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The map label for this gene is tig [H]

Identifier: 157826317

GI number: 157826317

Start: 1170181

End: 1171518

Strand: Direct

Name: tig [H]

Synonym: A1C_06530

Alternate gene names: 157826317

Gene position: 1170181-1171518 (Clockwise)

Preceding gene: 157826316

Following gene: 157826322

Centisome position: 95.05

GC content: 31.54

Gene sequence:

>1338_bases
ATGGGAATTACCGTATTAAAAAATGAAGGATTGGATTTTCATGCAAGAATCTCTACTCCTTTAAGTGAGATAGATGACGA
TATTCAAAAAGAATTACTTGATTTAACCAAAAAAGTTAAGATAGCAGGTTTTAGAGCTGGTAAAGTACCGGTTTCAATTG
TTAAGCAAAAATACGGTACTTCCGTCAGGAATGATGTAATAGAAAGAAGAATTAACCATTCGGTAAATCACGTTATTAAA
AAACATAATCTAAGTATAATCGGTAGACCAAAAATTGAAGCATTGCAAAACGAACCCGATAAAGCTTTAGCATTTACCGT
AAAAATAGAGCTATTACCTAAAGTTACTATTCCAGATTTAAAGAAAATCTCACTGGATCGTCCAAAATTAGAAGTAAATG
CTAAAGATGTTGAAGAACAACTAGAAAAACTTGCCGCATTAACAAAAAGCTATACTAAAGAAAGTAAAGCAAAAATAAAA
GATGGAGATCAGGTGACTATTGATGCAATCGGGTACATCAAGGACGAAGCTTTTGAAGGCGGTCAATTAAATGATTTAAA
GGTAGTAATAGGTAGTAATGCACTTATTCCAAGTTTTGAGAAGCAATTAATAGGTTCTAAAACAGGTAGTGAAGTAGATG
TTAATGTTACTTTTCCTGAAAATTACCATTCTAAAGATTTAGCAGGTAAAGAGGCTCGTTTTGCAGTACAAATTAAAGCA
GTACATACTGCAGAACCTACCGTTATTGATGATGAGTTTGCTAAAAAATTCCAAAGTAATAGCCTTGAAGAATTGCGTAC
ACATTTTGCTAAACAAATAGAAAACGAATCGGAAGAAGCTATTAATACTATAATGAAAATGAACTTATTTGATCAGTTAG
AAAAATTGTTAGATTTTGACGTACCGGCATCTTTATTAGAGCAAGAAAAAAATATTCTAAAGTCCGAAACCGATAAAAAT
AACCAAGATGAATCATTATTAAAAGATAAATCCCCTAAAGAAATAACAGAATATTATAATAAAGTAGCCCTACGCCGTGT
GCGAATAGGCTTATTACTTGCTGAATACGCAAAATCTAAAAATTTGCAATTAGAGCCTGATGATTTAAGAAAAGTTATTA
TGCAACGAGCACGTAATTTTCCTGGGCAAGAAAATATGATATTTGATTTTTATAAAAATAATCCTAGCGCCATTGAAGGG
CTTAAAGGTCCTGCCTTAGAAGATAAAGCTGTACAATATATATTTAATAACGAAATAAAGCTTAAAGAAAAGAAATATAC
TAAGGAAGAGCTAGAGAAATATCTAGAAGCAGAAGAACAACGTATTACCTTGATTTGA

Upstream 100 bases:

>100_bases
ATTCCTAATCCTCATGGGATTTTACAAAAGCTATTGCATATTTCGGCTCATTAGTTTATTTTGATTAGCAGACTATGCAC
AGAATTAATGGATTATTAAA

Downstream 100 bases:

>100_bases
AGTTTATTAGTTGTCATTGTGAGCAGTTCGTAGCACTTGCGTGAACCAAAAAACTACTCGATACATTCCCGCATATGTGG
GAATCTAGCATAAAGCGAGC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKQKYGTSVRNDVIERRINHSVNHVIK
KHNLSIIGRPKIEALQNEPDKALAFTVKIELLPKVTIPDLKKISLDRPKLEVNAKDVEEQLEKLAALTKSYTKESKAKIK
DGDQVTIDAIGYIKDEAFEGGQLNDLKVVIGSNALIPSFEKQLIGSKTGSEVDVNVTFPENYHSKDLAGKEARFAVQIKA
VHTAEPTVIDDEFAKKFQSNSLEELRTHFAKQIENESEEAINTIMKMNLFDQLEKLLDFDVPASLLEQEKNILKSETDKN
NQDESLLKDKSPKEITEYYNKVALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQRARNFPGQENMIFDFYKNNPSAIEG
LKGPALEDKAVQYIFNNEIKLKEKKYTKEELEKYLEAEEQRITLI

Sequences:

>Translated_445_residues
MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKQKYGTSVRNDVIERRINHSVNHVIK
KHNLSIIGRPKIEALQNEPDKALAFTVKIELLPKVTIPDLKKISLDRPKLEVNAKDVEEQLEKLAALTKSYTKESKAKIK
DGDQVTIDAIGYIKDEAFEGGQLNDLKVVIGSNALIPSFEKQLIGSKTGSEVDVNVTFPENYHSKDLAGKEARFAVQIKA
VHTAEPTVIDDEFAKKFQSNSLEELRTHFAKQIENESEEAINTIMKMNLFDQLEKLLDFDVPASLLEQEKNILKSETDKN
NQDESLLKDKSPKEITEYYNKVALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQRARNFPGQENMIFDFYKNNPSAIEG
LKGPALEDKAVQYIFNNEIKLKEKKYTKEELEKYLEAEEQRITLI
>Mature_444_residues
GITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKQKYGTSVRNDVIERRINHSVNHVIKK
HNLSIIGRPKIEALQNEPDKALAFTVKIELLPKVTIPDLKKISLDRPKLEVNAKDVEEQLEKLAALTKSYTKESKAKIKD
GDQVTIDAIGYIKDEAFEGGQLNDLKVVIGSNALIPSFEKQLIGSKTGSEVDVNVTFPENYHSKDLAGKEARFAVQIKAV
HTAEPTVIDDEFAKKFQSNSLEELRTHFAKQIENESEEAINTIMKMNLFDQLEKLLDFDVPASLLEQEKNILKSETDKNN
QDESLLKDKSPKEITEYYNKVALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQRARNFPGQENMIFDFYKNNPSAIEGL
KGPALEDKAVQYIFNNEIKLKEKKYTKEELEKYLEAEEQRITLI

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=436, Percent_Identity=32.1100917431193, Blast_Score=220, Evalue=1e-58,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 50589; Mature: 50457

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKQKYGT
CCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHCC
SVRNDVIERRINHSVNHVIKKHNLSIIGRPKIEALQNEPDKALAFTVKIELLPKVTIPDL
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCEEEEEEEEEEECCCCCCCC
KKISLDRPKLEVNAKDVEEQLEKLAALTKSYTKESKAKIKDGDQVTIDAIGYIKDEAFEG
HHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHCCCC
GQLNDLKVVIGSNALIPSFEKQLIGSKTGSEVDVNVTFPENYHSKDLAGKEARFAVQIKA
CCCCCEEEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEE
VHTAEPTVIDDEFAKKFQSNSLEELRTHFAKQIENESEEAINTIMKMNLFDQLEKLLDFD
EECCCCCEECHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
VPASLLEQEKNILKSETDKNNQDESLLKDKSPKEITEYYNKVALRRVRIGLLLAEYAKSK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NLQLEPDDLRKVIMQRARNFPGQENMIFDFYKNNPSAIEGLKGPALEDKAVQYIFNNEIK
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCCCCCCCHHHHHHHHCCCEE
LKEKKYTKEELEKYLEAEEQRITLI
EHHHHCCHHHHHHHHHHHHCEEECC
>Mature Secondary Structure 
GITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKQKYGT
CEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHCC
SVRNDVIERRINHSVNHVIKKHNLSIIGRPKIEALQNEPDKALAFTVKIELLPKVTIPDL
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCEEEEEEEEEEECCCCCCCC
KKISLDRPKLEVNAKDVEEQLEKLAALTKSYTKESKAKIKDGDQVTIDAIGYIKDEAFEG
HHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHCCCC
GQLNDLKVVIGSNALIPSFEKQLIGSKTGSEVDVNVTFPENYHSKDLAGKEARFAVQIKA
CCCCCEEEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEE
VHTAEPTVIDDEFAKKFQSNSLEELRTHFAKQIENESEEAINTIMKMNLFDQLEKLLDFD
EECCCCCEECHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
VPASLLEQEKNILKSETDKNNQDESLLKDKSPKEITEYYNKVALRRVRIGLLLAEYAKSK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NLQLEPDDLRKVIMQRARNFPGQENMIFDFYKNNPSAIEGLKGPALEDKAVQYIFNNEIK
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCCCCCCCHHHHHHHHCCCEE
LKEKKYTKEELEKYLEAEEQRITLI
EHHHHCCHHHHHHHHHHHHCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA