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The map label for this gene is ccmA [H]

Identifier: 157826247

GI number: 157826247

Start: 1101314

End: 1101934

Strand: Direct

Name: ccmA [H]

Synonym: A1C_06130

Alternate gene names: 157826247

Gene position: 1101314-1101934 (Clockwise)

Preceding gene: 157826246

Following gene: 157826249

Centisome position: 89.46

GC content: 30.76

Gene sequence:

>621_bases
ATGCTATCACTTCATCAATTACAATTTAATATAGAACAAAGAAATTTATTTGATCTATGTATCACTTTTCTTCCTTCTTC
TATCACCTATATAAAAGGAGCTAATGGTTGTGGTAAAAGCTCACTACTGCGAATGATAGCAGGAATTATGCAACCAAGTA
ATGGTAATATCTACTATAAAAATAGTAATATTAACAATATCCATAAACCTTACTGCACTTATATCGGTCATAATTTAGGT
CTAAAACTCGAAATGACTGTTTTTGAAAATCTAAAATTTTGGTCGGAAATTTATAATTCTGCCGAAACTATATACGCCGC
TATTCATTACTTCAAATTACAAGATTTATTAGATGAAAAATGCTATAGTTTGTCTAGTGGGATACAGAAAGTCATAGCCG
TATCAAGGCTTATTGCTTGCCAATCTGACTTATGGCTACTTGATGAAGTTGAAACTAACTTAAGTAAAGAAAATAGGGAT
TTATTAAATAATCTAATTGTCATGAAAGCAAATAGCGGCGGTATTGTTCTTCTATCATCTCATCTAGAAAGTTCTATAAA
ATCTGCACAGACATTACAACTTGATTCATTAGTAGACTTCTTTCCTAACTTGCAATGGTAA

Upstream 100 bases:

>100_bases
CAGATATAATACCGTGGTCAAGCCACAGTATCCATAAAAGCAAGGCAAACTACTAATCATTTTACTAGATACCGTGGCTT
GACCACGGTATGACAGAGAC

Downstream 100 bases:

>100_bases
ATTGCACGTCGCGACCCGGTACTAGAATTCTCACGTTACTTGCGTGTAGGCTGCAGTTCGAGGTGAAGTATCTCATTCAA
AAATTCCTTCTTATTAGCTA

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLSLHQLQFNIEQRNLFDLCITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSNGNIYYKNSNINNIHKPYCTYIGHNLG
LKLEMTVFENLKFWSEIYNSAETIYAAIHYFKLQDLLDEKCYSLSSGIQKVIAVSRLIACQSDLWLLDEVETNLSKENRD
LLNNLIVMKANSGGIVLLSSHLESSIKSAQTLQLDSLVDFFPNLQW

Sequences:

>Translated_206_residues
MLSLHQLQFNIEQRNLFDLCITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSNGNIYYKNSNINNIHKPYCTYIGHNLG
LKLEMTVFENLKFWSEIYNSAETIYAAIHYFKLQDLLDEKCYSLSSGIQKVIAVSRLIACQSDLWLLDEVETNLSKENRD
LLNNLIVMKANSGGIVLLSSHLESSIKSAQTLQLDSLVDFFPNLQW
>Mature_206_residues
MLSLHQLQFNIEQRNLFDLCITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSNGNIYYKNSNINNIHKPYCTYIGHNLG
LKLEMTVFENLKFWSEIYNSAETIYAAIHYFKLQDLLDEKCYSLSSGIQKVIAVSRLIACQSDLWLLDEVETNLSKENRD
LLNNLIVMKANSGGIVLLSSHLESSIKSAQTLQLDSLVDFFPNLQW

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI87082064, Length=185, Percent_Identity=30.2702702702703, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87081791, Length=166, Percent_Identity=31.3253012048193, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787370, Length=157, Percent_Identity=27.3885350318471, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 23364; Mature: 23364

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLHQLQFNIEQRNLFDLCITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSNGNIYYK
CCCHHHHEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEE
NSNINNIHKPYCTYIGHNLGLKLEMTVFENLKFWSEIYNSAETIYAAIHYFKLQDLLDEK
CCCCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CYSLSSGIQKVIAVSRLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKANSGGIVLLSS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCEEEEEECCCCEEEEHH
HLESSIKSAQTLQLDSLVDFFPNLQW
HHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSLHQLQFNIEQRNLFDLCITFLPSSITYIKGANGCGKSSLLRMIAGIMQPSNGNIYYK
CCCHHHHEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEE
NSNINNIHKPYCTYIGHNLGLKLEMTVFENLKFWSEIYNSAETIYAAIHYFKLQDLLDEK
CCCCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CYSLSSGIQKVIAVSRLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKANSGGIVLLSS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCEEEEEECCCCEEEEHH
HLESSIKSAQTLQLDSLVDFFPNLQW
HHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]