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The map label for this gene is udg [H]

Identifier: 157826232

GI number: 157826232

Start: 1078877

End: 1080181

Strand: Reverse

Name: udg [H]

Synonym: A1C_06055

Alternate gene names: 157826232

Gene position: 1080181-1078877 (Counterclockwise)

Preceding gene: 157826248

Following gene: 157826231

Centisome position: 87.74

GC content: 30.73

Gene sequence:

>1305_bases
ATGAATATTACATTTATCGGTAGCGGATATGTTGGATTAGTCTCAGGTATTATTATGAGCTATTTAGGCCATAATGTTAC
TTGTCTTGATAATGATGAGGTGAAAATATCCAAATTAAATAAGCAAATATTGCCGATTTATGAAGCTAAGCTTGATGAAT
ATCTTAAGCAAGCTTTAGAAGCTAATAGGTTAAAATTTACAAATATTTATAATAATGAACTTCAAAATGCCGAGGCAATA
TTTATTACGGTCGGTACGCCTTCAAAAGAGTCGGGAGAAGCAGATTTAAAATATGTCTATGATGCTATTAATAAAGTTTC
TAAGCATATAAATAAAGATTGTTTAATAGTCATAAAATCTACTGTTCCGCCTGGTAGTTGCAGTAATATTATAGCTTCTT
TAAACTCACAAGGTTTTTTATTTAATGTTGCTTCTAATCCTGAGTTTTTAAGAGAGGGCAATGCGGTAGAAGATTTTTTA
TATCCTGATCGTATAGTTATCGGTGTACATGATAAAGAATCAGAGGAAATTTTACGAAAAATTTATGCACCTTTAATAGA
ACAAGGAGCAAAGTTTGTGATTACCGATTTAGTGACGAGTGAGCTTATTAAATATGCTTCAAATAGTTTTTTAGCTACCA
AAATTGCTTTTATTAACGAAATGGCTGACTTATGCGAAAAAATTGGCGGCAATATTAAAGATTTATCTAAAGGTGTAGGA
CTTGATCAAAGAATCGGTCAAGATTTTTTAAATGCAGGTCCTGGTTTTGGTGGTTCATGTTTTCCAAAAGATATTCTAGC
ATTAAATAATCTTGTAGAAAATCATCATATCGATTGTAAGATTCTTAAGGCAGTAATTACAAGTAATAAGCAGCGTCCAA
GTAATATGGTAGATAAAATAGCTACTTTGTTAGACGGAGATTTAAAAGGTAAAAATATAGCAATTTTAGGCTTAACATAC
AAAGCAGGAACAGATGATGTTAGGGCCAGTCCTGCAATCGAAATTGTAAAGATCTTATTAAATAAAGATGTATATGTTAA
AGCATTTGATCCTATTGGGCTTGAAAATGCTAAAAAGAATTTAGAACATAAAAATTTGCTATATTTAGATTCGGTAGATG
AAGCCTGTAAATCAGTAGATATTATAGTTATTGCAACCGAATGGTTAGAATTCAAAGAACTTAATTGGCATGGAATTTAT
AATTTAGTACAATCCACGATAATTATTGACCTTAGAAACATACTAGATAATGAAGCAATGAGAAAAATCGGTTTTAGATA
TTATGCAGTTGGGAGTAAGATGTAG

Upstream 100 bases:

>100_bases
GAAGTTGATCTTCGTCTATACTACTCTTCATTTTATTTGAGGTATACACTTGGAATATAACGTATAATTTAAAAATTTAA
TATAAAAATCACAAAAAATT

Downstream 100 bases:

>100_bases
CCTTGGTGTATCGAACGGAAAATACACTCGGTGTTATACCGCGGCTTGACCACAGTATCAAAAAAAAATTAAAAAAGACT
GGACCAAGTGGTCAAGCAAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNITFIGSGYVGLVSGIIMSYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALEANRLKFTNIYNNELQNAEAI
FITVGTPSKESGEADLKYVYDAINKVSKHINKDCLIVIKSTVPPGSCSNIIASLNSQGFLFNVASNPEFLREGNAVEDFL
YPDRIVIGVHDKESEEILRKIYAPLIEQGAKFVITDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVG
LDQRIGQDFLNAGPGFGGSCFPKDILALNNLVENHHIDCKILKAVITSNKQRPSNMVDKIATLLDGDLKGKNIAILGLTY
KAGTDDVRASPAIEIVKILLNKDVYVKAFDPIGLENAKKNLEHKNLLYLDSVDEACKSVDIIVIATEWLEFKELNWHGIY
NLVQSTIIIDLRNILDNEAMRKIGFRYYAVGSKM

Sequences:

>Translated_434_residues
MNITFIGSGYVGLVSGIIMSYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALEANRLKFTNIYNNELQNAEAI
FITVGTPSKESGEADLKYVYDAINKVSKHINKDCLIVIKSTVPPGSCSNIIASLNSQGFLFNVASNPEFLREGNAVEDFL
YPDRIVIGVHDKESEEILRKIYAPLIEQGAKFVITDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVG
LDQRIGQDFLNAGPGFGGSCFPKDILALNNLVENHHIDCKILKAVITSNKQRPSNMVDKIATLLDGDLKGKNIAILGLTY
KAGTDDVRASPAIEIVKILLNKDVYVKAFDPIGLENAKKNLEHKNLLYLDSVDEACKSVDIIVIATEWLEFKELNWHGIY
NLVQSTIIIDLRNILDNEAMRKIGFRYYAVGSKM
>Mature_434_residues
MNITFIGSGYVGLVSGIIMSYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALEANRLKFTNIYNNELQNAEAI
FITVGTPSKESGEADLKYVYDAINKVSKHINKDCLIVIKSTVPPGSCSNIIASLNSQGFLFNVASNPEFLREGNAVEDFL
YPDRIVIGVHDKESEEILRKIYAPLIEQGAKFVITDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVG
LDQRIGQDFLNAGPGFGGSCFPKDILALNNLVENHHIDCKILKAVITSNKQRPSNMVDKIATLLDGDLKGKNIAILGLTY
KAGTDDVRASPAIEIVKILLNKDVYVKAFDPIGLENAKKNLEHKNLLYLDSVDEACKSVDIIVIATEWLEFKELNWHGIY
NLVQSTIIIDLRNILDNEAMRKIGFRYYAVGSKM

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=465, Percent_Identity=33.9784946236559, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI296040438, Length=364, Percent_Identity=33.7912087912088, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI296040443, Length=457, Percent_Identity=29.9781181619256, Blast_Score=182, Evalue=7e-46,
Organism=Escherichia coli, GI1788340, Length=360, Percent_Identity=30.5555555555556, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI48994968, Length=413, Percent_Identity=25.181598062954, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560350, Length=463, Percent_Identity=34.9892008639309, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI17136908, Length=464, Percent_Identity=34.4827586206897, Blast_Score=238, Evalue=5e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48145; Mature: 48145

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITFIGSGYVGLVSGIIMSYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALE
CEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHHHHH
ANRLKFTNIYNNELQNAEAIFITVGTPSKESGEADLKYVYDAINKVSKHINKDCLIVIKS
CCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEC
TVPPGSCSNIIASLNSQGFLFNVASNPEFLREGNAVEDFLYPDRIVIGVHDKESEEILRK
CCCCCCHHHHHHHCCCCCEEEEECCCCHHHHCCCCHHHHCCCCEEEEEECCCCHHHHHHH
IYAPLIEQGAKFVITDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVG
HHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
LDQRIGQDFLNAGPGFGGSCFPKDILALNNLVENHHIDCKILKAVITSNKQRPSNMVDKI
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
ATLLDGDLKGKNIAILGLTYKAGTDDVRASPAIEIVKILLNKDVYVKAFDPIGLENAKKN
HHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHC
LEHKNLLYLDSVDEACKSVDIIVIATEWLEFKELNWHGIYNLVQSTIIIDLRNILDNEAM
CCCCCEEEEECHHHHHCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKIGFRYYAVGSKM
HHHCCEEEEECCCC
>Mature Secondary Structure
MNITFIGSGYVGLVSGIIMSYLGHNVTCLDNDEVKISKLNKQILPIYEAKLDEYLKQALE
CEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHHHHH
ANRLKFTNIYNNELQNAEAIFITVGTPSKESGEADLKYVYDAINKVSKHINKDCLIVIKS
CCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEC
TVPPGSCSNIIASLNSQGFLFNVASNPEFLREGNAVEDFLYPDRIVIGVHDKESEEILRK
CCCCCCHHHHHHHCCCCCEEEEECCCCHHHHCCCCHHHHCCCCEEEEEECCCCHHHHHHH
IYAPLIEQGAKFVITDLVTSELIKYASNSFLATKIAFINEMADLCEKIGGNIKDLSKGVG
HHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
LDQRIGQDFLNAGPGFGGSCFPKDILALNNLVENHHIDCKILKAVITSNKQRPSNMVDKI
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHH
ATLLDGDLKGKNIAILGLTYKAGTDDVRASPAIEIVKILLNKDVYVKAFDPIGLENAKKN
HHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHC
LEHKNLLYLDSVDEACKSVDIIVIATEWLEFKELNWHGIYNLVQSTIIIDLRNILDNEAM
CCCCCEEEEECHHHHHCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKIGFRYYAVGSKM
HHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA