNSHFKTSVNQAPRKRTEGEIAEEMWIHLSLKLLS
DVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPHLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
IHLIDGSSNDVVVDYNTVRLELGSYSDHLEHKIEIICLNKCDVLTDEEIQEKINKLQQATNKEVFSISTYTNLGVNKIVK
LALKIIKNQE

Sequences:

>Translated_330_residues
MNFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKGSNRSG
KSGKSLVLDVPIGTQIFSEDGNILLHDFTEDDQSFEIIKGGSGGLGNSHFKTSVNQAPRKRTEGEIAEEMWIHLSLKLLS
DVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPHLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
IHLIDGSSNDVVVDYNTVRLELGSYSDHLEHKIEIICLNKCDVLTDEEIQEKINKLQQATNKEVFSISTYTNLGVNKIVK
LALKIIKNQE
>Mature_330_residues
MNFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYRYKQHFTAENGENGKGSNRSG
KSGKSLVLDVPIGTQIFSEDGNILLHDFTEDDQSFEIIKGGSGGLGNSHFKTSVNQAPRKRTEGEIAEEMWIHLSLKLLS
DVGLVGLPNAGKSTFLSVVTAAKPKIADYPFTTLVPHLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
IHLIDGSSNDVVVDYNTVRLELGSYSDHLEHKIEIICLNKCDVLTDEEIQEKINKLQQATNKEVFSISTYTNLGVNKIVK
LALKIIKNQE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=327, Percent_Identity=38.2262996941896, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI111955139, Length=307, Percent_Identity=36.8078175895765, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI111955063, Length=205, Percent_Identity=38.5365853658537, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI58761500, Length=106, Percent_Identity=38.6792452830189, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4557537, Length=92, Percent_Identity=38.0434782608696, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1789574, Length=324, Percent_Identity=48.7654320987654, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1787454, Length=110, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=39.8753894080997, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=30.5194805194805, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=108, Percent_Identity=37.037037037037, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71981008, Length=91, Percent_Identity=35.1648351648352, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=184, Percent_Identity=39.6739130434783, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=87, Percent_Identity=39.0804597701149, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=91, Percent_Identity=35.1648351648352, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129375, Length=316, Percent_Identity=41.4556962025316, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24585318, Length=305, Percent_Identity=33.1147540983607, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24640873, Length=99, Percent_Identity=38.3838383838384, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640877, Length=99, Percent_Identity=38.3838383838384, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640875, Length=99, Percent_Identity=38.3838383838384, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356473, Length=92, Percent_Identity=34.7826086956522, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_RICAH (A8GQ55)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001494038.1
- ProteinModelPortal:   A8GQ55
- SMR:   A8GQ55
- STRING:   A8GQ55
- GeneID:   5645860
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_06535
- NMPDR:   fig|293614.3.peg.1236
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   RAKA293614:A1C_06535-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36182; Mature: 36182

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYR
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
YKQHFTAENGENGKGSNRSGKSGKSLVLDVPIGTQIFSEDGNILLHDFTEDDQSFEIIKG
HHEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCCEEEEEC
GSGGLGNSHFKTSVNQAPRKRTEGEIAEEMWIHLSLKLLSDVGLVGLPNAGKSTFLSVVT
CCCCCCCCHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPHLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
HCCCCCCCCCHHHHHHCCCEEEECCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCEEE
IHLIDGSSNDVVVDYNTVRLELGSYSDHLEHKIEIICLNKCDVLTDEEIQEKINKLQQAT
EEEEECCCCCEEEEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHC
NKEVFSISTYTNLGVNKIVKLALKIIKNQE
CCCEEEEECCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNFIDEVKIYIKGGNGGNGCVSFHREKFIDRGGPDGGDGGRGGSVIFRSNHHLNTLVNYR
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
YKQHFTAENGENGKGSNRSGKSGKSLVLDVPIGTQIFSEDGNILLHDFTEDDQSFEIIKG
HHEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCCEEEEEC
GSGGLGNSHFKTSVNQAPRKRTEGEIAEEMWIHLSLKLLSDVGLVGLPNAGKSTFLSVVT
CCCCCCCCHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPHLGVVYVDDEEFVIADIPGLIEGAHQGHGLGDKFLKHIERCNVL
HCCCCCCCCCHHHHHHCCCEEEECCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCEEE
IHLIDGSSNDVVVDYNTVRLELGSYSDHLEHKIEIICLNKCDVLTDEEIQEKINKLQQAT
EEEEECCCCCEEEEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHC
NKEVFSISTYTNLGVNKIVKLALKIIKNQE
CCCEEEEECCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA