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The map label for this gene is engA [H]

Identifier: 157826088

GI number: 157826088

Start: 936263

End: 937606

Strand: Direct

Name: engA [H]

Synonym: A1C_05240

Alternate gene names: 157826088

Gene position: 936263-937606 (Clockwise)

Preceding gene: 157826087

Following gene: 157826091

Centisome position: 76.05

GC content: 34.15

Gene sequence:

>1344_bases
ATGACTAAAAAAATCATTGCTTTAGTTGGTCGTCCGAATGTAGGCAAATCAACGCTTTTCAATAGATTAAGCATACGTAA
AAAAGCTATCGTTCACGATTTGCCAGGCATTACTAGAGATAGAAAATATACAGATGGTAAAATCGGATCTTTTGAATTTT
TGTTAATTGATACCCCAGGACTTGAAGAGAATCATGATAGTATGGGCGCAAGGTTAATGGAACAGACTACTAAAGCAATT
TTAGAGGCAGATTTAATTTGTTTTATGGTTGACGGTAGAAGCGGAATATTGCCCAATGATAAGCTACTTGGTAGCTTTGT
TAGAAAGTATAATAAGCCTGCTATATTGGTAGTTAATAAATGCGAGAAAGCTTTTGATTTTGATAAAGAGTACTACAAAT
TAGGGTTTGATAGTATGGTGACTATCTCTGCCGAGCATGGCACAGGCTTAATTGATTTATATGACGAGATTATCACCAAG
TTACCTGAAGAAGAATCAATAGAGACAAATATAGCTGATCCAATTAAAGGAGATTATTTGCAGATAGTAGTTAGTGGCAG
ACCTAACGCCGGAAAATCTACTTTTATAAACGCTCTTATTAATGATGAAAGATTATTAACCGGGCCCGAAGCCGGCATTA
CTCGTGAATCGATTGAAATTGATTGGCACTATAAAAATAATCACATTAAATTAATCGATACAGCAGGACTCCGCAAGAAA
TCTACTATTACAGAGTCTTTAGAAAAATTATCGGCATCAGATGCTATTAACTCTATTAAATTTGCTAATACCGTAATCTT
AATGATTGATGCTTTAGCCCCTTTAAAACAGCAAGATTTAAATATTGCAAGCCATGTGGTAAATGAGGGGAGAGGTATAG
TTATAGTAGTGAATAAATGGGATCTAGTCAAAGAATCCAAAAAAGAAGCATTTCAGGAAGAATTTTATTATCAGATAAAT
ACTCATCTGCCTCAGGTTAAAGGTGTACCAGTGCTATTTATTTCAGCAATAAATAAACAAAATATAGAGCAGGTTTTAGA
TTCTTGTCTTAAAATCTATAAAATTTGGAATAAGAAAATAGCTACTAGCAAATTAAATGAATGGCTTAATTTTACTACGG
AAGCACATCCTTTGCCGTTACAAAAAGGCGGCAGAAGAGTGCGTGTAAAATATATGACTCAAACCAAAACTCGCCCGCCT
ACTTTCAAATTATTCTCCAATAATCCGGAAAAAATTACCGATAGCTATACTAGGTATTTAGTAAATAATATGCGTGATGC
TTTTGACATGCCAGGCATTCCTATTAGATTCACTTATGTAAAAACCAAAAACCCTTATGTGTAG

Upstream 100 bases:

>100_bases
TATACGGCATATTAATAAAAAATACACCTATTATAATAGCAAATATAGTAGGTTTTATTGGAGCATTATTAGTTCTCTTA
ACCATAATAATATATTAATA

Downstream 100 bases:

>100_bases
TTTGAAACTAAATCTTTTTAGAAATGTTTACAGCTCCAAGCATAGCAAGATATGAATTAGATATCTTTAAGCTATTTAAT
ATAGCATGAGCTAAAGTAGC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTKKIIALVGRPNVGKSTLFNRLSIRKKAIVHDLPGITRDRKYTDGKIGSFEFLLIDTPGLEENHDSMGARLMEQTTKAI
LEADLICFMVDGRSGILPNDKLLGSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMVTISAEHGTGLIDLYDEIITK
LPEEESIETNIADPIKGDYLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWHYKNNHIKLIDTAGLRKK
STITESLEKLSASDAINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRGIVIVVNKWDLVKESKKEAFQEEFYYQIN
THLPQVKGVPVLFISAINKQNIEQVLDSCLKIYKIWNKKIATSKLNEWLNFTTEAHPLPLQKGGRRVRVKYMTQTKTRPP
TFKLFSNNPEKITDSYTRYLVNNMRDAFDMPGIPIRFTYVKTKNPYV

Sequences:

>Translated_447_residues
MTKKIIALVGRPNVGKSTLFNRLSIRKKAIVHDLPGITRDRKYTDGKIGSFEFLLIDTPGLEENHDSMGARLMEQTTKAI
LEADLICFMVDGRSGILPNDKLLGSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMVTISAEHGTGLIDLYDEIITK
LPEEESIETNIADPIKGDYLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWHYKNNHIKLIDTAGLRKK
STITESLEKLSASDAINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRGIVIVVNKWDLVKESKKEAFQEEFYYQIN
THLPQVKGVPVLFISAINKQNIEQVLDSCLKIYKIWNKKIATSKLNEWLNFTTEAHPLPLQKGGRRVRVKYMTQTKTRPP
TFKLFSNNPEKITDSYTRYLVNNMRDAFDMPGIPIRFTYVKTKNPYV
>Mature_446_residues
TKKIIALVGRPNVGKSTLFNRLSIRKKAIVHDLPGITRDRKYTDGKIGSFEFLLIDTPGLEENHDSMGARLMEQTTKAIL
EADLICFMVDGRSGILPNDKLLGSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMVTISAEHGTGLIDLYDEIITKL
PEEESIETNIADPIKGDYLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWHYKNNHIKLIDTAGLRKKS
TITESLEKLSASDAINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRGIVIVVNKWDLVKESKKEAFQEEFYYQINT
HLPQVKGVPVLFISAINKQNIEQVLDSCLKIYKIWNKKIATSKLNEWLNFTTEAHPLPLQKGGRRVRVKYMTQTKTRPPT
FKLFSNNPEKITDSYTRYLVNNMRDAFDMPGIPIRFTYVKTKNPYV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=36.3247863247863, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI1788919, Length=168, Percent_Identity=36.3095238095238, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367268, Length=87, Percent_Identity=41.3793103448276, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=125, Percent_Identity=34.4, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50688; Mature: 50557

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKIIALVGRPNVGKSTLFNRLSIRKKAIVHDLPGITRDRKYTDGKIGSFEFLLIDTPG
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
LEENHDSMGARLMEQTTKAILEADLICFMVDGRSGILPNDKLLGSFVRKYNKPAILVVNK
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEC
CEKAFDFDKEYYKLGFDSMVTISAEHGTGLIDLYDEIITKLPEEESIETNIADPIKGDYL
CHHHHCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
QIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWHYKNNHIKLIDTAGLRKK
EEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCEECEEEEEEEEECCEEEEEECCCCCCH
STITESLEKLSASDAINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRGIVIVVNKW
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCHHHHCCHHHHHHHHCCCEEEEEECCC
DLVKESKKEAFQEEFYYQINTHLPQVKGVPVLFISAINKQNIEQVLDSCLKIYKIWNKKI
HHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHH
ATSKLNEWLNFTTEAHPLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYL
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
VNNMRDAFDMPGIPIRFTYVKTKNPYV
HHHHHHHHCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TKKIIALVGRPNVGKSTLFNRLSIRKKAIVHDLPGITRDRKYTDGKIGSFEFLLIDTPG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
LEENHDSMGARLMEQTTKAILEADLICFMVDGRSGILPNDKLLGSFVRKYNKPAILVVNK
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEC
CEKAFDFDKEYYKLGFDSMVTISAEHGTGLIDLYDEIITKLPEEESIETNIADPIKGDYL
CHHHHCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
QIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWHYKNNHIKLIDTAGLRKK
EEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCEECEEEEEEEEECCEEEEEECCCCCCH
STITESLEKLSASDAINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRGIVIVVNKW
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCHHHHCCHHHHHHHHCCCEEEEEECCC
DLVKESKKEAFQEEFYYQINTHLPQVKGVPVLFISAINKQNIEQVLDSCLKIYKIWNKKI
HHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHH
ATSKLNEWLNFTTEAHPLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYL
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
VNNMRDAFDMPGIPIRFTYVKTKNPYV
HHHHHHHHCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA