| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is kefB [H]
Identifier: 157826270
GI number: 157826270
Start: 1126654
End: 1128381
Strand: Reverse
Name: kefB [H]
Synonym: A1C_06275
Alternate gene names: 157826270
Gene position: 1128381-1126654 (Counterclockwise)
Preceding gene: 157826271
Following gene: 157826269
Centisome position: 91.66
GC content: 35.88
Gene sequence:
>1728_bases ATGAACGATCATATTCTTATTAACGTTATAATTTTACTCGGTACTGCGGTTTTTATTGTGGCTATACTTAAGCGTCTTAG ATTAAGTCCGGTACTTGGTTACTTAATTGCAGGAGCTGCAATAGGTGATCACGGTTTAAAAATCGTAACATATGACCAAA CTAAGTTACTAGGTGAACTTGGTGTAGTATTTCTATTATTTGCGATAGGACTGGAGTTATCTTTTGAGCGATTAAAAGCT ATGAGACGATATGTATTTGGTCTTGGTAGTTTGCAAGTTGTAACAACCGCTATAGTAATTGCCGGTGCAATGGTGCTTAT AGACGGCAATAGTAGTGCAGCTATTATTACCGGCGGTGGTTTGGCCCTTTCATCTACTGCACTTGTTATGCAGGTTATTG AGGAAAATCGTAGTCAATCGACACAAATAGGAAGAATCTCTTTGGCTATTCTGCTACTGCAAGATTTGGCTGTAGTGCCA TTGCTTGTGATAGTTCCGTTACTTGCCGGTAATAATAAAGCCTCGCTTGCAGGGGCTCTTGGTATTGCACTCTTAAAAGC AGTAACGGCCCTACTTACAATATTTATTGTTGGTCGTGTTTTTCTTCGTCCTGTATTTTCATTCATTTCATCAGAAAGTA ATAATACAAGCGAGTTACCTATTTCGATGACTTTGTTAATAGTACTTTCTGCTGCTTGGGCTACCGAAACATTTGGTTTA TCTTTAGCCTTAGGAGCATTTGTTGCTGGAGTATTAGTTGCCGAAACTGAATTTAGATTGCAGGCAGAAGAAAGTATTTA TCCTTTCAAAAGTTTATTTTTAGGATTGTTTTTCATGACTGTCGGTATGAATATCGACGCACTAGAAATGTATGAAAAAA TATCTCATATTCTTACTTTATCTATTGCTTTAATAGGTATAAAAACCTTAATCATAACGGCGTTTTGTCTTTTATTCGGT TTTAATAAAGGAGTTGCTTTTTATTCAGGCTTATTATTATCGCAAGGTGGAGAGTTTGGTTTTATATTATTCAGTTTAGG TAAAGATAGTGGAGTATTAGAAGAAAGTACTGCCGATATATTATTACTCGTAGTTACTTTTACTATGGCACTTACTCCAT TACTCGCGGCTTTAGGGAAAAAGATTGCTGAGAAAGTTGATAAAGGACTCGGTAAAACTCCGACTCAAATGATTGAGCTT GGGGCAAGAGATTTAACAAACCATATTATTATTGCCGGCCTTGGTAATACCGGTAAAATGGTAGCAAGAGTTTTGGAAGC GGAAGGTATAAGTTACGTAATACTTGATTTAGATGATGATAGAGTCAAAGAAGAGCTATCAAACGGTTTGCCGGTTTTTA AAGGTGATGTATCGCAAGCCGATACTCTAAAGGCATTAGGTACGGAAAGAGCATTCGCTATAATACTTACCATGAATAAT CAAGTCACTATAAAGAAATCGCTTAAAACAATTAGCGGTAATTATCAGGATATACCGGTTGTCGTTAAGTTAAAAAATTT AAAAAATGCTAGAGAGTTTTATGATTTAGGTGCCACAACTATTATTCCGGAAAGTTATGAGGCCGGATTACAAATCGGTG GAACAGTCCTGAAGAATATAGGTATTAGCGAGCAGGAAATTAATAGAATAAAAGTACAATTTAGGCTTGGTAATTATATA ATAGCAAAAAAAGAAGATGCTTTATCTGAAGTGGAAGATAATGATTAA
Upstream 100 bases:
>100_bases GTAAATCAGAGTGGGTACTAATAGATGCAGGTACTGTTTTAATTAATATTTTTTATCCTGAAGCACGGGAGCATTTTAAG CTAGAAGAAATTTGGAAAAG
Downstream 100 bases:
>100_bases AGTTTTTATCATTTTAATTACAATAATATTATCTACAACAATTAACGCCGATAATAAAAAATTGTCTATTCCGAGATTTG TTTCAATAAAATCTAATGAA
Product: glutathione-regulated potassium-efflux system protein kefB
Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]
Alternate protein names: K(+)/H(+) antiporter; NEM-activatable K(+)/H(+) antiporter [H]
Number of amino acids: Translated: 575; Mature: 575
Protein sequence:
>575_residues MNDHILINVIILLGTAVFIVAILKRLRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGELGVVFLLFAIGLELSFERLKA MRRYVFGLGSLQVVTTAIVIAGAMVLIDGNSSAAIITGGGLALSSTALVMQVIEENRSQSTQIGRISLAILLLQDLAVVP LLVIVPLLAGNNKASLAGALGIALLKAVTALLTIFIVGRVFLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGL SLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTLSIALIGIKTLIITAFCLLFG FNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADILLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIEL GARDLTNHIIIAGLGNTGKMVARVLEAEGISYVILDLDDDRVKEELSNGLPVFKGDVSQADTLKALGTERAFAIILTMNN QVTIKKSLKTISGNYQDIPVVVKLKNLKNAREFYDLGATTIIPESYEAGLQIGGTVLKNIGISEQEINRIKVQFRLGNYI IAKKEDALSEVEDND
Sequences:
>Translated_575_residues MNDHILINVIILLGTAVFIVAILKRLRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGELGVVFLLFAIGLELSFERLKA MRRYVFGLGSLQVVTTAIVIAGAMVLIDGNSSAAIITGGGLALSSTALVMQVIEENRSQSTQIGRISLAILLLQDLAVVP LLVIVPLLAGNNKASLAGALGIALLKAVTALLTIFIVGRVFLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGL SLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTLSIALIGIKTLIITAFCLLFG FNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADILLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIEL GARDLTNHIIIAGLGNTGKMVARVLEAEGISYVILDLDDDRVKEELSNGLPVFKGDVSQADTLKALGTERAFAIILTMNN QVTIKKSLKTISGNYQDIPVVVKLKNLKNAREFYDLGATTIIPESYEAGLQIGGTVLKNIGISEQEINRIKVQFRLGNYI IAKKEDALSEVEDND >Mature_575_residues MNDHILINVIILLGTAVFIVAILKRLRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGELGVVFLLFAIGLELSFERLKA MRRYVFGLGSLQVVTTAIVIAGAMVLIDGNSSAAIITGGGLALSSTALVMQVIEENRSQSTQIGRISLAILLLQDLAVVP LLVIVPLLAGNNKASLAGALGIALLKAVTALLTIFIVGRVFLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGL SLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTLSIALIGIKTLIITAFCLLFG FNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADILLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIEL GARDLTNHIIIAGLGNTGKMVARVLEAEGISYVILDLDDDRVKEELSNGLPVFKGDVSQADTLKALGTERAFAIILTMNN QVTIKKSLKTISGNYQDIPVVVKLKNLKNAREFYDLGATTIIPESYEAGLQIGGTVLKNIGISEQEINRIKVQFRLGNYI IAKKEDALSEVEDND
Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]
COG id: COG0475
COG function: function code P; Kef-type K+ transport systems, membrane components
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 RCK N-terminal domain [H]
Homologues:
Organism=Homo sapiens, GI157388921, Length=383, Percent_Identity=25.8485639686684, Blast_Score=77, Evalue=5e-14, Organism=Escherichia coli, GI1786232, Length=559, Percent_Identity=33.6314847942755, Blast_Score=287, Evalue=1e-78, Organism=Escherichia coli, GI1789749, Length=563, Percent_Identity=35.3463587921847, Blast_Score=286, Evalue=2e-78, Organism=Escherichia coli, GI1786685, Length=514, Percent_Identity=29.7665369649805, Blast_Score=155, Evalue=5e-39,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006153 - InterPro: IPR020884 - InterPro: IPR004771 - InterPro: IPR016040 - InterPro: IPR003148 [H]
Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]
EC number: NA
Molecular weight: Translated: 61626; Mature: 61626
Theoretical pI: Translated: 5.38; Mature: 5.38
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNDHILINVIILLGTAVFIVAILKRLRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGEL CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHH GVVFLLFAIGLELSFERLKAMRRYVFGLGSLQVVTTAIVIAGAMVLIDGNSSAAIITGGG HHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCEEEEEECCCCEEEEECCC LALSSTALVMQVIEENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLAGNNKASLAGAL HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH GIALLKAVTALLTIFIVGRVFLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH SLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTL HHHHHHHHHHHHHHCHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH SIALIGIKTLIITAFCLLFGFNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADI HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHH LLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIELGARDLTNHIIIAGLGNTGKM HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHCCCCEEEEECCCHHHH VARVLEAEGISYVILDLDDDRVKEELSNGLPVFKGDVSQADTLKALGTERAFAIILTMNN HHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCEEEEEEEECC QVTIKKSLKTISGNYQDIPVVVKLKNLKNAREFYDLGATTIIPESYEAGLQIGGTVLKNI CEEEHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCEECCCCHHCCHHHCHHHHHHC GISEQEINRIKVQFRLGNYIIAKKEDALSEVEDND CCCHHHHCEEEEEEEECCEEEEECHHHHHHCCCCC >Mature Secondary Structure MNDHILINVIILLGTAVFIVAILKRLRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGEL CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHH GVVFLLFAIGLELSFERLKAMRRYVFGLGSLQVVTTAIVIAGAMVLIDGNSSAAIITGGG HHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCEEEEEECCCCEEEEECCC LALSSTALVMQVIEENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLAGNNKASLAGAL HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH GIALLKAVTALLTIFIVGRVFLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH SLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTL HHHHHHHHHHHHHHCHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH SIALIGIKTLIITAFCLLFGFNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADI HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHH LLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIELGARDLTNHIIIAGLGNTGKM HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHCCCCEEEEECCCHHHH VARVLEAEGISYVILDLDDDRVKEELSNGLPVFKGDVSQADTLKALGTERAFAIILTMNN HHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCEEEEEEEECC QVTIKKSLKTISGNYQDIPVVVKLKNLKNAREFYDLGATTIIPESYEAGLQIGGTVLKNI CEEEHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHCCCCEECCCCHHCCHHHCHHHHHHC GISEQEINRIKVQFRLGNYIIAKKEDALSEVEDND CCCHHHHCEEEEEEEECCEEEEECHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]
Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA